Ukujova kweTemozolomide

-Delile

• Ngaphambi kokuthola i-temozolomide,
• I-Temozolomide ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

I-Temozolomide isetshenziselwa ukwelapha izinhlobo ezithile zezicubu zobuchopho. I-Temozolomide isekilasini lemithi ebizwa ngama-alkylating agents. Isebenza ngokunciphisa noma ukumisa ukukhula kwamangqamuzana omdlavuza emzimbeni wakho.

Umjovo weTemozolomide uza njengempuphu ezokwengezwa kuketshezi bese ujovwa ngaphezu kwemizuzu engama-90 ngemithambo (emthanjeni) ngudokotela noma unesi. Kuvame ukujova kanye ngosuku. Kwezinye izinhlobo zamathumba obuchopho, i-temozolomide inikezwa nsuku zonke izinsuku ezingama-42 kuye kwezingama-49. Ngemuva kwalokho, ngemuva kwekhefu lezinsuku ezingama-28, linganikezwa kanye ngosuku izinsuku ezi-5 zilandelana, lilandelwe ikhefu lezinsuku ezingama-23 ngaphambi kokuphinda umjikelezo wesilinganiso olandelayo. Ngokwelashwa kwezinye izinhlobo zamathumba obuchopho, i-temozolomide inikezwa kanye ngosuku izinsuku ezi-5 zilandelana, kulandelwa ikhefu lezinsuku ezingama-23 ngaphambi kokuphinda umjikelezo wesilinganiso olandelayo. Isikhathi sokwelashwa sincike ekutheni umzimba wakho usabela kahle kanjani kiso kanye nohlobo lomdlavuza onawo.

Udokotela wakho angadinga ukubambezela ukwelashwa kwakho noma alungise umthamo wakho ngokuya ngempendulo yakho ekwelashweni nanoma yimiphi imiphumela emibi oyitholayo. Khuluma nodokotela wakho mayelana nokuthi uzizwa kanjani ngenkathi welashwa nge-temozolomide.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola i-temozolomide,

• Tshela udokotela kanye nosokhemisi wakho uma une-aleji ku-temozolomide, i-dacarbazine (i-DTIC-Dome) noma yimiphi eminye imithi, noma yiziphi izithako zomjovo we-temozolomide. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: carbamazepine (Carbatrol, Epitol, Tegretol); co-trimoxazole (Bactrim, Septra); i-phenytoin (iDilantin, Phenytek); i-steroids efana ne-dexamethasone (i-Decadron, i-Dexone), i-methylprednisolone (i-Medrol) ne-prednisone (i-Deltasone); ne-valproic acid (iStavzor, ​​iDepakene).
• tshela udokotela wakho uma uke waba nesifo sezinso noma sesibindi.
• kufanele wazi ukuthi i-temozolomide ingaphazamisa ukukhiqizwa kwesidoda emadodeni. Kodwa-ke, akufanele ucabange ukuthi awukwazi ukukhulelisa omunye umuntu. Tshela udokotela wakho uma ukhulelwe noma uhlela ukukhulelwa, noma uma uhlela ukuba nobaba wengane. Wena noma umlingani wakho akufanele ukhulelwe ngenkathi uthola i-temozolomide. Sebenzisa indlela ethembekile yokulawula inzalo ukuvimbela ukukhulelwa. Uma ukhulelwa ngenkathi uthola i-temozolomide, shayela udokotela wakho. I-Temozolomide ingalimaza umbungu.
• tshela udokotela wakho uma uncelisa. Akufanele uncelise ibele ngenkathi uthola i-temozolomide.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

I-Temozolomide ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isicanucanu
• ukuhlanza
• isifo sohudo
• ukuqunjelwa
• ukulahlekelwa isifiso sokudla
• izilonda emlonyeni nasemphinjeni
• ikhanda
• isikhumba esiphaphathekile
• ukungabi namandla
• ukulahlekelwa ibhalansi noma ukuxhumanisa
• ukuquleka
• isiyezi
• ukulahleka kwezinwele
• ukuqwasha
• izinkinga zememori
• ubuhlungu, ukulunywa, ukuvuvukala, noma ubomvu endaweni lapho umjovo wafakwa khona
• izinguquko embonweni

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukopha okungajwayelekile noma ukulinyazwa
• okubomvu noma okumnyama, izitulo zokulinda
• umchamo obomvana, obomvu, noma onsundu
• ukukhwehlela noma ukuphalaza igazi noma into ebukeka njengezizathu zekhofi
• umkhuhlane, umphimbo obuhlungu, ukukhwehlela okuqhubekayo nokucinana, noma ezinye izimpawu zokutheleleka
• ukukhathala okungajwayelekile noma ubuthakathaka
• ukuqubuka
• ayikwazi ukuhambisa uhlangothi olulodwa lomzimba
• ukuphelelwa umoya
• isithuthwane
• ukuphuzi kwesikhumba noma kwamehlo
• ubuhlungu engxenyeni engenhla kwesokudla yesisu
• ukuncipha kokuchama

I-Temozolomide ingakhuphula ubungozi bokuthi uzoba neminye imidlavuza. Khuluma nodokotela wakho ngezingozi zokuthatha i-temozolomide.

I-Temozolomide ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• ukopha okungajwayelekile noma ukulinyazwa
• okubomvu noma okumnyama, izitulo zokulinda
• umchamo obomvana, obomvu, noma onsundu
• ukukhwehlela noma ukuphalaza igazi noma into ebukeka njengezizathu zekhofi
• umkhuhlane, umphimbo obuhlungu, ukukhwehlela okuqhubekayo nokucinana, noma ezinye izimpawu zokutheleleka

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda ukuhlolwa kwelabhorethri ngaphambi, ngesikhathi, nangemva kokwelashwa kwakho ukuhlola ukuphendula komzimba wakho kanye ne-temozolomide ukubona ukuthi amaseli akho egazi ayathinteka yini yilomuthi.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Temodar^®