Linaclotide

-Delile

• Ngaphambi kokuthatha i-linaclotide,
• ILinaclotide ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, yeka ukuthatha i-linaclotide bese ushayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

ILinaclotide ingadala ukuphelelwa ngamanzi emzimbeni okusongela izimpilo kumagundane amancane aselebhu. Izingane ezingaphansi kweminyaka engu-6 ubudala akufanele zithathe i-linaclotide. Izingane ezineminyaka engu-6 kuya kwengu-17 ubudala akufanele zithathe i-linaclotide.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa nge-linaclotide futhi isikhathi ngasinye lapho ugcwalisa umuthi wakho. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) noma iwebhusayithi yomkhiqizi ukuthola i-Medication Guide.

Khuluma nodokotela wakho ngezingozi zokuthatha i-linaclotide.

ILinaclotide isetshenziswa kubantu abadala ukwelapha amathumbu esifo ngokucasulwa (IBS-C; isimo esidala ubuhlungu besisu noma amajaqamba, ukuqunjelwa, nokuhamba okungajwayelekile noma okunzima) nokuqunjelwa okungapheli kwe-idiopathic (CIC; ukudlula okunzima noma okungajwayelekile kwezitulo lokho ihlala izinyanga ezintathu noma ngaphezulu futhi ayibangelwa yisifo noma umuthi). ILinaclotide isekilasini lemithi ebizwa ngama-guanylate cyclase-C agonists. Isebenza ngokwandisa ukuhamba kokudla nemfucuza esiswini nasemathunjini.

ILinaclotide iza njengephilisi elizothathwa ngomlomo. Imvamisa kuthathwa kanye ngosuku esiswini esingenalutho, okungenani imizuzu engamashumi amathathu ngaphambi kokudla kokuqala kosuku. Thatha i-linaclotide ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-linaclotide njengoba nje kuqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Gwinya wonke amaphilisi; ungawahlukanisi, ungawahlafune noma uwagxoze.

ILinaclotide ilawula izimpawu ze-IBS-C ne-CIC, kepha ayizelaphi lezi zimo. Izimpawu zakho zokuqunjelwa zingathuthuka evikini elingu-1, futhi kungathatha isikhashana ukuthi ubuhlungu besisu sakho buthuthuke. Qhubeka uthathe i-linaclotide noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-linaclotide ngaphandle kokukhuluma nodokotela wakho. Uma uyeka ukuthatha i-linaclotide, izimpawu zakho zingabuya cishe ngeviki elilodwa.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-linaclotide,

• Tshela udokotela kanye nosokhemisi wakho uma une-allergies ku-linaclotide, noma imuphi omunye umuthi, noma iziphi izithako ezikuma-capsules we-linaclotide. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• Tshela udokotela wakho uma uvinjelwe esiswini noma emathunjini akho. Udokotela wakho mhlawumbe uzokutshela ukuthi ungathathi i-linaclotide.
• tshela udokotela wakho uma ngabe uke waba nanoma yiziphi ezinye izimo zezokwelapha.

• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha i-linaclotide, shayela udokotela wakho.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Uma ukhumbula umthamo ongabanjwanga ngaphambi kokudla, thatha umthamo owulahlekile ngokushesha uma uwukhumbula. Uma usudlile, hlola udokotela wakho ngaphambi kokuthatha umthamo ongabanjwanga. Uma sekusondele isikhathi somthamo olandelayo, weqa umthamo ophuthelwe bese uqhubeka nesimiso sakho sokulinganisa okujwayelekile. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

ILinaclotide ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isifo sohudo
• ubuhlungu besisu
• ukuvuvukala noma ukuzwa ukugcwala noma ingcindezi endaweni yesisu
• igesi
• ikhanda

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, yeka ukuthatha i-linaclotide bese ushayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ubuhlungu obungavamile noma obukhulu besisu
• okubomvu okukhanyayo noma okumnyama, izitulo zokulinda
• isifuba

ILinaclotide ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese). Ungayikhiphi i-desiccant (i-agent eyomisa) ebhodleleni, uma inikiwe.

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• isifo sohudo

Gcina wonke ama-aphoyintimenti nodokotela wakho.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Linzess^®