Ukujova kwe-Obinutuzumab

-Delile

• Ngaphambi kokuthola umjovo we-obinutuzumab,
• Umjovo we-Obinutuzumab ungadala imiphumela emibi. Tshela udokotela wakho uma lesi sibonakaliso sinzima noma singapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SEXWAYISO noma INDLELA, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

Kungenzeka ukuthi usungenwe yi-hepatitis B (igciwane elithelela isibindi futhi lingadala ukulimala kwesibindi) kepha ungabi nazimpawu zesifo. Kulokhu, umjovo we-obinutuzumab ungakhuphula ubungozi bokuthi ukutheleleka kwakho kuzoba kubi kakhulu noma kusongele impilo futhi uzoba nezimpawu. Tshela udokotela wakho uma ngabe uke waba nokutheleleka ngegciwane le-hepatitis B. Udokotela wakho uzoku-oda ukuhlolwa kwegazi ukuze abone ukuthi une-virus engasebenzi ye-hepatitis B engasebenzi. Uma kunesidingo, udokotela wakho angakunika imithi yokwelapha lesi sifo. Udokotela wakho futhi uzokuqapha ngezimpawu zokutheleleka kwesifo sokusha kwesibindi kohlobo B ngesikhathi nangezinyanga ezimbalwa ngemuva kokwelashwa kwakho nge-obinutuzumab. Uma uhlangabezana nalezi zimpawu ezilandelayo ngesikhathi noma ngemuva kokwelashwa kwakho, shayela udokotela wakho ngokushesha: ukukhathala ngokweqile, ukuphuzi kwesikhumba noma kwamehlo, ukulahlekelwa isifiso sokudla, isicanucanu noma ukuhlanza, ubuhlungu besisu, noma umchamo omnyama.

Abanye abantu abathole i-obinutuzumab bahlakulele i-leukoencephalopathy eqhubekayo ye-multifocal leukoencephalopathy (i-PML; ukutheleleka okungavamile kobuchopho okungenakulashwa, ukuvinjelwa, noma ukwelashwa okuvame ukubangela ukufa noma ukukhubazeka okukhulu) ngesikhathi sokwelashwa kwabo.Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: izinguquko ezintsha noma ezingazelelwe ekucabangeni noma ekudidekeni, isiyezi, ukulahlekelwa ibhalansi, ubunzima bokukhuluma noma ukuhamba, ushintsho olusha noma oluzumayo embonweni, noma ezinye izimpawu ezingavamile ezithi gwa gqa.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile ukuze ahlole impendulo yomzimba wakho kumjovo we-obinutuzumab.

Khuluma nodokotela wakho ngezingozi zokuthola umjovo we-obinutuzumab.

Umjovo we-Obinutuzumab usetshenziswa ne-chlorambucil (Leukeran) ukwelapha i-lymphocytic leukemia (CLL; uhlobo lomdlavuza wamaseli amhlophe egazi). Ibuye isetshenziswe yodwa noma nge-bendamustine (Bendeka, Treanda) noma eminye imithi yokwelapha ngamakhemikhali ukwelapha i-follicular non-Hodgkin's lymphoma (NHL; umdlavuza wegazi okhula kancane) kubantu abaqala ukwelashwa noma abagulayo ababuyile noma ayithuthukisiwe ngemuva kokuthola eminye imishanguzo (i-chemotherapy). Umjovo we-Obinutuzumab usesigabeni semithi ebizwa ngama-antibody monoclonal. Isebenza ngokubulala amangqamuzana omdlavuza.

Umjovo we-Obinutuzumab uza njengesixazululo (uketshezi) ukwengezwa kuketshezi nokujova ngomjovo (emthanjeni) ngudokotela noma umhlengikazi ehhovisi lezokwelapha noma esibhedlela. Udokotela wakho uzokhetha ishejuli yokukunika umjovo we-obinutuzumab kanye neminye imithi engcono kakhulu yokwelapha isimo sakho.

Udokotela wakho angadinga ukuphazamisa noma ayeke ukwelashwa kwakho uma uhlangabezana nemiphumela ethile emibi. Udokotela wakho uzokunika eminye imishanguzo yokuvikela noma yokwelapha imiphumela ethile engemihle ngaphambi kokuthola umthamo ngamunye womjovo we-obinutuzumab. Tshela udokotela noma umhlengikazi wakho uma uhlangabezana nanoma ikuphi kokulandelayo phakathi noma phakathi kwamahora angama-24 ngemuva kokuthola i-obinutuzumab: isiyezi, ikhanda elikhanyayo, ukuquleka, ukushaya kwenhliziyo okusheshayo, ubuhlungu besifuba, ukuphefumula kanzima, ukuvuvukala komphimbo, isicanucanu, ukuhlanza, ukukhathala, uhudo, ukubomvu ngokungazelelwe kobuso, intamo, noma isifuba esingenhla, ikhanda elibuhlungu, ukugodola nomkhuhlane.

Qiniseka ukuthi utshela udokotela wakho ukuthi uzizwa kanjani ngesikhathi sokwelashwa kwakho ngomjovo we-obinutuzumab.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola umjovo we-obinutuzumab,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-obinutuzumab, noma imiphi eminye imithi, noma yiziphi izithako zomjovo we-obinutuzumab. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukusho noma yimiphi imithi yomfutho wegazi ophezulu. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• utshele udokotela wakho uma uke waba nesifo senhliziyo noma samaphaphu noma wake waba naso. Phinda utshele udokotela wakho uma unanoma yiluphi uhlobo lokutheleleka manje noma uma uke waba nokutheleleka okungeke kwaphela noma ukutheleleka okuzayo nokudlulayo.
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthola umjovo we-obinutuzumab, shayela udokotela wakho.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi uthola umjovo we-obinutuzumab.
• ungenayo imigomo ngaphandle kokukhuluma nodokotela wakho.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Uma uphuthelwa isikhathi sokuthola i-obinutuzumab, shayela udokotela wakho ngokushesha.

Umjovo we-Obinutuzumab ungadala imiphumela emibi. Tshela udokotela wakho uma lesi sibonakaliso sinzima noma singapheli:

• ubuhlungu bemisipha noma bamalunga

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SEXWAYISO noma INDLELA, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• umkhuhlane, ukubanda, ukukhwehlela, umphimbo obuhlungu, noma ezinye izimpawu zokutheleleka
• ukopha okungajwayelekile noma ukulinyazwa
• ubuhlungu besifuba, ubuhlungu bamalunga, nomkhuhlane
• kunciphise imvamisa yokuchama noma inani

Umjovo we-Obinutuzumab ungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthola lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nomjovo we-obinutuzumab.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Gazyva^®