Empagliflozin

-Delile

• Ngaphambi kokuthatha i-empagliflozin,
• Lo muthi ungadala ushintsho kushukela wakho wegazi. Kufanele wazi izimpawu zikashukela wegazi ophansi futhi ophakeme nokuthi yini okufanele uyenze uma unalezi zimpawu.
• I-Empagliflozin ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:
• Uma uhlangabezana nalezi zimpawu ezilandelayo, yeka ukuthatha i-empagliflozin bese ushayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
• Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo ze-ketoacidosis, yeka ukuthatha i-empagliflozin bese ushayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo. Uma kunokwenzeka, hlola ama-ketone emchameni wakho uma unalezi zimpawu, noma ngabe ushukela wegazi lakho ungaphansi kuka-250 mg / dL:

I-Empagliflozin isetshenziswa kanye nokudla nokuvivinya umzimba, futhi kwesinye isikhathi neminye imithi, ukwehlisa amazinga kashukela egazini kubantu abanesifo sikashukela sohlobo 2 (isimo lapho ushukela wegazi uphakeme kakhulu ngoba umzimba awukhiqizi noma usebenzise i-insulin ngokujwayelekile). I-Empagliflozin nayo isetshenziselwa ukunciphisa ubungozi bokushaywa unhlangothi, isifo senhliziyo, noma ukufa kubantu abane-type 2 yesifo sikashukela kanye nesifo senhliziyo nesifo segazi. Kusesigabeni semithi ebizwa nge-sodium-glucose co-transporter 2 (SGLT2) inhibitors. I-Empagliflozin yehlisa ushukela wegazi ngokubangela izinso ukususa i-glucose eningi emchameni. Ayisetshenziselwa ukwelapha uhlobo lwesifo sikashukela sohlobo 1 (isimo lapho umzimba ungakhiqizi i-insulin ngakho-ke, awukwazi ukulawula inani likashukela egazini) noma i-ketoacidosis yesifo sikashukela (isimo esibi esingakhula uma ushukela wegazi ongelashwa ).

Ngokuhamba kwesikhathi, abantu abanesifo sikashukela kanye noshukela ophakeme wegazi bangakhula babe nezinkinga ezinkulu noma ezisongela impilo, kufaka phakathi isifo senhliziyo, isifo sohlangothi, izinkinga zezinso, ukulimala kwemizwa nezinkinga zamehlo. Ukuthatha imishanguzo, ukwenza ushintsho endleleni ophila ngayo (isb., Ukudla, ukuzivocavoca umzimba, ukuyeka ukubhema), nokuhlola njalo ushukela wegazi lakho kungasiza ukuphatha isifo sikashukela nokuthuthukisa impilo yakho. Lokhu kwelashwa kunganciphisa namathuba akho okuhlaselwa yisifo senhliziyo, isifo sohlangothi, noma ezinye izinkinga ezihlobene nesifo sikashukela njengokuhluleka kwezinso, ukulimala kwemizwa (okundikindiki, imilenze ebandayo noma izinyawo; ukwehla kwekhono lezocansi kwabesilisa nabesifazane), izinkinga zamehlo, kufaka phakathi izinguquko noma ukulahleka kombono, noma isifo sezinsini. Udokotela wakho nabanye abahlinzeki bezokunakekelwa kwezempilo bazokhuluma nawe ngendlela engcono yokuphatha isifo sikashukela.

I-Empagliflozin iza njengethebhulethi ukuthatha ngomlomo. Imvamisa kuthathwa kanye ngosuku ekuseni noma ngaphandle kokudla. Thatha i-empagliflozin ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-empagliflozin njengoba nje kuyalelwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Udokotela wakho angakuqala ngomthamo ophansi we-empagliflozin futhi akhuphule umthamo wakho lapho kudingeka.

I-Empagliflozin ilawula uhlobo lwesifo sikashukela esingu-2 kodwa ayiselaphi. Qhubeka uthathe i-empagliflozin noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-empagliflozin ngaphandle kokukhuluma nodokotela wakho.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-empagliflozin,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-empagliflozin, noma imiphi eminye imithi, noma iziphi izithako ezikumaphilisi e-empagliflozin. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma ikuphi kokulandelayo: ama-angiotensin-converting enzyme (ACE) inhibitors anjenge benazepril (Lotensin, eLotrel), captopril, enalapril (Vasotec, in Vaseretic), fosinopril, lisinopril (in Zestoretic), moexipril (Univasc, Uniretic), perindopril (Aceon, in Prestalia), quinapril (Accupril, in Accuretic, in Quinaretic), ramipril (Altace), kanye ne-trandolapril (Mavik, eTarka); ama-angiotensin receptor blockers afana ne-azilsartan (Edarbi, e-Edarbyclor), candesartan (Atacand, e-Atacand HCT), eprosartan (Teveten), irbesartan (Avapro, e-Avalide), losartan (Cozaar, e-Hyzaar), olmesartan (Benicar, e-Azor, e-Benicar HCT, e-Tribenzor), e-telmisartan (Micardis, e-Micardis HCT, e-Twynsta), nase-valsartan (Diovan, e-Diovan HCT, e-Exforge); i-aspirin neminye imishanguzo yokulwa nokuvuvukala (ama-NSAID) njenge-ibuprofen (Advil, Motrin) ne-naproxen (Aleve, Naprosyn); i-digoxin (i-Lanoxin); isisu (‘amaphilisi amanzi’); noma i-insulin noma imithi yomlomo yesifo sikashukela njenge-chlorpropamide (i-Diabinese), i-glimepiride (i-Amaryl, e-Duetact), i-glipizide (i-Glucotrol), i-glyburide (i-DiaBeta, i-Glynase, i-Glucovance), i-tolazamide, ne-tolbutamide. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• utshele udokotela wakho uma uku-dialysis nokuthi unesifo sezinso noma wake waba nesifo sezinso. Udokotela wakho angakutshela ukuthi ungathathi i-empagliflozin.
• utshele udokotela wakho uma uphuza njalo utshwala noma kwesinye isikhathi uphuza utshwala obuningi ngesikhathi esifushane (ukuzitika ngotshwala) noma udla ukudla okune-sodium ephansi. Futhi, tshela udokotela wakho uma ngabe uke waba nezifo zomgudu womchamo noma unezinkinga zokuchama, umfutho wegazi ophansi, i-cholesterol ephezulu, ukwehluleka kwenhliziyo, isifo samanyikwe okubandakanya i-pancreatitis (ukuvuvukala kwamanyikwe) noma uke wahlinzwa amanyikwe, imvubelo izifo endaweni yesitho sangasese, noma isifo sesibindi. Uma ungowesilisa, tshela udokotela wakho uma ungakaze usokwe. Tshela udokotela wakho uma udla kancane ngenxa yokugula, ukuhlinzwa, noma ushintsho ekudleni kwakho noma uma ungakwazi ukudla noma ukuphuza ngokwejwayelekile ngenxa yesicanucanu, ukuhlanza, isifo sohudo, noma uma uphelelwe amanzi emzimbeni ngenxa yokuba selangeni isikhathi eside .
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Ungancelisi ibele ngenkathi uthatha i-empagliflozin. Uma ukhulelwa ngenkathi uthatha i-empagliflozin, shayela udokotela wakho.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi uthatha i-empagliflozin.
• utshwala bungadala ushintsho kushukela wegazi. Buza udokotela wakho mayelana nokusetshenziswa okuphephile kweziphuzo ezidakayo ngenkathi uthatha i-canagliflozin.
• kufanele wazi ukuthi i-empagliflozin ingadala isiyezi, ikhanda elikhanyayo, nokuquleka lapho uvuka ngokushesha okukhulu endaweni yokulala. Uma unale nkinga, shayela udokotela wakho. Le nkinga ivame kakhulu lapho uqala ukuthatha i-empagliflozin. Ukugwema le nkinga, phuma embhedeni kancane, uphumule izinyawo phansi imizuzu embalwa ngaphambi kokuma
• buza udokotela wakho ukuthi yini okufanele uyenze uma ugula, uba nesifo noma umkhuhlane, uba nengcindezi engajwayelekile, noma ulimele. Lezi zimo zingathinta ushukela wegazi lakho kanye nenani le-empagliflozin ongayidinga.

Qiniseka ukuthi ulandela zonke izincomo zokuzivocavoca nezokudla ezenziwa ngudokotela wakho noma udokotela odlayo. Kubalulekile ukudla ukudla okunempilo nokuvivinya umzimba njalo. Landela imiyalo kadokotela wakho mayelana nokuphuza uketshezi olwanele usuku lonke ngenkathi ukule mithi.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

Lo muthi ungadala ushintsho kushukela wakho wegazi. Kufanele wazi izimpawu zikashukela wegazi ophansi futhi ophakeme nokuthi yini okufanele uyenze uma unalezi zimpawu.

I-Empagliflozin ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ukuchama kakhulu, kufaka phakathi nasebusuku
• ukoma okwandisiwe

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

• ukuchama njalo, okuphuthumayo, okushisayo, noma okubuhlungu
• umchamo onamafu, obomvu, opinki, noma onsundu
• ubuhlungu be-pelvic noma be-back
• (kwabesifazane) iphunga lesitho sangasese sowesifazane, ukuphuma okumhlophe noma okuphuzi kwesitho sangasese sowesifazane (kungaba nesigaxa noma kubukeke njenge-cottage shizi), noma ukulunywa kwesitho sangasese sowesifazane
• (emadodeni) ububomvu, ukulunywa, noma ukuvuvukala kwenduku; ukuqhuma emthondweni; ukukhishwa okunuka kabi okuvela epeni; noma ubuhlungu esikhunjeni esizungeze ipipi
• ukuzizwa ukhathele, ubuthakathaka, noma ungakhululekile; kanye nomkhuhlane nobuhlungu, isisa, ubomvu, nokuvuvukala kwezitho zangasese noma indawo ephakathi kwezitho zangasese kanye nengxenyeni
• izimpawu ezinjengomkhuhlane

Uma uhlangabezana nalezi zimpawu ezilandelayo, yeka ukuthatha i-empagliflozin bese ushayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukuqubuka
• isifuba
• ukulunywa
• ubunzima bokugwinya noma ukuphefumula
• ukuvuvukala kobuso, umphimbo, ulimi, izindebe, umlomo, noma amehlo
• ukushaqeka

Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo ze-ketoacidosis, yeka ukuthatha i-empagliflozin bese ushayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo. Uma kunokwenzeka, hlola ama-ketone emchameni wakho uma unalezi zimpawu, noma ngabe ushukela wegazi lakho ungaphansi kuka-250 mg / dL:

• isicanucanu
• ukuhlanza
• ubuhlungu bendawo esiswini
• ukukhathala
• ukuphefumula kanzima

I-Empagliflozin ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Izinga likashukela egazini lakho kufanele lihlolwe njalo ukuthola impendulo yakho ku-empagliflozin. Udokotela wakho uzo-oda ezinye izivivinyo zelebhu, kufaka phakathi i-hemoglobin ye-glycosylated (HbA1c), ukuze uhlole impendulo yakho ku-empagliflozin. Udokotela wakho uzokutshela nokuthi ungayihlola kanjani impendulo yakho kulo muthi ngokulinganisa amazinga kashukela egazini lakho ekhaya. Landela le miyalo ngokucophelela.

Ngaphambi kokwenza noma yiluphi uvivinyo lwelabhoratri, tshela udokotela wakho kanye nabasebenzi belebhuthi ukuthi uthatha impagliflozin. Ngenxa yendlela osebenza ngayo lo muthi, umchamo wakho ungahlola ukuthi une-glucose.

Kufanele njalo ufake isongo lokuhlonza isifo sikashukela ukuze uqiniseke ukuthi uthola ukwelashwa okufanele esimeni esiphuthumayo.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Jardiance^®
• UGlyxambi^® (njengomkhiqizo ohlanganisiwe oqukethe i-Empagliflozin neLinagliptin)
• Okufanayo^® (njengomkhiqizo ohlanganisiwe oqukethe i-Empagliflozin neMetformin)