Vorapaxar

-Delile

• Ngaphambi kokuthatha i-vorapaxar,
• IVorapaxar ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

IVorapaxar ingadala ukopha okukhulu okungasongela impilo futhi kubangele nokufa. Tshela udokotela wakho uma uke wahlaselwa isifo sohlangothi noma waba nesifo sohlangothi esincane; ukopha ebuchosheni; noma yiluphi uhlobo lwegazi noma ukuphazamiseka kokopha; noma isilonda esiswini. Udokotela wakho mhlawumbe uzokutshela ukuthi ungathathi i-vorapaxar. Phinda utshele udokotela wakho uma njengamanje unanoma yiluphi uhlobo lokopha olungavamile njengokuphuma kwegazi ekhanda, esiswini noma emathunjini; uma uke wahlinzwa noma walimala muva nje; noma unesifo sezinso noma sesibindi. Tshela udokotela kanye nosokhemisi wakho uma usebenzisa i-anagrelide (Agrylin); izidakamizwa ezingezona ukuvuvukala (ama-NSAID) ezinjenge-ibuprofen (Advil, Motrin, abanye), indomethacin (Indocin, Tivorbex), ketoprofen, ne-naproxen (i-Aleve, i-Anaprox, ezinye) ezithathwa njalo; dabigatran (Pradaxa); i-dalteparin (Fragmin); i-enoxaparin (i-Lovenox); i-fondaparinux (i-Arixtra); i-heparin; i-Rivaroxaban powder (i-Xarelto); i-serotonin reuptake inhibitors ekhethiwe (SSRIs) efana ne-citalopram (Celexa), i-fluoxetine (i-Prozac, i-Sarafem), i-fluvoxamine (i-Luvox), i-paroxetine (i-Brisdelle, i-Paxil), ne-sertraline (i-Zoloft); kanye ne-serotonin ne-norepinephrine reuptake inhibitors (SNRIs) efana ne-duloxetine (Cymbalta), desvenlafaxine (Khedezla, Pristiq), milnacipran (Fetzima, Savella), ne-venlafaxine (Effexor); kanye ne-warfarin (Coumadin, Jantoven). Uma uhlangabezana nalezi zimpawu ezilandelayo ngesikhathi sokwelashwa kwakho futhi okungenani amasonto ama-4 ngemuva kokuyeka ukuthatha umuthi, shayela udokotela wakho ngokushesha: ukopha okungalindelekile, okunzima, noma ongakwazi ukukulawula; umchamo obomvana, obomvu, noma onsundu; ukuhlanza igazi noma okokusebenza okubukeka njengezizathu zekhofi; izitulo ezibomvu noma ezilindile ezimnyama; ukukhwehlela igazi noma amahlule egazi; ukuphuma kwamakhala; ikhanda; isiyezi; noma ubuthakathaka.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa nge-vorapaxar futhi isikhathi ngasinye lapho ugcwalisa umuthi wakho. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) noma iwebhusayithi yomkhiqizi ukuthola i-Medication Guide.

Khuluma nodokotela wakho ngezingozi zokuthatha i-vorapaxar.

I-Vorapaxar isetshenziswa kanye neminye imishanguzo, njenge-aspirin ne-clopidogrel (i-Plavix), ukunciphisa ubungozi bezinkinga zenhliziyo noma ezisongela impilo noma imithambo yegazi efana nokuhlaselwa yinhliziyo nokushaywa unhlangothi kubantu asebeke bahlaselwa yinhliziyo noma banezinkinga ngokugeleza kwegazi emilenzeni yabo. IVorapaxar isekilasini lemithi ebizwa ngokuthi yi-protease-activated receptor-1 (PAR-1) antagonists. Isebenza ngokuvimbela ama-platelet (uhlobo lweseli legazi) ekuqoqeni nasekwenzeni amahlule angadala isifo senhliziyo noma isifo sohlangothi.

IVorapaxar iza njengethebhulethi ezothathwa ngomlomo. Imvamisa kuthathwa nokudla noma ngaphandle kokudla kanye ngosuku. Thatha i-vorapaxar ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-vorapaxar njengoba iqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

IVorapaxar izonciphisa ubungozi bokuhlaselwa yisifo senhliziyo noma isifo sohlangothi inqobo nje uma uqhubeka nokuphuza umuthi. Ungayeki ukuthatha i-vorapaxar ngaphandle kokukhuluma nodokotela wakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-vorapaxar,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-vorapaxar, noma imiphi eminye imithi, noma iziphi izithako ezikumaphilisi e-vorapaxar. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, kanye nezithako zokudla okunomsoco ozithathayo noma ohlela ukuzithatha. Qiniseka ukuthi uyayisho imishanguzo ebhalwe esigabeni ESIBALULEKILE SESEXWAYISO nanoma yikuphi okulandelayo: ama-antifungal athile afana ne-itraconazole (Sporanox, Onmel), ketoconazole (Nizoral), ne-posaconazole (Noxafil); i-boceprevir (i-Victrelis); carbamazepine (Carbatrol, Tegretol); i-clarithromycin (i-Biaxin, ku-PrevPac); i-conivaptan (iVaprisol); imishanguzo ethile yegciwane lengculazi (i-HIV) njenge-indinavir (Crixivan), i-nelfinavir (i-Viracept), i-ritonavir (i-Norvir, e-Kaletra), ne-saquinavir (i-Invirase); nefazodone; i-phenytoin (iDilantin, Phenytek); i-rifampin (i-Rifadin, i-Rimactane); iTelaprevir (Incivek); kanye ne-telithromycin (Ketek); Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• utshele udokotela wakho ukuthi yimiphi imikhiqizo yamakhambi oyithathayo, ikakhulukazi iSt Johns wort.
• Tshela udokotela wakho uma uke waba nanoma yisiphi isimo sezokwelapha noma ikakhulukazi esisohlwini lwengxenye EBALULEKILE YESEXWAYISO.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha i-vorapaxar, shayela udokotela wakho.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi uthatha i-vorapaxar.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

IVorapaxar ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ukukhathala
• ubuthakathaka
• isikhumba esiphaphathekile
• izandla nezinyawo ezipholile

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi izimpawu ezibhalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo.

IVorapaxar ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese). Ungayikhiphi i-desiccant (i-agent eyomisa) ebhodleleni, uma inikiwe.

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Ubuhle^®