Inaliti yeSecukinumab

-Delile

• Ngaphambi kokusebenzisa umjovo we-secukinumab,
• Umjovo weSecukinumab ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu noma lezo ezisohlwini lwe-SPECIAL PRECAUTIONS section, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

Umjovo weSecukinumab usetshenziselwa ukwelapha i-plaque psoriasis elinganiselayo (isifo sesikhumba lapho kwakhiwa khona amabala abomvu, anezikhala kwezinye izindawo zomzimba) kubantu abadala abane-psoriasis enzima kakhulu ukuthi ingalashwa yimithi yokwelapha kuphela. Ibuye isetshenziselwe abantu abadala ukwelapha i-psoriatic arthritis (isimo esidala ubuhlungu bamalunga nokuvuvukala nezikali esikhunjeni). Umjovo weSecukinumab usetshenziswa kubantu abadala ukwelapha i-ankylosing spondylitis (isimo lapho umzimba uhlasela khona amalunga omgogodla nezinye izindawo, okudala ubuhlungu, ukuvuvukala nokulimala ngokuhlanganyela). Ibuye isetshenziselwe abantu abadala ukwelapha i-axial spondyloarthritis (i-axial spondyloarthritis) esebenzayo (isimo lapho umzimba uhlasela khona amalunga omgogodla nezinye izindawo, okudala ubuhlungu nezimpawu zokuvuvukala, kepha ngaphandle kwezinguquko ezibonakala kwi-x-ray). Umjovo weSecukinumab usesigabeni semithi ebizwa ngama-antibody monoclonal. Isebenza ngokumisa ukusebenza kwamaseli athile emzimbeni adala izimpawu ze-psoriasis.

Umjovo weSecukinumab uza njengesirinji ekhethiwe, ipeni lokulinganisa, nanjengempuphu ezohlanganiswa noketshezi bese ujovwa ngomgogodla (ngaphansi kwesikhumba). Kuvamise ukujova kanye njalo lapho kutholwa imithamo emihlanu yokuqala bese kuba kanye njalo emavikini amane. I-psoriatic arthritis, i-ankylosing spondylitis, ne-axial spondyloarthritis, ingahle ijojowe kanye njalo emavikini amane. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Sebenzisa umjovo we-secukinumab njengoba uqondisiwe. Ungayifaki ngaphezulu noma ngaphansi kwayo noma uyijoje kaningi kunokuyalelwa ngudokotela wakho.

Ungathola umthamo wakho wokuqala ongaphansi komjovo we-secukinumab ehhovisi likadokotela wakho. Ngemuva kwalokho, udokotela wakho angakuvumela ukuthi ujove i-secukinumab ngokwakho noma ube nomngane noma isihlobo esenza imijovo. Ngaphambi kokusebenzisa umjovo we-secukinumab ngokwakho okokuqala, funda imininingwane yomkhiqizi yesiguli esiza nomuthi. Buza udokotela wakho noma usokhemisi ukuthi akubonise noma umuntu ozobe ejova umuthi ukuthi ungawujova kanjani.

Sebenzisa isipetu noma ipeni ngalinye kanye bese ufaka yonke ikhambi esirinji noma epeni. Lahla imijovo nezibaya ezisetshenzisiwe esitsheni esingamelana nokubhoboza. Khuluma nodokotela wakho noma usokhemisi mayelana nokuthi ungasilahla kanjani isitsha esingamelana nokubhoboza.

Uma usebenzisa isirinji oyithandayo noma ipeni lomthamo elifakwe esiqandisini, beka isirinji noma ipeni endaweni eyisicaba ngaphandle kokukhipha ikepisi lenaliti bese uyivumela ifudumele ekamelweni lokushisa imizuzu eyi-15-30 ngaphambi kokuba ulungele ukujova umuthi . Ungazami ukufudumeza umuthi ngokuwufudumeza ngemicrowave, uwubeke emanzini ashisayo, noma ngenye indlela. Sebenzisa umjovo okungenani ihora elilodwa ngemuva kokukhipha esiqandisini.

Unganyakazisi isirinji noma ipeni le-dosing eliqukethe i-secukinumab.

Njalo bheka isisombululo se-secukinumab ngaphambi kokusijova. Hlola ukuthi usuku lokuphelelwa yisikhathi aludlulanga nokuthi uketshezi lucacile futhi alunambala. Uketshezi akufanele luqukethe izinhlayiya ezibonakalayo. Ungasebenzisi isirinji noma ipeni lokufaka imithamo uma iqhekekile noma yephukile, uma iphelelwe yisikhathi, noma uma uketshezi luguqubele noma luqukethe izinhlayiya ezinkulu noma ezinemibala.

Ungajova umjovo we-secukinumab noma yikuphi ngaphambili kwamathanga akho (umlenze ongaphezulu), izingalo ezingaphezulu, noma isisu (isisu) ngaphandle kwenkaba yakho nendawo engamasentimitha ama-5 ukuyizungeza. Ukwehlisa amathuba okuba buhlungu noma okubomvu, sebenzisa isiza esihlukile ngomjovo ngamunye. Ungafaki endaweni lapho isikhumba sithambile, silimele, sibomvu, noma siqinile noma lapho unezibazi noma izimpawu zokwelula.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa ngomjovo we-secukinumab. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokusebenzisa umjovo we-secukinumab,

• Tshela udokotela kanye nosokhemisi wakho uma uneguliswa umjovo we-secukinumab, noma imuphi omunye umuthi, i-latex, noma ezinye izithako zomjovo we-secukinumab. Buza usokhemisi wakho ukuthola uhlu lwezithako. Uma uzosebenzisa isipontsho noma ipeni yokufaka, oyithandayo, tshela udokotela wakho uma wena noma umuntu ozokujolela umuthi uzwela i-raber noma i-latex.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma ikuphi kokulandelayo: ama-anticoagulants (ama-thinner egazi) njenge-warfarin (i-Coumadin, i-Jantoven) nemithi ecindezela amasosha omzimba njenge-cyclosporine (Gengraf, Neoral, Sandimmune). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• utshele udokotela wakho uma uke waba nesifo sikaCrohn noma (wake waba nesimo lapho umzimba uhlasela ulwelwesi lomgudu wokugaya ukudla, ubangele ubuhlungu, isifo sohudo, ukuncipha komzimba nomkhuhlane) noma yiziphi ezinye izimo zezokwelapha.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi usebenzisa umjovo we-secukinumab, shayela udokotela wakho.
• thintana nodokotela wakho ukuze ubone uma ngabe udinga ukuthola noma yimiphi imigomo. Kubalulekile ukuthi ube nayo yonke imigomo efanele iminyaka yakho ngaphambi kokuqala ukwelashwa kwakho ngomjovo we-secukinumab. Ungabi nayo imigomo ngesikhathi sokwelashwa kwakho ngaphandle kokukhuluma nodokotela wakho.
• kufanele wazi ukuthi umjovo we-secukinumab unganciphisa ikhono lakho lokulwa nokutheleleka kusuka kubhaktheriya, amagciwane, nesikhunta futhi kwandise ingozi yokuthi uzothola ukutheleleka okungathi sína noma okusongela ukuphila. Tshela udokotela wakho uma uvame ukuthola noma yiluphi uhlobo lokutheleleka noma uma une noma ucabanga ukuthi ungahle ube nolunye uhlobo lokutheleleka manje. Lokhu kufaka ukutheleleka okuncane (njengokusikeka okuvulekile noma izilonda), izifo ezifika zidlule (njenge-herpes noma izilonda ezibandayo), kanye nezifo ezingapheli ezingapheli. Uma uhlangabezana nalezi zimpawu ezilandelayo ngesikhathi noma ngemuva nje kokwelapha kwakho ngomjovo we-secukinumab, shayela udokotela wakho ngokushesha: umkhuhlane, ukujuluka, noma ukubanda, izinhlungu zemisipha, ukuphefumula okuncane, ukufudumala, okubomvu, noma isikhumba esibuhlungu noma izilonda emzimbeni wakho, uhudo, ubuhlungu besisu, ukuchama kaningi, okuphuthumayo noma okubuhlungu, noma ezinye izimpawu zokutheleleka.
• kufanele wazi ukuthi ukusebenzisa umjovo we-secukinumab kwandisa ubungozi bokuthi uzoba nesifo sofuba (i-TB; isifo esibucayi samaphaphu), ikakhulukazi uma usuvele ungenwe yisifo sofuba kodwa ungenazo izimpawu zesifo. Tshela udokotela wakho uma uke waba ne-TB noma wake waba nayo, uma ngabe uhlala ezweni lapho i-TB ijwayelekile khona, noma uma wake waba seduze komuntu one-TB. Udokotela wakho uzokuhlolela isikhumba ukuze abone ukuthi une-TB engasebenzi yini. Uma kunesidingo, udokotela wakho uzokunika imithi yokwelapha lesi sifo ngaphambi kokuqala ukusebenzisa umjovo we-secukinumab. Uma unezinye zalezi zimpawu ezilandelayo ze-TB, noma uma uba nalezi zimpawu phakathi nokwelashwa kwakho, shayela udokotela wakho ngokushesha: ukukhwehlela, ukukhwehlela igazi noma amafinyila, ubuthakathaka noma ukukhathala, ukuncipha komzimba, ukulahlekelwa isifiso sokudla, ukugodola, umkhuhlane , noma ukujuluka ebusuku.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Shayela udokotela wakho akubuze ukuthi wenzeni uma uphuthelwa umthamo womjovo we-secukinumab. Ungasebenzisi umthamo ophindwe kabili ukwenza okulahlekile.

Umjovo weSecukinumab ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ukugijima, ikhala eligxishiwe, ukuthimula
• Umphimbo obuhlungu
• ukulunywa

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu noma lezo ezisohlwini lwe-SPECIAL PRECAUTIONS section, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukuqubuka
• isifuba
• ukuphefumula kanzima noma ukugwinya
• ngizizwe ngiphela amandla
• ukuvuvukala kwamehlo, ubuso, izindebe, ulimi, umphimbo
• ukuqina kwesifuba
• ukushaqeka

Umjovo weSecukinumab ungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthola lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina umjovo we-secukinumab esiqandisini kodwa ungafrizi. Gcina izitsha, isirinji ekhethiwe, nezibaya zokufaka umthamo emabhokisini azo okuqala ukuze zivikele ekukhanyeni.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho.

Ungavumeli omunye umuntu asebenzise imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Buza usokhemisi wakho noma imiphi imibuzo onayo ngomjovo we-secukinumab.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

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