Isavuconazonium Injection

-Delile

• Ngaphambi kokuthola umjovo we-isavuconazonium,
• Umjovo we-Isavuconazonium ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

Umjovo we-Isavuconazonium usetshenziselwa ukwelapha ukutheleleka okunzima okufana ne-aspergillosis (isifo esikhunta esiqala emaphashini bese sisakazeka egazini liye kwezinye izitho) kanye ne-mucormycosis (isifo sokukhunta esivame ukuqala ezonweni, ebuchosheni noma emaphashini) . Umjovo we-Isavuconazonium usesigabeni semithi ebizwa ngama-azole antifungals. Isebenza ngokunciphisa ukukhula kwesikhunta okubangela ukutheleleka.

Umjovo we-Isavuconazonium uza njengempuphu ezohlanganiswa noketshezi bese ujovwa ngomjovo (emthanjeni). Imvamisa inikezwa okungenani ihora elilodwa njalo emahoreni ayi-8 emithamo yokuqala eyisithupha bese kanye kanye ngosuku. Ubude bokwelashwa kwakho buncike empilweni yakho ejwayelekile, uhlobo lokutheleleka onalo, nokuthi uphendula kahle kangakanani emithini. Ungathola umjovo we-isavuconazonium esibhedlela noma ungahlinzeka ngemithi ekhaya. Uma uzokwamukela umjovo we-isavuconazonium ekhaya, umhlinzeki wakho wokunakekelwa kwezempilo uzokukhombisa ukuthi uwusebenzisa kanjani umuthi. Qiniseka ukuthi uyaziqonda lezi zinkomba, bese ubuza umhlinzeki wakho wezokunakekelwa kwezempilo uma unemibuzo.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola umjovo we-isavuconazonium,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-isavuconazonium, i-fluconazole, i-itraconazole, i-ketoconazole, i-posaconazole, i-voriconazole, noma imiphi eminye imithi, noma iziphi izithako zomjovo we-isavuconazonium. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho uma uthatha i-carbamazepine (Carbatrol, Tegretol), ketoconazole (Nizoral), phenobarbital, rifampin (Rifadin, Rifamate), ritonavir (Norvir, in Kaletra), noma iSt John's wort. Udokotela wakho uzokutshela ukuthi ungasebenzisi umjovo we-isavuconazonium uma uthatha eyodwa noma ngaphezulu yale mithi.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma ikuphi kokulandelayo: ), i-sirolimus (i-Rapamune), noma i-tacrolimus (i-Prograf). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo eminingi ingaxhumana ne-isavuconazonium, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho nalawo angaveli kulolu hlu.
• Tshela udokotela wakho uma wena noma omunye emndenini wakho enesifo esifushane se-QT (isimo esandisa ubungozi bokushaya kwenhliziyo okungajwayelekile, isiyezi, ukuquleka noma ukufa ngokuzuma). Udokotela wakho mhlawumbe uzokutshela ukuthi ungatholi umjovo we-isavuconazonium.
• utshele udokotela wakho uma uke waba nezinkinga zenhliziyo noma zesibindi noma wake waba nazo.
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthola umjovo we-isavuconazonium, shayela udokotela wakho.

Khuluma nodokotela wakho ngokudla isithelo samagilebhisi nokuphuza ijusi lamagilebhisi ngenkathi uthola lo muthi.

Umjovo we-Isavuconazonium ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isifo sohudo
• ukuqunjelwa
• ikhanda
• ukuhlungu obusemhlane
• ukukhwehlela
• ubunzima bokulala noma ukulala
• ukukhathazeka
• ukuyaluza
• ukudideka
• ukuncipha kokudla

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• isifuba
• ukuqubuka
• ukulunywa
• isikhumba esihlabayo noma esishayayo
• isicanucanu
• ukuhlanza
• ukuphuzi kwesikhumba noma kwamehlo
• ukukhathala ngokweqile
• izimpawu ezinjengomkhuhlane
• ubuhlungu bemisipha, amajaqamba, noma ubuthakathaka
• ukushaya kwenhliziyo okungajwayelekile
• ukuvuvukala kwezandla, izinyawo, izingalo noma imilenze
• ukuphefumula kanzima noma ukugwinya
• ukuquleka
• ukungaboni kahle
• isiyezi
• Ukugodola
• ukuba ndikindiki, ukushiswa, noma ukuncinza ezandleni, ezingalweni, ezinyaweni noma emilenzeni
• ushintsho kumuzwa wakho wokuthinta

Umjovo we-Isavuconazonium ungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthola lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• ikhanda
• isiyezi
• ubuhlungu, ukushisa, noma ukuncinza ezandleni noma ezinyaweni
• ukozela
• ubunzima bokugxila
• shintsha ngomqondo wokunambitha
• umlomo owomile
• ukuba ndikindiki emlonyeni
• isifo sohudo
• ukuhlanza
• ukubomvu ngokungazelelwe kobuso, intamo, noma isifuba esingenhla
• ukukhathazeka
• ukungahlaliseki
• ukushaya ngamandla noma ukushaya kwenhliziyo okusheshayo
• ukuzwela kweso ekukhanyeni
• ubuhlungu obuhlangene

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho angalawula izivivinyo ezithile zebhu ukuze ahlole impendulo yomzimba wakho kumjovo we-isavuconazonium.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• UCremba^® I.V.