Inaliti ye-Aripiprazole

-Delile

• Ngaphambi kokuthola umjovo okhipha isikhathi eside we-aripiprazole,
• Umjovo wokukhishwa kwe-Aripiprazole enwetshiwe ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe ezigabeni EZIBALULEKILE ZESEXWAYISO noma ZOKUQAPHA, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

Ucwaningo lukhombisile ukuthi abantu abadala asebekhulile abanenkinga yokuwohloka komqondo (ukuphazamiseka ebuchosheni okuthinta amandla okukhumbula, ukucabanga kahle, ukuxhumana, nokwenza imisebenzi yansuku zonke futhi lokho kungadala ushintsho esimweni sengqondo nobuntu) abathatha noma bathole ama-antipsychotic (imithi yokugula ngengqondo) njengoba i-aripiprazole inamathuba amaningi okufa ngesikhathi sokwelashwa. Abantu abadala asebekhulile abanenkinga yokuwohloka komqondo futhi bangaba nethuba elikhulu lokuba nesifo sohlangothi noma i-ministroke ngenkathi belashwa ngama-antipsychotic.

Umjovo we-Aripiprazole enwetshiwe (osebenza isikhathi eside) awuvunyelwe yi-Food and Drug Administration (FDA) ekwelapheni ukuphazamiseka kokuziphatha kubantu abadala asebekhulile abanenkinga yokuwohloka komqondo. Khuluma nodokotela onikeze lo muthi uma wena, ilungu lomndeni, noma umuntu omnakekelayo enesifo sokuwohloka komqondo futhi ethola i-aripiprazole. Ngeminye imininingwane vakashela iwebhusayithi ye-FDA: http://www.fda.gov/Drugs.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa ngomjovo wokukhishwa okwandisiwe we-aripiprazole futhi isikhathi ngasinye lapho uthola umjovo. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) noma iwebhusayithi yomkhiqizi ukuthola i-Medication Guide.

Khuluma nodokotela wakho ngezingozi zokuthola umjovo wokukhipha i-aripiprazole enwetshiwe.

Umjovo wokukhishwa kwe-Aripiprazole enwetshiwe (Abilify Maintena, Aristada, Aristada Initio) usetshenziswa wedwa noma uhlanganiswe namanye amalungiselelo e-aripiprazole ukwelapha i-schizophrenia (ukugula kwengqondo okubangela ukucabanga okuphazamisayo noma okungajwayelekile, ukulahlekelwa yintshisekelo empilweni, nemizwelo eqinile noma engafanele) . Umjovo wokukhishwa kwe-Aripiprazole enwetshiwe (Abilify Maintena) nawo usetshenziselwa ukwelashwa okuqhubekayo kwabantu abane-bipolar I disorder (i-manic-depress disorder; isifo esibanga iziqephu zokudangala, iziqephu ze-mania, nezinye izimo ezingavamile). I-Aripiprazole isekilasini lemithi ebizwa nge-atypical antipsychotic. Isebenza ngokushintsha ukusebenza kwezinto ezithile zemvelo ebuchosheni.

Umjovo wokukhishwa kwe-Aripiprazole enwetshiwe uza njengempuphu ezoxutshwa namanzi (Abilify Maintena) nanjengokumiswa (uketshezi) (i-Aristada, i-Aristada Initio) ezofakwa emsipheni ngumhlinzeki wezokunakekelwa kwempilo.

Umjovo wokukhipha i-Aripiprazole enwetshiwe (Abilify Maintena) uvame ukunikezwa kanye njalo emavikini amane. Uma ungakaze uthole i-aripiprazole phambilini, udokotela wakho uzokutshela ukuthi uphuze amaphilisi e-aripiprazole ngomlomo kuze kube amasonto amabili ngaphambi kokuthola umjovo wakho wokuqala. Kuzodingeka futhi ukuthi uphuze amaphilisi e-aripiprazole noma omunye umuthi wokuqeda imishanguzo ngomlomo emasontweni amabili okuqala ngemuva nje kokuthola umjovo wakho wokuqala womjovo wokukhishwa oweluliwe we-aripiprazole (Abilify Maintena).

Umjovo wokukhipha i-Aripiprazole enwetshiwe (i-Aristada) uvame ukunikezwa kanye njalo emavikini ayi-4, 6 noma ama-8. Uma ungakaze uthole i-aripiprazole phambilini, udokotela wakho uzokutshela ukuthi uphuze amaphilisi e-aripiprazole ngomlomo kuze kube amasonto amabili ngaphambi kokuthola umjovo wakho wokuqala. Kuzodingeka futhi ukuthi uphuze amaphilisi e-aripiprazole noma omunye umuthi we-antipsychotic ngomlomo emasontweni amabili okuqala ngemuva kokuthola umjovo wakho wokuqala we-aripiprazole injection-release injection (Aristada). Ngenye indlela, ungathola imithamo yesikhathi esisodwa yomjovo we-aripiprazole enwetshiwe (i-Aristada Initio) nethebhulethi eyodwa ye-aripiprazole ngomlomo lapho uqala ukwelashwa ngomjovo wokukhipha i-aripiprazole (Aristada).

Umjovo wokukhishwa kwe-Aripiprazole enwetshiwe ungasiza ekulawuleni izimpawu zakho kepha ngeke uselaphe isimo sakho. Qhubeka nokugcina ama-aphoyintimenti ukuthola umjovo wokukhipha i-aripiprazole noma ngabe uzizwa uphilile. Khuluma nodokotela wakho uma ungazizwa sengathi uba ngcono ngesikhathi sokwelashwa kwakho ngomjovo wokukhishwa okwandisiwe we-aripiprazole.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola umjovo okhipha isikhathi eside we-aripiprazole,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-aripiprazole, noma imuphi omunye umuthi, noma iziphi izithako zomjovo wokukhipha i-aripiprazole enwetshiwe. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: carbamazepine (Carbatrol, Epitol, Tegretol); i-clarithromycin (i-Biaxin, ku-Prevpac); i-fluoxetine (Prozac, Sarafem, Symbyax); itraconazole (Onmel, Sporanox); ketoconazole; i-lorazepam (i-Ativan); imishanguzo ethile yokulawula umfutho wegazi ophezulu njenge-carvedilol (Coreg), lisinopril (Qbrelis, Zestril), prazosin (Minipress); i-quinidine (ku-Nuedexta); kanye ne-rifampin (Rifadin, Rimactane, eRifamate, eRifater). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo eminingi ingaxhumana ne-aripiprazole, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu.
• utshele udokotela wakho uma uhudo olunzima noma uhlanza noma ucabanga ukuthi kungenzeka uphelelwe amanzi emzimbeni. Tshela nodokotela wakho uma uke waba nesifo senhliziyo, ukuhluleka kwenhliziyo, isifo senhliziyo, ukushaya kwenhliziyo okungajwayelekile, umfutho wegazi ophakeme noma ophansi, isifo sohlangothi, i-ministroke, isithuthwane, inani eliphansi lamaseli amhlophe egazi, i-dyslipidemia (ephezulu amazinga e-cholesterol), unenkinga yokugcina ibhalansi yakho, noma yisiphi isimo esenza kube nzima ukuthi usigwinye. Tshela udokotela wakho uma wena noma omunye emndenini wakho usebenzisa noma usebenzise izidakamizwa zasemgwaqeni noma usebenzise ngokweqile imithi kadokotela noma uphuzo oludakayo noma uke waba nesifo sikashukela, isifo sokucindezela ngokweqile, ukuphazamiseka kokulawula umfutho, ukuphazamiseka kwengqondo okuguquguqukayo, noma ubuntu bokuxhamazela. Phinda utshele udokotela wakho uma wake wakuyeka ukuthatha umuthi wokugula ngengqondo ngenxa yemiphumela emibi kakhulu.
• tshela udokotela wakho uma ukhulelwe, ikakhulukazi uma usezinyangeni ezimbalwa ezedlule zokukhulelwa kwakho, uma uhlela ukukhulelwa, noma uma uncelisa. Uma ukhulelwa ngesikhathi sokwelashwa kwakho nge-aripiprazole, shayela udokotela wakho.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi welashwa nge-aripiprazole.
• kufanele wazi ukuthi ukuthola umjovo wokukhishwa kwe-aripiprazole enwetshiwe kungakwenza ukozele futhi kungathinta ikhono lakho lokucabanga kahle, wenze izinqumo, futhi usabele ngokushesha. Ungashayeli imoto noma usebenzise imishini uze wazi ukuthi lo muthi ukuthinta kanjani.
• kufanele wazi ukuthi utshwala bungangezela ukozela okubangelwa yilomuthi. Ungaphuzi utshwala ngesikhathi sokwelashwa kwakho nge-aripiprazole.
• kufanele wazi ukuthi umjovo wokukhishwa kwe-aripiprazole enwetshiwe ungadala isiyezi, ikhanda elikhanyayo, ukushaya kwenhliziyo okusheshayo noma okuhamba kancane, nokuquleka lapho uvuka masinyane usuka endaweni elele, ikakhulukazi ngemuva nje kokuthola umjovo wakho. Uma uzizwa unesiyezi noma ukozela ngemuva kokuthola umjovo wakho, kuzodingeka ulale phansi uze uzizwe ungcono. Ngesikhathi sokwelashwa kwakho, kufanele uvuke embhedeni kancane, uphumule izinyawo zakho phansi imizuzu embalwa ngaphambi kokuma.
• kufanele wazi ukuthi ungathola i-hyperglycemia (inyuka kushukela egazini lakho) ngenkathi uthola lo muthi, noma ngabe awunaso vele isifo sikashukela. Uma une-schizophrenia, kungenzeka ukuthi ube nesifo sikashukela kunabantu abangenayo i-schizophrenia, futhi ukuthola umjovo wokukhishwa okwandisiwe we-aripiprazole noma imishanguzo efanayo kungandisa le ngozi. Tshela udokotela wakho ngokushesha uma unalezi zimpawu ezilandelayo ngesikhathi sokwelashwa kwakho: ukoma ngokweqile, ukuchama kaningi, ukulamba ngokweqile, ukungaboni kahle, noma ubuthakathaka. Kubaluleke kakhulu ukubiza udokotela wakho ngokushesha uma unezinye zalezi zimpawu, ngoba ushukela ophakeme wegazi ungadala isimo esibi esibizwa nge-ketoacidosis. I-Ketoacidosis ingasongela impilo uma ingelashwa kusenesikhathi. Izimpawu ze-ketoacidosis zifaka phakathi umlomo owomile, isicanucanu nokuhlanza, ukuphefumula okuncane, ukuphefumula okunuka izithelo, nokuncipha kokwazi.
• kufanele wazi ukuthi abanye abantu abasebenzisa imishanguzo efana ne-aripiprazole injection-release injection baba nezinkinga zokugembula noma ezinye izifiso ezinamandla noma isimilo ebesibaphoqa noma singavamile kubo, njengokukhuphuka kwezifiso zocansi noma isimilo, ukuthenga ngokweqile, nokuzitika ngotshwala.Shayela udokotela wakho uma unesifiso esikhulu sokuthenga, ukudla, ukuya ocansini, noma ukugembula, noma uma ungakwazi ukulawula ukuziphatha kwakho. Tshela amalungu omndeni wakho ngale ngozi ukuze bakwazi ukubiza udokotela noma ngabe awuboni ukuthi ukugembula kwakho noma yiziphi ezinye izifiso ezinamandla noma ukuziphatha okungajwayelekile kube yinkinga.
• kufanele wazi ukuthi umjovo wokukhipha i-aripiprazole onwetshiwe ungenza kube nzima emzimbeni wakho ukuthi wehlise umoya uma kushisa kakhulu. Tshela udokotela wakho uma uhlela ukuzivocavoca ngamandla noma uvezwe ukushisa okukhulu. Qiniseka ukuthi uphuza amanzi amaningi futhi ushayele udokotela wakho uma uhlangabezana nalezi zimpawu ezilandelayo: uzizwa ushisa kakhulu, ujuluka kakhulu, ungajuluki yize kushisa, umlomo womile, ukoma ngokweqile noma ukwehla kokuchama.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Uma ukhohlwa ukugcina i-aphoyintimenti yokuthola umjovo wokukhishwa okwandisiwe we-aripiprazole (Abilify Maintena, Aristrada), shayela udokotela wakho ukuhlela enye i-aphoyintimenti ngokushesha okukhulu.

Umjovo wokukhishwa kwe-Aripiprazole enwetshiwe ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ubuhlungu, ukuvuvukala, ububomvu endaweni yomjovo
• ukuzuza kwesisindo
• ukwanda kwesifiso sokudla
• ukukhathala ngokweqile
• ubuhlungu besisu
• ukuqunjelwa
• ukuhlanza
• umlomo owomile
• emuva, imisipha, noma ubuhlungu obuhlangene
• ubunzima bokulala noma ukulala
• isiyezi, ukuzizwa ungagxilile, noma unenkinga yokugcina ibhalansi yakho

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe ezigabeni EZIBALULEKILE ZESEXWAYISO noma ZOKUQAPHA, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukuqubuka
• ukulunywa
• isifuba
• ukuvuvukala kobuso, umphimbo, ulimi, izindebe, amehlo, izandla, izinyawo, amaqakala, kanye / noma imilenze engezansi
• ubunzima bokugwinya noma ukuphefumula
• ukuqina kwemisipha
• ukujuluka okweqile
• ukushaya kwenhliziyo okungajwayelekile
• ukudideka
• ukuwa
• ukunyakaza okungajwayelekile kobuso noma komzimba ongeke ukwazi ukukulawula
• ukuzamazama okungalawuleki kwengxenye yomzimba
• ukungahlaliseki
• ngidinga ukusukuma nginyakaze
• ukunyakaza okuhamba kancane
• umphimbo obuhlungu, umkhuhlane, ukubanda, noma ezinye izimpawu zokutheleleka
• isithuthwane

Umjovo wokukhishwa kwe-Aripiprazole enwetshiwe ungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthola lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• ukudideka
• ukudideka
• ukuhlanza
• ukunyakaza okuhamba kancane noma okungalawuleki
• ukozela
• isithuthwane
• isimilo esinolaka
• ikhoma (ukulahlekelwa ukwazi isikhathi esithile)

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho anga-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho kumjovo wokukhishwa okwandisiwe we-aripiprazole.

Buza usokhemisi wakho noma imiphi imibuzo onayo ngomjovo wokukhishwa okwandisiwe we-aripiprazole.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Yenza amandla^®¶
• Hlomulisa uManaena^®
• Aristada^®
• Aristad Initio^®

^¶ Lo mkhiqizo onophawu alusekho emakethe. Ezinye izindlela ezijwayelekile zingatholakala.