I-Rifapentine

-Delile

• Ngaphambi kokuthatha i-rifapentine,
• I-Rifapentine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

I-Rifapentine isetshenziswa neminye imithi yokwelapha isifo sofuba esisebenzayo (i-TB; ukutheleleka okungathi sína okuthinta amaphaphu futhi kwesinye isikhathi nezinye izingxenye zomzimba) kubantu abadala nezingane ezineminyaka engu-12 nangaphezulu. I-Rifapentine ibuye isetshenziswe ne-isoniazid (Laniazid) ukwelapha abantu abadala nezingane ezineminyaka emibili kuya phezulu nge-latent (ukuphumula noma ukungalali) i-TB, kubandakanya nalabo abasondelene kakhulu nabantu abane-TB esebenzayo, ukuhlolwa kwesikhumba se-tuberculin, igciwane lesandulela ngculaza (I-HIV), noma labo abane-pulmonary fibrosis (isibazi samaphaphu ngesizathu esingaziwa). URifapentine usesigabeni semithi ebizwa ngama-antimycobacterials. Isebenza ngokubulala amabhaktheriya abangela ukutheleleka.

Ama-antibiotic afana ne-rifapentine ngeke asebenzele imikhuhlane, umkhuhlane, noma okunye ukutheleleka ngegciwane. Ukusebenzisa ama-antibiotic lapho kungadingeki kwandisa ingozi yakho yokuthola ukutheleleka kamuva okuphikisana nokwelashwa kwama-antibiotic.

IRifapentine iza njengethebhulethi ezothathwa ngomlomo. Lapho i-rifapentine isetshenziselwa ukwelapha i-TB esebenzayo, imvamisa iphuzwa ngokudla kabili ngesonto, ngemithamo okungenani ehlukaniswe izinsuku ezintathu, ezinyangeni ezimbili zokuqala bese kanye kanye ngesonto izinyanga ezine. Lapho i-rifapentine isetshenziselwa ukwelapha ukutheleleka kwe-TB okuqubisile, kufanele kube ngokudla okuphuzwa kanye ngesonto. Thatha i-rifapentine ngasikhathi sinye njalo ngosuku oluhleliwe. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-rifapentine njengoba nje uqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Uma ungakwazi ukugwinya amaphilisi, ungawachoboza bese uxuba umuthi ngesilinganiso esincane sokudla okune-semisolid njenge-pudding noma i-appleauce. Gwinya ingxube ngokushesha; ungayigcini ukuze uyisebenzise kamuva.

Qhubeka uphuze i-rifapentine uze uqede incwadi kadokotela noma ngabe uzizwa ungcono, futhi uqaphele ukuthi ungaphuthelwa imithamo. Uma uyeka ukuthatha i-rifapentine maduzane, ukutheleleka kwakho kungenzeka kungalashwa ngokuphelele futhi amabhaktheriya angamelana nemithi elwa namagciwane. Uma uphuthelwa imithamo ye-rifapentine, ungaqala ukuba nezimpawu ezingathandeki noma ezimbi lapho uqala ukuthatha umuthi futhi.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-rifapentine,

• Tshela udokotela kanye nosokhemisi wakho uma unegciwane ku-rifapentine, i-rifabutin (i-Mycobutin), i-rifampin (i-Rifadin, i-Rimactane, i-Rifamate, i-Rifater), i-rifaximin (i-Xifaxan), noma imuphi omunye umuthi, noma iziphi izithako ezikumaphilisi e-rifapentine. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: imithi elwa namagciwane efana ne-chloramphenicol, i-ciprofloxacin (Cipro), i-clarithromycin (i-Biaxin, e-Prevpac), i-dapsone, ne-doxycycline (i-Doryx, i-Monodox, i-Vibramycin, eminye); ama-anticoagulants (’ama-thinner egazi’) njenge-warfarin (i-Coumadin, i-Jantoven); ama-antifungals afana ne-fluconazole (Diflucan), i-itraconazole (i-Onmel, i-Sporanox), ne-ketoconazole; ama-calcium channel blocker afana ne-diltiazem (Cardizem, Taztia, Tiazac, abanye), nifedipine (Adalat, Afeditab, Procardia), kanye ne-verapamil (Calan, Covera, Verelan); i-clofibrate (i-Atromid-S; ayisatholakali e-U.S.); i-cyclosporine (Gengraf, Neoral, Sandimmune); diazepam (Valium); i-digoxin (i-Lanoxin); i-disopyramide (iNorpace); i-glyburide (i-Diabeta, i-Glynase); i-glipizide (iGlucotrol); i-haloperidol (iHaldol); Imithi ye-HIV; i-levothyroxine (Levoxyl, Synthroid, Tirosint); i-methadone (i-Dolophine, i-Methadose); mexiletine, phenobarbital; i-phenytoin (iDilantin, Phenytek); i-prednisone (iRayos); i-propranolol (IHemangeol, Inderal, InnoPran); i-quinidine (ku-Nuedexta), i-quinine (i-Qualaquin); i-sildenafil (i-Revatio, i-Viagra); tacrolimus (Astagraf, Envarsus, Prograf); i-theophylline (i-Elixophyllin, i-Theochron, i-Uniphyl); i-tocainide (iTonocard; ayisatholakali e-U.S.); kanye ne-tricyclic antidepressants efana ne-amitriptyline ne-nortriptyline (Pamelor). Eminye imithi eminingi ingaxhumana ne-rifapentine, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• Tshela udokotela wakho uma uthatha noma usebenzisa izinto zokuvimbela inzalo ze-hormonal (amaphilisi okulawula ukubeletha, amabala, izindandatho, okufakelwa kanye nemijovo). I-Rifapentine inganciphisa ukusebenza kahle kokuvimbela inzalo ngama-hormonal. Kufanele usebenzise enye indlela yokulawula ukubeletha ngenkathi usebenzisa le mithi. Khuluma nodokotela wakho mayelana nokulawulwa kokuzalwa ngenkathi uthatha i-rifapentine.
• Tshela udokotela wakho uma une-TB esebenzayo noma ubungaphenduli kweminye imishanguzo ye-TB noma uma uke waba ne-porphyria (noma lapho uke waba ne-porphyria (isimo lapho izinto ezithile zemvelo zakha khona emzimbeni futhi zingadala ubuhlungu besisu, izinguquko ekucabangeni nasekuziphatheni, noma ezinye izimpawu), ukutheleleka nge-HIV, noma isifo sesibindi.
• utshele udokotela wakho uma ukhulelwe noma uhlela ukukhulelwa. Uma ukhulelwa ngenkathi uthatha i-rifapentine, shayela udokotela wakho.
• ungancelisi ibele ngenkathi uthatha i-rifapentine. I-Rifapentine ingadala ukuthi ubisi lwebele luphenduke lube bomvu-olintshi.
• utshele udokotela wakho uma ugqoka amalensi athintwayo noma amazinyo okufakelwa. I-Rifapentine ingadala amabala abomvu unomphela kumalensi wakho okuxhumana noma emazinyweni okufakelwa.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Rifapentine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ukuguqulwa kwesikhashana (okuphuzi, okubomvu-orange, noma umbala onsundu) kwesikhumba sakho, amazinyo, amathe, umchamo, isitulo, umjuluko nezinyembezi
• isiyezi
• ukuquleka
• ukujuluka okwandayo

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

• isifo sohudo (kufika ezinyangeni ezimbili ngemuva kokwelashwa)
• ukuqubuka
• ukulunywa
• isifuba
• ukukhwehlela ngokuphefumula
• ukuphefumula kanzima
• amehlo abomvu, alumayo, noma acasukile
• imfiva
• amabhamuza
• izinguquko ekucabangeni nasekuziphatheni
• ukuvuvukala kwamehlo, ubuso, izindebe, ulimi, umphimbo, izingalo, izandla, izinyawo, amaqakala noma imilenze engezansi
• ukushaya kwenhliziyo okusheshayo noma okungajwayelekile
• isicanucanu
• ukuhlanza
• ubuhlungu besifuba
• izimpawu ezinjengomkhuhlane, imfiva, ukugodola, ubuhlungu bemisipha, ubuhlungu bemisipha, ukukhathala nekhanda
• ubuhlungu besisu
• ukulahlekelwa isifiso sokudla
• umchamo omnyama
• ubuhlungu obuhlangene noma ukuvuvukala
• ukuphuzi kwesikhumba noma kwamehlo

I-Rifapentine ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• igazi emchameni
• ukulunywa
• ubuhlungu bomzimba noma ukuqina

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho angalawula izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ku-rifapentine.

Ngaphambi kokwenza noma yiluphi uvivinyo lwelabhoratri, tshela udokotela wakho kanye nabasebenzi be-laboratory ukuthi uthatha i-rifapentine.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Priftin^®