Emtricitabine, Rilpivirine, kanye neTenofovir

-Delile

• Ngaphambi kokuthatha i-emtricitabine, i-rilpivirine, ne-tenofovir,
• I-Emtricitabine, i-rilpivirine, ne-tenofovir kungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe ezigabeni EZIBALULEKILE ZESEXWAYISO noma ZOKUQAPHA, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
• Uma uba nokuqubuka okukhulu nganoma iyiphi yalezi zimpawu ezilandelayo, yeka ukuthatha i-emtricitabine, i-rilpivirine, ne-tenofovir bese ushayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

I-Emtricitabine, i-rilpivirine, ne-tenofovir akufanele isetshenziselwe ukwelapha ukutheleleka ngegciwane le-hepatitis B (HBV; ukutheleleka kwesibindi okuqhubekayo). Tshela udokotela wakho uma unayo noma ucabanga ukuthi ungaba ne-HBV. Udokotela wakho angakuhlola ukuthi unayo yini i-HBV ngaphambi kokuba uqale ukwelashwa kwakho nge-emtricitabine, rilpivirine, ne-tenofovir. Uma une-HBV futhi uthatha i-emtricitabine, i-rilpivirine, ne-tenofovir, isimo sakho singase sibe sibi ngokungazelelwe lapho uyeka ukuthatha i-emtricitabine, i-rilpivirine ne-tenofovir. Udokotela wakho uzokuhlola futhi a-oda izivivinyo zelebhu njalo ezinyangeni ezimbalwa ngemuva kokuyeka ukuthatha i-emtricitabine, i-rilpivirine, ne-tenofovir ukubona ukuthi i-HBV yakho iye yaba yimbi yini.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile ngaphambi nangesikhathi sokwelashwa kwakho ukuze ahlole impendulo yomzimba wakho ku-emtricitabine, rilpivirine, ne-tenofovir.

Khuluma nodokotela wakho ngezingozi zokuthatha i-emtricitabine, i-rilpivirine, ne-tenofovir.

Ukuhlanganiswa kwe-emtricitabine, i-rilpivirine, ne-tenofovir kusetshenziselwa ukwelapha i-HIV kubantu abadala nasezinganeni ezinesisindo okungenani esingamakhilogremu angama-35. I-Emtricitabine, i-rilpivirine, ne-tenofovir basesigabeni semithi ebizwa nge-nucleoside ne-nucleotide reverse transcriptase inhibitors (NRTIs). Zisebenza ngokunciphisa ukusabalala kwe-HIV emzimbeni. Yize i-emtricitabine, i-rilpivirine, ne-tenofovir kungeke kuyelaphe i-HIV, le mithi inganciphisa amathuba akho okuba ne-immunodeficiency syndrome (i-AIDS) kanye nezifo ezihlobene ne-HIV ezinjengokutheleleka okunzima noma umdlavuza. Ukuthatha le mithi kanye nokwenza ucansi oluphephile nokwenza ezinye izinguquko kwimpilo yakho kunganciphisa ubungozi bokuthola noma ukudlulisela igciwane le-HIV kwabanye abantu.

Inhlanganisela ye-emtricitabine, i-rilpivirine, ne-tenofovir iza njengethebhulethi ezothathwa ngomlomo. Imvamisa kuthathwa ngokudla (hhayi nje isiphuzo samaprotheni) kanye ngosuku. Thatha i-emtricitabine, i-rilpivirine, ne-tenofovir ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-emtricitabine, i-rilpivirine, ne-tenofovir njengoba nje kuyalelwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Udokotela wakho angakunikeza noma ancoma ukwengezwa kwe-calcium nevithamini D okufanele ukwenze ngesikhathi sokwelashwa kwakho. Kufanele uthathe lezi zithasiselo nsuku zonke njengoba uqondiswe ngudokotela wakho.

Qhubeka nokuthatha i-emtricitabine, i-rilpivirine, ne-tenofovir noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-emtricitabine, i-rilpivirine, ne-tenofovir ngaphandle kokukhuluma nodokotela wakho.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-emtricitabine, i-rilpivirine, ne-tenofovir,

• Tshela udokotela kanye nosokhemisi wakho uma une-aleji ku-emtricitabine, i-rilpivirine, ne-tenofovir, noma imuphi omunye umuthi, noma iziphi izithako ze-emtricitabine, i-rilpivirine, namaphilisi e-tenofovir. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• tshela udokotela wakho uma uthatha i-carbamazepine (Carbatrol, Equetro, Tegretol, abanye), dexamethasone, dexlansoprazole (Dexilant), esomeprazole (Nexium, Vimovo), lansoprazole (Prevacid, e-Prevpac), omeprazole (Prilosec, in Zegerid Oxtellar XR, Trileptal), pantoprazole (Protonix), phenobarbital, phenytoin (Dilantin, Phenytek), rabeprazole (AcipHex), rifampin (Rifadin, Rimactane, eRifamate, eRifater), i-rifapentine (Priftint), noma iSt. Udokotela wakho mhlawumbe uzokutshela ukuthi ungathathi i-emtricitabine, i-rilpivirine, ne-tenofovir uma uthatha eyodwa noma ngaphezulu yale mithi.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: adefovir (Hepsera); i-amiodarone (i-Nexterone, i-Pacerone); ama-antibiotic afana ne-clarithromycin (i-Biaxin, e-Prevpac), i-erythromycin (i-E.E.S., i-Ery-Tab, i-Erythrocin, abanye), i-gentamicin, ne-telithromycin (Ketek); imishanguzo ye-antifungal efana ne-fluconazole (i-Diflucan), i-itraconazole (i-Onmel, i-Sporanox), i-ketoconazole, i-posaconazole (i-Noxafil), ne-voriconazole (i-Vfend); imishanguzo yokulwa nesifo sofuba (anti-TB) efana ne-rifabutin (Mycobutin) ne-rilpivirine (i-Edurant); imishanguzo efana ne-acyclovir (Sitavig, Zovirax), i-cidofovir, i-ganciclovir (i-cytovene), i-valacyclovir (i-Valtrex), ne-valganciclovir (i-Valcyte); i-aspirin neminye imishanguzo yokulwa nokuvuvukala (ama-NSAID) njenge-ibuprofen (Advil, Motrin) ne-naproxen (Aleve, Naprosyn); i-cyclosporine (Gengraf, Neoral, Sandimmune); eminye imithi ye-HIV noma i-AIDS efana ne-lamivudine (Epivir, Epivir-HBV, e-Combivir, Epzicom, Triumeq, Trizivir); eminye imishanguzo ye-HIV equkethe i-emtricitabine, i-rilpivirine, noma i-tenofovir (Atripla, Descovy, Edurant, Emtriva, Genvoya, Odefsey, Stribild, Truvada, Vemlidy, Viread); kanye ne-methadone (i-Dolophine). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• uma uthatha ama-antacid aqukethe i-calcium, i-magnesium, noma i-aluminium (Maalox, Mylanta, Tums, others), thatha i-antacid 2 hours ngaphambi noma okungenani amahora amane ngemuva kokuthatha i-emtricitabine, rilpivirine, ne-tenofovir.
• uma uthatha umuthi we-indigestion, isilungulela, noma izilonda ezifana ne-cimetidine (Tagamet), i-famotidine (i-Pepcid, e-Duexis), i-nizatidine (i-Axid), noma i-ranitidine (i-Zantac), thatha okungenani amahora ayi-12 ngaphambi noma okungenani ama-4 amahora ngemuva kwe-emtricitabine, rilpivirine, ne-tenofovir.
• Tshela udokotela wakho uma uke waba nezimo ezishiwo esigabeni ESIBALULEKILE SESEXWAYISO, ukudangala noma okunye ukugula ngengqondo, izinkinga zamathambo ezibandakanya i-osteoporosis (isimo lapho amathambo eba mncane futhi abe buthakathaka futhi aphuke kalula) noma ukuphuka kwethambo, noma yikuphi uhlobo lokutheleleka olungapheli noma olufika luhambe njengesifo sofuba (i-TB; uhlobo lokutheleleka kwamaphaphu) noma i-cytomegalovirus (i-CMV; ukutheleleka ngegciwane okungadala izimpawu kubantu abanamasosha omzimba abuthakathaka), noma isifo sesibindi noma sezinso .
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha i-emtricitabine, i-rilpivirine, ne-tenofovir, shayela udokotela wakho. Akufanele uncelise ibele uma utheleleke nge-HIV noma uma uthatha i-emtricitabine, i-rilpivirine, ne-tenofovir.
• kufanele wazi ukuthi i-emtricitabine, i-rilpivirine, ne-tenofovir kungadala ushintsho emicabangweni yakho, ekuziphatheni, noma empilweni yengqondo. Shayela udokotela wakho ngokushesha uma uba nezimpawu ezilandelayo ngenkathi uthatha i-emtricitabine, i-rilpivirine, ne-tenofovir: ukucindezeleka okusha noma okuya kuba kubi; ukuzizwa udabukile, ungenathemba, ukhathazekile noma ungenakho ukuthula; noma ucabanga ukuzibulala noma ukuhlela noma ukuzama ukwenza kanjalo.
• kufanele wazi ukuthi ngenkathi uthatha imishanguzo yokwelapha ukutheleleka nge-HIV, amasosha omzimba wakho angaqina futhi aqale ukulwa nezinye izifo ezazivele zisemzimbeni wakho. Lokhu kungadala ukuthi ube nezimpawu zalezo zifo. Uma unezimpawu ezintsha noma eziya ziba zimbi noma kunini ngesikhathi sokwelashwa kwakho nge-emtricitabine, i-rilpivirine, ne-tenofovir, qiniseka ukuthi utshela udokotela wakho.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula ngokudla. Kodwa-ke, uma sekudlule amahora angaphezu kwe-12 kusuka kumthamo wakho wokugcina, weqa umthamo ophuthelwe bese uqhubeka nesimiso sakho sokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Emtricitabine, i-rilpivirine, ne-tenofovir kungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ubunzima bokulala noma ukulala
• amaphupho angajwayelekile
• ushintsho kumbala wesikhumba
• ubuhlungu, ukushisa noma ukuncinza ezandleni noma ezinyaweni
• ikhanda
• isifo sohudo
• ukuqhuma okuncane

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe ezigabeni EZIBALULEKILE ZESEXWAYISO noma ZOKUQAPHA, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukuvuvukala kobuso, umphimbo, ulimi, izindebe, amehlo, izandla, izinyawo, amaqakala noma imilenze engezansi
• ubuhlungu obuqhubekayo noma obukhulayo bethambo
• ubuhlungu bemisipha noma ubuthakathaka
• ukuncipha kokuchama
• ubuhlungu engxenyeni engenhla kwesokudla yesisu
• isicanucanu
• ukuhlanza
• ukulahlekelwa isifiso sokudla
• izimpawu ezinjengomkhuhlane
• ukukhathala ngokweqile
• ukopha okungajwayelekile noma ukulinyazwa
• ubuthakathaka
• isiyezi
• ubumhlophe
• ukushaya kwenhliziyo okusheshayo noma okungajwayelekile
• ukuphefumula kanzima
• umchamo omnyama ophuzi noma onsundu
• ukunyakaza kwamathumbu okukhanyayo
• ukuphuzi kwesikhumba noma kwamehlo
• ukuzwa ukubanda, ikakhulukazi ezandleni noma emilenzeni

Uma uba nokuqubuka okukhulu nganoma iyiphi yalezi zimpawu ezilandelayo, yeka ukuthatha i-emtricitabine, i-rilpivirine, ne-tenofovir bese ushayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukuvuvukala ubuso, izindebe, umlomo, ulimi noma umphimbo
• ubunzima bokugwinya noma ukuphefumula
• izilonda zomlomo noma amabhamuza emzimbeni wakho
• amehlo abomvana futhi avuvukile
• imfiva
• umchamo omnyama
• ubuhlungu ohlangothini lwesokunene sendawo yesisu
• ukuphuzi kwesikhumba noma kwamehlo

I-Emtricitabine, i-rilpivirine, ne-tenofovir kungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Gcina i-emtricitabine, i-rilpivirine, ne-tenofovir esandleni. Ungalindi uze uphelelwe yimithi yokugcwalisa imishanguzo yakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• IComplera^® (njengomkhiqizo ohlanganisiwe oqukethe i-Emtricitabine, i-Rilpivirine, i-Tenofovir)
• U-Odefsey^® (njengomkhiqizo ohlanganisiwe oqukethe i-Emtricitabine, i-Rilpivirine, i-Tenofovir)