I-Selexipag

-Delile

• Ngaphambi kokuthatha i-selexipag,
• I-Selexipag ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

I-Selexipag isetshenziswa kubantu abadala ukwelapha umfutho wegazi ophakeme wamaphaphu (i-PAH, umfutho wegazi ophakeme emithanjeni ethwala igazi uye emaphashini) ukwehlisa ukwanda kwezimpawu futhi kunciphise nethuba lokulaliswa esibhedlela i-PAH. I-Selexipag isekilasini lemithi ebizwa ngokuthi i-nonprostanoid IP prostacyclin receptor agonists. Isebenza ngokuxegisa imithambo yegazi emaphashini ukuvumela igazi ukuba ligeleze kalula.

I-Selexipag iza njengethebhulethi ezothathwa ngomlomo. Imvamisa kuthathwa ngokudla kabili ngosuku. Thatha i-selexipag ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-selexipag njengoba iqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Gwinya wonke amaphilisi; ungawahlukanisi, ungawahlafune noma uwagxoze.

Udokotela wakho mhlawumbe uzokuqala ngomthamo ophansi we-selexipag futhi akhuphule kancane umthamo wakho, hhayi ngaphezu kwesisodwa njalo ngesonto.

I-Selexipag ilawula izimpawu ze-PAH kepha ayiyelaphi. Qhubeka uthathe i-selexipag noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-selexipag ngaphandle kokukhuluma nodokotela wakho.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-selexipag,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-selexipag, noma imiphi eminye imithi, noma iziphi izithako ezibhebheni ze-selexipag. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho i-gemfibrozil (Lopid). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo eminingi ingaxhumana ne-selexipag, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo.
• Tshela udokotela wakho uma ngabe uke waba nesifo se-veno-occlusive pulmonary (PVOD; ukuvinjelwa kwemithambo emaphashini), noma isifo sesibindi.
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha i-selexipag, shayela udokotela wakho.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma kungaphakathi kwamahora angu-6 womthamo olandelayo, weqa umthamo ophuthelwe bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile. Uma uphuthelwa ukuthatha i-selexipag izinsuku ezintathu noma ngaphezulu, khuluma nodokotela wakho ngaphambi kokuthi uqale ukuyithatha futhi. Kuzodingeka uqale kabusha ukuthatha i-selexipag kumthamo ophansi.

I-Selexipag ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ikhanda
• ubuhlungu emhlathini, amalunga, imisipha, izingalo, noma imilenze
• ukuncipha kokudla
• isicanucanu
• isifo sohudo
• ukuhlanza
• ukuqhuma
• ukuqubuka

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukuphelelwa umoya
• ukuphefumula okusheshayo
• isiyezi
• ubuthakathaka

I-Selexipag ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• isicanucanu

Ungavumeli omunye umuntu ukuthi athathe imithi yakho.

I-Selexipag ayitholakali ezikhemisi ezithengisa. Imithi yakho izothunyelwa kuwe ngeposi ekhemisi eliphakathi. Buza udokotela wakho uma unemibuzo mayelana nokuthi uzowuthola kanjani umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Uptravi^®