I-Deutetrabenazine

-Delile

• Ngaphambi kokuthatha i-deutetrabenazine,
• I-Deutetrabenazine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SEXWAYISO, yeka ukuthatha i-deutetrabenazine bese ushayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

I-Deutetrabenazine ingakhuphula ubungozi bokucindezeleka noma imicabango yokuzibulala (ukucabanga ngokuzilimaza noma ukuzibulala noma ukuhlela noma ukuzama ukwenza kanjalo) kubantu abanesifo sikaHuntington (isifo esizuzwe njengefa esidala ukuwohloka okuqhubekayo kwamaseli emizwa ebuchosheni). Tshela udokotela wakho uma uke waba nengcindezi noma wake wacabanga noma uke waba nemicabango yokuzilimaza noma yokuzibulala. Uma unesifo sikaHuntington futhi ucindezelekile noma unemicabango yokuzibulala, udokotela wakho mhlawumbe uzokutshela ukuthi ungathathi i-deutetrabenazine. Wena, umndeni wakho, noma umnakekeli kufanele ushayele udokotela wakho ngokushesha uma uhlangabezana nalezi zimpawu ezilandelayo: ukucindezeleka okusha noma okuya kuba kubi, imicabango yokuzilimaza noma ukuzibulala noma ukuhlela noma ukuzama ukwenza kanjalo, ukukhathazeka ngokweqile, ukuphazamiseka, ubunzima bokulala noma ukuhlala ulele, ukuziphatha okunolaka noma okunenzondo, ukucasuka, ukwenza ngaphandle kokucabanga, ukungahlaliseki okukhulu, ukukhathazeka, ukushintsha kwesisindo somzimba, ukulahlekelwa intshisekelo ekuxhumaneni nomphakathi, ubunzima bokunaka, noma ezinye izinguquko ezingajwayelekile zokuziphatha. Qiniseka ukuthi umndeni wakho noma umnakekeli uhlola wena njalo futhi uyazi ukuthi yiziphi izimpawu ezingaba zimbi kakhulu ukuze bakwazi ukushayela udokotela uma ungakwazi ukufuna ukwelashwa uwedwa.

Gcina wonke ama-aphoyintimenti nodokotela wakho. Udokotela wakho mhlawumbe uzofuna ukukhuluma nawe ngempilo yakho yengqondo ngenkathi uthatha lo muthi.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa nge-deutetrabenazine futhi isikhathi ngasinye lapho ugcwalisa umuthi wakho. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) noma iwebhusayithi yomkhiqizi ukuthola i-Medication Guide.

I-Deutetrabenazine isetshenziselwa ukwelapha i-chorea (ukunyakaza okungazelelwe ongakwazi ukukulawula) okubangelwa yisifo sikaHuntington (isifo esizuzwe njengefa esibangela ukuwohloka okuqhubekayo kwamaseli ezinzwa ebuchosheni). Ibuye isetshenziselwe ukwelapha i-tardive dyskinesia (ukunyakaza okungalawuleki kobuso, ulimi, noma ezinye izitho zomzimba). I-Deutetrabenazine isekilasini lemithi ebizwa nge-vesicular monoamine transporter 2 (VMAT2) inhibitors. Isebenza ngokushintsha ukusebenza kwezinto ezithile zemvelo ebuchosheni ezithinta izinzwa nemisipha.

I-Deutetrabenazine iza njengethebhulethi ezothathwa ngomlomo. Ezigulini ezinesifo sikaHuntington, imvamisa zithathwa ngokudla kanye ngosuku ekuqaleni bese zikhushulwa kabili ngosuku. Ezigulini ezine-tardive dyskinesia, imvamisa ithathwa ngokudla kabili ngosuku. Thatha i-deutetrabenazine cishe ngesikhathi esifanayo (ama) nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-deutetrabenazine njengoba nje iyalelwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Gwinya wonke amaphilisi; ungawahlukanisi, ungawahlafune noma uwagxoze.

Udokotela wakho kungenzeka akuqale ngomthamo ophansi we-deutetrabenazine futhi akhuphule kancane umthamo wakho, hhayi ngaphezu kwesisodwa njalo ngesonto.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-deutetrabenazine,

• Tshela udokotela wakho kanye nosokhemisi uma une-allergies ku-deutetrabenazine, noma imuphi omunye umuthi, noma iziphi izithako ezikumaphilisi e-deutetrabenazine. Isebenza ngokushintsha ukusebenza kwezinto ezithile zemvelo ebuchosheni. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho uma uthatha i-reserpine, tetrabenazine (Xenazine), i-valbenazine (Ingrezza), noma i-monoamine oxidase (MAO) inhibitor efana ne-isocarboxazid (Marplan), linezolid (Zyvox), methylene blue, phenelzine (Nardil), selegiline (Eldeprylline) , Emsam, Zelapar), ne-tranylcypromine (i-Parnate), noma uma uyekile ukuthatha i-monoamine oxidase inhibitor emasontweni amabili edlule noma uyeke ukuthatha i-reserpine ezinsukwini ezingama-20 ezedlule. Udokotela wakho mhlawumbe uzokutshela ukuthi akufanele uthathe i-deutetrabenazine.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qinisekisa ukusho noma yikuphi kokulandelayo: imithi yokukhathazeka; imishanguzo efana ne-bupropion (i-Aplenzin, i-Wellbutrin, i-Zyban), i-fluoxetine (i-Prozac, i-Sarafem, i-Selfemra), ne-paroxetine (i-Brisdelle, i-Paxil, i-Pexeva); ama-antipsychotic afana ne-chlorpromazine, i-haloperidol (i-Haldol), i-olanzapine (i-Zyprexa), i-quetiapine (i-Seroquel), i-risperidone (i-Risperdal), i-thioridazine, ne-ziprasidone (i-Geodon); imithi ethile yokushaya kwenhliziyo okungajwayelekile njenge-amiodarone (Nexterone, Pacerone), i-procainamide, i-quinidine (eNuedexta), ne-sotalol (iBetapace, iSorine, iSotylize); moxifloxacin (Avelox); imithi yokuquleka; isidambisi, amaphilisi okulala, noma okokuqeda ukuthula. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• tshela udokotela wakho uma unesifo sesibindi. Udokotela wakho mhlawumbe uzokutshela ukuthi ungathathi i-deutetrabenazine.
• Tshela udokotela wakho uma ngabe uke waba ne-QT syndrome isikhathi eside (isimo esandisa ingozi yokuhlaselwa ukushaya kwenhliziyo okungajwayelekile okungadala ukuquleka noma ukufa ngokuzumayo) noma olunye uhlobo lokushaya kwenhliziyo okungajwayelekile noma inkinga yesigqi senhliziyo. Phinda utshele udokotela wakho uma unamazinga aphansi egazi we-magnesium noma i-potassium egazini lakho noma umdlavuza webele.
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha i-deutetrabenazine, shayela udokotela wakho.
• kufanele wazi ukuthi i-deutetrabenazine ingakwenza ukozele noma ibangele ukukhathala. Ungashayeli imoto noma usebenzise imishini uze wazi ukuthi lo muthi ukuthinta kanjani.
• kufanele wazi ukuthi utshwala bungangezela ukozela okubangelwa yilomuthi.Ungaphuzi utshwala ngenkathi uthatha i-deutetrabenazine.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

Uma uphuthelwa ukuthatha i-deutetrabenazine isikhathi esingaphezu kwesonto, khuluma nodokotela wakho ngaphambi kokuqala ukuthatha futhi. Kuzodingeka uqale kabusha ukuyithatha ngomthamo ophansi.

I-Deutetrabenazine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isifo sohudo
• ukuqunjelwa
• umlomo owomile
• ukukhathala
• ubuhlungu noma ukushisa lapho uchama
• ukulinyazwa
• ukutheleleka okuphezulu kokuphefumula

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SEXWAYISO, yeka ukuthatha i-deutetrabenazine bese ushayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• umkhuhlane, ukujuluka, ukudideka, ukushaya kwenhliziyo okusheshayo noma okungajwayelekile, nokuqina kwemisipha okunzima
• ukuzamazama, ukuqina, noma ubunzima bokuhambisa noma ukugcina ibhalansi yakho
• ukuwa
• ukushaya kwenhliziyo okungajwayelekile noma okusheshayo
• ukuquleka

I-Deutetrabenazine ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Ukugcine ekamelweni lokushisa kude nokukhanya, ukushisa okweqile nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• ukunyakaza okusontayo noma okunyikinyikisayo
• ukunyakaza kweso okusheshayo
• isicanucanu
• ukuhlanza
• ukujuluka
• ukuthambisa
• ukudideka
• isifo sohudo
• ukubona izinto ezingekho (ukubona into noma ukuzwa amazwi angekho)
• ukubomvu kwesikhumba
• ukuzamazama okungalawuleki

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• U-Austedo^®