Ukujova kweGuselkumab

-Delile

• Ngaphambi kokusebenzisa umjovo we-guselkumab,
• Umjovo we-Guselkumab ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, yeka ukusebenzisa umjovo we-guselkumab bese ushayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

Umjovo we-Guselkumab usetshenziselwa ukwelapha i-plaque psoriasis ngokulinganisela (isifo sesikhumba lapho kwakhiwa khona amabala abomvu, anezikhala kwezinye izindawo zomzimba) kubantu abadala abane-psoriasis enzima kakhulu ukuthi ingalashwa yimithi yokwelapha kuphela. Ibuye isetshenziswe yodwa noma ihlanganiswe neminye imithi yokwelapha i-psoriatic arthritis (isimo esidala ubuhlungu bamalunga nokuvuvukala nezikali esikhunjeni) kubantu abadala. Umjovo we-Guselkumab usesigabeni semithi ebizwa ngama-antibody monoclonal. Isebenza ngokumisa ukusebenza kwamaseli athile emzimbeni adala izimpawu ze-psoriasis.

Umjovo we-Guselkumab uza njengesixazululo (uketshezi) kusirinji ekhethiwe kanye nedivayisi yomjovo othomathikhi oyifakayo ukujova ngomgogodla (ngaphansi kwesikhumba). Imvamisa ijovwa kanye njalo emavikini ama-4 emithamo emibili yokuqala bese iqhubeka kanye njalo emavikini ayisishiyagalombili. Sebenzisa umjovo we-guselkumab njengoba uqondisiwe. Ungayifaki ngaphezulu noma ngaphansi kwayo noma uyijoje kaningi kunokuyalelwa ngudokotela wakho.

Uzothola umthamo wakho wokuqala womjovo we-guselkumab ehhovisi likadokotela wakho. Ngemuva kwalokho, udokotela wakho angakuvumela ukuthi ujove i-guselkumab ngokwakho noma unakekelwa unikeze imijovo. Cela udokotela wakho noma usokhemisi ukuthi akubonise noma umuntu ozobe efaka imijovo yokujova i-guselkumab. Ngaphambi kokusebenzisa umjovo we-guselkumab okokuqala, funda imiyalelo ebhaliwe eza nayo.

Sebenzisa i-syringe ngayinye noma i-othomathikhi yedivayisi yokujova kanye kuphela bese ujova sonke isixazululo kusirinji. Lahla isirinji noma idivaysi esetshenzisiwe ngisho noma kusekhona umuthi othile osele kuyo. Lahla imijovo noma amadivaysi asetshenzisiwe esitsheni esingamelana nokubhoboza. Khuluma nodokotela wakho noma usokhemisi mayelana nokuthi ungasilahla kanjani isitsha esingamelana nokubhoboza.

Susa isipontsho noma umjovo othomathikhi esiqandisini, beka isirinji endaweni eyisicaba ngaphandle kokukhipha ikhava yenaliti noma ikepisi, bese uyivumela ifudumale ekamelweni lokushisa imizuzu engama-30 ngaphambi kokuba ulungele ukujova umuthi. Ungazami ukufudumeza umuthi ngokuwufudumeza ngemicrowave, uwufake emanzini ashisayo, uwushiye elangeni, noma nganoma iyiphi enye indlela.

Unganyakazisi isirinji ekhethiwe noma umjovo ozenzakalelayo oqukethe i-guselkumab. Ungayisebenzisi isipontsho esenziwe guselkumab uma yehlisiwe; inezingxenye zengilazi futhi kufanele iphathwe ngokucophelela.

Njalo bheka isisombululo se-guselkumab ngaphambi kokusijova. Bheka ukuthi usuku lokuphelelwa yisikhathi aludlulanga nokuthi uketshezi lucacile futhi alunambala ukuze kukhanyiswe isisombululo esiphuzi. Uketshezi lungaqukatha izinhlayiya ezimbalwa ezibonakalayo. Ungasebenzisi isirinji noma idivaysi oyikhethile uma yonakele, iphelelwe yisikhathi, iqandisiwe, noma uma uketshezi lunamafu, lubala, noma luqukethe izinhlayiya ezinkulu.

Jova umjovo we-guselkumab kungakapheli imizuzu engu-5 ukhipha ikhava yenaliti noma ikepisi ledivayisi. Ungafaki ikhava yenaliti noma ikepisi ledivayisi ngoba lokhu kungalimaza inaliti noma kulimaze. Ungasebenzisi i-othomathikhi yedivayisi yomjovo eyehlisiwe ngemuva kokukhishwa kukhephu wedivayisi.

Ungajova umjovo we-guselkumab noma yikuphi ngaphambili kwamathanga akho (umlenze ongaphezulu), emuva kwezingalo ezingaphezulu, noma isisu (isisu) ngaphandle kwenkaba yakho nendawo engamasentimitha ama-5 ukuyizungeza. Ukwehlisa amathuba okuba buhlungu noma okubomvu, sebenzisa isiza esihlukile ngomjovo ngamunye. Musa ukujova endaweni lapho isikhumba sithambile, silimele, sibomvu, siqinile.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa ngomjovo we-guselkumab. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) ukuthola uMhlahlandlela Wezokwelapha, noma iwebhusayithi yomkhiqizi ukuthola uMhlahlandlela Wezokwelapha kanye Nemiyalo Ukusetshenziswa.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokusebenzisa umjovo we-guselkumab,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane kumjovo we-guselkumab, noma imuphi omunye umuthi, noma iziphi izithako zomjovo we-guselkumab. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi usebenzisa umjovo we-guselkumab, shayela udokotela wakho.
• thintana nodokotela wakho ukuze ubone uma ngabe udinga ukuthola noma yimiphi imigomo. Kubalulekile ukuthi yonke imishanguzo yokugoma ilungele iminyaka yakho ngaphambi kokuqala ukwelashwa kwakho ngomjovo we-guselkumab. Ungabi nayo imigomo ngesikhathi sokwelashwa kwakho ngaphandle kokukhuluma nodokotela wakho. Futhi khuluma nodokotela wakho uma noma ngubani ekhaya lakho edinga ukuthola umuthi wokugoma ngesikhathi sokwelashwa kwakho ngomjovo we-guselkumab.
• kufanele wazi ukuthi umjovo we-guselkumab unganciphisa ikhono lakho lokulwa nokutheleleka kusuka kuma-bacteria, amagciwane, nesikhunta futhi kwandise ingozi yokuthi uzothola ukutheleleka okungathi sína noma okusongela ukuphila. Tshela udokotela wakho uma uvame ukuthola noma yiluphi uhlobo lokutheleleka noma uma une noma ucabanga ukuthi ungahle ube nolunye uhlobo lokutheleleka manje. Lokhu kufaka izilonda zesikhumba ezintsha noma ezishintshayo, ukutheleleka okuncane (njengokusikeka okuvulekile noma izilonda), izifo ezifikayo (ezifana nezilonda ezibandayo), kanye nezifo ezingapheli ezingapheli. Uma uhlangabezana nalezi zimpawu ezilandelayo ngesikhathi noma ngemuva nje kokwelashwa kwakho ngomjovo we-guselkumab, shayela udokotela wakho ngokushesha: ukujuluka; Ukugodola; ubuhlungu bemisipha; ukukhwehlela; ukuphelelwa umoya; imfiva; ukuncipha komzimba; ukukhathala ngokweqile; izimpawu ezinjengomkhuhlane; ukuhlanza; Umphimbo obuhlungu; ukugijima, ikhala eligxishiwe, noma ukuthimula; isikhumba esifudumele, esibomvu, noma esibuhlungu; ukuchama okubuhlungu noma okuvamile; isifo sohudo; ubuhlungu besisu; noma ezinye izimpawu zokutheleleka.
• kufanele wazi ukuthi ukusebenzisa umjovo we-guselkumab kwandisa ubungozi bokuthi uzoba nesifo sofuba (i-TB; ukutheleleka okungathi sína kwamaphaphu), ikakhulukazi uma usuvele ungenwe yisifo sofuba kodwa ungenazo izimpawu zesifo. Tshela udokotela wakho uma uke waba ne-TB noma wake waba nayo, uma ngabe uhlala ezweni lapho i-TB ijwayelekile khona, noma uma wake waba seduze komuntu one-TB. Udokotela wakho uzokuhlolela isikhumba ukuze abone ukuthi une-TB engasebenzi yini. Uma kunesidingo, udokotela wakho uzokunika imithi yokwelapha lesi sifo ngaphambi kokuba uqale ukusebenzisa umjovo we-guselkumab. Uma unezinye zalezi zimpawu ezilandelayo ze-TB, noma uma uba nalezi zimpawu phakathi nokwelashwa kwakho, shayela udokotela wakho ngokushesha: ukukhwehlela, ubuhlungu besifuba, ukukhwehlela igazi noma amafinyila, ubuthakathaka noma ukukhathala, ukwehla kwesisindo, ukungathandi ukudla, Ukugodola, umkhuhlane, noma ukujuluka ebusuku.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Sebenzisa umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula bese uqhubeka nesimiso sakho sokulinganisa okuvamile. Ungasebenzisi umthamo ophindwe kabili ukwenza okulahlekile. Shayela udokotela wakho uma ungacaciswanga ngohlelo lwakho lokulinganisa.

Umjovo we-Guselkumab ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ikhanda
• ububomvu, ukulunywa, ukuvuvukala, ubuhlungu, ukushintsha kombala, noma ukucasuka endaweni yokujova
• ubuhlungu obuhlangene
• isifo sohudo

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, yeka ukusebenzisa umjovo we-guselkumab bese ushayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukuqubuka
• isifuba
• ukulunywa
• ukuzizwa uphela amandla noma unekhanda elincane
• ukuvuvukala kobuso, amehlo, izindebe, umlomo, umphimbo, noma ulimi
• ukuphefumula kanzima
• ukuqina kwesifuba noma umphimbo

Umjovo we-Guselkumab ungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi usebenzisa lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina umjovo we-guselkumab esiqandisini, kepha ungafrizi. Gcina imijovo oyifakile noma okokufaka okuzenzakalelayo komjovo emabhokisini abo okuqala ukuwavikela ekukhanyeni.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho.

Ungavumeli omunye umuntu asebenzise imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Tremfya^®