Eliglustat

-Delile

• Ngaphambi kokuthatha i-eliglustat,
• I-Eliglustat ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

I-Eliglustat isetshenziselwa ukwelapha uhlobo lwesifo i-Gaucher 1 (isimo lapho into ethile enamafutha ingaphuli ngokwejwayelekile emzimbeni futhi yakha kwezinye izitho futhi ibangele izinkinga zesibindi, ubende, amathambo, negazi) kubantu abathile. U-Eliglustat usesigabeni semithi ebizwa nge-enzyme inhibitors. Isebenza ngokuvimbela umzimba ukuthi ungakhiqizi into enamafutha ukuze kuncane okuzokwakha emzimbeni futhi kudale izimpawu.

U-Eliglustat uza njengephilisi elizothathwa ngomlomo. Imvamisa kuthathwa kanye noma kabili ngosuku noma ngaphandle kokudla. Thatha i-eliglustat cishe ngesikhathi esifanayo (ama) nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-eliglustat njengoba nje kuqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Abanye abantu bangaphendula ngokuhlukile kwi-eliglustat ngokuya ngofuzo lwabo noma ukwakheka kofuzo. Udokotela wakho uzoku-oda ukuhlolwa kwegazi ukusiza ukuthola umthamo we-eliglatat okungcono kakhulu kuwe.

Gwinya wonke amaphilisi ngamanzi; ungawahlukanisi, uwavule, uwaqede noma uwagxoze.

I-Eliglustat ilawula isifo seGaucher kodwa ayiselaphi. Qhubeka nokuthatha i-eliglustat noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-eliglustat ngaphandle kokukhuluma nodokotela wakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-eliglustat,

• Tshela udokotela wakho kanye nosokhemisi uma ungenwe i-eliglustat, noma imiphi eminye imithi, noma iziphi izithako ezikuma-capsule we-eliglustat. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma ikuphi kokulandelayo: amitriptyline; imithi ethile yokushaya kwenhliziyo okungajwayelekile njenge-amiodarone (Nexterone, Pacerone), digoxin (Lanoxin), i-quinidine (eNuedexta), i-procainamide, ne-sotalol (iBetapace, iSorine, iSotylize); i-bupropion (i-Aplenzin, iZyban, ku-Contrave); i-cimetidine (Tagamet); i-clarithromycin (i-Biaxin, ku-Prevpac), i-digoxin; i-diltiazem (Cardizem, Tiazac, abanye); i-duloxetine (iCymbalta); i-erythromycin; i-fluconazole (iDiflucan); i-fluoxetine (i-Prozac, i-Sarafem); indinavir (Crixivan), itraconazole (Onmel, Sporanox), ketoconazole (Nizoral), metoprolol (Toprol); nefazodone, nelfinavir (Viracept), paroxetine (Paxil); i-rifampin (i-Rifadin, i-Rimactane); i-ritonavir (i-Norvir, e-Kaletra, e-Viekira Pak), imithi yokwelashwa okufana ne-carbamazepine (i-Carbatrol, i-Equetro, i-Tegretol, abanye), i-phenobarbital, ne-phenytoin (i-Dilantin, i-Phenytek); i-sertraline (iZoloft); i-terbinafine (iLamisil); kanye ne-verapamil (Calan, Verelan, abanye); Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imithi eminingi ingase futhi ihlanganyele ne-eliglustat, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu. Phinda utshele udokotela noma usokhemisi wakho uma usebenzisa le mithi elandelayo: i-enzyme therapy esikhundleni se-imiglucerase (Cerezyme), taliglucerase alfa (Elelyso), noma i-velaglucerase alfa (Vpriv). Uzodinga ukulinda amahora angama-24 ngemuva komthamo wokugcina wale mithi yokufaka esikhundleni se-enzyme ngaphambi kokuba uqale ukuthatha i-eliglustat.
• utshele udokotela wakho ukuthi uthatha miphi imikhiqizo yamakhambi, ikakhulukazi iSt John's wort.
• tshela udokotela wakho uma unesifo sesibindi. Ngokuya ngemiphumela yokuhlolwa kwegazi lakho ukuthola ukwakheka kofuzo lwakho, udokotela wakho angakutshela ukuthi ungathathi i-eliglatat njengoba abantu abathile kungafanele bathathe umuthi wedwa noma ngokuhambisana neminye imithi, uma benesifo sesibindi, noma uma ube nenhlanganisela yezimo ezithile zokwelashwa nemithi.
• Tshela udokotela wakho uma ngabe uke waba ne-QT syndrome isikhathi eside (isimo esandisa ingozi yokuhlaselwa ukushaya kwenhliziyo okungajwayelekile okungadala ukuquleka noma ukufa ngokuzuma), noma olunye uhlobo lokushaya kwenhliziyo okungajwayelekile noma inkinga yesigqi senhliziyo, noma uma une owake wahlaselwa yisifo senhliziyo, ukuhluleka kwenhliziyo, noma inhliziyo, noma isifo sezinso.
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha i-eliglatat, shayela udokotela wakho.

Ungadli isithelo samagilebhisi noma uphuze ijusi lamagilebhisi ngenkathi uthatha lo muthi.

Uma uphuthelwa umthamo, thatha umthamo olandelayo ngesikhathi esijwayelekile bese uqhubeka nesimiso sakho sokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Eliglustat ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ukukhathala
• ubuthakathaka
• ubuhlungu obuhlangene
• ikhanda
• migraine
• isicanucanu
• isilungulela
• igesi
• ubuhlungu bomlomo nomphimbo
• isifo sohudo
• ukuhlungu obusemhlane
• ubuhlungu emilenzeni nasezingalweni
• ubuhlungu besisu
• ukukhwehlela
• ukuqubuka

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

• ukushaya kwenhliziyo, isiyezi, noma ukuquleka

I-Eliglustat ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• isiyezi
• ukungazinzi
• isicanucanu
• ukuhlanza

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho anga-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ku-eliglustat.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• UCerdelga^®