IBinimetinib

-Delile

• Ngaphambi kokuthatha i-binimetinib,
• I-Binimetinib ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

I-Binimetinib isetshenziswa kanye ne-encorafenib (Braftovi) ukwelapha izinhlobo ezithile ze-melanoma (uhlobo lomdlavuza wesikhumba) oluye lwasakazekela kwezinye izingxenye zomzimba noma olungasuswa ngokuhlinzwa. UBinimetinib usesigabeni semithi ebizwa nge-kinase inhibitors. Isebenza ngokuvimba ukusebenza kweprotheni engavamile ekhombisa ukuthi amangqamuzana omdlavuza ayanda. Lokhu kusiza ukumisa noma ukubambezela ukusabalala kwamangqamuzana omdlavuza.

I-Binimetinib iza njengethebhulethi ezothathwa ngomlomo. Imvamisa kuthathwa noma ngaphandle kokudla kabili ngosuku, cishe amahora angama-12 ahlukene. Thatha i-binimetinib ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-binimetinib njengoba nje kuqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Uma uhlanza ngemuva kokuphuza umuthi, ungathathi omunye umthamo. Qhubeka nesimiso sakho sokulinganisa okuvamile.

Udokotela wakho angancipha noma ayeke ukwelashwa kwakho okwesikhashana noma unomphela kuye ngokuthi uhlangabezana yini neminye imiphumela engemihle. Qiniseka ukuthi utshela udokotela wakho ukuthi uzizwa kanjani ngesikhathi sokwelashwa kwakho nge-binimetinib.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-binimetinib,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-binimetinib, noma imuphi omunye umuthi, noma iziphi izithako ezikumaphilisi e-binimetinib. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunomsoco, okwenzayo noma ohlela ukukuthatha. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• utshele udokotela wakho uma uke waba nesifo senhliziyo noma sesibindi.
• utshele udokotela wakho uma ukhulelwe noma uhlela ukukhulelwa. Kuzofanele wenze ukuhlolwa kokukhulelwa ngaphambi kokuqala ukwelashwa. Kufanele usebenzise ukulawulwa kokubeletha ukuvimbela ukukhulelwa ngesikhathi sokwelashwa kwakho nge-binimetinib nezinsuku ezingama-30 ngemuva komthamo wakho wokugcina. Khuluma nodokotela wakho ngezindlela zokulawula ukubeletha ezizokusebenzela. Uma ukhulelwa ngenkathi uthatha i-binimetinib, shayela udokotela wakho ngokushesha. I-Binimetinib ingalimaza umbungu.
• tshela udokotela wakho uma uncelisa. Ungancelisi ibele ngenkathi uthatha i-binimetinib nezinsuku ezi-3 ngemuva komthamo wakho wokugcina.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma kungaphakathi kwamahora angu-6 womthamo olandelayo, weqa umthamo ophuthelwe bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Binimetinib ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ukukhathala
• isicanucanu
• isifo sohudo
• ukuhlanza
• ubuhlungu besisu
• ukuqunjelwa
• isiyezi

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

• izinguquko zombono noma ubuhlungu beso, ukuvuvukala, noma ubomvu
• umkhuhlane, umphimbo obuhlungu, amakhaza, ukukhwehlela, noma ezinye izimpawu zokutheleleka
• amehlo aphuzi noma isikhumba, umchamo omnyama, ukulahlekelwa isifiso sokudla, ukukhathala, noma ubuhlungu noma ukungaphatheki kahle endaweni yesisu ephezulu
• ubuthakathaka obungavamile, ubuhlungu bemisipha, noma umchamo obomvu obomvu noma onsundu
• ukopha okungavamile noma ukulimaza; okumnyama, okulindile, noma okungaphansi kwegazi; noma ukukhwehlela igazi
• ukuphefumula noma ukukhwehlela
• ukuqala ngokungazelelwe kobunzima bokuphefumula; ubuhlungu besifuba; ukuvuvukala kwezinyawo, amaqakala, noma imilenze engezansi; noma ubuhlungu bomlenze, imfudumalo, noma ukuvuvukala
• ukushesha, ukushaya kwenhliziyo; ukuphelelwa umoya; ukuvuvukala kwamaqakala nezinyawo; noma isiyezi

I-Binimetinib ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina konke ukubonana nodokotela wakho, udokotela wamehlo, kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu, kufaka phakathi izivivinyo zamehlo, ukuhlola impendulo yomzimba wakho ku-binimetinib.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• UMektovi^®