Umjovo weCemiplimab-rwlc

-Delile

• Ngaphambi kokuthola umjovo we-cemiplimab-rwlc,
• Umjovo weCemiplimab-rwlc ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezisesigabeni se-HOW, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

Umjovo weCemiplimab-rwlc usetshenziselwa ukwelapha izinhlobo ezithile ze-cutaneous squamous cell carcinoma (CSCC; umdlavuza wesikhumba) osabalele kwizicubu eziseduze futhi ongeke welashwe kahle ngokuhlinzwa noma ngemithi yokwelashwa ngemisebe, noma esenabele kwezinye izingxenye zomzimba. Ibuye isetshenziselwe ukwelapha i-basal cell carcinoma engenakususwa ngokuhlinzwa noma isabalale kwezinye izingxenye zomzimba ngemuva kokwelashwa ngomunye umuthi, noma uma lowo muthi ungeke usetshenziswe. Umjovo weCemiplimab-rwlc uphinde usetshenziselwe ukwelapha uhlobo oluthile lomdlavuza wamaphaphu weseli (non-small cell) (NSCLC) osabalalele ezicutshini eziseduze futhi ongeke ususwe ngokuhlinzwa noma welashwe ngamakhemikhali noma ngemisebe noma usabalalele kwezinye izingxenye zomzimba. Umjovo weCemiplimab-rwlc usesigabeni semithi ebizwa ngama-antibody monoclonal. Isebenza ngokubulala umdlavuza.

Umjovo weCemiplimab-rwlc uza njengesisombululo (uketshezi) ukujova ngomjovo (emthanjeni) ngaphezu kwemizuzu engama-30 ngudokotela noma umhlengikazi esikhungweni sezokwelapha noma esikhungweni sokumnika. Imvamisa inikezwa njalo emavikini amathathu.

Udokotela wakho kungadingeka ukuthi anciphise ukumnika kwakho, noma aphazamise noma ayeke ukwelashwa kwakho uma uhlangabezana nemiphumela ethile emibi. Tshela udokotela wakho ngokushesha uma uhlangabezana nalezi zimpawu ezilandelayo ngesikhathi noma ngemuva kokumnika: ukugodola noma ukuqhaqhazela, umkhuhlane, ukulunywa, ukuqubuka, ukuzwa ukuquleka, ukuqhuma, isicanucanu, ubuhlungu emuva noma entanyeni, ukuphefumula, isizungu, ukuhefuzela, noma ubuso ukuvuvukala.

Udokotela wakho angabambezela, noma ayeke ukwelashwa kwakho ngomjovo we-cemiplimab-rwlc ngokuya ngempendulo yakho emithini kanye neminye imiphumela emibi ohlangabezana nayo. Khuluma nodokotela wakho mayelana nokuthi uzizwa kanjani ngesikhathi nangemva kokwelashwa kwakho.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa ngomjovo we-cemiplimab-rwic futhi isikhathi ngasinye lapho uthola umthamo. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) noma iwebhusayithi yomkhiqizi ukuthola i-Medication Guide.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola umjovo we-cemiplimab-rwlc,

• Tshela udokotela kanye nosokhemisi wakho uma ungenwe i-cemiplimab-rwlc injection, noma imuphi omunye umuthi, noma iziphi izithako zomjovo we-cemiplimab-rwlc. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• Tshela udokotela wakho uma ngabe uthole noma uhlela ukuthola ukufakelwa kwe-stem cell esebenzisa ama-stem stem cell (allogeneic) noma owake wafakelwa isitho esithile. Futhi, tshela udokotela wakho uma ngabe uke waba nesifo sikashukela noma sesike saba khona, isifo sikaCrohn (isimo lapho umzimba uhlasela ulwelwesi lwendlela yokugaya ukudla, ubangele ubuhlungu, isifo sohudo, ukuncipha komzimba nomkhuhlane), i-ulcerative colitis (isimo esibangela ukuvuvukala nezilonda emgqeni wekholoni [amathumbu amakhulu] ne-rectum), i-lupus (isifo lapho umzimba uhlasela khona izitho eziningi zaso), isifo sezinzwa ezifana ne-myasthenia gravis (ukuphazamiseka kwesistimu yezinzwa okubangela ubuthakathaka bemisipha), isifo samaphaphu noma izinkinga zokuphefumula, noma i-thyroid, isifo sesibindi noma sezinso.
• utshele udokotela wakho uma ukhulelwe noma uhlela ukukhulelwa. Akufanele ukhulelwe ngenkathi uthola umjovo we-cemiplimab-rwlc. Uzodinga ukuhlolwa kokukhulelwa ngaphambi kokuba uqale ukuthola le mithi. Sebenzisa ukulawulwa kokubeletha okusebenzayo ngesikhathi sokwelashwa kwakho ngomjovo we-cemiplimab-rwlc kanye nezinyanga ezine ngemuva komthamo wakho wokugcina. Uma ukhulelwa ngenkathi uthola umjovo we-cemiplimab-rwlc, shayela udokotela wakho. Umjovo weCemiplimab-rwlc ungalimaza umbungu.
• tshela udokotela wakho uma uncelisa. Udokotela wakho uzokutshela ukuthi ungancelisi ngesikhathi sokwelashwa kwakho ngomjovo we-cemiplimab-rwlc kanye nezinyanga ezi-4 ngemuva komthamo wakho wokugcina.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Umjovo weCemiplimab-rwlc ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ukuqunjelwa

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezisesigabeni se-HOW, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukukhwehlela; ukushaya kwenhliziyo okungajwayelekile; ubuhlungu besifuba; noma ukuphefumula okuncane
• isifo sohudo; indle emnyama, elindile, enamathelayo, noma enegazi noma amafinyila; noma ubuhlungu besisu noma isisa
• amehlo aphuzi noma isikhumba; isicanucanu noma ukuhlanza okukhulu; umchamo omnyama; ukulahlekelwa ukudla; ukopha okungavamile noma ukulimaza; noma ubuhlungu noma ukungaphatheki kahle endaweni engaphezulu yesisu
• ukuqubuka; isikhumba esishayayo; ukulunywa; ama-lymph node avuvukile; izilonda noma izilonda emlonyeni noma ekhaleni, emphinjeni, noma esithweni sangasese
• ukuncipha kwenani lomchamo; ukuvuvukala emaqakaleni akho; igazi emchameni; ukulahlekelwa isifiso sokudla
• ikhanda, ukuzwa ukulamba noma ukoma kakhulu kunokujwayelekile; ukujuluka okwandayo; ukukhathala ngokweqile; ukuchama njalo; isicanucanu; ukuhlanza; noma izinguquko zesisindo
• umbono ophindwe kabili, ukungaboni kahle, ukuzwela kwamehlo ekukhanyeni, ubuhlungu bamehlo, noma izinguquko kumbono
• ukuzwa ukubanda; ukujula kwezwi noma ukushaqeka; ukulahleka kwezinwele; ukucasuka; isiyezi noma ukuquleka; ukushaya kwenhliziyo okusheshayo; ukukhohlwa; noma ushintsho esifisweni socansi
• ukudideka, ukulala, izinkinga zememori, ukuguquka kwemizwelo noma isimilo, intamo elukhuni, izinkinga zokulinganisela, noma ukuncinza noma ukuba ndikindiki kwezingalo noma imilenze
• ubuhlungu bemisipha noma ubuthakathaka noma amajaqamba emisipha

Umjovo weCemiplimab-rwlc ungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthola lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Uma welashelwa i-NSCLC, udokotela wakho uzoku-oda ukuhlolwa kwelebhu ngaphambi kokuba uqale ukwelashwa kwakho ukuze ubone ukuthi umdlavuza wakho ungelashwa nge-cemiplimab-rwlc. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho kumjovo we-cemiplimab-rwlc.

Buza usokhemisi wakho noma imiphi imibuzo onayo ngomjovo we-cemiplimab-rwlc.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Libtayo^®