Umjovo we-Emapalumab-lzsg

-Delile

• Ngaphambi kokuthola umjovo we-emapalumab-lzsg,
• Umjovo we-Emapalumab-lzsg ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu noma lezo ezisohlwini lwe-HOW section kanye ne-SPECIAL PRECAUTIONS section, yeka ukuthatha umjovo we-emapalumab-lzsg bese ushayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

Umjovo we-Emapalumab-lzsg usetshenziselwa ukwelapha abantu abadala nezingane (ezisanda kuzalwa nangaphezulu) nge-hemophagocytic lymphohistiocytosis (HLH; isimo esizuzwe njengefa lapho amasosha omzimba engasebenzi khona ngokujwayelekile futhi adale ukuvuvukala nokulimala esibindini, ebuchosheni nasemnkantsheni wethambo) onesifo esingakathuthuki, sesibe sibi kakhulu, noma sibuye emuva kokwelashwa kwangaphambilini noma abangakwazi ukuthatha eminye imithi. Umjovo we-Emapalumab-lzsg usesigabeni semithi ebizwa ngama-antibody monoclonal. Isebenza ngokuvimba ukusebenza kweprotheni ethile kumasosha omzimba ebangela ukuvuvukala.

I-Emapalumab-lzsg iza njengoketshezi oluzofakwa emthanjeni ngaphezu kwehora elilodwa ngudokotela noma umhlengikazi esibhedlela noma esikhungweni sezokwelapha. Imvamisa inikezwa ama-2 ngesonto, njalo ezinsukwini ezi-3 noma ezi-4, inqobo nje uma udokotela wakho encoma ukuthi uthole ukwelashwa.

Udokotela wakho angakuqala ngomthamo ophansi womjovo we-emapalumab-lzsg bese ukhuphula kancane umthamo wakho, hhayi ngaphezu kwesisodwa njalo ezinsukwini ezi-3.

Umjovo we-Emapalumab-lzsg ungadala ukusabela okunzima ngesikhathi noma ngemuva nje kokufakwa komuthi. Udokotela noma umhlengikazi uzokuqapha ngokucophelela ngenkathi uthola umuthi. Uma uhlangabezana nalezi zimpawu ezilandelayo, tshela udokotela wakho ngokushesha: ukubomvu kwesikhumba, ukulunywa, umkhuhlane, ukuqubuka, ukujuluka ngokweqile, ukubanda, isicanucanu, ukuhlanza, ikhanda elikhanyayo, isiyezi, ubuhlungu besifuba, noma ukuphefumula okuncane.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa ngomjovo we-emapalumab-lzsg futhi isikhathi ngasinye lapho uthola umuthi. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) noma iwebhusayithi yomkhiqizi ukuthola i-Medication Guide.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola umjovo we-emapalumab-lzsg,

• Tshela udokotela kanye nosokhemisi wakho uma unegciwane kwi-emapalumab-lzsg, noma imuphi omunye umuthi, noma esinye isithako somjovo we-emapalumab-lzsg. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
• tshela udokotela wakho uma ngabe uke waba nesimo esithile sezempilo noma wake waba naso.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthola umjovo we-emapalumab-lzsg, shayela udokotela wakho.
• kufanele wazi ukuthi umjovo we-emapalumab-lzsg unganciphisa ikhono lakho lokulwa nokutheleleka okuvela kuma-bacteria, amagciwane, nesikhunta futhi kwandise ingozi yokuthi uzothola ukutheleleka okuyingozi noma okusongela impilo. Tshela udokotela wakho uma uvame ukuthola noma yiluphi uhlobo lokutheleleka noma uma une noma ucabanga ukuthi ungahle ube nolunye uhlobo lokutheleleka manje. Lokhu kufaka ukutheleleka okuncane (njengokusikeka okuvulekile noma izilonda), izifo ezifika zidlule (njenge-herpes noma izilonda ezibandayo), kanye nezifo ezingapheli ezingapheli. Uma uhlangabezana nalezi zimpawu ezilandelayo ngesikhathi noma ngemuva nje kokwelapha kwakho ngomjovo we-emapalumab-lzsg, shayela udokotela wakho ngokushesha: umkhuhlane, ukujuluka, noma ukubanda; ubuhlungu bemisipha; ukukhwehlela; amafinyila anegazi; ukuphelelwa umoya; umphimbo obuhlungu noma ubunzima bokugwinya; isikhumba esifudumele, esibomvu, noma esibuhlungu noma izilonda emzimbeni wakho; isifo sohudo; ubuhlungu besisu; ukuchama kaningi, okuphuthumayo noma okubuhlungu; noma ezinye izimpawu zokutheleleka.
• kufanele wazi ukuthi ukuthola umjovo we-emapalumab-lzsg kwandisa ingozi yokuthi uzoba nesifo sofuba (i-TB; ukutheleleka okuyingozi kwamaphaphu), ikakhulukazi uma usuvele ungenwe yi-TB kodwa ungenazo izimpawu zesifo. Tshela udokotela wakho uma uke waba ne-TB noma wake waba nayo, uma ngabe uhlala ezweni lapho i-TB ijwayelekile khona, noma uma wake waba seduze komuntu one-TB. Udokotela wakho uzokuhlolela i-TB ngaphambi kokuqala ukwelashwa ngomjovo we-emapalumab-lzsg futhi angakwelapha i-TB uma unomlando we-TB noma une-TB esebenzayo. Uma unalezi zimpawu ezilandelayo ze-TB noma uma uba nalezi zimpawu phakathi nokwelashwa kwakho, shayela udokotela wakho ngokushesha: ukukhwehlela, ukukhwehlela igazi noma amafinyila, ubuthakathaka noma ukukhathala, ukuncipha komzimba, ukulahlekelwa isifiso sokudla, ukugodola, umkhuhlane, noma ukujuluka ebusuku.
• ungenayo imigomo ngaphandle kokukhuluma nodokotela wakho ngesikhathi sokwelashwa kwakho ngomjovo we-emapalumab-lzsg futhi okungenani amasonto ama-4 ngemuva komthamo wakho wokugcina.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Umjovo we-Emapalumab-lzsg ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ukuqunjelwa
• ukuphuma kwamakhala emakhaleni

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu noma lezo ezisohlwini lwe-HOW section kanye ne-SPECIAL PRECAUTIONS section, yeka ukuthatha umjovo we-emapalumab-lzsg bese ushayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukushaya kwenhliziyo okusheshayo, okuhamba kancane, noma okungajwayelekile
• ukuphefumula okusheshayo
• amajaqamba
• ukuba ndikindiki nokushoshozela
• ezinegazi noma ezimnyama, izitulo zokulinda
• ukuhlanza igazi noma okokusundu okufana nezindawo zekhofi
• ukuncipha kokuchama
• ukuvuvukala ezandleni, ezinyaweni, emaqakaleni, noma emilenzeni engezansi

Umjovo we-Emapalumab-lzsg ungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzohlola umfutho wegazi lakho njalo futhi uzo-oda izivivinyo ezithile zelebhu ngaphambi nangesikhathi sokwelashwa kwakho ngomjovo we-emapalumab-lzsg ukuhlola impendulo yomzimba wakho emithini.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Okuhle kakhulu^®