Erdafitinib

-Delile

• Ngaphambi kokuthatha i-erdafitinib,
• I-Erdafitinib ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, yeka ukuthatha i-erdafitinib bese ushayela udokotela wakho ngokushesha:

I-Erdafitinib isetshenziselwa ukwelapha umdlavuza we-urothelial (umdlavuza wendwangu yesinye nezinye izingxenye zomgudu womchamo) osakazeka ezicutshini eziseduze noma kwezinye izingxenye zomzimba ezingenakususwa ngokuhlinzwa futhi ziye zaba zimbi kakhulu ngesikhathi noma ngemuva kokuphathwa nezinye imithi yokwelashwa ngamakhemikhali. U-Erdafitinib usesigabeni semithi ebizwa nge-kinase inhibitors. Isebenza ngokuvimba isenzo sephrotheni engavamile ekhombisa ukuthi amangqamuzana omdlavuza ayanda. Lokhu kusiza ukunciphisa noma ukumisa ukusabalala kwamangqamuzana omdlavuza.

I-Erdafitinib iza njengethebhulethi ezothathwa ngomlomo. Imvamisa kuthathwa kanye ngosuku noma ngaphandle kokudla. Thatha i-erdafitinib ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-erdafitinib njengoba iqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Gwinya wonke amaphilisi; ungawahlukanisi, ungawahlafune noma uwagxoze.

Uma uhlanza ngemuva kokuthatha i-erdafitinib, ungathathi omunye umthamo. Qhubeka nesimiso sakho sokulinganisa okuvamile.

Udokotela wakho anganciphisa umthamo wakho noma ayeke ukwelashwa kwakho okwesikhashana noma unomphela uma uhlangabezana nemiphumela ethile emibi. Qiniseka ukuthi utshela udokotela wakho ukuthi uzizwa kanjani ngenkathi welashwa nge-erdafitinib. Ungayeki ukuthatha i-erdafitinib ngaphandle kokukhuluma nodokotela wakho.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-erdafitinib,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-erdafitinib, noma imuphi omunye umuthi, noma iziphi izithako ezikumaphilisi e-erdafitinib. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: ama-antifungal afana ne-fluconazole (Diflucan), itraconazole (Sporonox, Onmel, Tolsura), ne-ketoconazole; carbamazepine (Carbatrol, Equetro, Tegretol, abanye); i-clarithromycin; imishanguzo yegciwane lesandulela ngculazi (i-HIV) njenge-efavirenz (Sustiva, e-Atripla), indinavir (Crixivan), nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norvir, eKaletra, eViekira), nase-saquinavir (Fortovase, Invirase ); i-metformin (i-Fortamet, iGlucophage, e-Actoplus Met, abanye); nefazodone; i-phenobarbital; i-phenytoin (iDilantin, Phenytek;), i-rifampin (i-Rifadin, i-Rimactane, ku-Rifater); kanye ne-telithromycin (Ketek). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imithi eminingi ingahle ihlanganyele ne-erdafitinib, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho nalawo angaveli kulolu hlu.
• Tshela udokotela wakho uma wake watshelwa ukuthi unamazinga aphezulu egazi e-phosphorus noma uma uke waba nezinkinga zamehlo noma zokubona, noma isifo sezinso noma sesibindi.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uma uhlela ukuba ngubaba wengane. Uma ungowesifazane, kuzodingeka uthathe ukuhlolwa kokukhulelwa ngaphambi kokuqala ukwelashwa futhi usebenzise izilawuli zokubeletha ukuvimbela ukukhulelwa ngesikhathi sokwelashwa kwakho nenyanga eyodwa ngemuva komthamo wakho wokugcina. Uma ungowesilisa, wena nomlingani wakho kufanele nisebenzise ukulawulwa kokubeletha ngesikhathi sokwelashwa nge-erdafitinib kanye nenyanga e-1 ngemuva komthamo wakho wokugcina. Khuluma nodokotela wakho ngezindlela zokulawula ukubeletha ongazisebenzisa ngesikhathi sokwelashwa kwakho. Uma wena noma umlingani wakho ukhulelwa ngenkathi uthatha i-erdafitinib, shayela udokotela wakho ngokushesha. I-Erdafitinib ingalimaza umbungu.
• tshela udokotela wakho uma uncelisa. Akufanele uncelise ibele ngenkathi uthatha i-erdafitinib kanye nenyanga e-1 ngemuva komthamo wokugcina.
• kufanele wazi ukuthi lo muthi unganciphisa ukuzala kwabesifazane. Khuluma nodokotela wakho ngezingozi zokuthatha i-erdafitinib.
• kufanele wazi ukuthi lo muthi ungadala amehlo omile nezinye izinkinga zamehlo, ezingaba zimbi kakhulu.Udokotela wakho angakutshela ukuthi usebenzise izinyembezi zokufakelwa noma amathonsi wamehlo okugcoba ngenkathi welashwa nge-erdafitinib.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Uma ukhumbula umthamo ongabanjwanga ngosuku obekufanele uwuthathe, thatha isilinganiso esilahlekile ngokushesha nje lapho usikhumbula ngalolo suku. Kodwa-ke, uma ungawukhumbuli umthamo ophuthelwe kuze kube usuku olulandelayo, weqa umthamo ophuthelwe bese uqhubeka nesimiso sakho sokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Erdafitinib ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isicanucanu
• isifo sohudo
• ukuhlanza
• ukuqunjelwa
• izilonda ezindebeni, emlonyeni, noma emphinjeni
• umlomo owomile
• izinguquko ekunambithekeni
• ubuhlungu besisu
• ukuncipha kokudla
• ukuncipha komzimba
• ukuncipha kwezinwele okungavamile noma ukulahleka kwezinwele
• imfiva
• ubuhlungu bemisipha noma bamalunga
• ukuvutha ngesikhathi sokuchama
• ukukhathala noma ukukhathala
• ukuphelelwa umoya

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, yeka ukuthatha i-erdafitinib bese ushayela udokotela wakho ngokushesha:

• ukungaboni kahle, ukulahleka kombono, noma ezinye izinguquko ezibonakalayo
• izinkinga zezipikili noma izinguquko
• uluma, womile noma uqhekekile isikhumba
• ukuqubuka
• ukuvuvukala, ubuhlungu, ubomvu, noma ukuxebuka kwesikhumba ezintendeni zezandla nasematheni ezinyawo

I-Erdafitinib ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina konke ukubonana nodokotela wakho, udokotela wamehlo, kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ku-erdafitinib.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• IBalversa^®