I-Niacin ye-cholesterol

I-Niacin iyi-B-vitamin. Uma uthathwa njengomuthi kadokotela ngemithamo emikhulu, ungasiza ukwehlisa i-cholesterol namanye amafutha egazini lakho. I-Niacin iyasiza:

• Khulisa i-cholesterol ye-HDL (enhle)
• I-cholesterol ephansi ye-LDL (embi)
• Ama-triglycerides aphansi, olunye uhlobo lwamafutha egazini lakho

I-Niacin isebenza ngokuvimba ukuthi isibindi sakho senza kanjani i-cholesterol. I-cholesterol inganamathela ezindongeni zemithambo yakho bese iyancipha noma iyivimbe.

Ukwenza ngcono amazinga akho e-cholesterol kungasiza ukukuvikela kusuka:

• Isifo senhliziyo
• Isifo senhliziyo
• Unhlangothi

Umhlinzeki wakho wokunakekelwa kwezempilo uzosebenza nawe ukwehlisa i-cholesterol yakho ngokuthuthukisa indlela odla ngayo. Uma lokhu kungaphumeleli, imithi yokwehlisa i-cholesterol ingaba yisinyathelo esilandelayo. Izitatimende kucatshangwa ukuthi yimithi engcono kakhulu ongayisebenzisa kubantu abadinga imithi yokwehlisa i-cholesterol yabo.

Ucwaningo manje luphakamisa ukuthi i-niacin ayengezi ekusizeni kwesitatimende kuphela sokunciphisa ubungozi bemicimbi yenhliziyo, kufaka phakathi isifo senhliziyo nokushaywa yisifo sohlangothi.

Ngaphezu kwalokho, i-niacin ingadala imiphumela engemihle futhi engaba yingozi. Ngakho-ke, ukusetshenziswa kwayo bekulokhu kwehla. Kodwa-ke, abanye abantu bangabekwa i-niacin ngaphezu kweminye imishanguzo uma bane-cholesterol ephezulu kakhulu noma uma bengayibekezeleli eminye imithi.

Kunezinhlobo ezahlukahlukene zemithi ye-niacin. Eziningi zalezi futhi ziza ngendlela engabizi kakhulu, ejwayelekile.

I-Niacin ingahle ibhalwe kanye neminye imithi, njenge-statin, ukusiza ukwehlisa i-cholesterol. Amaphilisi enhlanganisela afaka i-nicotinic acid kanye neminye imithi ayatholakala.

INiacin ibuye ithengiswe ngaphezu kwe-the-counter (i-OTC) njengesengezo. Akufanele uthathe i-OTC niacin ukusiza ukwehlisa i-cholesterol. Ukwenza kanjalo kungaba nemiphumela emibi kakhulu.

Thatha umuthi wakho njengokuyalelwa. Umuthi uza kwifomu yethebhulethi. Ungaphuli noma uhlafune amaphilisi ngaphambi kokuthatha umuthi. Ungayeki ukuthatha umuthi wakho ngaphandle kokukhuluma nomhlinzeki wakho kuqala.

Uthatha i-niacin izikhathi ezi-1 ukuya kwezi-3 ngosuku. Iza ngamanani ahlukene, kuya ngokuthi udinga malini.

Funda ilebula elisebhodleleni lephilisi ngokucophelela. Eminye imikhiqizo kufanele ithathwe ngesikhathi sokulala ngesikhwama esincane, esinamafutha amancane; ezinye uzothatha nesidlo sakusihlwa. Gwema utshwala neziphuzo ezishisayo ngenkathi uthatha i-niacin ukunciphisa ukuqhuma.

Gcina yonke imithi yakho endaweni epholile, eyomile. Zigcine lapho izingane zingakwazi ukufinyelela kuzo.

Kufanele ulandele ukudla okunempilo ngenkathi uthatha i-niacin. Lokhu kufaka phakathi ukudla amafutha amancane ekudleni kwakho. Ezinye izindlela ongasiza ngazo inhliziyo yakho zifaka:

• Ukuvivinya umzimba njalo
• Ukulawula ukucindezeleka
• Ukuyeka ukubhema

Ngaphambi kokuba uqale ukuthatha i-niacin, tshela umhlinzeki wakho uma:

• Ukhulelwe, hlela ukukhulelwa, noma ukuncelisa
• Unomzimba ongezwani nawo
• Bathatha eminye imithi
• Phuza kakhulu utshwala
• Unesifo sikashukela, isifo sezinso, i-peptic ulcer, noma i-gout

Khuluma nomhlinzeki wakho ngayo yonke imithi yakho, amakhambi, noma izithasiselo. Imithi ethile ingaxhumana ne-niacin.

Ukuhlolwa kwegazi njalo kuzokusiza wena nomhlinzeki wakho:

• Bona ukuthi umuthi usebenza kahle kanjani
• Ukuqapha imiphumela emibi, njengezinkinga zesibindi

Imiphumela emibi ethambile ingafaka:

• Ukuqhuma nokubomvu ubuso noma intamo
• Uhudo
• Ubuhlungu bekhanda
• Isisu esibuhlungu
• Ukuqhuma kwesikhumba

Yize kungavamile, imiphumela emibi kakhulu ingenzeka. Umhlinzeki wakho uzokuqapha ngezimpawu. Khuluma nomhlinzeki wakho ngalezi zingozi ezingenzeka:

• Ukulimala kwesibindi kanye nezinguquko kuma-enzyme wesibindi
• Ubuhlungu obukhulu bemisipha, ubumnene, nobuthakathaka
• Ukushaya kwenhliziyo nesigqi kuyashintsha
• Izinguquko kumfutho wegazi
• Ukuqhuma okukhulu, ukuqubuka kwesikhumba, nokushintsha kwesikhumba
• Ukungabekezelelani kwe-glucose
• Gout
• Ukulahleka kombono noma izinguquko

Kufanele ushayele umhlinzeki wakho uma uqaphela:

• Imiphumela emibi ekuhluphayo
• Ukuquleka
• Isiyezi
• Ukushaya kwenhliziyo okusheshayo noma okungajwayelekile
• Isikhumba esiphuzi noma amehlo (i-jaundice)
• Ubuhlungu bemisipha nobuthakathaka
• Ezinye izimpawu ezintsha

Ummeli we-Antilipemic; Uvithamini B3; I-Nicotinic acid; I-Niaspan; I-Niacor; I-Hyperlipidemia - niacin; Ukuqina kwemithambo yegazi - i-niacin; Icholesterol - niacin; Hypercholesterolemia - niacin; I-dyslipidemia - i-niacin

Iwebhusayithi yeAmerican Heart Association. Imithi ye-cholesterol. www.heart.org/en/health-topics/cholesterol/prevention-and-treatment-of-high-cholesterol-hyperlipidemia/cholesterol-medications. Kubuyekezwe ngoNovemba 10, 2018. Kufinyelelwe ngoMashi 4, 2020.

UGenest J, ukuphazamiseka kweLibby P. Lipoprotein nesifo senhliziyo. Ku: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, ama-eds. Isifo Senhliziyo SikaBraunwald: Incwadi Yemithi Yezinhliziyo Nemithambo. Umhla ka-11. IPhiladelphia, PA: Elsevier; 2019: isahluko 48.

I-Grundy SM, i-Stone NJ, i-Bailey AL, et al. 2018 AHA / ACC / AACVPR / AAPA / ABC / ACPM / ADA / AGS / APhA / ASPC / NLA / PCNA umhlahlandlela wokuphathwa kwe-cholesterol yegazi: umbiko we-American College of Cardiology / American Heart Association Task Force on Guidelines Practice Guidelines . UJ Am Coll Cardiol. 2019; 73 (24): e285 – e350. I-PMID: 30423393 pubmed.ncbi.nlm.nih.gov/30423393/.

UGuyton JR, uMcGovern ME, uCarlson LA. I-Niacin (i-nicotinic acid). Ku: Ballantyne CM, ed. I-Clinical Lipidology: Umngane Wesifo Senhliziyo SaseBraunwald. Okwesibili. IPhiladelphia, PA: Elsevier Saunders; 2015: isahluko 24.

UNdunankulu waseLavigne, uKaras RH. Isimo samanje se-niacin ekuvimbeleni izifo zenhliziyo: ukubuyekezwa okuhlelekile kanye ne-meta-regression. UJ Am Coll Cardiol. 2013; 61 (4): 440-446. I-PMID: 23265337 pubmed.ncbi.nlm.nih.gov/23265337/.

UMani P, Rohatgi A. Ukwelashwa kwe-Niacin, i-cholesterol ye-HDL, nesifo senhliziyo: ingabe i-HDL hypothesis ayisebenzi? I-Curr Atheroscler Rep. 2015,17 (8): 43. I-PMID: 26048725 pubmed.ncbi.nlm.nih.gov/26048725/.

• B Amavithamini
• Cholesterol
• Imithi Ye-cholesterol
• I-HDL: I-cholesterol "Enhle"
• I-LDL: I-cholesterol "Engalungile"