Umlobi: William Ramirez
Usuku Lokudalwa: 20 Usepthemba 2021
Ukuvuselela Usuku: 13 Unovemba 2024
Anonim
Risankizumab shows promise for PsA in the KEEPsAKE 2 trial | Andrew Ostor
Ividiyo: Risankizumab shows promise for PsA in the KEEPsAKE 2 trial | Andrew Ostor

-Delile

Umjovo we-Risankizumab-rzaa usetshenziselwa ukwelapha i-plaque psoriasis esesilinganisweni (isifo sesikhumba lapho kwakhiwa khona amabala abomvu, anezikhala ezindaweni ezithile zomzimba) kubantu abadala abane-psoriasis ebucayi kakhulu ukuthi ingalashwa ngemithi yokwelapha kuphela. I-Risankizumab-rzaa isekilasini lemithi ebizwa ngama-antibody monoclonal. Isebenza ngokumisa ukusebenza kwamaseli athile emzimbeni adala izimpawu ze-psoriasis.

I-Risankizumab-rzaa iza njengesisombululo esiringeni esivele safakwa ukuze ujovwe ngomgogodla (ngaphansi kwesikhumba). Imvamisa inikezwa njengemijovo emibili yomthamo wokuqala, ilandelwe imijovo emibili emavikini ama-4 ngemuva kwesilinganiso sokuqala, bese kuba imijovo emibili njalo emavikini ayi-12. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Sebenzisa umjovo we-risankizumab-rzaa njengoba uqondisiwe. Ungayifaki ngaphezulu noma ngaphansi kwayo noma uyijoje kaningi kunokuyalelwa ngudokotela wakho.

Ungathola umthamo wakho wokuqala womjovo we-risankizumab-rzaa ehhovisi likadokotela wakho. Ngemuva komthamo wakho wokuqala, udokotela wakho angakuvumela noma umnakekeli enze imijovo ekhaya. Buza udokotela wakho noma usokhemisi ukuthi akubonise noma umuntu ozobe ejova umuthi ukuthi ungawujova kanjani.


Ungafaka umjovo we-risankizumab-rzaa noma yikuphi ngaphambili kwamathanga akho (umlenze ongaphezulu) noma isisu (isisu) ngaphandle kwenkaba yakho nendawo engamasentimitha ama-5 ukuyizungeza. Uma omunye umuntu ekujova, lowo muntu angajova umuthi ezingalweni zakho ezingaphezulu, zangaphandle. Sebenzisa isiza esihlukile ngomjovo ngamunye ukunciphisa amathuba okuba buhlungu noma okubomvu. Ungafaki endaweni lapho isikhumba sithambile, silimele, sibomvu, noma siqinile noma lapho unezibazi noma izimpawu zokwelula.

Unganyakazisi isirinji equkethe i-risankizumab-rzaa.

Uma usebenzisa isirinji ekhethiwe efrijiwe, beka isirinji endaweni eyisicaba ngaphandle kokukhipha isigaxa senaliti bese uyivumela ifudumele ekamelweni lokushisa imizuzu eyi-15 kuya kwengama-30 ngaphambi kokuba ulungele ukujova umuthi.

Njalo bheka isisombululo se-risankizumab-rzaa ngaphambi kokusijova. Bheka ukuthi usuku lokuphelelwa yisikhathi aludlulanga nokuthi uketshezi alunambala ukuze luphuzi kancane futhi licace. Uketshezi akufanele luqukethe izinhlayiya ezibonakalayo. Ungayisebenzisi isipontsho uma siqhekekile noma siphukile, uma siwile, uma siphelelwe yisikhathi, noma uma uketshezi lunamafu noma luqukethe izinhlayiya ezinkulu noma ezinemibala.


Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa ngomjovo we-risankizumab-rzaa. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokusebenzisa umjovo we-risankizumab-rzaa

  • Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-risankizumab-rzaa, noma imuphi omunye umuthi, noma iziphi izithako ezise-risankizumab-rzaa. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
  • Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
  • utshele udokotela wakho uma uke waba nezinye izimo zezokwelapha noma wake waba nazo.
  • utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi usebenzisa umjovo we-risankizumab-rzaa, shayela udokotela wakho.
  • thintana nodokotela wakho ukuze ubone uma ngabe udinga ukuthola noma yimiphi imigomo. Kubalulekile ukuthi yonke imishanguzo yokugoma ilungele iminyaka yakho ngaphambi kokuqala ukwelashwa kwakho ngomjovo we-risankizumab-rzaa. Ungabi nayo imigomo ngesikhathi sokwelashwa kwakho ngaphandle kokukhuluma nodokotela wakho.
  • kufanele wazi ukuthi umjovo we-risankizumab-rzaa unganciphisa ikhono lakho lokulwa nokutheleleka kusuka kuma-bacteria, amagciwane, nesikhunta futhi kwandise ingozi yokuthi uzothola ukutheleleka okuyingozi noma okusongela impilo. Tshela udokotela wakho uma uvame ukuthola noma yiluphi uhlobo lokutheleleka noma uma une noma ucabanga ukuthi ungahle ube nolunye uhlobo lokutheleleka manje. Lokhu kufaka ukutheleleka okuncane (njengokusikeka okuvulekile noma izilonda), izifo ezifika zidlule (njenge-herpes noma izilonda ezibandayo), kanye nezifo ezingapheli ezingapheli. Uma uhlangabezana nalezi zimpawu ezilandelayo ngesikhathi noma ngemuva nje kokwelapha kwakho ngomjovo we-risankizumab-rzaa, shayela udokotela wakho ngokushesha: umkhuhlane, ukujuluka, noma ukubanda, izinhlungu zemisipha, ukuphefumula, ukufudumala, obomvu, noma isikhumba esibuhlungu noma izilonda umzimba, ukwehla kwesisindo, isifo sohudo, ubuhlungu besisu, ukuchama kaningi, okuphuthumayo noma okubuhlungu, noma ezinye izimpawu zokutheleleka.
  • kufanele wazi ukuthi ukusebenzisa umjovo we-risankizumab-rzaa kwandisa ubungozi bokuthi uzoba nesifo sofuba (i-TB; isifo esibucayi samaphaphu), ikakhulukazi uma usuvele ungenwe yisifo sofuba kodwa ungenazo izimpawu zesifo. Tshela udokotela wakho uma uke waba ne-TB noma wake waba nayo, uma ngabe uhlala ezweni lapho i-TB ijwayelekile khona, noma uma wake waba seduze komuntu one-TB. Udokotela wakho uzokuhlolela isikhumba ukuze abone ukuthi une-TB engasebenzi yini. Uma kunesidingo, udokotela wakho uzokunika imithi yokwelapha lesi sifo ngaphambi kokuqala ukusebenzisa umjovo we-risankizumab-rzaa. Uma unezinye zalezi zimpawu ezilandelayo ze-TB, noma uma uba nalezi zimpawu phakathi nokwelashwa kwakho, shayela udokotela wakho ngokushesha: ukukhwehlela, ubuhlungu besifuba, ukukhwehlela igazi noma amafinyila, ubuthakathaka noma ukukhathala, ukwehla kwesisindo, ukungathandi ukudla, Ukugodola, umkhuhlane, noma ukujuluka ebusuku.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.


Uma umthamo ungabanjwanga, jovula umthamo ngokushesha okukhulu bese unika umjovo olandelayo ngesikhathi esihleliwe esijwayelekile. Ungasebenzisi umthamo ophindwe kabili ukwenza okulahlekile.

Umjovo we-Risankizumab-rzaa ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

  • ikhanda
  • ikhala eligobayo, umphimbo obuhlungu, ukuthimula, noma isiminyaminya samakhala
  • ukukhathala ngokweqile
  • ukulinyazwa kwesiza somjovo, ubuhlungu, ububomvu, ukuvuvukala, ukucasuka, ubuhlungu, ukulunywa nokufudumala

Umjovo we-Risankizumab-rzaa ungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi usebenzisa lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina umjovo we-risankizumab-rzaa esiqandisini kodwa ungafrizi.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho.

Ungavumeli omunye umuntu asebenzise imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

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Kugcine ukubuyekezwa - 06/15/2019

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