Inaliti yeTrastuzumab neHyaluronidase-oysk

-Delile

• Ngaphambi kokuthola umjovo we-trastuzumab ne-hyaluronidase-oysk,
• Umjovo we-Trastuzumab ne-hyaluronidase-oysk ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:

Umjovo weTrastuzumab ne-hyaluronidase-oysk ungadala izinkinga zenhliziyo ezinkulu noma ezisongela impilo. Tshela udokotela wakho uma uke waba nesifo senhliziyo noma wake waba naso. Udokotela wakho uzoku-oda ukuhlolwa ngaphambi nangesikhathi sokwelashwa kwakho ukuze abone ukuthi inhliziyo yakho isebenza kahle ngokwanele yini ukuthola umjovo we-trastuzumab ne-hyaluronidase-oysk. Tshela udokotela kanye nosokhemisi wakho uma welashwa ngemithi ye-anthracycline yomdlavuza efana ne-daunorubicin (Cerubidine), doxorubicin (Doxil), epirubicin (Ellence), ne-idarubicin (Idamycin). Udokotela wakho uzodinga ukukuqapha eduze uma uthola le mithi ngesikhathi sokwelashwa kwakho ngomjovo we-trastuzumab ne-hyaluronidase-oysk futhi kuze kube izinyanga eziyisi-7 ngemuva komthamo wakho wokugcina. Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: ukukhwehlela; ukuphelelwa umoya; ukuvuvukala kwezingalo, izandla, izinyawo, amaqakala noma imilenze engezansi; ukukhuluphala (ngaphezu kwamakhilogremu ama-5 [cishe ama-2.3 kilograms] ngamahora angama-24); isiyezi; ukulahlekelwa ukwazi; noma ukushaya kwenhliziyo okusheshayo, okungajwayelekile, noma okushaya ngamandla.

Umjovo we-Trastuzumab ne-hyaluronidase-oysk ungadala ukusabela okunamandla noma okusongela impilo okungenzeka ngenkathi kunikezwa umuthi noma kufika emahoreni angama-24 ngemuva komthamo. Umjovo we-Trastuzumab ne-hyaluronidase-oysk nawo ungadala umonakalo omkhulu wamaphaphu. Tshela udokotela wakho uma uke waba nesifo samaphaphu noma wake waba nesifo emaphashini, ikakhulukazi uma sikudalile ukuthi uphefumule kanzima. Udokotela wakho uzokubuka ngokucophelela lapho uthola umjovo we-trastuzumab ne-hyaluronidase-oysk ukuze ukwelashwa kwakho kuphazamiseke uma uhlangabezana nokusabela okungathi sína. Uma unezinye zalezi zimpawu ezilandelayo, tshela udokotela wakho ngokushesha: umkhuhlane; Ukugodola; isicanucanu; ukuhlanza; isifo sohudo; ubuhlungu besifuba; ikhanda; isiyezi; ubuthakathaka; ukuqubuka; isifuba; ukulunywa; ukuvuvukala kobuso, amehlo, umlomo, umphimbo, ulimi, noma izindebe; noma ukuphefumula kanzima noma ukugwinya.

Tshela udokotela wakho uma ukhulelwe noma uhlela ukukhulelwa. Umjovo weTrastuzumab ne-hyaluronidase-oysk ungalimaza ingane yakho engakazalwa. Kufanele usebenzise ukulawulwa kokubeletha ukuvimbela ukukhulelwa ngesikhathi sokwelashwa kwakho nezinyanga eziyi-7 ngemuva komthamo wakho wokugcina. Khuluma nodokotela wakho ngezindlela zokulawula ukubeletha ezizokusebenzela. Uma ukhulelwa ngesikhathi sokwelashwa kwakho ngomjovo we-trastuzumab ne-hyaluronidase-oysk, shayela udokotela wakho ngokushesha.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile ukuze ahlole impendulo yomzimba wakho kumjovo we-trastuzumab ne-hyaluronidase-oysk.

Khuluma nodokotela wakho ngezingozi zokuthola umjovo we-trastuzumab ne-hyaluronidase-oysk.

Umjovo we-Trastuzumab ne-hyaluronidase-oysk usetshenziswa kanye neminye imithi noma ngemuva kokuthi eminye imithi isivele isetshenziselwe ukwelapha uhlobo oluthile lomdlavuza webele oselusabalele kwezinye izingxenye zomzimba. Umjovo we-Trastuzumab ne-hyaluronidase-oysk nawo uyasetshenziswa ngesikhathi nangemva kokwelashwa neminye imithi ukunciphisa amathuba okuthi uhlobo oluthile lomdlavuza webele lubuye. Umjovo weTrastuzumab ne-hyaluronidase-oysk usekilasini lemithi ebizwa ngama-antibody monoclonal. Isebenza ngokumisa ukukhula kwamangqamuzana omdlavuza.

Umjovo weTrastuzumab ne-hyaluronidase-oysk uza njengoketshezi oluzofakwa ngaphansi kwesikhumba ethangeni ngaphezulu kwemizuzu emi-2 kuye kwemihlanu. Umjovo weTrastuzumab ne-hyaluronidase-oysk unikezwa udokotela noma umhlengikazi esibhedlela noma esikhungweni sezokwelapha. Imvamisa inikezwa kanye njalo emavikini ama-3. Ubude bokwelashwa kwakho buzoncika esimweni onaso nokuthi umzimba wakho uphendula kahle kangakanani ekwelashweni.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola umjovo we-trastuzumab ne-hyaluronidase-oysk,

• Tshela udokotela wakho kanye nosokhemisi uma une-aleji ku-trastuzumab, i-hyaluronidase (i-Amphadase, i-Vitrase), noma imiphi eminye imithi, noma iziphi izithako zomjovo we-trastuzumab ne-hyaluronidase-oysk.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi uyayisho imishanguzo ebhalwe esigabeni ESIBALULEKILE SEXWAYISO, ikakhulukazi uma uyithola kungakapheli izinyanga eziyi-7 umise umjovo we-trastuzumab ne-hyaluronidase-oysk. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• utshele udokotela wakho uma ngabe uke waba nanoma yimiphi imibandela eshiwo esigabeni ESIBALULEKILE SEXWAYISO noma esinye isimo sezokwelapha.
• tshela udokotela wakho uma uncelisa.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi uthola umjovo we-trastuzumab ne-hyaluronidase-oysk.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Shayela udokotela wakho ngokushesha uma ungakwazi ukugcina i-aphoyintimenti yokuthola umthamo we-trastuzumab ne-hyaluronidase-oysk injection.

Umjovo we-Trastuzumab ne-hyaluronidase-oysk ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isifo sohudo
• ukuqunjelwa
• ubuhlungu besisu
• isilungulela
• ukulahlekelwa isifiso sokudla
• izinguquko ekunambithekeni
• izilonda zomlomo
• ubuhlungu bengalo, umlenze, iqolo, ithambo, amalunga noma imisipha
• ubuhlungu noma ububomvu endaweni lapho umjovo wafakwa khona
• ukulahleka kwezinwele
• ubunzima bokulala noma ukulala
• ukushisa okushisayo
• ukuba ndikindiki, ukushiswa, noma ukuncinza ezingalweni, ezandleni, ezinyaweni noma emilenzeni
• izinguquko ekubukekeni kwezipikili
• induna
• ukudana

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:

• umphimbo obuhlungu, umkhuhlane, amakhaza, ukuchama okunzima noma okubuhlungu, nezinye izimpawu zokutheleleka
• ukuphuma kwamakhala noma okunye ukulimaza noma ukopha okungavamile
• ukukhathala ngokweqile
• isikhumba esiphaphathekile
• isicanucanu; ukuhlanza; ukulahlekelwa ukudla; ukukhathala; ukushaya kwenhliziyo okusheshayo; umchamo omnyama; ukuncipha kwenani lomchamo; ubuhlungu besisu; ukuquleka; ukusangana; noma amajaqamba kanye nama-spasms

Umjovo we-Trastuzumab ne-hyaluronidase-oysk ungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthola lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nomjovo we-trastuzumab ne-hyaluronidase-oysk.

Udokotela wakho uzoku-oda ukuhlolwa kwelebhu ngaphambi kokuba uqale ukwelashwa kwakho ukuze ubone ukuthi umdlavuza wakho ungelashwa nge-trastuzumab ne-hyaluronidase-oysk.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• UHerceptin Hylecta^®