Istradefylline

-Delile

• Ngaphambi kokuthatha i-istradefylline,
• Istradefylline ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

Istradefylline isetshenziswa kanye nenhlanganisela ye-levodopa ne-carbidopa (iDuopa, iRytary, iSinemet, nezinye) ukwelapha iziqephu "zokuvala" (izikhathi zobunzima bokuhamba, ukuhamba nokukhuluma okungenzeka njengoba umuthi uphela noma ungahleliwe) kubantu abane Isifo sikaParkinson (PD; ukuphazamiseka kwesistimu yezinzwa okubangela ubunzima ngokunyakaza, ukulawula imisipha, nokulinganisela). Istradefylline ikusigaba semithi esibizwa ngama-adenosine receptor antagonists. Isebenza ngokushintsha ukusebenza kwezinto ezithile zemvelo ebuchosheni.

Istradefylline iza njengethebhulethi ezothathwa ngomlomo. Imvamisa kuthathwa noma ngaphandle kokudla kanye ngosuku. Thatha i-istradefylline ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-istradefylline njengoba nje kuqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-istradefylline,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-istradefylline, noma imiphi eminye imithi, noma iziphi izithako ezikumaphilisi e-istradefylline. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: i-clarithromycin (i-Biaxin, e-Prevpac); ezinye izinto zokuvikela ezifana ne-itraconazole (i-Onmel, i-Sporanox) noma i-ketoconazole; i-digoxin (i-Lanoxin), i-enzalutamide (i-Xtandi); imishanguzo ethile yegciwane lesandulela-ngculazi (i-HIV) noma i-immunodeficiency syndrome (i-AIDS) efana ne-efavirenz (Sustiva, e-Atripla), indinavir (Crixivan), nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norvir, e Kaletra), kanye i-saquinavir (i-Invirase); i-modafinil (i-Provigil); nefazodone; i-pioglitazone (Actos, eDuetact, e-Oseni); i-rifabutin (i-Mycobutin); i-rifampin (i-Rifadin); imithi ethile yokuquleka efana ne-carbamazepine (Equetro, Tegretol, Teril), oxcarbazepine (Trileptal), phenobarbital, ne-phenytoin (Dilantin, Phenytek); i-steroids yomlomo efana ne-dexamethasone, i-methylprednisolone (Medrol), ne-prednisone; noma i-telithromycin (Ketek). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imithi eminingi ingase futhi ihlanganyele ne-istradefylline, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu.
• utshele udokotela wakho kanye nosokhemisi ukuthi yimiphi imikhiqizo yamakhambi oyithathayo, ikakhulukazi iSort John's wort. Akufanele uthathe i-wort yaseSt.John ngesikhathi sokwelashwa kwakho nge-istradefylline.
• Tshela udokotela wakho uma uke waba nesifo sokuphazamiseka kwengqondo (isimo esidala ubunzima bokutshela umehluko phakathi kwezinto noma imibono engokoqobo nezinto noma imibono engeyona engokoqobo), ukunyakaza komzimba ongeke ukwazi ukukulawula, noma isifo sesibindi.
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Akufanele ukhulelwe ngenkathi uthatha i-istradefylline. Kufanele usebenzise ukulawulwa kokubeletha okusebenzayo ukuvimbela ukukhulelwa ngesikhathi sokwelashwa kwakho nge-istradefylline. Uma ukhulelwa ngenkathi uthatha i-istradefylline, shayela udokotela wakho.
• utshele udokotela wakho uma usebenzisa imikhiqizo kagwayi (osikilidi, osikilidi, ugwayi wepayipi, noma ugwayi we-hookah [wepayipi lamanzi]. Ukubhema imikhiqizo kagwayi kunganciphisa ukusebenza kwalo muthi.
• kufanele wazi ukuthi abanye abantu abathathe imishanguzo efana ne-istradefylline baba nezinkinga zokugembula noma ezinye izifiso ezinkulu noma isimilo ebesibaphoqa noma singavamile kubo, njengokukhuphuka kwezifiso zocansi noma isimilo, ukusetshenziswa kwemali okungalawulwa, noma ukuzitika ngotshwala noma ukudla okuphoqayo. Shayela udokotela wakho uma unesifiso sokugembula okunzima ukusilawula, unezikhalazo ezinkulu, noma awukwazi ukulawula ukuziphatha kwakho. Tshela amalungu omndeni wakho ngale ngozi ukuze bakwazi ukubiza udokotela noma ngabe awuboni ukuthi ukugembula kwakho noma yiziphi ezinye izifiso ezinamandla noma ukuziphatha okungajwayelekile kube yinkinga.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

Istradefylline ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isiyezi
• ukuqunjelwa
• ukulahlekelwa isifiso sokudla
• ubunzima bokulala noma ukulala

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukunyuka komzimba noma ukunyakaza komzimba okuvame kakhulu ongakwazi ukukulawula
• ukusangana (ukubona izinto noma ukuzwa amazwi angekho)
• ukusola ngokweqile noma ukuzwa ukuthi abantu bafuna ukukulimaza
• ukukholwa izinto ezingezona ezangempela
• isimilo esinolaka, ukudinwa, noma ukudideka

Istradefylline ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Nourianz^®