I-Daunorubicin

-Delile

• Ngaphambi kokuthola umjovo we-daunorubicin,
• I-Daunorubicin ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:

Umjovo weDaunorubicin kufanele unikezwe esibhedlela noma esikhungweni sezokwelapha ngaphansi kweso lodokotela onolwazi lokunikeza imishanguzo yokwelashwa ngamakhemikhali yomdlavuza.

IDaunorubicin ingadala izinkinga zenhliziyo ezinkulu noma ezisongela impilo nganoma yisiphi isikhathi phakathi nokwelashwa kwakho noma izinyanga kuya eminyakeni ngemuva kokuphela kokwelashwa kwakho. Udokotela wakho uzo-oda ukuhlolwa ngaphambi nangesikhathi sokwelashwa kwakho ukuze abone ukuthi inhliziyo yakho isebenza kahle ngokwanele yini ukuthola i-daunorubicin ngokuphepha. Lezi zivivinyo zingafaka i-electrocardiogram (ECG; ukuhlolwa okurekhoda umsebenzi kagesi wenhliziyo) kanye ne-echocardiogram (ukuhlolwa okusebenzisa amaza omsindo ukukala amandla enhliziyo yakho okumpompa igazi). Udokotela wakho angakutshela ukuthi akufanele uthole le mithi uma izivivinyo zibonisa ukuthi amandla enhliziyo yakho okupompa igazi anciphile. Tshela udokotela wakho uma ngabe uke waba nanoma yiluphi uhlobo lwesifo senhliziyo noma ukwelashwa ngemisebe (x-ray) endaweni yesifuba. Tshela udokotela wakho kanye nosokhemisi uma uthatha noma wake wathola imithi ethile yokwelashwa ngamakhemikhali efana ne-doxorubicin (Doxil), i-epirubicin (Ellence), idarubicin (Idamycin), noma i-mitoxantrone (i-Novantrone), i-cyclophosphamide (i-Cytoxan), noma i-trastuzumab (i-Herceptin) . Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: ukuphefumula okuncane; ukuphefumula kanzima; ukuvuvukala kwezandla, izinyawo, amaqakala noma imilenze engezansi; noma ukushaya kwenhliziyo okusheshayo, okungajwayelekile, noma okushaya ngamandla.

IDaunorubicin ingadala ukwehla okukhulu kwenani lamaseli egazi emnkantsheni wakho. Lokhu kungadala izimpawu ezithile futhi kungakhuphula ubungozi bokuthi uzoba nokutheleleka okungathi sína noma ukopha. Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: umkhuhlane, umphimbo obuhlungu, ukukhwehlela okuqhubekayo nokuminyana, noma ezinye izimpawu zokutheleleka; ukopha okungavamile noma ukulinyazwa.

Tshela udokotela wakho uma uke waba nesifo sezinso noma sesibindi. Udokotela wakho angadinga ukulungisa umthamo wakho uma unesifo sezinso noma sesibindi.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile ukuze ahlole impendulo yomzimba wakho ku-daunorubicin.

I-Daunorubicin isetshenziswa neminye imithi yokwelapha ngamakhemikhali ukwelapha uhlobo oluthile lwe-acute myeloid leukemia (AML; uhlobo lomdlavuza wamaseli amhlophe egazi). IDaunorubicin iyasetshenziswa nezinye izidakamizwa zokwelapha ngamakhemikhali ukwelapha uhlobo oluthile lwe-acute lymphocytic leukemia (BONKE; uhlobo lomdlavuza wamaseli amhlophe egazi). IDaunorubicin isekilasini lemithi ebizwa ngama-anthracyclines. Isebenza ngokunciphisa noma ukumisa ukukhula kwamangqamuzana omdlavuza emzimbeni wakho.

IDaunorubicin iza njengesisombululo (uketshezi) noma njengempuphu ezohlanganiswa noketshezi oluzofakwa ngaphakathi (emthanjeni) ngudokotela noma umhlengikazi endaweni yezokwelapha kanye neminye imithi yokwelashwa ngamakhemikhali. Lapho i-daunorubicin isetshenziselwa ukwelapha i-AML, ivame ukujova kanye ngosuku ngezinsuku ezithile zesikhathi sakho sokwelashwa. Lapho i-daunorubicin isetshenziselwa ukwelapha KONKE, ivame ukujova kanye ngesonto. Ubude bokwelashwa buxhomeke ezinhlotsheni zemithi oyiphuzayo, ukuthi umzimba wakho uphendula kahle kangakanani kuyo, nohlobo lomdlavuza onawo.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola umjovo we-daunorubicin,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-daunorubicin, noma imiphi eminye imithi, noma yiziphi izithako zomjovo we-daunorubicin. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi uyayisho imishanguzo ebhalwe esigabeni ESIBALULEKILE SESEXWAYISO nakokulandelayo: azathioprine (Imuran), cyclosporine (Neoral, Sandimmune), methotrexate (Rheumatrex, Trexall), sirolimus (Rapamune), ne-tacrolimus (Prograf). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo nayo ingaxhumana ne-daunorubicin, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu.
• tshela udokotela wakho uma ngabe uke waba nesimo esithile sezempilo noma wake waba naso.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Akufanele ukhulelwe ngenkathi uthola umjovo we-daunorubicin. Uma ukhulelwa ngenkathi uthola i-daunorubicin, shayela udokotela wakho. I-Daunorubicin ingalimaza umbungu.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

I-Daunorubicin ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isicanucanu
• ukuhlanza
• izilonda emlonyeni nasemphinjeni
• isifo sohudo
• ubuhlungu besisu
• ukulahleka kwezinwele
• umchamo obomvu

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:

• ububomvu, ubuhlungu, ukuvuvukala, noma ukushisa endaweni lapho umjovo wanikezwa khona
• ukuqubuka
• isifuba
• ukulunywa
• ukuphefumula kanzima noma ukugwinya

IDaunorubicin ingakhuphula ubungozi bokuthi uzoba neminye imidlavuza. Khuluma nodokotela wakho ngezingozi zokuthatha lo muthi.

I-Daunorubicin ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Cerubidine^®

• Daunomycin
• I-Rubidomycin