I-Tamoxifen

-Delile

• Ngaphambi kokuthatha i-tamoxifen,
• I-Tamoxifen ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalezi zimpawu ezilandelayo noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka:

I-Tamoxifen ingadala umdlavuza wesibeletho (isibeletho), unhlangothi, namahlule egazini emaphashini. Lezi zimo zingaba zimbi noma zibulale. Tshela udokotela wakho uma ngabe uke waba negazi emaphashini noma emilenzeni, isifo sohlangothi noma isifo senhliziyo. Phinda utshele udokotela wakho uma ubhema, uma unengcindezi ephezulu yegazi noma isifo sikashukela, uma amandla akho okuzula phakathi namahora akho okuvuka alinganiselwe, noma uma uthatha ama-anticoagulants ('ama-thinner egazi') njenge-warfarin (Coumadin). Uma uhlangabezana nalezi zimpawu ezilandelayo ngesikhathi sokwelashwa kwakho noma ngemuva kwaso, shayela udokotela wakho ngokushesha: ukopha okungavamile kwesitho sangasese sowesifazane; izikhathi ezingajwayelekile zokuya esikhathini; ushintsho ekukhishweni kwesitho sangasese sowesifazane, ikakhulukazi uma ukukhishwa kuba negazi, nsundu, noma ukugqwala; ubuhlungu noma ingcindezi ethangeni (indawo yesisu engezansi kwenkinobho yesisu); ukuvuvukala kwemilenze noma isisa; ubuhlungu besifuba; ukuphelelwa umoya; ukukhwehlela igazi; ubuthakathaka obungazelelwe, ukudikiza, noma ukuba ndikindiki ebusweni bakho, engalweni, noma emlenzeni, ikakhulukazi ohlangothini olulodwa lomzimba wakho; ukudideka okungazelelwe; ukukhuluma kanzima noma ukuqonda; ubunzima obungazelelwe ukubona kwelinye noma kuwo womabili amehlo; ukuhamba ngokungazelelwe; isiyezi; ukulahlekelwa ibhalansi noma ukuxhumanisa; noma ikhanda elibuhlungu ngokuzumayo.

Gcina wonke ama-aphoyintimenti nodokotela wakho. Uzodinga ukuba nokuhlolwa kwabesifazane (ukuhlolwa kwezitho zabesifazane) njalo ukuthola izimpawu zokuqala zomdlavuza wesibeletho.

Uma ucabanga ukuthatha i-tamoxifen ukunciphisa ithuba lokuthi uzoba nomdlavuza webele, kufanele ukhulume nodokotela wakho ngezingozi nezinzuzo zalokhu kwelashwa. Wena nodokotela wakho nizonquma ukuthi inzuzo engaba khona yokwelashwa kwe-tamoxifen izifanele yini izingozi zokuphuza umuthi. Uma udinga ukuthatha i-tamoxifen ukwelapha umdlavuza webele, izinzuzo ze-tamoxifen zidlula izingozi.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa nge-tamoxifen futhi isikhathi ngasinye lapho ugcwalisa umuthi wakho. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) noma iwebhusayithi yomkhiqizi ukuthola i-Medication Guide.

I-Tamoxifen isetshenziselwa ukwelapha umdlavuza webele osudlulele kwezinye izitho zomzimba kwabesilisa nabesifazane. Isetshenziselwa ukwelapha umdlavuza webele wokuqala kwabesifazane asebevele belashwa ngokuhlinzwa, ngemisebe, kanye / noma ngamakhemikhali. Isetshenziselwa ukunciphisa ubungozi bokuthola uhlobo olubi kakhulu lomdlavuza webele kwabesifazane abake baba ne-ductal carcinoma in situ (DCIS; uhlobo lomdlavuza webele ongasakazeki ngaphandle komsele wobisi lapho wakheka khona) nalabo asebeke baba welashwa ngokuhlinzwa nangemisebe. Isetshenziselwa ukunciphisa ingozi yomdlavuza webele kwabesifazane abasengozini enkulu yokuthola lesi sifo ngenxa yeminyaka yabo, umlando wezempilo wabo, kanye nomlando wezokwelapha womndeni.

I-Tamoxifen isekilasini lemithi eyaziwa ngokuthi ama-antiestrogens. Ivimba ukusebenza kwe-estrogen (i-hormone yabesifazane) esifubeni. Lokhu kungamisa ukukhula kwezinye izicubu zesifuba ezidinga i-estrogen ukuze zikhule.

I-Tamoxifen iza njengethebhulethi ezothathwa ngomlomo. I-Tamoxifen ivame ukuthathwa kanye noma kabili ngosuku noma ngaphandle kokudla. Thatha i-tamoxifen cishe ngesikhathi esifanayo (ama) nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze noma yini ongayiqondi. Thatha i-tamoxifen njengoba nje iqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Gwinya amaphilisi e-tamoxifen ephelele; ungawahlukanisi, ungawahlafune noma uwagxoze. Gwinya amaphilisi ngamanzi noma nganoma yisiphi esinye isiphuzo esingenalo utshwala.

Uma uthatha i-tamoxifen ukuvimbela umdlavuza webele, cishe uzoyithatha iminyaka emihlanu. Uma uthatha i-tamoxifen ukwelapha umdlavuza webele, udokotela wakho uzonquma ukuthi ukwelashwa kwakho kuzohlala isikhathi esingakanani. Ungayeki ukuthatha i-tamoxifen ngaphandle kokukhuluma nodokotela wakho.

Uma ukhohlwa ukuthatha umthamo we-tamoxifen, thatha isilinganiso esilahlekile ngokushesha nje lapho usikhumbula, bese uthatha umthamo wakho olandelayo njengenjwayelo. Kodwa-ke, uma sekuyisikhathi sedosi yakho elandelayo, weqa umthamo ophuthelwe bese uqhubeka nesimiso sakho sokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Tamoxifen nayo iyasetshenziswa kwesinye isikhathi ukukhuthaza ukukhiqizwa kweqanda (ukukhiqizwa kwamaqanda) kwabesifazane abangavezi amaqanda kodwa bafise ukukhulelwa. I-Tamoxifen kwesinye isikhathi isetshenziselwa ukwelapha iMcCune-Albright syndrome (MAS; isimo esingahle sidale izifo zamathambo, ukukhula kokuqala kwezocansi, namabala amnyama esikhunjeni ezinganeni). Khuluma nodokotela wakho ngezingozi ezingenzeka zokusebenzisa lesi sidakamizwa ngesimo sakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-tamoxifen,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-tamoxifen noma eminye imithi.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma ikuphi kokulandelayo: aminoglutethimide (Cytadren); i-anastrozole (Arimidex), i-bromocriptine (iParlodel); imishanguzo yokwelashwa ngamakhemikhali njenge-cyclophosphamide (Cytoxan, Neosar) letrozole (Femara); i-medroxyprogesterone (iDepo-Provera, iProvera, ePrempro); i-phenobarbital; kanye ne-rifampin (i-Rifadin, i-Rimactane). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• ngaphezu kwezimo ezibalwe esigabeni SESEXWAYISO ESIBALULEKILE, tshela udokotela wakho uma ngabe uke waba namazinga aphezulu egazi we-cholesterol.
• utshele udokotela wakho uma ukhulelwe noma uhlela ukukhulelwa. Akufanele uhlele ukukhulelwa ngenkathi uthatha i-tamoxifen noma izinyanga ezimbili ngemuva kokwelashwa kwakho. Udokotela wakho angenza isivivinyo sokukhulelwa noma akutshele ukuthi uqale ukwelashwa kwakho ngesikhathi sokuya esikhathini ukuze uqiniseke ukuthi awukhulelwe lapho uqala ukuthatha i-tamoxifen. Uzodinga ukusebenzisa indlela ethembekile yokulawula ukubeletha engeyona eye-hormone ukuvimbela ukukhulelwa ngenkathi uthatha i-tamoxifen nezinyanga ezi-2 ngemuva kokwelashwa kwakho. Khuluma nodokotela wakho ngezinhlobo zokulawulwa kokubeletha ezikulungele, bese uqhubeka nokulawula ukubeletha noma ngabe ungayi esikhathini esijwayelekile ngesikhathi sokwelashwa kwakho. Yeka ukuthatha i-tamoxifen bese ushayela udokotela wakho ngokushesha uma ucabanga ukuthi ukhulelwe ngesikhathi sokwelashwa kwakho. I-Tamoxifen ingalimaza umbungu.
• tshela udokotela wakho uma uncelisa. Akufanele uncelise ibele ngesikhathi sokwelashwa kwakho nge-tamoxifen.
• Tshela bonke odokotela bakho nabanye abahlinzeki bezempilo ukuthi uthatha i-tamoxifen.
• kusazodingeka ukuthi ubheke izimpawu zokuqala zomdlavuza webele ngoba kungenzeka ukuthuthukisa umdlavuza webele noma ngabe ukwelashwa nge-tamoxifen. Khuluma nodokotela wakho mayelana nokuthi kufanele uzihlole kaningi kangakanani amabele akho, udokotela akuhlole amabele, futhi ube nama-mammograms (ukuhlolwa kwe-x-ray kwamabele). Shayela udokotela wakho ngokushesha uma uthola isigaxa esisha esifubeni sakho.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Tamoxifen ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ukwanda kwamathambo noma isimila
• ubuhlungu noma ubomvu eduze nendawo yesimila
• ukushisa okushisayo
• isicanucanu
• ukukhathala ngokweqile
• isiyezi
• ukudana
• ikhanda
• ukuncipha kwezinwele
• ukuncipha komzimba
• amajaqamba esiswini
• ukuqunjelwa
• ukulahlekelwa isifiso sobulili noma ikhono (emadodeni)

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalezi zimpawu ezilandelayo noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:

• izinkinga zokubona
• ukulahlekelwa isifiso sokudla
• ukuphuzi kwesikhumba noma kwamehlo
• ukulimaza noma ukopha okungavamile
• imfiva
• amabhamuza
• ukuqubuka
• ukuvuvukala kwamehlo, ubuso, izindebe, ulimi, umphimbo, izandla, izingalo, izinyawo, amaqakala noma imilenze engezansi
• ukoma
• ubuthakathaka bemisipha
• ukungahlaliseki

I-Tamoxifen ingakhuphula ubungozi bokuthi uzoba neminye imidlavuza, kubandakanya umdlavuza wesibindi. Khuluma nodokotela wakho ngale ngozi.

I-Tamoxifen ingakhuphula ubungozi bokuthi uzoba ne-cataract (ukufiphalisa ilensi esweni) engadinga ukwelashwa ngokuhlinzwa. Khuluma nodokotela wakho ngale ngozi.

I-Tamoxifen ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Gcina i-tamoxifen esitsheni efike kuso, ivaliwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka:

• ukuzamazama okungalawuleki kwengxenye yomzimba
• ukungazinzi
• isiyezi

• Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ku-tamoxifen.
• Ngaphambi kokwenza noma yiluphi uvivinyo lwe-laboratory, tshela udokotela wakho kanye nabasebenzi be-laboratory ukuthi uthatha i-tamoxifen.
• Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Khuluma nosokhemisi wakho uma unemibuzo mayelana nokugcwalisa imishanguzo yakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Nolvadex^®
• I-Soltamox^®¶

^¶ Lo mkhiqizo onophawu alusekho emakethe. Ezinye izindlela ezijwayelekile zingatholakala.