I-Sargramostim

-Delile

• Ngaphambi kokusebenzisa umjovo we-sargramostim,
• I-Sargramostim ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

I-Sargramostin isetshenziselwa ukunciphisa amathuba okutheleleka kubantu abane-leukemia enamandla (i-AML; uhlobo lomdlavuza wamaseli amhlophe egazi) futhi bathola imishanguzo ye-chemotherapy enganciphisa inani lama-neutrophils (uhlobo lweseli legazi elidingekayo ukulwa ukutheleleka). I-Sargramostin isetshenziswa futhi kubantu abasebenza ukufakelwa amangqamuzana egazi, kubantu abafakelwa umnkantsha wethambo, nokulungisa igazi leukapheresis (ukwelashwa lapho amaseli athile egazi akhishwa khona emzimbeni abese ebuyiselwa emzimbeni olandelayo amakhemikhali). I-Sargramostim isetshenziswa futhi kubantu abangaphendulanga ngemuva kokuthola ukufakelwa umnkantsha wegazi. ISargramostin isekilasini lemithi ebizwa ngezinto ezikhuthaza amakoloni. Isebenza ngokusiza umzimba ukuthi wenze ama-neutrophil amaningi namanye amaseli egazi.

ISargramostim iza njengesisombululo (uketshezi) noma impuphu exutshwe noketshezi ukujova ngomgogodla (ngaphansi kwesikhumba) noma ngemithambo (emthanjeni). Ifakwa (ijojowe kancane) esikhathini samahora ama-2 kuye kwangama-24 kanye ngosuku. Kungabuye kufakwe ngaphansi kwesikhumba kanye nsuku zonke. Ubude bokwelashwa kwakho buya ngesimo onaso nokuthi umzimba wakho uphendula kahle kanjani emithini.

Uma usebenzisa i-sargramostim ukunciphisa ubungozi bokutheleleka ngesikhathi se-chemotherapy, uzothola umuthi okungenani izinsuku ezine ngemuva kokuthola umthamo wakho wokugcina womjikelezo ngamunye we-chemotherapy. Uzoqhubeka nokuthola umuthi nsuku zonke kuze kubalwe amaseli egazi lakho abuyele kokujwayelekile noma kuze kube amasonto ayisithupha. Uma usebenzisa i-sargramostim ukulungiselela igazi lakho leukapheresis, uzothola umuthi kanye nsuku zonke kuze kufike i-leukapheresis yokugcina. Uma usebenzisa i-sargramostim ngoba uthola ukufakelwa amangqamuzana egazi, uzothola umuthi oqala ngosuku lokufakelwa kwamangqamuzana egazi bese uqhubeka okungenani izinsuku ezintathu. Uma usebenzisa i-sargramostim ukunciphisa ubungozi bokutheleleka ngesikhathi sokufakelwa komnkantsha wethambo, uzothola umuthi okungenani amahora angama-24 ngemuva kokuthola i-chemotherapy futhi futhi ngemuva kwamahora amabili kuya kwayi-4 ngemuva kokufakwa komnkantsha. Uma usebenzisa i-sargramostim ngoba awuphenduli ekufakweni komnkantsha wethambo, uzothola umuthi kanye ngosuku izinsuku eziyi-14. Ungayeki ukusebenzisa i-sargramostim ngaphandle kokukhuluma nodokotela wakho.

I-Sargramostim ingakunika umhlengikazi noma omunye umhlinzeki wezokunakekelwa kwempilo, noma ungatshelwa ukuthi ujove umuthi ekhaya. Uma uzofaka i-sargramostim, jove umuthi cishe ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Sebenzisa i-sargramostim njengoba nje kuqondisiwe. Ungayisebenzisi ngaphezulu noma ngaphansi kwayo noma uyisebenzise kaningi kunokuyalelwa ngudokotela wakho.

Uma uzobe ujova i-sargramostim ngokwakho, umhlinzeki wezokunakekelwa kwezempilo uzokukhombisa ukuthi ungawujova kanjani umuthi. Qiniseka ukuthi uyaziqonda lezi zinkomba. Buza umhlinzeki wakho wezokunakekelwa kwezempilo uma unemibuzo mayelana nokuthi kufanele ujove kuphi i-sargramostim, ukuthi ungawunikeza kanjani umjovo, hlobo luni lomjovo ozolusebenzisa, noma ukuthi ungazilahla kanjani izinaliti nemijovo esetshenzisiwe ngemuva kokufaka umuthi.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

I-Sargramostim kwesinye isikhathi isetshenziselwa ukwelapha izinhlobo ezithile ze-myelodysplastic syndrome (iqembu lezimo lapho umnkantsha ukhiqiza amangqamuzana egazi angafakwanga kahle futhi angavezi amaseli egazi anempilo anele) kanye ne-aplastic anemia (isimo lapho umnkantsha ungatholi khona akhiqize amaseli egazi amasha anele). I-Sargramostim kwesinye isikhathi isetshenziselwa ukunciphisa amathuba okutheleleka kubantu abanegciwane lesandulela ngculazi (i-HIV). Khuluma nodokotela wakho ngezingozi zokusebenzisa lo muthi ngesimo sakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokusebenzisa umjovo we-sargramostim,

• Tshela udokotela wakho kanye nosokhemisi uma une-allergies ku-sargramostim, imvubelo, noma imuphi omunye umuthi, noma yiziphi izithako zomjovo we-sargramostim. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho i-betamethasone (iCelestone), i-dexamethasone (i-Decadron), i-lithium (i-Lithobid), i-methylprednisolone (i-Medrol) ne-prednisone.Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• utshele udokotela wakho ukuthi uyelashwa yini noma wake welashwa ngemisebe noma uma uke waba nomdlavuza, i-edema (ukuvuvukala kwesisu, izinyawo, amaqakala, noma imilenze engezansi), noma yiluphi uhlobo lwesifo senhliziyo, ukwehluleka kwenhliziyo , ukushaya kwenhliziyo okungajwayelekile, amaphaphu, izinso, noma isifo sesibindi.
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi usebenzisa i-sargramostim, shayela udokotela wakho.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi usebenzisa i-sargramostim.
• kufanele wazi ukuthi i-sargramostim inciphisa ubungozi bokutheleleka, kepha ayivimbeli konke ukutheleleka okungakhula ngesikhathi noma ngemuva kwe-chemotherapy. Shayela udokotela wakho ngokushesha uma uba nezimpawu zokutheleleka ezifana nomkhuhlane, ukubanda, umphimbo obuhlungu, noma ukukhwehlela okuqhubekayo nokuminyana.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

I-Sargramostim ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ububomvu, ukuvuvukala, ukulinyazwa, ukulunywa noma isigaxa endaweni lapho umjovo wafakwa khona
• ubuhlungu bamathambo, obuhlangene, noma besisipha
• ikhanda
• isicanucanu
• ukuhlanza
• isifo sohudo
• ubuhlungu besisu
• izilonda zomlomo
• ukulahlekelwa isifiso sokudla
• ukulahleka kwezinwele

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukuphefumula okuncane noma ukuphefumula okusheshayo
• ukuphefumula kanzima
• isifuba
• isiyezi
• ukujuluka
• isifuba
• ukuqubuka
• ukulunywa
• ukuvuvukala kuzungeze umlomo, ubuso, amehlo, isisu, izinyawo, amaqakala noma imilenze engezansi
• ukuzuza kwesisindo ngokungazelelwe
• ubuhlungu besifuba
• ukushaya kwenhliziyo okusheshayo noma okungajwayelekile
• ukuquleka
• ukulinyazwa okungajwayelekile noma ukumakwa okunsomi ngaphansi kwesikhumba
• ukopha okungavamile
• ukuphuma kwamakhala
• ukukhathala okungajwayelekile noma ubuthakathaka
• ukuncipha kokuchama

I-Sargramostim ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, kude nelanga, ivaliwe, futhi lapho izingane zingafinyeleleki khona. Gcina i-sargramostim esiqandisini. Ungafaki iqhwa noma unyakazise i-sargramostim. Izitsha ezivuliwe ze-sargramostim zingafakwa esiqandisini izinsuku ezifika kwezingu-20. Lahla izitsha ezivuliwe ngemuva kwezinsuku ezingama-20.

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• ukuphelelwa umoya
• ukukhathala okungajwayelekile noma ubuthakathaka
• imfiva
• ukushaya kwenhliziyo okusheshayo noma okungajwayelekile
• isicanucanu
• ikhanda
• ukuqubuka

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ku-sargramostim.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-leukine^®

• Isici Esikhuthaza I-Granulocyte-Macrophage Colony
• GM-CSF