Inaliti ye-Amifostine

-Delile

• Ngaphambi kokuthola i-amifostine,
• I-Amifostine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

I-Amifostine isetshenziswa ukuvikela izinso emiphumeleni eyingozi ye-chemotherapy drug cisplatin ezigulini ezithola lo muthi wokwelapha umdlavuza we-ovari. I-Amifostine nayo isetshenziselwa ukunciphisa ukoma emlonyeni okubangelwa ukwelashwa ngemisebe ngemuva kokuhlinzwa komdlavuza wekhanda nowentamo. I-Amifostine isekilasini lemithi ebizwa ngama-cytoprotectants. Isebenza ngokuvikela imiphumela emibi yemithi yokwelashwa ngamakhemikhali kanye nokwelashwa ngemisebe.

I-Amifostine iza njengempuphu ezohlanganiswa noketshezi oluzofakwa ngaphakathi (emthanjeni) ngudokotela noma umhlengikazi esikhungweni sezokwelapha. Lapho i-amifostine isetshenziselwa ukuvikela izinso emiphumeleni emibi ye-cisplatin, imvamisa inikezwa ngaphezu kwemizuzu engu-15 kuqala imizuzu engama-30 ngaphambi kokuthola ukwelashwa ngamakhemikhali. Lapho i-amifostine isetshenziselwa ukunciphisa umlomo owomile omubi obangelwa ukwelashwa ngemisebe, imvamisa inikezwa ngaphezu kwemizuzu emi-3 kuqala imizuzu eyi-15-30 ngaphambi kokwelashwa ngemisebe.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

I-Amifostine kwesinye isikhathi isetshenziselwa ukuvimbela nokunciphisa imiphumela emibi ehambisana nemithi ethile yokwelashwa ngamakhemikhali noma ukwelashwa ngemisebe kanye nasekwelapheni izinhlobo ezithile zezifo zamangqamuzana egazi.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola i-amifostine,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-amifostine, noma imiphi eminye imithi, noma yiziphi izithako zomjovo we-amifostine. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukukhuluma ngemithi yomfutho wegazi ophakeme. Udokotela wakho uzokutshela ukuthi yeka ukuphuza umuthi wegazi lakho emahoreni angama-24 ngaphambi kokuthola umjovo we-amifostine. Eminye imithi eminingi ingaxhumana ne-amifostine, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo.
• Tshela udokotela wakho uma uke waba nesifo senhliziyo, ukushaya kwenhliziyo okungafanele, ukwehluleka kwenhliziyo, noma isifo sohlangothi noma i-ministroke.
• utshele udokotela wakho uma ukhulelwe noma uhlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthola i-amifostine, shayela udokotela wakho. Akufanele uncelise ibele ngesikhathi sokwelashwa kwakho nge-amifostine.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

I-Amifostine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isicanucanu
• ukuhlanza
• ukuqhuma noma ukuzwa imfudumalo
• Ukugodola noma ukuzwa amakhaza
• umuzwa ojwayelekile wokukhathala
• imfiva
• ukozela
• ukuthimula
• izinqa

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

• ukuphelelwa umoya
• isiyezi
• ukungaboni kahle
• ukuquleka
• isithuthwane
• ukuqina kwesifuba
• ubuhlungu besifuba
• ukuqubuka
• isifuba
• ukulunywa
• ukuphefumula kanzima noma ukugwinya
• isikhumba esihlabayo noma esishayayo
• ukushaya kwenhliziyo okusheshayo, okuhamba kancane, noma okushaya ngamandla

I-Amifostine ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• isiyezi
• ubumhlophe
• ukuquleka

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ku-amifostine.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

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