I-Indinavir

-Delile

• Ngaphambi kokuthatha indinavir,
• I-Indinavir ingadala imiphumela emibi. Tshela udokotela wakho uma lesi sibonakaliso sinzima noma singapheli:
• I-Indinavir ingadala imiphumela emibi. Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

I-Indinavir isetshenziswa kanye neminye imithi yokwelapha ukutheleleka nge-immunodeficiency virus (HIV). I-Indinavir isekilasini lemithi ebizwa nge-protease inhibitors. Isebenza ngokunciphisa inani le-HIV egazini. Yize i-indinavir ingayelaphi i-HIV, ingahle inciphise amathuba okuba ne-immunodeficiency syndrome (i-AIDS) kanye nezifo ezihlobene ne-HIV ezinjengezifo ezibucayi noma umdlavuza. Ukuthatha le mithi kanye nokwenza ucansi oluphephile nokwenza ezinye izinguquko kwimpilo yakho kunganciphisa ingozi yokudlulisela igciwane lesandulela ngculaza kwabanye abantu.

I-Indinavir iza njengephilisi elizothathwa ngomlomo. Kuvame ukuthathwa njalo emahoreni ayisishiyagalombili (kathathu ngosuku). Thatha i-indinavir ngezikhathi ezifanayo nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-indinavir njengoba nje kuqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Thatha i-indinavir esiswini esingenalutho, ihora eli-1 ngaphambi kokudla noma amahora amabili ngemuva kokudla, ngamanzi, ubisi olushelelayo noma olungenawo amafutha, ujusi, ikhofi noma itiye. Kodwa-ke, uma i-indinavir ikucasula isisu sakho, ingathathwa ngokudla okulula, okufana nethosi eyomile noma ama-cornflakes anobisi olushelelayo noma olungenawo amafutha. Khuluma nodokotela wakho noma usokhemisi mayelana nokuthi yikuphi ukudla okungathathwa nge-indinavir.

Ungayichobozi noma uyihlafune i-capsule, kepha ingavulwa futhi ixutshwe ne-puree yezithelo (efana nebhanana).

Qhubeka nokuphuza indinavir noma ngabe uzizwa uphilile. Ungayeki ukuthatha indinavir ngaphandle kokukhuluma nodokotela wakho.

Udokotela wakho angadinga ukuphazamisa ukwelashwa kwakho uma uhlangabezana nemiphumela ethile emibi. Qiniseka ukuthi utshela udokotela wakho ukuthi uzizwa kanjani ngenkathi welashwa nge-indinavir.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

I-Indinavir nayo iyasetshenziswa kwesinye isikhathi ngokuhlanganiswa neminye imithi yokwelapha abasebenzi bezokunakekelwa kwempilo kanye nabanye abantu abachayeke ekuthelelekeni nge-HIV ngemuva kokuhlangana ngengozi negazi, izicubu, noma olunye uketshezi lomzimba olonakele. Khuluma nodokotela wakho ngezingozi ezingenzeka zokusebenzisa lesi sidakamizwa ngesimo sakho.

Ngaphambi kokuthatha indinavir,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-indinavir, noma imiphi eminye imithi, noma iziphi izithako ezikuma-capsule e-indinavir. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• utshele udokotela wakho uma uthatha noma iyiphi yale mithi elandelayo: i-alfuzosin (i-Uroxatral); i-alprazolam (Xanax); i-amiodarone (i-Nexterone, i-Pacerone); i-cisapride (Propulsid) (ayitholakali e-U.S.); imishanguzo yohlobo lwe-ergot efana ne-dihydroergotamine (i-DHE 45, i-Migranal), i-ergonovine (i-Ergotrate), i-ergotamine (i-Ergomar, i-Cafergot, i-Migergot), ne-methylergonovine (i-Methergine); i-lovastatin (Altoprev, Mevacor); i-lurasidone (Latuda); i-midazolam (ihunyushiwe) ngomlomo; ipimozide (i-Orap); i-sildenafil (uphawu lwe-Revatio kuphela olusetshenziselwa isifo samaphaphu); simvastatin (iZocor, eVytorin); noma i-triazolam (Halcion). Udokotela wakho mhlawumbe uzokutshela ukuthi ungathathi i-indinavir.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, kanye nezithako zokudla okunomsoco ozithathayo noma ohlela ukuzithatha. Qiniseka ukuthi usho noma ikuphi kokulandelayo: bosentan (Tracleer); ama-calcium-channel blocker anjenge-amlodipine (Norvasc, e-Amturnide, eTekamlo), i-felodipine, i-nicardipine, ne-nifedipine (i-Adalat, i-Afeditab, i-Procardia); carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, abanye); imithi yokwehlisa i-cholesterol (ama-statins) afana ne-atorvastatin (Lipitor, eCaduet) ne-rosuvastatin (Crestor); i-clarithromycin (i-Biaxin, ku-PrevPac); i-colchicine (Colcrys, Mitigare, ku-Col-Probenecid); i-dexamethasone; i-fluconazole (iDiflucan); i-fluticasone (Flonase, Flovent, e-Advair, eDymista); itraconazole (Onmel, Sporanox); ketoconazole (Extina, Nizoral, Xolegel); eminye imithi ye-HIV kubandakanya i-atazanavir (Reyataz, e-Evotaz), i-delavirdine (Rescriptor), i-efavirenz (i-Sustiva, e-Atripla), i-nelfinavir (i-Viracept), i-nevirapine (i-Viramune), i-ritonavir (i-Norvir, e-Kaletra, e-Viekira Pak), ne-saquinavir (I-Invirase); imishanguzo yokushaya kwenhliziyo okungajwayelekile njenge-lidocaine (Glydo, Xylocaine) ne-quinidine (eNuedexta); imithi evimbela amasosha omzimba njenge-cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune), ne-tacrolimus (Astagraf XL, Envarsus XR, Prograf); i-midazolam (ihunyushiwe) ngomjovo; ama-phosphodiesterase inhibitors (PDE-5 inhibitors) asetshenziselwa ukungasebenzi kahle kwe-erectile njenge-sildenafil (Viagra), i-tadalafil (i-Adcirca, i-Cialis), ne-vardenafil (i-Levitra, e-Staxyn); i-phenobarbital; i-phenytoin (iDilantin, Phenytek); i-quetiapine (iSeroquel); i-rifabutin (i-Mycobutin); i-rifampin (iRifadin, iRimactane, eRifamate, eRifater); i-salmeterol (iSerevent, e-Advair); i-trazodone; kanye ne-venlafaxine (i-Effexor). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo eminingi ingaxhumana ne-indinavir, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu.
• utshele udokotela wakho ukuthi uthatha miphi imikhiqizo yamakhambi, ikakhulukazi iSt John's wort.
• uma uthatha i-didanosine (Videx), yithathe okungenani ihora elilodwa ngaphambi noma ngemuva kwe-indinavir.
• Tshela udokotela wakho uma uke waba ne-hemophilia (ukuphuma kwegazi lapho igazi lingajiyiki kahle), isifo sikashukela, noma isifo sezinso noma sesibindi.
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha i-indinavir, shayela udokotela wakho. Akufanele uncelise ibele uma utheleleke nge-HIV noma uma uphuza i-indinavir.
• kufanele wazi ukuthi amafutha omzimba wakho angakhuphuka noma ahambele ezindaweni ezahlukahlukene zomzimba wakho njengamabele akho, iqolo elingaphezulu, intamo, isifuba, nesisu. Ukulahleka kwamafutha emilenzeni, ezingalweni nasebusweni nakho kungenzeka.
• kufanele wazi ukuthi ungathola i-hyperglycemia (iyanda kushukela wakho wegazi) ngenkathi uthatha lo muthi, noma ngabe awunaso vele isifo sikashukela. Tshela udokotela wakho ngokushesha uma unanoma iyiphi yalezi zimpawu ezilandelayo ngenkathi uthatha i-indinavir: ukoma ngokweqile, ukuchama njalo, ukulamba ngokweqile, ukungaboni kahle, noma ubuthakathaka. Kubaluleke kakhulu ukubiza udokotela wakho ngokushesha uma unezinye zalezi zimpawu, ngoba ushukela wegazi ongelashwa ungadala isimo esibi esibizwa nge-ketoacidosis. I-Ketoacidosis ingasongela impilo uma ingelashwa kusenesikhathi. Izimpawu ze-ketoacidosis zifaka phakathi umlomo owomile, isicanucanu nokuhlanza, ukuphefumula okuncane, ukuphefumula okunuka izithelo, nokuncipha kokwazi.
• kufanele wazi ukuthi ngenkathi uthatha imishanguzo yokwelapha ukutheleleka nge-HIV, amasosha omzimba wakho angaqina futhi aqale ukulwa nezinye izifo ezazivele zisemzimbeni wakho. Lokhu kungadala ukuthi ube nezimpawu zalezo zifo. Uma unezimpawu ezintsha noma eziya ziba zimbi noma kunini ngesikhathi sokwelashwa kwakho nge-indinavir, qiniseka ukuthi utshela udokotela wakho.

Phuza okungenani ama-oun angu-1.5 (amalitha ayi-1.5), okuyizibuko ezingaba ngamasentimitha ayisithupha (240-milliliter), zamanzi noma ezinye iziphuzo njalo ngamahora angama-24.

Khuluma nodokotela wakho ngokudla isithelo samagilebhisi nokuphuza ijusi lamagilebhisi ngenkathi uthatha lo muthi.

Uma uphuthelwa umthamo ngaphansi kwamahora ama-2, thatha umthamo owulahlekile ngokushesha uma uwukhumbula. Kodwa-ke, uma uphuthelwa umthamo ngaphezu kwamahora ama-2, weqa umthamo ophuthelwe bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Indinavir ingadala imiphumela emibi. Tshela udokotela wakho uma lesi sibonakaliso sinzima noma singapheli:

• shintsha ngomqondo wokunambitha

I-Indinavir ingadala imiphumela emibi. Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukuqubuka
• isifuba
• ukulunywa
• isikhumba esihlabayo noma esishayayo
• ukuhlungu obusemhlane
• ubuhlungu ohlangothini lomzimba wakho
• maphakathi nobuhlungu besisu obuphansi
• igazi emchameni
• ubuhlungu bemisipha noma ubuthakathaka
• isicanucanu
• ukukhathala ngokweqile
• ukopha okungajwayelekile noma ukulinyazwa
• ukulahlekelwa isifiso sokudla
• ubuhlungu engxenyeni engenhla yangakwesokudla yesisu sakho
• izimpawu ezinjengomkhuhlane
• umchamo omnyama ophuzi noma onsundu
• ukuphuzi kwesikhumba noma kwamehlo
• ukuphelelwa umoya
• ukushaya kwenhliziyo okusheshayo
• ukudideka
• isiyezi
• ikhanda
• ukuphaphatheka

I-Indinavir ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. I-desiccant (i-agent yokumisa) ifakiwe nama-capsules akho; kugcine lokhu ebhodleleni lakho lomuthi ngaso sonke isikhathi. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• ubuhlungu ohlangothini lomzimba wakho
• igazi emchameni
• isicanucanu
• ukuhlanza
• isifo sohudo

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yakho ku-indinavir.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• UCrixivan^®

• IDV