I-Diclofenac neMisoprostol

-Delile

• Abesifazane abangakhulelwa ngokuvamile akufanele bathathe i-diclofenac ne-misoprostol. Kodwa-ke, wena nodokotela wakho ninganquma ukuthi inhlanganisela ye-diclofenac ne-misoprostol iyadingeka ukwelapha isimo sakho. Kuleso simo kufanele:
• Ngaphambi kokuthatha i-diclofenac ne-misoprostol,
• I-Diclofenac ne-misoprostol kungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalezi zimpawu ezilandelayo noma lezo ezishiwo esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha noma uthole usizo oluphuthumayo lwezokwelapha. Ungathathi enye i-diclofenac ne-misoprostol uze ukhulume nodokotela wakho.
• Izimpawu zokudlula ngokweqile zingafaka:

Ezigulini zesifazane:

Ungathathi i-diclofenac ne-misoprostol uma ukhulelwe noma uhlela ukukhulelwa. Uma ukhulelwa noma ucabanga ukuthi ungakhulelwa ngenkathi uthatha i-diclofenac ne-misoprostol, yeka ukuthatha imishanguzo bese ushayela udokotela wakho ngokushesha. I-Diclofenac ne-misoprostol kungadala ukukhulelwa kwesisu (ukulahleka kokukhulelwa), ukuphuma kwegazi okunzima, noma ukuzalwa ngaphambi kwesikhathi (ingane izalwa kusenesikhathi) uma ithathwa ngesikhathi sokukhulelwa.

Abesifazane abangakhulelwa ngokuvamile akufanele bathathe i-diclofenac ne-misoprostol. Kodwa-ke, wena nodokotela wakho ninganquma ukuthi inhlanganisela ye-diclofenac ne-misoprostol iyadingeka ukwelapha isimo sakho. Kuleso simo kufanele:

• vuma ukusebenzisa indlela ethembekile yokulawula ukubeletha ngenkathi welashwa futhi okungenani inyanga eyodwa noma umjikelezo owodwa wokuya esikhathini ngemuva kokwelashwa kwakho;
• uhlolwe igazi elingalungile ukukhulelwa kungasadluli amasonto ama-2 ngaphambi kokuqala ukuthatha i-diclofenac ne-misoprostol;
• qala ukuthatha imithi kuphela ngosuku lwesibili noma lwesithathu esikhathini esijwayelekile sokuya esikhathini.

Kuzo zonke iziguli:

Abantu abathatha izidakamizwa ezingezona ukuvuvukala (ama-NSAID) (ngaphandle kwe-aspirin) njenge-diclofenac kanye nenhlanganisela ye-misoprostol bangaba nengozi enkulu yokuhlaselwa yisifo senhliziyo noma isifo sohlangothi kunabantu abangayithathi le mithi. Le micimbi ingenzeka ngaphandle kwesixwayiso futhi ingadala ukufa. Le ngozi ingahle ibe phezulu kubantu abathatha ama-NSAID isikhathi eside. Ungayisebenzisi i-NSAID efana nenhlanganisela ye-diclofenac ne-misoprostol uma usanda kuhlaselwa yisifo senhliziyo, ngaphandle kwalapho uqondiswe ngudokotela wakho. Tshela udokotela wakho uma wena noma omunye emndenini wakho enesifo senhliziyo, ehlaselwa yisifo senhliziyo, noma sohlangothi, uma ubhema, nokuthi ngabe uke waba ne-cholesterol ephezulu, umfutho wegazi ophakeme noma isifo sikashukela. Thola usizo lwezokwelapha oluphuthumayo ngokushesha uma uhlangabezana nalezi zimpawu ezilandelayo: Ubuhlungu besifuba, ukuphefumula okuncane, ukuba buthakathaka engxenyeni eyodwa noma ohlangothini lomzimba, noma ukukhuluma okungaqinile.

Uma uzobe uhlolwa umthambo we-coronary bypass graft (CABG; uhlobo lokuhlinzwa kwenhliziyo), akufanele uthathe i-diclofenac ne-misoprostol ngaphambi noma ngemuva kokuhlinzwa.

Ama-NSAID afana ne-diclofenac angadala izilonda, ukuphuma kwegazi, noma izimbobo esiswini noma emathunjini. IMisoprostol ithathwa ihlanganiswe ne-diclofenac ukuvikela isisu namathumbu, kepha kungenzeka ingavimbeli wonke umonakalo kulezi zingxenye zomzimba. Izinkinga zesisu namathumbu zingakhula nganoma yisiphi isikhathi ngesikhathi sokwelashwa, zingenzeka ngaphandle kwezimpawu zokuxwayisa, futhi zingadala nokufa. Ingozi ingase ibe phezulu kubantu abathatha ama-NSAID isikhathi eside, sebekhulile ngeminyaka, benempilo ebuthaka, bebhema, noma bephuza utshwala obuningi ngenkathi bethatha i-diclofenac ne-misoprostol. Tshela udokotela wakho uma uthatha noma imuphi wale mithi elandelayo: ama-anticoagulants (’ama-thinner egazi’) afana ne-warfarin (Coumadin, Jantoven); i-aspirin; amanye ama-NSAID afana ne-ibuprofen (Advil, Motrin) ne-naproxen (Aleve, Naprosyn); i-steroids yomlomo efana ne-dexamethasone, i-methylprednisolone (i-Medrol), ne-prednisone (i-Rayos); i-serotonin reuptake inhibitors (SSRIs) ekhethiwe njenge-citalopram (Celexa), i-fluoxetine (i-Prozac, i-Sarafem, i-Selfemra, ku-Symbyax), i-fluvoxamine (i-Luvox), i-paroxetine (i-Brisdelle, i-Paxil, i-Pexeva) ne-sertraline (i-Zoloft); noma i-serotonin norepinephrine reuptake inhibitors (SNRIs) efana ne-desvenlafaxine (Khedezla, Pristiq), duloxetine (Cymbalta), ne-venlafaxine (Effexor XR). Tshela udokotela wakho uma uphuma noma yini esiswini noma emathunjini noma uma unezinye zalezi zimpawu: ukuhlanza into enegazi noma ebukeka njengezizathu zekhofi, igazi esitulweni, noma izitulo ezimnyama nezokulinda. ngaphambi kokuba uqale ukwelashwa kwakho nge-diclofenac ne-misoprostol. Udokotela wakho mhlawumbe uzokutshela ukuthi ungathathi i-diclofenac ne-misoprostol. Phinda utshele udokotela wakho uma uke waba nezilonda noma unenkinga yokopha. Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo, yeka ukuthatha i-diclofenac ne-misoprostol bese ufonela udokotela wakho: ubuhlungu besisu, isilungulela, ukuhlanza into enegazi noma ebukeka njengezizathu zekhofi, igazi esitokisini, noma indle emnyama neyokulinda.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzoqapha izimpawu zakho ngokucophelela futhi mhlawumbe uzo-oda izivivinyo ezithile ukuze ahlole impendulo yomzimba wakho ku-diclofenac ne-misoprostol. Qiniseka ukuthi utshela udokotela wakho ukuthi uzizwa kanjani ukuze udokotela wakho akwazi ukukubeka inani elifanele lemithi yokwelapha isimo sakho ngengozi ephansi kakhulu yemiphumela emibi kakhulu.

Unganiki lo muthi komunye umuntu, ikakhulukazi owesifazane okhulelwe noma ongakhulelwa.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi le-diclofenac ne-misoprostol kanye noMhlahlandlela Wezokwelapha ojwayelekile wama-NSAID lapho uqala ukwelashwa kwakho futhi njalo lapho ugcwalisa umuthi wakho. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) noma iwebhusayithi yomkhiqizi ukuthola iphepha lolwazi lesiguli kanye noMhlahlandlela Wezokwelapha.

Inhlanganisela ye-diclofenac ne-misoprostol isetshenziselwa ukudambisa izinhlungu, isizotha, ukuvuvukala nokuqina okubangelwa i-osteoarthritis (i-arthritis ebangelwa ukuwohloka kolwelwesi lwamajoyini) kanye nesifo samathambo (isifo samathambo esibangelwa ukuvuvukala kolwelwesi lwamajoyini) ezigulini ezisengozini enkulu yokuba nezilonda esiswini. I-Diclofenac isekilasini lemithi ebizwa ngama-NSAID. Isebenza ngokumisa ukukhiqizwa komzimba wento ebangela ubuhlungu nokuvuvukala. IMisoprostol isekilasini lemithi ebizwa nge-prostaglandins. Kuvimbela izilonda ezibangelwa i-diclofenac ngokuvikela ulwelwesi lwesisu nokunciphisa ukukhiqizwa kwe-asidi esiswini.

Inhlanganisela ye-diclofenac ne-misoprostol iza njengethebhulethi ezothathwa ngomlomo. Imvamisa kuthathwa ngokudla kabili noma kane ngosuku. Ukukusiza ukuthi ukhumbule ukuthatha i-diclofenac ne-misoprostol, yithathe ngezikhathi ezifanayo nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha inhlanganisela ye-diclofenac ne-misoprostol njengoba iqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Gwinya wonke amaphilisi; ungawahlukanisi, ungawahlafune noma uwagxoze. Ungaphuzi amaphilisi aphukile noma alimele.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-diclofenac ne-misoprostol,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-diclofenac (Cambia, Flector, Pennsaid, Solaraze, Voltaren XR, Zipsor, Zorvolex), misoprostol (Cytotec), aspirin noma amanye ama-NSAID afana ne-ibuprofen (Advil, Motrin) kanye ne-naproxen (Aleve, UNaprosyn); ama-prostaglandin afana ne-alprostadil (Caverject, Edex, Muse), carboprost (Hemabate), dinoprostone (Cervidil, Prepidil, Prostin E2) kanye ne-mifepristone (Korlym, Mifeprex); noma imuphi omunye umuthi, noma iziphi izithako ezingasebenzi kumaphilisi e-diclofenac nakuma-misoprostol. Buza usokhemisi wakho ukuthola uhlu lwezithako ezingasebenzi.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yimiphi imithi ebhalwe esigabeni ESIBALULEKILE SEXWAYISO nanoma yikuphi okulandelayo: i-angiotensin-converting enzyme (ACE) inhibitors efana ne-benazepril (Lotensin, eLotrel), i-captopril, i-enalapril (i-Vasotec, e-Vaseretic), i-fosinopril lisinopril (ngesiZestoretic), moexipril (Univasc, in Uniretic), perindopril (Aceon, in Prestalia), quinapril (Accupril, in Quinaretic), ramipril (Altace), kanye netrandolapril (Mavik, eTarka); ama-angiotensin receptor blockers anjenge-candesartan (Atacand, e-Atacand HCT), eprosartan (Teveten), irbesartan (Avapro, e-Avalide), losartan (Cozaar, e-Hyzaar), olmesartan (Benicar, e-Azor, e-Benicar HCT, e-Tribenzor), i-telmisartan (Micardis, e-Micardis HCT, e-Twynsta), ne-valsartan (e-Exforge HCT); ama-antibiotic; ama-beta blocker anjenge-atenolol (Tenormin, in Tenoretic), labetalol (Trandate), metoprolol (Lopressor, Toprol XL, eDutoprol), nadolol (Corgard, eCorzide), kanye nepropranolol (Hemangeol, Inderal, Innopran); i-cyclosporine (Geograf, Neoral, Sandimmune); i-digoxin (i-Lanoxin); isisu (‘amaphilisi amanzi’); i-insulin nemithi yomlomo yesifo sikashukela; imithi yokuquleka; i-methotrexate (i-Otrexup, i-Rasuvo, i-Trexall); i-lithium (i-Lithobid); i-phenobarbital; i-rifampin (Rifadin, Rimacatane, eRifamate, eRifater); tacrolimus (Astagraf, Envarsus XR, Prograf); kanye ne-voriconazole (Vfend). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo ingaxhumana ne-diclofenac ne-misoprostol, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu.
• khuluma nodokotela wakho uma udinga ukuthatha i-antacid ngesikhathi sokwelashwa kwakho nge-diclofenac ne-misoprostol. Akufanele uthathe ama-antacids aqukethe i-magnesium (Mylanta, abanye). Udokotela wakho angakutshela ukuthi ungathatha i-antacid equkethe i-aluminium noma i-calcium.
• Tshela udokotela wakho uma ngabe uke waba nanoma yimiphi imibandela eshiwo esigabeni ESIBALULEKILE SESEXWAYISO noma isifo sokuvuvukala kwamathumbu (ukuvuvukala kolwelwesi lwamathumbu okungadala uhudo olubuhlungu noma olunegazi nokucinana); isifuba somoya, ikakhulukazi uma unamakhala agxishiwe kaningi noma agijimayo noma ama-polyp acinene (ukuvuvukala kocingo lwekhala); i-lupus (isimo lapho umzimba uhlasela khona izicubu nezitho zawo eziningi, imvamisa kufaka isikhumba, amalunga, igazi nezinso); i-hepatic porphyria (ukwanda okungavamile kwenani lezinto ezithile zemvelo ezenziwe yisibindi); ukwehluleka kwenhliziyo; isifo sesibindi noma sezinso; noma ukuvuvukala kwezandla, izinyawo, amaqakala, noma imilenze engezansi.
• tshela udokotela wakho uma uncelisa.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi uthatha i-diclofenac ne-misoprostol.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Diclofenac ne-misoprostol kungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isifo sohudo
• igesi noma ukuqunjelwa
• ukuqunjelwa

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalezi zimpawu ezilandelayo noma lezo ezishiwo esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha noma uthole usizo oluphuthumayo lwezokwelapha. Ungathathi enye i-diclofenac ne-misoprostol uze ukhulume nodokotela wakho.

• ukuzuza kwesisindo okungaqondakali
• ukuphefumula okuncane noma ukuphefumula kanzima
• ukuvuvukala esiswini, emaqakaleni, ezinyaweni, noma emilenzeni
• ukukhathala ngokweqile
• ukungabi namandla
• ukulunywa
• isisu esibuhlungu
• ukulahlekelwa isifiso sokudla
• ubuhlungu engxenyeni engenhla kwesokudla yesisu
• ukuphuzi kwesikhumba noma kwamehlo
• izimpawu ezinjengomkhuhlane
• isikhumba esiphaphathekile
• ukushaya kwenhliziyo okusheshayo
• ikhanda
• intamo elukhuni
• Umphimbo obuhlungu
• ubuhlungu bemisipha
• ukudideka
• ukuzwela ekukhanyeni
• imfiva
• amabhamuza
• ukuqubuka
• isifuba
• ukuvuvukala kwamehlo, ubuso, izindebe, ulimi, umphimbo, izingalo, noma izandla
• ubunzima bokugwinya
• ukushaqeka
• ukopha okungavamile kwesitho sangasese sowesifazane
• kunamafu, umbala ogqamile, noma umchamo onegazi
• ukuhlungu obusemhlane
• ukuchama okunzima noma okubuhlungu

I-Diclofenac ne-misoprostol kungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka:

• ubuhlungu besisu
• ukuhlanza
• isifo sohudo
• ukudideka
• ukozela
• ithoni yemisipha ephansi
• ukuzamazama okungalawuleki kwengxenye yomzimba
• isithuthwane
• ukuphelelwa umoya
• imfiva
• ukushesha, ukushaya ngamandla, noma ukushaya kwenhliziyo okuhamba kancane
• isiyezi
• ukuquleka

Ngaphambi kokwenza noma yiluphi uvivinyo lwelabhoratri, tshela udokotela wakho kanye nabasebenzi belebhuthi ukuthi uthatha i-diclofenac ne-misoprostol.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho.Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Arthrotec^® (equkethe iDiclofenac, iMisoprostol)