ICapecitabine

-Delile

• Ngaphambi kokuthatha i-capecitabine,
• ICapecitabine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi.Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka:

ICapecitabine ingadala ukopha okungathi sína noma okusongela ukuphila uma kuthathwe kanye nama-anticoagulants (’ama-thinner egazi’) njenge-warfarin (i-Coumadin^®). Tshela udokotela wakho uma uthatha i-warfarin. Udokotela wakho uzo-oda ukuhlolwa kwelabhoratri ukuqapha ukuthi igazi lakho ligcina ngokushesha kangakanani futhi kungadingeka ukuthi ushintshe umthamo wakho we-warfarin. Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: ukopha okungavamile; ukuphalaza noma ukuphalaza igazi noma okokusansundu okufana nezindawo zekhofi; ezinegazi noma ezimnyama, izitulo zokulinda; igazi emchameni; umchamo obomvu noma onsundu; noma ukulinyazwa okulula.

ICapecitabine isetshenziswa ngokuhlangana neminye imithi yokwelapha umdlavuza webele obuyile ngemuva kokwelashwa neminye imithi. Iphinde isetshenziswe yodwa ukwelapha umdlavuza webele ongazange uthuthuke ngemuva kokwelashwa ngeminye imithi. ICapecitabine ibuye isetshenziselwe ukwelapha umdlavuza wekoloni noma we-rectal (umdlavuza oqala emathunjini amakhulu) osekubi kakhulu noma usakazeka kwezinye izingxenye zomzimba. Ibuye isetshenziselwe ukuvimbela umdlavuza wekoloni ukuthi ungasakazeki kubantu abahlinzwa ukuze kususwe isimila. ICapecitabine isekilasini lemithi ebizwa ngama-antimetabolites. Isebenza ngokumisa noma ukunciphisa ukukhula kwamangqamuzana omdlavuza.

ICapecitabine iza njengethebhulethi ezothathwa ngomlomo. Imvamisa kuthathwa kabili ngosuku (ekuseni nakusihlwa) amasonto ama-2, kulandelwe ikhefu lesonto eli-1 ngaphambi kokuphinda umjikelezo wesilinganiso olandelayo. Imvamisa kuthathwa ngemuva kokudla (kungakapheli imizuzu engama-30 ibhulakufesi nesidlo sakusihlwa) kanye nengilazi yamanzi. Udokotela wakho uzonquma ukuthi kufanele uwuphindaphinde kangaki lo mjikelezo. Thatha i-capecitabine ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-capecitabine njengoba nje kuqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho. Udokotela wakho angalungisa umthamo wakho we-capecitabine noma ayeke ukwelashwa kwakho isikhathi esithile ngokuya ngempendulo yakho ekwelashweni nanoma yimiphi imiphumela emibi oyitholayo. Khuluma nodokotela wakho mayelana nokuthi uzizwa kanjani ngesikhathi sokwelashwa kwakho.

Gwinya wonke amaphilisi; ungawahlukanisi, ungawahlafune noma uwagxoze.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

ICapecitabine nayo kwesinye isikhathi isetshenziselwa ukwelapha umdlavuza osesiswini (umdlavuza wesisu). Khuluma nodokotela wakho ngezingozi zokusebenzisa lo muthi ngesimo sakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-capecitabine,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-capecitabine, i-fluorouracil (i-Adrucil, i-5-FU), noma imiphi eminye imithi, noma iziphi izithako ezikumaphilisi e-capecitabine. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi uyayisho imishanguzo ebhalwe esigabeni ESIBALULEKILE SEXWAYISO nakokulandelayo: i-phenytoin (Dilantin), leucovorin, ne-folic acid (kuma-multivitamini). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo nayo ingaxhumana ne-capecitabine, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho nalawo angaveli kulolu hlu.
• Tshela udokotela wakho uma utshelwe ukuthi unayo noma wake waba ne-dihydropyrimidine dehydrogenase (DPD) yokushoda kwe-enzyme (ukuntuleka kwe-enzyme eyenzeka ngokwemvelo emzimbeni wakho). Udokotela wakho kungenzeka akutshele ukuthi ungathathi i-capecitabine.
• utshele udokotela wakho uma uke waba nesifo sezinso, isibindi noma senhliziyo.
• utshele udokotela wakho uma ukhulelwe noma uhlela ukukhulelwa. Akufanele uhlele ukuba nezingane ngenkathi uthatha i-capecitabine. Kufanele usebenzise indlela ethembekile yokulawula ukubeletha ukuvimbela ukukhulelwa kuwe noma kumlingani wakho ngesikhathi sokwelashwa kwakho nge-capecitabine. ICapecitabine ingalimaza umbungu. Utshele udokotela wakho uma uncelisa ibele. Akufanele uncelise ibele ngesikhathi sokwelashwa kwakho nge-capecitabine.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Yeqa umthamo ophuthelwe bese uqhubeka nesimiso sakho sokulinganisa esivamile. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

ICapecitabine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ubuhlungu besisu noma isisu esibuhlungu
• ukuqunjelwa
• ukulahlekelwa isifiso sokudla
• shintsha emandleni okunambitha ukudla
• ukoma okwandisiwe
• ukukhathala okungajwayelekile noma ubuthakathaka
• isiyezi
• ikhanda
• ukulahleka kwezinwele
• ukuqubuka kwesikhumba
• emuva, ujoyine, noma ubuhlungu bemisipha
• amehlo abomvu, avuvukile, alumayo noma anezinyembezi
• unenkinga yokulala noma ukuhlala ulele

Eminye imiphumela emibi ingaba mibi.Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:

• isifo sohudo
• isicanucanu
• ukuhlanza
• izilonda emlonyeni
• ukuvuvukala, ubuhlungu, ubomvu, noma ukuxebuka kwesikhumba ezintendeni zezandla nasematheni ezinyawo
• umkhuhlane, amakhaza, umphimbo obuhlungu, noma ezinye izimpawu zokutheleleka
• ukuvuvukala kwezandla, izinyawo, amaqakala, noma imilenze engezansi
• ubuhlungu besifuba noma ingcindezi
• ukushaya kwenhliziyo okusheshayo
• umchamo omnyama
• ukuphuzi kwesikhumba noma kwamehlo

ICapecitabine ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka:

• isifo sohudo
• isicanucanu
• ukuhlanza
• ubuhlungu besisu
• umkhuhlane, amakhaza, umphimbo obuhlungu, noma ezinye izimpawu zokutheleleka
• emnyama, izitulo zokubambezeleka
• umchamo obomvu
• ukulimaza noma ukopha okungavamile
• ukukhathala okungajwayelekile noma ubuthakathaka

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ku-capecitabine.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Xeloda^®