Ukuhlolwa kwe-Aldolase

-Delile

• Yini i-aldolase?
• Kungani ukuhlolwa kwe-aldolase kuyaliwe?
• Kwenziwa kanjani ukuhlolwa kwe-aldolase?
• Ziyini izingozi zokuhlolwa kwe-aldolase?
• Usilungiselela kanjani isivivinyo se-aldolase?
• Isho ukuthini imiphumela yokuhlolwa?
• Amazinga aphezulu noma angajwayelekile e-aldolase
• Amazinga aphansi e-aldolase

Yini i-aldolase?

Umzimba wakho uguqula uhlobo lukashukela olubizwa nge-glucose lube ngamandla. Le nqubo idinga izinyathelo eziningi ezahlukahlukene. Ingxenye eyodwa ebalulekile kule nqubo i-enzyme eyaziwa ngokuthi i-aldolase.

I-Aldolase itholakala kuwo wonke umzimba, kepha ukugxila kuphezulu kakhulu emisipheni yamathambo nasesibindi.

Yize kungekho ukuhlangana okuqondile, amazinga aphezulu e-aldolase egazini angenzeka uma kukhona ukulimala kwemisipha yakho noma isibindi.

Kungani ukuhlolwa kwe-aldolase kuyaliwe?

Ukuhlolwa kwe-aldolase kukala inani le-aldolase egazini lakho. Amazinga akhuphukile ale enzyme angakhombisa inkinga enkulu yempilo.

I-aldolase ephakeme ngokuvamile iwuphawu lokulimala kwemisipha noma kwesibindi. Isibonelo, ukulimala kwemisipha okuvela ekuhlaselweni yinhliziyo kukhipha i-aldolase ngobuningi. Ukulimala kwesibindi, njenge-hepatitis noma i-cirrhosis, kuphakamisa namazinga e-aldolase.

Esikhathini esedlule, ukuhlolwa kwe-aldolase kwakusetshenziselwa ukubheka ukulimala kwesibindi noma kwemisipha. Namuhla, odokotela basebenzisa ukuhlolwa kwegazi okuningana, kufaka phakathi:

• i-creatine kinase (CK)
• i-alanine aminotransferase (ALT)
• i-aspartate aminotransferase (AST)

Ukuhlolwa kwe-aldolase akusasetshenziswa ngokujwayelekile. Kodwa-ke, ingahle i-odolwe uma une-muscular dystrophy.

Ingasetshenziswa futhi ukuhlola ukuphazamiseka okungajwayelekile kofuzo kwemisipha yamathambo, njenge-dermatomyositis ne-polymyositis (PM).

Kwenziwa kanjani ukuhlolwa kwe-aldolase?

Ukuhlolwa kwe-aldolase ukuhlolwa kwegazi, ngakho-ke kuzodingeka unikeze isampula segazi. Isampula ivame ukuthathwa uchwepheshe.

Ukuze bathathe lesi sampuli, bafaka inaliti emthanjeni wengalo noma yesandla sakho bese beqoqa igazi elisesiphungweni. Isampula bese lithunyelwa elebhu ukuze lihlaziywe bese imiphumela ibikwa kudokotela wakho, ozoyibuyekeza nawe.

Ziyini izingozi zokuhlolwa kwe-aldolase?

Ungahle uzwe ukungakhululeki okuthile, okufana nobuhlungu esizeni sokuhlola, lapho kudwetshwa isampula segazi. Kungase kube khona nobuhlungu obufushane, obuncane noma obushisayo esizeni ngemuva kokuhlolwa.

Ngokuvamile, izingozi zokuhlolwa kwegazi zincane. Izingozi ezingaba khona zifaka:

• ubunzima bokuthola isampula, okuholela kuzinti eziningi zezinaliti
• ukopha ngokweqile endaweni yenaliti
• ukuquleka ngenxa yokopha
• ukuqoqwa kwegazi ngaphansi kwesikhumba, okwaziwa njenge-hematoma
• ukutheleleka lapho isikhumba siphuke khona ngenaliti

Usilungiselela kanjani isivivinyo se-aldolase?

Udokotela wakho uzokutshela ukuthi ungakulungiselela kanjani ukuhlolwa. Ngokuvamile, ngeke ukwazi ukudla noma ukuphuza noma yini amahora ayisithupha kuya kwayi-12 ngaphambi kokuhlolwa. Thola izeluleko ezengeziwe ngokuzila ukudla ngaphambi kokuhlolwa kwegazi.

Kubalulekile ukuqaphela ukuthi ukuvivinya umzimba kungathinta imiphumela yokuhlolwa kwe-aldolase. Vumela udokotela wakho azi ngohlelo lwakho lokuzivocavoca njalo. Ungatshelwa ukuthi unciphise ukuzivocavoca izinsuku ezimbalwa ngaphambi kokuhlolwa, ngoba ukuzivocavoca umzimba kungadala ukuthi ube nemiphumela ephezulu yesikhashana ye-aldolase.

Udokotela wakho futhi angakucela ukuthi uyeke ukuthatha imishanguzo engashintsha imiphumela yokuhlolwa. Qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo. Lokhu kufaka phakathi kokubili imithi kadokotela kanye ne-over-the-counter (OTC).

Isho ukuthini imiphumela yokuhlolwa?

Ububanzi obuthile besivivinyo esingajwayelekile bungahluka kancane nge-laboratory, futhi kukhona umehluko omncane phakathi kwamazinga ajwayelekile abesilisa nabesifazane.

Ngokuvamile, imiphumela ejwayelekile ingaba phakathi kwamayunithi ayi-1.0 iye kwangama-7.5 ilitha ngayinye (U / L) yabantu abaneminyaka engu-17 kuya phezulu. Imiphumela ejwayelekile yabantu abafinyelela eminyakeni engu-16 ingafinyelela ku-14.5 U / L.

Amazinga aphezulu noma angajwayelekile e-aldolase

Amazinga aphezulu noma angajwayelekile angaba ngenxa yezimo zezempilo, kufaka phakathi:

• ukulimala kwemisipha
• isikhumba
• i-hepatitis yegciwane
• umdlavuza wesibindi, amanyikwe, noma indlala yesinye
• ukuqina kwemisipha
• isifo senhliziyo
• i-polymyositis
• i-leukemia
• isilonda esibhibhayo

Ukuhlolwa kwe-Aldolase kwezimo ezibangela amazinga aphezulu e-aldolase (hyperaldolasemia) akuqondile. Izimo noma izifo ezibangela ukwehla kwemisipha kungaholela ku-hyperaldolasemia. Ekuqaleni, ukubhujiswa kwemisipha kubangela amazinga aphezulu e-aldolase. Kodwa-ke, amazinga e-aldolase empeleni ancipha njengoba inani lemisipha emzimbeni lincipha.

Yazisa udokotela wakho uma usanda kuhlanganyela emsebenzini okhandlayo, ongadala ukuthi ube nemiphumela ephakeme okwesikhashana noma edukisayo.

Amazinga aphansi e-aldolase

Ngaphansi kuka-2.0 kuya ku-3.0 U / L kuthathwa njengezinga eliphansi le-aldolase. Amaleveli aphansi e-aldolase angabonakala kubantu abane:

• ukungabekezelelani kwe-fructose
• isifo sokuqeda imisipha
• sekwephuzile muscular dystrophy