Umlobi: William Ramirez
Usuku Lokudalwa: 15 Usepthemba 2021
Ukuvuselela Usuku: 14 Unovemba 2024
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Plasma proteins and Prothrombin time: LFTs: Part 4
Ividiyo: Plasma proteins and Prothrombin time: LFTs: Part 4

-Delile

Kuyini ukuhlolwa kwe-alpha-1 antitrypsin (AAT)?

Lokhu kuhlolwa kukala inani le-alpha-1 antitrypsin (AAT) egazini. I-AAT yiprotheni eyenziwe esibindini. Kuyasiza ukuvikela amaphaphu akho ekulimaleni nasezifweni, njenge-emphysema nesifo esingapheliyo se-pulmonary disease (COPD).

I-AAT yenziwa izakhi zofuzo ezithile emzimbeni wakho. Izakhi zofuzo ziyizakhi eziyisisekelo zofuzo ezidluliswe zivela kubazali bakho. Ziphethe imininingwane enquma izici zakho ezihlukile, njengokuphakama nombala wamehlo. Wonke umuntu uzuza amakhophi amabili wesakhi esenza i-AAT, elilodwa livela kuyise elinye likumama wakhe. Uma kukhona ukuguquka (ushintsho) kwelinye noma womabili amakhophi alesi sakhi, umzimba wakho uzokwenza i-AAT noma i-AAT encane engasebenzi ngendlela efanele.

  • Uma unamakhophi amabili aguqukile wesakhi, kusho ukuthi unesimo esibizwa ngokushoda kwe-AAT. Abantu abanalesi sifo basengozini enkulu yokuthola isifo samaphaphu noma ukulimala kwesibindi ngaphambi kweminyaka engama-45.
  • Uma unegciwane elilodwa eliguqukile le-AAT, ungahle ube nezilinganiso eziphansi kunezinga elijwayelekile le-AAT, kodwa izimpawu zesifo zibe mnene noma zingabi bikho. Abantu abanegciwane elilodwa eliguqukile bangabathwali bokushoda kwe-AAT. Lokhu kusho ukuthi awunaso isimo, kepha ungadlulisela isakhi sofuzo esiguquliwe ezinganeni zakho.

Ukuhlolwa kwe-AAT kungasiza ekuboniseni uma unokuguquka kwezakhi zofuzo okukubeka engcupheni yezifo.


Amanye amagama: Ukushoda kwe-A1AT, AAT, alpha-1-antiprotease, α1-antitrypsin

Kusetshenziselwa ini?

Ukuhlolwa kwe-AAT kuvame ukusetshenziselwa ukusiza ukuthola ukuntuleka kwe-AAT kubantu ababa nesifo samaphaphu besebancane (iminyaka engama-45 noma ngaphansi) futhi abanazo ezinye izinto eziyingozi njengokubhema.

Ukuhlolwa kungasetshenziselwa ukuxilonga uhlobo olungavamile lwesifo sesibindi ezinganeni.

Kungani ngidinga ukuhlolwa kwe-AAT?

Ungadinga ukuhlolwa kwe-AAT uma ungaphansi kweminyaka engama-45, awubhemi, futhi unezimpawu zesifo samaphaphu, kufaka phakathi:

  • Ukuqhuma
  • Ukuphelelwa umoya
  • Ukukhwehlela okungapheli
  • Kushesha kunokushaya kwenhliziyo okuvamile lapho usukuma
  • Izinkinga zombono
  • I-asthma engaphenduli kahle ekwelashweni

Ungase futhi uthole lolu vivinyo uma unomlando womndeni wokushoda kwe-AAT.

Ukushoda kwe-AAT ezinganeni kuvame ukuthinta isibindi. Ngakho-ke ingane yakho ingadinga ukuhlolwa kwe-AAT uma umhlinzeki wayo wezempilo ethola izimpawu zesifo sesibindi. Lokhu kufaka phakathi:


  • I-jaundice, ukuphuzi kwesikhumba namehlo okuhlala isikhathi esingaphezu kwesonto noma amabili
  • Ubende obukhulisiwe
  • Ukulunywa njalo

Kwenzekani ngesikhathi sokuhlolwa kwe-AAT?

Uchwepheshe wezempilo uzothatha isampula yegazi emthanjeni osengalweni yakho, esebenzisa inaliti encane. Ngemuva kokuthi kufakwe inaliti, kuzoqoqwa inani elincane legazi kufakwe ithubhu yokuhlola noma isitsha. Ungase uzizwe uluma kancane lapho inaliti ingena noma iphuma. Lokhu ngokuvamile kuthatha imizuzu engaphansi kwemihlanu.

Ngabe kukhona engizodinga ukukwenza ukulungiselela isivivinyo?

Awudingi amalungiselelo akhethekile wokuhlolwa kwe-AAT.

Ingabe zikhona izingozi esivivinyweni?

Kunobungozi obuncane kakhulu bokuhlolwa kwegazi. Ungaba nobuhlungu obuncane noma ukulimaza lapho kufakwe khona inaliti, kepha izimpawu eziningi ziyaphela ngokushesha.

Isho ukuthini imiphumela?

Uma imiphumela yakho ikhombisa inani eliphansi kunejwayelekile le-AAT, kungenzeka ukuthi kusho ukuthi unofuzo olulodwa noma ezimbili eziguquliwe ze-AAT. Ukwehla kwezinga, maningi amathuba okuba unezakhi zofuzo ezimbili eziguquliwe kanye nokushoda kwe-AAT.


Uma kutholakala ukuthi unenkinga ye-AAT, ungathatha izinyathelo zokunciphisa ubungozi besifo. Lokhu kufaka phakathi:

  • Ukungabhemi. Uma ubhema, yeka ukubhema. Uma ungabhemi, ungaqali. Ukubhema yikho okuholela engcupheni yesifo samaphaphu esisongela ukuphila kubantu abanenkinga ye-AAT.
  • Ukulandela ukudla okunempilo
  • Ukuvivinya umzimba njalo
  • Ukubona umhlinzeki wakho wezokunakekelwa kwempilo njalo
  • Ukuthatha imithi njengokuyalelwa ngumhlinzeki wakho

Uma unemibuzo ngemiphumela yakho, khuluma nomhlinzeki wakho wezokunakekelwa kwempilo.

Funda kabanzi mayelana nokuhlolwa kwelabhorethri, ububanzi bezinkomba, nemiphumela yokuqonda.

Ngabe kukhona okunye engidinga ukukwazi mayelana nokuhlolwa kwe-AAT?

Ngaphambi kokuvuma ukuhlolwa, kungasiza ukukhuluma nomeluleki wezofuzo. Umeluleki wezofuzo uchwepheshe oqeqeshwe ngokukhethekile kwezofuzo nasekuhloleni izakhi zofuzo. Umeluleki angakusiza uqonde ubungozi nezinzuzo zokuhlolwa. Uma uhlolwe, umeluleki angakusiza uqonde imiphumela futhi unikeze imininingwane ngesimo, kufaka phakathi ubungozi bokudlulisela lesi sifo ezinganeni zakho.

Izinkomba

  1. Ukuhlolwa Kwelebhu Ku-inthanethi [i-Intanethi]. IWashington DC: I-American Association for Clinical Chemistry; c2001–2019. I-Alpha-1 Antitrypsin; [kubuyekezwe i-2019 Jun 7; kucashunwe ngo-2019 Okthoba 1]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://labtestsonline.org/tests/alpha-1-antitrypsin
  2. Ukuhlolwa Kwelebhu Ku-inthanethi [i-Intanethi]. IWashington DC: I-American Association for Clinical Chemistry; c2001–2019. I-jaundice; [kubuyekezwe 2018 Feb 2; kucashunwe ngo-2019 Okthoba 1]; [cishe izikrini ezi-3]. Kutholakala kusuka: https://labtestsonline.org/conditions/jaundice
  3. Uhlobo Lokuthengwa Kwamakhasimende we-Merck [Internet]. IKenilworth (NJ): IMerck & Co Inc .; c2019. Ukushoda kwe-Alpha-1 Antitrypsin; [kubuyekezwe u-2018 Nov; kucashunwe ngo-2019 Okthoba 1]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://www.merckmanuals.com/home/lung-and-airway-disorders/chronic-obstructive-pulmonary-disease-copd/alpha-1-antitrypsin-deficiency?query=alpha-1%20antitrypsin
  4. I-National Heart, Lung, ne-Blood Institute [i-Intanethi]. I-Bethesda (MD): UMnyango Wezempilo kanye Nezinsizakalo Zabantu e-U.S. Ukushoda kwe-Alpha-1 Antitrypsin; [kucashunwe ngo-2019 Oct 1]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://www.nhlbi.nih.gov/health-topics/alpha-1-antitrypsin-deficiency
  5. I-National Heart, Lung, ne-Blood Institute [i-Intanethi]. I-Bethesda (MD): UMnyango Wezempilo kanye Nezinsizakalo Zabantu e-U.S. Ukuhlolwa Kwegazi; [kucashunwe ngo-2019 Oct 1]; [cishe izikrini ezi-3]. Kutholakala kusuka: https://www.nhlbi.nih.gov/health-topics/blood-tests
  6. I-NIH U.S. National Library of Medicine: Isethenjwa Sasekhaya se-Genetics [Internet]. I-Bethesda (MD): UMnyango Wezempilo kanye Nezinsizakalo Zabantu e-U.S. Luyini ufuzo ?; I-2019 Oct 1 [icashunwe ngo-2019 Oct 1]; [cishe izikrini ezi-3]. Kutholakala kusuka: https://ghr.nlm.nih.gov/primer/basics/gene
  7. Impilo ye-UF: University of Florida Health [Internet]. IGainesville (FL): Inyuvesi yaseFlorida Impilo; c2019. Ukuhlolwa kwegazi kwe-Alpha-1 antitrypsin: Ukubuka konke; [kubuyekezwe i-2019 Oct 1; kucashunwe ngo-2019 Okthoba 1]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://ufhealth.org/alpha-1-antitrypsin-blood-test
  8. I-University of Rochester Medical Center [i-Inthanethi]. URochester (NY): Isikhungo Sezokwelapha sase-University of Rochester; c2019. I-Health Encyclopedia: I-Alpha-1 Antitrypsin; [kucashunwe ngo-2019 Oct 1]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=alpha_1_antitrypsin
  9. I-UW Health [Inthanethi]. UMadison (WI): Izibhedlela zase-University of Wisconsin kanye neGunya Lemitholampilo; c2019. Ukuhlolwa kwe-Alpha-1 Antitrypsin Genetic: Kuyini Ukushoda kwe-Alpha-1 Antitrypsin ?; [kubuyekezwe i-2018 Sep 5; kucashunwe ngo-2019 Okthoba 1]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://www.uwhealth.org/health/topic/special/alpha-1-antitrypsin-deficiency-genetic-testing/uf6753.html
  10. I-UW Health [Inthanethi]. UMadison (WI): Izibhedlela zase-University of Wisconsin kanye neGunya Lemitholampilo; c2019. Ukuhlolwa kwe-Alpha-1 Antitrypsin Genetic: Kuyini Ukwelulekwa Ngokofuzo ?; [kubuyekezwe i-2018 Sep 5; kucashunwe ngo-2019 Okthoba 1]; [cishe izikrini eziyi-7]. Kutholakala kusuka: https://www.uwhealth.org/health/topic/special/alpha-1-antitrypsin-deficiency-genetic-testing/uf6753.html#tv8548
  11. I-UW Health [Inthanethi]. UMadison (WI): Izibhedlela zase-University of Wisconsin kanye neGunya Lemitholampilo; c2019. Ukuhlolwa kwe-Alpha-1 Antitrypsin Genetic: Kungani Ngingahloli ?; [kubuyekezwe i-2018 Sep 5; kucashunwe ngo-2019 Okthoba 1]; [cishe izikrini eziyi-6]. Kutholakala kusuka: https://www.uwhealth.org/health/topic/special/alpha-1-antitrypsin-deficiency-genetic-testing/uf6753.html#uf6790

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