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Kuyini ukuhlolwa kwegazi kwe-ALT?

I-ALT, emele i-alanine transaminase, iyi-enzyme etholakala ikakhulu esibindini. Lapho amaseli wesibindi elimele, akhipha i-ALT egazini. Ukuhlolwa kwe-ALT kukala inani le-ALT egazini. Izinga eliphakeme le-ALT egazini lingakhombisa inkinga yesibindi, ngisho nangaphambi kokuba ube nezimpawu zesifo sesibindi, njenge-jaundice, isimo esidala ukuthi isikhumba namehlo akho abe phuzi. Ukuhlolwa kwegazi le-ALT kungasiza ekutholeni kusenesikhathi isifo sesibindi.

Amanye amagama: Alanine Transaminase (ALT), SGPT, Serum Glutamic-Pyruvic Transaminase, GPT

Kusetshenziselwa ini?

Ukuhlolwa kwegazi kwe-ALT uhlobo lokuhlolwa kokusebenza kwesibindi. Ukuhlolwa kokusebenza kwesibindi kungaba yingxenye yokuhlolwa okujwayelekile. Ukuhlolwa kungasiza futhi ukuxilonga izinkinga zesibindi.

Kungani ngidinga ukuhlolwa kwegazi le-ALT?

Umhlinzeki wakho wokunakekelwa kwezempilo kungenzeka ukuthi u-ode ukuhlolwa kwesibindi, kufaka phakathi ukuhlolwa kwegazi kwe-ALT, njengengxenye yokuhlolwa okujwayelekile noma uma unezimpawu zokulimala kwesibindi. Lokhu kungafaka:


  • Isicanucanu nokuhlanza
  • I-jaundice
  • Ubuhlungu besisu
  • Ukuphelelwa isifiso sokudla
  • Ukulunywa okungavamile
  • Ukukhathala

Ngenxa yokuthi i-ALT esegazini ingabonisa ukulimala kwesibindi ngaphambi kokuba kuvele izimpawu, umhlinzeki wakho wezokunakekelwa kwempilo anga-oda ukuhlolwa kwegazi le-ALT uma usengozini enkulu yokulimala kwesibindi. Izici eziyingozi zesifo sesibindi zifaka:

  • Umlando womndeni wesifo sesibindi
  • Ukuphuza ngokweqile
  • Ukuvezwa noma ukuvezwa okungenzeka kwesifo se-hepatitis
  • Ukukhuluphala ngokweqile
  • Isifo sikashukela
  • Ukuthatha imithi ethile engadala ukulimala kwesibindi

Kwenzekani ngesikhathi sokuhlolwa kwegazi le-ALT?

Uchwepheshe wezempilo uzothatha isampula yegazi emthanjeni osengalweni yakho, esebenzisa inaliti encane.Ngemuva kokuthi kufakwe inaliti, kuzoqoqwa inani elincane legazi kufakwe ithubhu yokuhlola noma isitsha. Ungase uzizwe uluma kancane lapho inaliti ingena noma iphuma. Lokhu ngokuvamile kuthatha imizuzu engaphansi kwemihlanu.

Ngabe kukhona engizodinga ukukwenza ukulungiselela isivivinyo?

Awudingi noma yimaphi amalungiselelo akhethekile okuhlolwa kwegazi le-ALT. Uma umhlinzeki wakho wezokunakekelwa kwempilo eyalele ukuhlolwa okwengeziwe kusampula yegazi lakho, kungadingeka ukuthi uzile ukudla (ungadli noma uphuze) amahora ambalwa ngaphambi kokuhlolwa. Umhlinzeki wakho wezokunakekelwa kwempilo uzokwazisa uma ngabe kukhona imiyalelo ekhethekile ongayilandela.


Ingabe zikhona izingozi esivivinyweni?

Kunengozi encane kakhulu yokuhlolwa kwegazi. Ungaba nobuhlungu obuncane noma ukulimaza lapho kufakwe khona inaliti, kepha izimpawu eziningi ziyaphela ngokushesha.

Isho ukuthini imiphumela?

Ukuhlolwa kwegazi kwe-ALT kuvame ukuba yingxenye yokuhlolwa kokusebenza kwesibindi. Ukuhlolwa kokusebenza kwesibindi kukala amaprotheni ahlukahlukene, izinto, nama-enzyme futhi kungacacisa ukuthi isibindi sakho sisebenza kahle kangakanani. Umhlinzeki wakho wokunakekelwa kwezempilo angaqhathanisa imiphumela yakho ye-ALT nemiphumela yezinye izivivinyo zesibindi ukusiza ukufunda kabanzi ngokusebenza kwesibindi sakho. Amazinga aphezulu e-ALT angabonisa ukulimala kwesibindi kusuka ku-hepatitis, ukutheleleka, i-cirrhosis, umdlavuza wesibindi, noma ezinye izifo zesibindi.

Ezinye izinto, kufaka phakathi imithi, zingathinta imiphumela yakho. Qiniseka ukuthi utshela umhlinzeki wakho wezokunakekelwa kwempilo mayelana nayo yonke imishanguzo kadokotela oyisebenzisayo kanye namaphilisi owathethayo.

Funda kabanzi mayelana nokuhlolwa kwelabhorethri, ububanzi bezinkomba, nemiphumela yokuqonda.

Ngabe kukhona okunye engidinga ukukwazi ngokuhlolwa kwegazi le-ALT?

I-ALT yayijwayele ukubizwa nge-SGPT, emele i-serum glutamic-pyruvic transaminase. Ukuhlolwa kwegazi kwe-ALT ngaphambili kwakwaziwa ngokuthi ukuhlolwa kwe-SGPT.


Izinkomba

  1. I-American Liver Foundation. [Inthanethi]. ENew York: I-American Liver Foundation; c2017. Ukuhlolwa Komsebenzi Wesibindi; [kubuyekezwe 2016 Jan 25; kukhonjiwe ngo-2017 Mar 18]; [cishe izikrini ezi-3]. Kutholakala ku: http://www.liverfoundation.org/abouttheliver/info/liverfunctiontests/
  2. UHinkle J, Cheever K. Brunner & Suddarth's Handbook of Laboratory and Diagnostic Test. 2nd Ed, Kindle. IPhiladelphia: I-Wolters Kluwer Health, Lippincott Williams & Wilkins; c2014. I-Alanine Aminotransferase (ALT); k. 31.
  3. Ukuhlolwa Kwelebhu Ku-inthanethi [i-Intanethi]. IWashington DC: I-American Association for Clinical Chemistry; c2001–2017. ALT: Isivivinyo; [kubuyekezwe 2016 Apr 28; kukhonjiwe ngo-2017 Mar 18]; [cishe izikrini ezi-4]. Kutholakala ku:https://labtestsonline.org/understanding/analytes/alt/tab/test/
  4. Ukuhlolwa Kwelebhu Ku-inthanethi [i-Intanethi]. IWashington DC: I-American Association for Clinical Chemistry; c2001–2017. Iphaneli Yesibindi: Ukuhlolwa; [kubuyekezwe 2016 Mar 10; kukhonjiwe ngo-2017 Mar 18]; [cishe izikrini ezi-4]. Kutholakala ku:https://labtestsonline.org/understanding/analytes/liver-panel/tab/test/
  5. IMayo Clinic [Inthanethi]. IMayo Foundation for Medical Education and Research; c1998–2019. Ama-enzyme wesibindi aphakeme; Uhlolojikelele; 2018 Jan 11 [icashunwe 2019 Jan 31]; [cishe izikrini ezi-3]. Kutholakala ku:https://www.mayoclinic.org/symptoms/elevated-liver-enzymes/basics/causes/sym-20050830
  6. IMayo Clinic [Inthanethi]. IMayo Foundation for Medical Education and Research; c1998–2017. Isifo sesibindi: Sibutsetelo; 2014 Jul 15 [icashunwe ngo-2017 Mar 18]; [cishe izikrini ezi-3]. Kutholakala ku:http://www.mayoclinic.org/diseases-conditions/liver-problems/basics/risk-factors/con-20025300
  7. Isikhungo Somdlavuza se-MD Anderson [i-Intanethi]. I-Houston: I-University of Texas MD Anderson Cancer Center; c2019. Uhlolojikelele; 2018 Jan 11 [icashunwe 2019 Jan 31]; [cishe izikrini ezi-3]. Kutholakala ku:https://www.mdanderson.org/newsroom/common-medical-screen-predicts-liver-cancer-risk-in-general-popu.h00-158754690.html
  8. I-National Heart, Lung, ne-Blood Institute [i-Intanethi]. I-Bethesda (MD): UMnyango Wezempilo kanye Nezinsizakalo Zabantu e-U.S. Ziyini Izingozi Zokuhlolwa Kwegazi ?; [kubuyekezwe 2012 Jan 6; kukhonjiwe ngo-2017 Mar 18]; [cishe izikrini eziyi-6]. Kutholakala ku:https://www.nhlbi.nih.gov/health-topics/blood-tests#Risk-Factors
  9. I-National Heart, Lung, ne-Blood Institute [i-Intanethi]. I-Bethesda (MD): UMnyango Wezempilo kanye Nezinsizakalo Zabantu e-U.S. Ongakulindela Nezivivinyo Zegazi; [kubuyekezwe 2012 Jan 6; kukhonjiwe ngo-2017 Mar 18]; [cishe izikrini ezi-5]. Kutholakala ku:https://www.nhlbi.nih.gov/health-topics/blood-tests
  10. I-University of Rochester Medical Center [i-Inthanethi]. URochester (NY): Isikhungo Sezokwelapha sase-University of Rochester; c2017. I-Health Encyclopedia: ALT; [kucashunwe ngo-2017 Mar 18]; [cishe izikrini ezi-2]. Kutholakala ku:https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid;=alt_sgpt

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