Konke Okudingeka Ukwazi Ngezifo Ezicindezelayo Ezenza Isisindo Sizuze

-Delile

• 1. Ama-anti-depressants e-Tricyclic
• 2. Amanye ama-monoamine oxidase inhibitors (ama-MAOIs)
• 3.Ukusetshenziswa kwesikhathi eside kwama-serotonin reuptake inhibitors (SSRIs) akhethiwe athile
• 4. Amanye ama-anti-depressants angajwayelekile
• Ama-anti-depressants angenamathuba amancane okudala ukuzuza kwesisindo
• Ukuthatha

Ukubuka konke

Ukuzuza kwesisindo kungumphumela ongaba khona wemithi eminingi elwa nokudangala. Ngenkathi umuntu ngamunye esabela ekwelashweni kwe-anti-depressant ngokuhlukile, ama-anti-depressants alandelayo angahle abe nethuba lokuthola isisindo ngesikhathi sokwelashwa kwakho.

1. Ama-anti-depressants e-Tricyclic

Ama-antidepressants e-Tricyclic, awaziwa nangokuthi ama-cyclic antidepressants noma ama-TCA, angadala ukuzuza kwesisindo. Le mithi ihlanganisa:

• i-amitriptyline (u-Elavil)
• yerlisikisi
• i-desipramine (Norpramin)
• i-doxepin (Adapin)
• imipramine (Tofranil-PM)
• i-nortriptyline (Pamelor)
• i-protriptyline (Vivactil)
• i-trimipramine (iSurmontil)

Ama-TCA ngezinye zezidakamizwa zokuqala ezivunyelwe ukwelapha ukucindezeleka. Azisabekwa kaningi ngoba ukwelashwa okusha kubangela imiphumela emibi embalwa.

Ukuzuza isisindo kwakuyisizathu esivamile sokuthi abantu bayeke ukwelashwa ngalezi zinhlobo ze-anti-depressants, ngokusho kocwaningo luka-1984.

Noma kunjalo, ama-TCAs angasebenza kubantu abangaphenduli kwezinye izinhlobo zemithi elwa nokudangala, naphezu kwemiphumela emibi engafuneki.

2. Amanye ama-monoamine oxidase inhibitors (ama-MAOIs)

I-Monoamine oxidase inhibitors (MAOIs) bekuyisigaba sokuqala semithi elwa nokucindezelwa okufanele yenziwe. Ama-MAOIs abangela ukuzuza kwesisindo afaka:

• i-phenelzine (Nardil)
• isocarboxazid (Marplan)
• i-tranylcypromine (iParnate)

Odokotela banquma ama-MAOIs kaningi lapho amanye ama-anti-depressants engasebenzi ngenxa yemiphumela ethile emibi kanye nokukhathazeka kokuphepha. Kuma-MAOI amathathu abhalwe ngenhla, i-phenelzine iyona engaba nomphumela wokuzuza kwesisindo, ngokusho kuka-1988.

Kodwa-ke, ukwakheka okusha kwe-MAOI eyaziwa ngokuthi i-selegiline (i-Emsam) kukhonjisiwe ukuthi kuholele ekulahlekelweni kwesisindo ngesikhathi sokwelashwa. I-Emsam ngumuthi we-transdermal osetshenziswa esikhumbeni nge-patch.

3.Ukusetshenziswa kwesikhathi eside kwama-serotonin reuptake inhibitors (SSRIs) akhethiwe athile

Ama-SSRI yisigaba esinqunyelwe kakhulu semithi yokudangala. Ukusetshenziswa kwesikhathi eside kwama-SSRI alandelayo kungadala ukuzuza kwesisindo:

• i-paroxetine (Paxil, Pexeva, Brisdelle)
• i-sertraline (Zoloft)
• i-fluoxetine (Prozac)
• I-citalopram (Celexa)

Yize amanye ama-SSRI ehlotshaniswa nokwehlisa isisindo ekuqaleni, ukusetshenziswa kwesikhathi eside kwama-SSRI kuhlotshaniswa kakhulu nokuzuza kwesisindo. Ukusetshenziswa kwesikhathi eside kubhekwa njengokwelashwa okuhlala isikhathi eside kunezinyanga eziyisithupha.

Kuma-SSRI abhalwe ngenhla, i-paroxetine ivame ukuhlotshaniswa nokuzuza kwesisindo ngokusetshenziswa kwesikhathi eside nangesikhathi esifushane.

4. Amanye ama-anti-depressants angajwayelekile

IMirtazapine (Remeron) umphikisi we-noradrenergic, okuwuhlobo lwe-atypical antidepressant. Lesi sidakamizwa bekulokhu kungenzeka ukuthi sidale ukuzuza kwesisindo futhi sandise isifiso sokudla kunezinye izidakamizwa.

IMirtazapine mancane amathuba okuthi yenze abantu bakhuluphele uma kuqhathaniswa nama-TCA.

Futhi akuholeli eminye imiphumela emibi njengamanye ama-anti-depressants. Noma kunjalo, kungadala:

• isicanucanu
• ukuhlanza
• ukungasebenzi ngokocansi

Ama-anti-depressants angenamathuba amancane okudala ukuzuza kwesisindo

Amanye ama-anti-depressants ahlotshaniswa nokuzuza kwesisindo esincane njengomphumela wecala. Lezi zidambisi-mkhuba zibandakanya:

• escitalopram (Lexapro, Cipralex), i-SSRI
• I-duloxetine (Cymbalta), i-serotonin-norepinephrine reuptake inhibitor (SNRI), ingadala ukuzuza kwesisindo
• i-bupropion (i-Wellbutrin, i-Forfivo, ne-Aplenzin), i-antidepressant engajwayelekile
• nefazodone (Serzone), umphikisi we-serotonin kanye ne-reuptake inhibitor
• i-venlafaxine (i-Effexor) ne-venlafaxine ER (i-Effexor XR), womabili angama-SNRIs
• desvenlafaxine (Pristiq), i-SNRI
• levomilnacipran (Fetzima), iSNRI
• i-vilazodone (i-Viibryd), i-serotonergic antidepressant
• i-vortioxetine (i-Trintellix), i-antidepressant engajwayelekile
• selegiline (Emsam), i-MAOI entsha oyifaka esikhunjeni sakho, engaholela emiphumeleni emibi embalwa kunama-MAO athathwe ngomlomo

Ukuzuza kwesisindo nakho amathuba okuba kwenzeke ngama-SSRI alandelayo uma esetshenziselwa izinyanga ezingaphansi kwezinyanga eziyisithupha:

• i-sertraline (Zoloft)
• i-fluoxetine (Prozac)
• I-citalopram (Celexa)

Ukuthatha

Akuwona wonke umuntu othatha i-anti-depressant ozoba nesisindo. Abanye abantu empeleni bazoncipha.

Ochwepheshe bagcizelela ukuthi ukukhathazeka ngokuthola isisindo akufanele kuthinte ukukhetha kwe-antidepressant kubantu abaningi. Kuneminye imiphumela engemihle nezici okufanele uzicabangele lapho ukhetha i-anti-depressant.

Uma uthola isisindo esithile ngenkathi uthatha i-anti-depressant, umuthi kungenzeka ungabi imbangela eqondile yokuthola isisindo. Isimo esithuthukisiwe ngenkathi uthatha i-anti-depressant, isibonelo, singakhuphula ukudla kwakho, okuholele ekuzuzeni isisindo.

Ungayeki ukuthatha umuthi wakho zisuka noma ngabe uthola isisindo esincane. Kuzodingeka usebenze nodokotela wakho ukuthola i-antidepressant esiza ngezimpawu zakho zokudangala futhi engabangeli imiphumela emibi engafuneki. Lokhu kungathatha ukubekezela okuncane.

Udokotela wakho angakunikeza namathiphu wokuvimbela ukuzuza kwesisindo ngenkathi ukwelashwa okucindezelayo.