Ingabe i-CBD iyavela ekuhlolweni kwezidakamizwa?

-Delile

• Kungenzeka yini?
• Ngabe usho ukuthi imikhiqizo ethile ye-CBD ingaqukatha iTHC?
• Yiziphi izinhlobo ezahlukahlukene ze-CBD?
• I-CBD ephelele
• I-CBD ebanzi
• CBD ukuhlukanisa
• Yimalini iTHC okufanele ibe khona ukuze ubhalise ekuhlolweni kwezidakamizwa?
• Umchamo
• Igazi
• Amathe
• Izinwele
• Kungani okunye ukusetshenziswa kwe-CBD kungaholela kumphumela omuhle wokuhlolwa we-THC?
• Ukungcola okuphambene
• Ukuvezwa okwesibili kwe-THC
• Ukubhalwa okungekho emthethweni komkhiqizo
• Ngabe i-CBD ingaphenduka i-THC emzimbeni?
• Ungaqiniseka kanjani ukuthi umkhiqizo we-CBD awunayo i-THC?
• Funda imininingwane yomkhiqizo
• Khetha imikhiqizo ebala inani le-CBD
• Thola ukuthi imikhiqizo ye-hemp eyenziwe nge-hemp ivela kuphi
• Yenza ucwaningo lwakho
• Gwema imikhiqizo eyenza izimangalo ezihlobene nempilo
• Ngakho-ke i-CBD emsulwa ngeke ibhalise ekuhlolweni okujwayelekile kwezidakamizwa?
• Okubalulekile

Kungenzeka yini?

I-Cannabidiol (i-CBD) akufanele ivele ekuhlolweni kwezidakamizwa.

Kodwa-ke, imikhiqizo eminingi ye-CBD ye-delta-9-tetrahydrocannabinol (THC), isithako esiyinhloko sentsangu.

Uma kukhona iTHC eyanele, izovela ekuhlolweni kwezidakamizwa.

Lokhu kusho ukuthi ezimweni ezingavamile, ukusebenzisa i-CBD kungaholela ekuhlolweni okuhle kwezidakamizwa. Konke kuncike kukhwalithi nokwakheka komkhiqizo.

Funda ukuze ufunde ukuthi ungawugwema kanjani umphumela omuhle wokuhlolwa kwezidakamizwa, ukuthi ubheke ini kwimikhiqizo ye-CBD, nokuningi.

Ngabe usho ukuthi imikhiqizo ethile ye-CBD ingaqukatha iTHC?

Imikhiqizo eminingi ye-CBD ayilawulwa yi-Food and Drug Administration (FDA). Ngenxa yalokhu, kunzima ukwazi ukuthi yini ekuzo - noma ngabe le mikhiqizo isemthethweni esifundazweni sakho.

Izici ezinjengokuthi kukhishwa kuphi i-CBD nokuthi kuvunwa kanjani kungenza i-THC ingcoliswe kakhulu. Izinhlobo ezithile ze-CBD mancane amathuba okuthi zibe ne-THC kuzo kunezinye.

Yiziphi izinhlobo ezahlukahlukene ze-CBD?

I-CBD ivela ku-cannabis, umndeni wezitshalo. Izitshalo zensangu ziqukethe amakhulu ezinhlanganisela ezenzeka ngokwemvelo, kufaka phakathi:

• ama-cannabinoids
• ngobe
• ama-flavonoids

Ukwakheka kwawo kwamakhemikhali kuyahlukahluka ngokusho kohlobo lwesitshalo nokuhlukahluka.

Yize insangu nemikhiqizo ye-hemp zombili zitholakala ezitshalweni ze-cannabis, ziqukethe amazinga ahlukile we-THC.

Izitshalo zensangu ngokuvamile ziqukethe i-THC ngokugxila okungafani. I-THC insangu iyona ekhiqiza "okuphezulu" okuhambisana nokubhema noma ukuvuthisa ukhula.

Ngokuphambene nalokho, imikhiqizo eyenziwe nge-hemp iyadingeka ngokomthetho ukuthi iqukathe okungaphansi kokuqukethwe kwe-THC.

Ngenxa yalokho, i-CBD etholakala nge-hemp mancane amathuba okuthi iqukathe i-THC kune-CBD etholakala ngensangu.

Izinhlobonhlobo zezitshalo akuyona ukuphela kwesici. Izindlela zokuvuna nokucwengwa nazo zingashintsha ukuthi yimaphi amakhemikhali avela ku-CBD.

Ukukhishwa kwe-CBD kuvame ukubizwa ngokuthi kungenye yezinhlobo ezilandelayo.

I-CBD ephelele

Ukukhishwa okugcwele kwe-CBD okuqukethe zonke izingxube ezenzeka ngokwemvelo esitshalweni abakhishwe kuso.

Ngamanye amagama, imikhiqizo egcwele iyonke ifaka i-CBD eceleni kwe-terpenes, i-flavonoids, namanye ama-cannabinoids afana ne-THC.

Imikhiqizo ye-CBD egcwele ngokuphelele ikhishwa kuma-subspecies ensangu.

Amafutha e-CBD atholakala ngensangu egcwele angaqukatha amanani ahlukahlukene we-THC.

Ngakolunye uhlangothi, uwoyela we-CBD owenziwe ngokugcwele we-hemp, ngokomthetho kudingeka ukuthi uqukethe ngaphansi kwamaphesenti angu-0.3 i-THC.

Akubona bonke abakhiqizi abadalula ukuthi iziqeshana zabo eziphelele zivelaphi, ngakho-ke kungaba nzima ukuhlola ukuthi i-THC ingaba khona kangakanani kumkhiqizo othile.

I-CBD egcwele i-spectrum iyatholakala kabanzi. Imikhiqizo isukela koyela, okokuxuba, nokudla, kuya kokhilimu nama-serum.

I-CBD ebanzi

Njengemikhiqizo ye-CBD egcwele, imikhiqizo ebanzi ye-CBD iqukethe izinto ezengeziwe ezitholakala kulesi sitshalo, kufaka phakathi i-terpenes namanye ama-cannabinoids.

Kodwa-ke, esimweni se-CBD ebanzi, yonke i-THC iyasuswa.

Ngenxa yalokhu, imikhiqizo ebanzi ye-CBD mancane amathuba okuthi iqukethe i-THC kunemikhiqizo egcwele ye-CBD.

Lolu hlobo lwe-CBD alutholakali kabanzi. Kuvame ukuthengiswa njengamafutha.

CBD ukuhlukanisa

Ukuhlukaniswa kwe-CBD yi-CBD emsulwa. Ayinazo izakhi ezengeziwe ezivela esitshalweni ekhishwe kuso.

Ukuhlukaniswa kwe-CBD kuvame ukuvela ezitshalweni ze-hemp. Ukuhlukaniswa kwe-CBD ese-Hemp akufanele kube ne-THC.

Lolu hlobo lwe-CBD kwesinye isikhathi luthengiswa njenge-crystalline powder noma i- “slab” esincane, esiqinile esingahlephuka sidliwe. Iphinde itholakale njengamafutha noma i-tincture.

Yimalini iTHC okufanele ibe khona ukuze ubhalise ekuhlolweni kwezidakamizwa?

Isikrini sokuhlolwa kwezidakamizwa se-THC noma enye yama-metabolites asemqoka, i-THC-COOH.

Ngokuya nge-Mayo Clinic Proceedings kusukela ngonyaka ka-2017, amanani okusika wokuhlolwa kwezidakamizwa emsebenzini asungulwe ukugwema ukuthi kungenzeka ukuthi ukulandelela inani le-THC noma i-THC-COOH kungadala isivivinyo esihle.

Ngamanye amagama, ukuphumelela ukuhlolwa kwezidakamizwa akusho ukuthi ayikho i-THC noma i-THC-COOH ekhona kusistimu yakho.

Esikhundleni salokho, ukuhlolwa kwezidakamizwa okungekuhle kukhombisa ukuthi inani le-THC noma i-THC-COOH lingaphansi kwenani elisikiwe.

Izindlela ezahlukahlukene zokuhlola zinamanani ahlukile okusika namawindi wokuthola, njengoba kubhalwe ngezansi.

Umchamo

Ukuvivinywa kwe-cannabis kuvamile, ikakhulukazi emsebenzini.

Emchameni, i-THC-COOH kumele ibe khona lapho kuhlushwa (ng / mL) ukuqala isivivinyo esihle. (I-nanogram icishe ibe isigidigidi segramu.)

Amawindi wokuthola ayahlukahluka kakhulu ngokuya ngomthamo nobuningi bokusetshenziswa. Ngokuvamile, ama-metabolites we-THC ayatholakala emchameni cishe izinsuku ezintathu kuya kwezingu-15 ngemuva kokusetshenziswa.

Kepha ukusetshenziswa kwe-cannabis okunzima, nokuvame kakhulu kungaholela kumawindi wokuthola amade - izinsuku ezingaphezu kwezingu-30, kwezinye izimo.

Igazi

Ukuhlolwa kwegazi akuvamile kakhulu kunezivivinyo zomchamo zokuhlolwa kwezidakamizwa, ngakho-ke akunakwenzeka ukuthi zisetshenziselwe ukuhlolwa kwendawo yokusebenza. Lokhu kungenxa yokuthi iTHC isuswa masinyane egazini.

Itholakala kuphela nge-plasma kuze kufinyelele emahoreni amahlanu, noma kunjalo i-THC metabolites iyatholakala kuze kube yizinsuku eziyisikhombisa.

Ukuhlolwa kwegazi kuvame ukusetshenziselwa ukukhombisa ukukhubazeka kwamanje, ngokwesibonelo, ezimweni zokushayela uphuzile.

Ezimeni lapho insangu isemthethweni, i-THC yegazi loku-1, 2, noma i-5 ng / mL iphakamisa ukukhubazeka. Ezinye izifundazwe zinezinqubomgomo zokubekezelela zero.

Amathe

Njengamanje, ukuhlolwa kwamathe akuvamile, futhi ayikho imikhawulo esikiwe yokunquma ukuthola i-THC ematheni.

Iqoqo lokushicilelwa ku-Journal of Medical Toxicology liphakamisa inani elisikiwe le-4 ng / mL.

I-THC iyatholakala kuketshezi lomlomo cishe amahora angama-72, kepha ingatholwa isikhathi eside ngokusetshenziswa okungapheli, okunzima.

Izinwele

Ukuhlolwa kwezinwele akuvamile, futhi njengamanje ayikho imingcele esikiwe yokunquma ama-metabolites we-THC ezinweleni.

Ukuqedwa kwezimboni ezizimele kufaka phakathi i-1 picogram nge-milligram (pg / mg) ye-THC-COOH. (I-picogram icishe ibe isigriliyoni esisodwa segremu.)

I-THC metabolites iyabonakala ezinwele kuze kube yizinsuku ezingama-90.

Kungani okunye ukusetshenziswa kwe-CBD kungaholela kumphumela omuhle wokuhlolwa we-THC?

Kunezizathu eziningana zokuthi kungani ukusetshenziswa kwe-CBD kungaholela emiphumeleni yokuhlolwa kwezidakamizwa.

Ukungcola okuphambene

Kukhona ukungcola okungqubuzanayo ngesikhathi senqubo yokukhiqiza ye-CBD, noma ngabe i-THC itholakala ngamanani wokulandelela kuphela.

Ukungcola okunqamulelayo kungenzeka kakhulu kubakhiqizi abalungiselela imikhiqizo equkethe i-CBD kuphela, i-THC kuphela, noma inhlanganisela yakho kokubili.

Kunjalo nasezitolo nasemakhaya. Uma uwoyela we-CBD uzungeze ezinye izinto eziqukethe i-THC, ukungcoliswa okuphambene nakho kungenzeka njalo.

Ukuvezwa okwesibili kwe-THC

Yize kungeke kwenzeke ukuthi uthole imiphumela emihle yokuhlolwa kwezidakamizwa ngemuva kokuvezwa intuthu kagwayi kagwayi, kungenzeka.

Olunye ucwaningo luveza ukuthi i-THC oyiphuzayo ngentuthu kagwayi, incike ebuningini bensangu, kanye nosayizi nendawo yokungenisa umoya.

Ukubhalwa okungekho emthethweni komkhiqizo

Imikhiqizo ye-CBD ayilawulwa ngokungaguquguquki, okusho ukuthi ngokujwayelekile akekho umuntu wesithathu ohlola ukwakheka kwayo uqobo.

Ovela eNetherlands uhlolisise ukunemba kwamalebula ahlinzekwe kwimikhiqizo engu-84 ye-CBD kuphela ethengwe ku-inthanethi. Abaphenyi bathole iTHC kwimikhiqizo engu-18 ehlolwe.

Lokhu kusikisela ukuthi ukubhala amagama ngokungekho emthethweni kuvamile embonini, yize kufanele kwenziwe ucwaningo oluningi ukuqinisekisa ukuthi lokhu kuyiqiniso nangemikhiqizo yaseMelika ye-CBD.

Ngabe i-CBD ingaphenduka i-THC emzimbeni?

Ezimweni ezine-asidi, i-CBD ingaphenduka i-THC.

Eminye imithombo icabanga ukuthi lokhu kuguqulwa kwamakhemikhali kwenzeka nasesiswini somuntu, indawo ene-asidi.

Ngokuyinhloko, kuphethwe ukuthi uketshezi lwesisu olulingisiwe lungaguqula i-CBD ibe yiTHC.

Kodwa-ke, kuphethwe ukuthi izimo ze-in vitro azimele izimo zangempela esiswini somuntu, lapho uguquko olufanayo lubonakala lungenzeki.

Abaphenyi ekubuyekezweni kuka-2017 baphinde baveza ukuthi phakathi kwezifundo zokwelashwa ezinokwethenjelwa ezitholakalayo, akekho owabike imiphumela emibi ye-CBD efana naleyo ehambisana ne-THC.

Ungaqiniseka kanjani ukuthi umkhiqizo we-CBD awunayo i-THC?

Eminye imikhiqizo ye-CBD ingahle iphephe kuneminye. Uma ucabanga ukusebenzisa i-CBD, kubalulekile ukuthi uthathe isikhathi sakho ukuhlola imikhiqizo etholakalayo.

Funda imininingwane yomkhiqizo

Thola ukuthi ngabe umkhiqizo uvela ku-hemp noma insangu. Okulandelayo, thola ukuthi ngabe i-CBD igcwele i-spectrum, i-wide-spectrum, noma i-CBD emsulwa.

Khumbula ukuthi imikhiqizo ye-CBD evela kunsangu, kanye nemikhiqizo egcwele ye-CBD etholakala ku-hemp, kungenzeka ukuthi iqukathe i-THC.

Lolu lwazi kufanele kube lula ukuluthola. Uma ingekho encazelweni yomkhiqizo, kungaba uphawu lomkhiqizi ongathembekile.

Khetha imikhiqizo ebala inani le-CBD

Kungumqondo omuhle ukuthola ukugxila kwe-CBD ngomthamo ngamunye.

Khumbula ukuthi kungahluka ngokuya ngokuthi umkhiqizo ungowoyela, i-tincture, uyadliwa, njalonjalo.

Ezimweni eziningi, imikhiqizo ye-CBD egxile kakhulu ibiza kakhulu, noma ingahle ibonakale ilingana noma incane kuneminye imikhiqizo.

Uma kungenzeka, qala ngomkhiqizo wedosi ephansi.

Thola ukuthi imikhiqizo ye-hemp eyenziwe nge-hemp ivela kuphi

Ikhwalithi ye-Hemp iyehluka ngesimo. Izifundazwe ezinedumela elihle, njengeColorado ne-Oregon, zinezimboni ze-hemp ezinde nemihlahlandlela yokuhlola eqinile. Uma imininingwane nge-hemp ingatholakali encazelweni yomkhiqizo, xhumana nomthengisi.

Yenza ucwaningo lwakho

Lapho uhlola umkhiqizo, kufanele ubheke imigomo ethile, efana nale:

• Okuphilayo okuqinisekiswe yi-USDA
• CO₂-kukhishiwe
• i-solvent-free
• decarboxylated
• i-pesticide- noma i-herbicide
• akukho izithasiselo
• azikho izinto zokuvikela
• i-solvent-free
• kuhlolwe ilebhu

Kodwa-ke, ezimweni eziningi kuzoba nzima ukufakazela ukuthi lezi zimangalo ziyiqiniso. Indlela enhle ukubheka noma imiphi imiphumela yokuhlola ilebhu etholakalayo ehambisana nomkhiqizi onikiwe.

Gwema imikhiqizo eyenza izimangalo ezihlobene nempilo

I-Epidiolex, umuthi wesithuthwane, ukuphela komkhiqizo osuselwa ku-CBD onemvume ye-FDA. I-Epidiolex itholakala kuphela ngemithi kadokotela.

Eminye imikhiqizo ye-CBD ayikaze ihlolwe i-FDA ukuhlola ukuphepha nokusebenza kwayo ekwelapheni izinkinga ezithile zempilo, njengokukhathazeka noma ikhanda.

Ngakho-ke, abathengisi abavunyelwe ukwenza izimangalo ezihlobene nempilo nge-CBD. Labo abakwenzayo bephula umthetho.

Ngakho-ke i-CBD emsulwa ngeke ibhalise ekuhlolweni okujwayelekile kwezidakamizwa?

Ukuhlolwa kwezidakamizwa ezijwayelekile akuhlolisisi i-CBD. Esikhundleni salokho, bathola i-THC noma enye yama-metabolites ayo.

Umuntu o-oda ukuhlolwa kwezidakamizwa angacela ukuthi i-CBD ingezwe ohlwini lwezinto ezihlolelwayo. Kodwa-ke, lokhu akunakwenzeka, ikakhulukazi emazweni lapho i-CBD isemthethweni khona.

Okubalulekile

I-CBD akufanele ivele ekuhlolweni okuvamile kwezidakamizwa.

Kodwa-ke, khumbula ukuthi imboni ayilawulwa ngokungaguquguquki, futhi kunzima ukwazi ukuthi uthola ini uma uthenga umkhiqizo we-CBD.

Uma ufuna ukugwema i-THC, qiniseka ukuthi uthenga i-CBD yehlukanisa nomthombo othembekile.

Ingabe i-CBD isemthethweni? Imikhiqizo ye-CBD eyenziwe nge-Hemp (engaphansi kwamaphesenti angu-0,3 iTHC) isemthethweni ezingeni likahulumeni, kepha namanje ayikho emthethweni ngaphansi kweminye imithetho yezwe. Imikhiqizo ye-CBD etholakala ngensangu ayikho emthethweni ezingeni likahulumeni, kodwa isemthethweni ngaphansi kweminye imithetho yezwe.Hlola imithetho yesifundazwe sakho naleyo yanoma iyiphi indawo ohamba kuyo. Khumbula ukuthi imikhiqizo ye-CBD engabhalisiwe ayivunyelwe yi-FDA, futhi ingabhalwa ngokunganembile.