I-Entyvio (vedolizumab)

-Delile

• Kuyini i-Entyvio?
• Ukusebenza ngempumelelo
• I-Entyvio ejwayelekile
• Imiphumela emibi ye-Entyvio
• Imiphumela emibi ejwayelekile
• Imiphumela emibi kakhulu
• Imininingwane yomphumela oseceleni
• PML
• Ukulahleka kwezinwele
• Ukuzuza kwesisindo
• I-Entyvio isebenzisa
• I-Entyvio ye-ulcerative colitis
• Ukuphumelela ekwelapheni i-ulcerative colitis
• I-Entyvio yesifo sikaCrohn
• Ukuphumelela ekwelapheni isifo sikaCrohn
• I-Entyvio yezingane
• Isilinganiso se-Entyvio
• Isheduli yokufaka i-Entyvio
• Kuthiwani uma ngiphuthelwa umthamo?
• Ngabe kuzodingeka ngisebenzise lesi sidakamizwa isikhathi eside?
• Ukugoma
• Ezinye izindlela ze-Entyvio
• I-Entyvio vs. Remicade
• Sebenzisa
• Amafomu ezidakamizwa
• Imiphumela emibi kanye nezingozi
• Ukusebenza ngempumelelo
• Izindleko
• I-Entyvio vs. Humira
• Isebenzisa
• Amafomu ezidakamizwa
• Imiphumela emibi kanye nezingozi
• Ukusebenza ngempumelelo
• Izindleko
• I-Entyvio notshwala
• Ukusebenzisana kwe-Entyvio
• I-Entyvio neminye imithi
• Izidakamizwa ezingasebenzisana ne-Entyvio
• Imithi yokugoma ye-Entyvio futhi ebukhoma
• Ungayilungiselela kanjani ukumnika i-Entyvio
• Ngaphambi kokuqokwa kwakho
• Yini ongayilindela
• I-Entyvio isebenza kanjani
• I-Entyvio nokukhulelwa
• I-Entyvio nokuncelisa
• Imibuzo ejwayelekile mayelana ne-Entyvio
• Ingabe i-Entyvio iyi-biologic?
• U-Entyvio uthatha isikhathi esingakanani ukusebenza?
• Ungathatha i-Entyvio uma uzohlinzwa?
• Izexwayiso ze-Entyvio

Kuyini i-Entyvio?

I-Entyvio (i-vedolizumab) umuthi kadokotela onegama lomuthi. Ngokuvamile kusetshenziselwa ukwelapha i-ulcerative colitis (UC) noma isifo sikaCrohn ngokulinganisela kubantu abangenakho ukuthuthuka okwanele kweminye imithi.

I-Entyvio yisidakamizwa se-biologic esesigabeni semithi ebizwa ngokuthi i-integrin receptor antagonists. Kuza njengesisombululo esinikezwa ukufakwa emthanjeni (IV).

Ukusebenza ngempumelelo

Ukuze uthole ulwazi mayelana nokusebenza kwe-Entyvio, bheka isigaba se- "Entyvio uses" ngezansi.

I-Entyvio ejwayelekile

I-Entyvio iqukethe i-vedolizumab yomuthi. I-Vedolizumab ayitholakali njengomuthi ojwayelekile. Itholakala kuphela njenge-Entyvio.

Imiphumela emibi ye-Entyvio

I-Entyvio ingadala imiphumela emibi noma emibi. Uhlu olulandelayo luqukethe eminye yemiphumela emibi engase ivele ngenkathi uthatha i-Entyvio. Lolu hlu alufaki yonke imiphumela emibi engaba khona.

Ngeminye imininingwane ngemiphumela engemihle ye-Entyvio, noma amathiphu wokuthi ungabhekana kanjani nemiphumela emibi ekhathazayo, khuluma nodokotela wakho noma usokhemisi.

Imiphumela emibi ejwayelekile

Imiphumela emibi ejwayelekile ye-Entyvio ifaka:

• ikhala eligijimayo
• Umphimbo obuhlungu
• izifo zokuphefumula ezifana ne-bronchitis noma i-sinus infection
• ikhanda
• ubuhlungu obuhlangene
• isicanucanu
• imfiva
• ukukhathala
• ukukhwehlela
• umkhuhlane
• ukuhlungu obusemhlane
• ukuqubuka noma isikhumba esilumayo

Imiphumela emibi kakhulu

Shayela udokotela wakho ngokushesha uma unemiphumela emibi kakhulu. Shayela u-911 uma izimpawu zakho zizizwa zisongela impilo noma uma ucabanga ukuthi unezimo eziphuthumayo zezokwelapha. Imiphumela emibi kanye nezimpawu zayo zingafaka okulandelayo:

• Ukusabela okweqile. Abanye abantu bangaba nokungezwani komzimba uma kunikezwa i-Entyvio. Lezi zivame ukungabi bucayi, kepha zingaba nzima kwezinye izimo. Ukuphathwa kwe-Entyvio kuzodingeka kumiswe uma kwenzeka ukusabela okunzima. Izimpawu zokuphendula okweqile zingafaka:
  • inkinga yokuphefumula
  • isikhumba esilumayo
  • ukuqhuma
  • ukuqubuka
• Ukulimala kwesibindi. Abanye abantu abathola i-Entyvio bangathola ukulimala kwesibindi. Uma uthuthukisa izimpawu zokulimala kwesibindi, udokotela wakho angamisa ukwelashwa kwakho nge-Entyvio. Izimpawu zokulimala kwesibindi zingafaka:
  • ukuphuzi kwesikhumba sakho noma okumhlophe kwamehlo akho
  • ukukhathala
  • ubuhlungu besisu
• Umdlavuza. Ngesikhathi sokucwaninga nge-Entyvio, cishe amaphesenti angu-0.4 alabo abathola i-Entyvio baba nomdlavuza uma kuqhathaniswa namaphesenti angama-0.3 athola i-placebo. Ukuthi i-Entyvio inyusa ingozi yomdlavuza akucaci.
• Izifo. Abantu abathatha i-Entyvio banengozi eyengeziwe yokutheleleka, njengomkhuhlane ovamile noma umkhuhlane. Ukutheleleka okungathi sína nakho kungenzeka. Lokhu kungafaka isifo sofuba noma ukutheleleka ebuchosheni okubizwa nge-leukoencephalopathy eqhubekayo (bheka ngezansi). Uma uba nokutheleleka okunzima ngenkathi uthatha i-Entyvio, kungadingeka ukuthi uyeke ukuthatha imishanguzo kuze kube yilapho isifo sesilashwa.

Imininingwane yomphumela oseceleni

Ungase uzibuze ukuthi kaningi kangakanani imiphumela emibi ethile eba khona ngalo muthi. Nayi imininingwane ngemiphumela ethile eseceleni engadalwa yilesi sidakamizwa.

PML

I-leukoencephalopathy eqhubekayo ye-multifocal (PML) ukutheleleka okunamandla kwegciwane ebuchosheni. Ngokuvamile kwenzeka kuphela kubantu amasosha omzimba wabo angasebenzi ngokugcwele.

Ngesikhathi sokufunda, i-PML ayenzekanga kunoma ngubani othathe i-Entyvio. Kodwa-ke, kwenzeke kubantu abathola imishanguzo efana ne-Entyvio, efana neTysabri (natalizumab).

Ngenkathi uthatha i-Entyvio, udokotela wakho uzokuqapha ngezimpawu ze-PML. Lezi zimpawu zingafaka:

• ubuthakathaka ohlangothini olulodwa lomzimba wakho
• izinkinga zokubona
• ubulukhuni
• izinkinga zememori
• ukudideka

Uma unemibuzo noma ukukhathazeka ngale mphumela ongaba khona, khuluma nodokotela wakho noma usokhemisi.

Ukulahleka kwezinwele

Ukulahleka kwezinwele akuyona imphumela eseceleni eyenzekile ezifundweni ze-Entyvio. Kodwa-ke, abanye abantu baye balahlekelwa izinwele ngenkathi bethatha i-Entyvio. Akucaci ukuthi i-Entyvio iyimbangela yokulahleka kwezinwele. Uma unemibuzo noma ukukhathazeka ngale mphumela ongaba khona, khuluma nodokotela wakho noma usokhemisi.

Ukuzuza kwesisindo

Ukuzuza kwesisindo akuwona umphumela ohlangothini owenzekile ezifundweni ze-Entyvio. Kodwa-ke, abanye abantu abathatha i-Entyvio bathi bayakhuluphala. Ukuzuza isisindo kungaba ngumphumela wokuphulukiswa emathunjini, ikakhulukazi kulabo abaphelelwe yisisindo ngenxa yokuqhamuka kwezimpawu zesimo eselashwa. Uma unemibuzo noma ukukhathazeka mayelana nokuzuza kwesisindo ngesikhathi sokwelashwa kwakho, khuluma nodokotela wakho noma usokhemisi.

I-Entyvio isebenzisa

Ukuphathwa Kwezokudla Nezidakamizwa (i-FDA) kuvumela imishanguzo kadokotela efana ne-Entyvio ukwelapha izimo ezithile.

I-Entyvio igunyazwe yi-FDA ukwelapha izimo ezimbili: i-ulcerative colitis (UC) nesifo sikaCrohn.

I-Entyvio ye-ulcerative colitis

I-Entyvio isetshenziselwa ukuthuthukisa izimpawu futhi ibangele ukuxolelwa kwezimpawu kubantu abane-UC enesilinganiso esibi Inqunyelwe abantu abangenakho ukuthuthuka okwanele ngeminye imithi, noma abangakwazi ukuthatha eminye imithi.

Ukuphumelela ekwelapheni i-ulcerative colitis

Ku-UC, izifundo zemitholampilo zithole ukuthi i-Entyvio iphumelele ekwenziweni kokuxolelwa kwezimpawu.

Imihlahlandlela evela ku-American Gastroenterological Association incoma ukusebenzisa i-ejenti ye-biologic efana ne-vedolizumab (umuthi osebenzayo ku-Entyvio) ekunciphiseni nasekugcineni ukuxolelwa kubantu abadala abane-UC elinganiselayo neqinile.

I-Entyvio yesifo sikaCrohn

I-Entyvio isetshenziselwa ukuthuthukisa izimpawu futhi ibangele ukuthethelelwa kwezimpawu kubantu abanesifo sikaCrohn's ngokulingene kuya kokubi. Inqunyelwe abantu abangenakho ukuthuthuka okwanele ngeminye imithi, noma abangakwazi ukuthatha eminye imithi.

Ukuphumelela ekwelapheni isifo sikaCrohn

Ngesifo sikaCrohn, izifundo zomtholampilo zithole i-Entyvio ukuthi iphumelele ekuletheni ukuxolelwa kwezimpawu.

Imihlahlandlela evela e-American College of Gastroenterology incoma i-vedolizumab (umuthi osebenzayo e-Entyvio) wokunciphisa ukuxolelwa nokuphulukiswa kwamathumbu kubantu abadala abane-Crohn's disease esebenzayo.

I-Entyvio yezingane

I-Entyvio ayivunyelwe yi-FDA ukuthi isetshenziswe ezinganeni. Kodwa-ke, abanye odokotela bangasebenzisa i-Entyvio off-label yokwelapha i-UC noma isifo sikaCrohn ezinganeni.

Ucwaningo oluthile lwathola ukuthi i-Entyvio ibangele ukuthethelelwa kwezimpawu kumaphesenti angama-76 ezingane ezine-UC, kanye namaphesenti angama-42 ezingane ezine-Crohn's disease.

Isilinganiso se-Entyvio

Imininingwane elandelayo ichaza imithamo esetshenziswa kakhulu noma enconywayo. Kodwa-ke, qiniseka ukuthatha isilinganiso udokotela wakho akubekela sona. Udokotela wakho uzonquma isilinganiso esihle kakhulu ukuhlangabezana nezidingo zakho.

Isheduli yokufaka i-Entyvio

I-Entyvio ilawulwa ukufakwa emthanjeni (IV), okusho ukuthi ufakwa kancane kancane emthanjeni wakho. Ukufakwa ukumnika ukuphathwa okulawulwayo kwemithi egazini lakho isikhathi esithile.

Ekwelashweni ngakunye, kunikezwa umthamo ongu-300 mg esikhathini esiyimizuzu engama-30. Ukwelashwa kuqalwa ngokuvumelana nalesi simiso:

• Isonto 0 (isonto lokuqala): umthamo wokuqala
• Isonto 1: awukho umthamo
• Isonto 2: umthamo wesibili
• Isonto 6: umthamo wesithathu

Ngemuva kwalesi sikhathi sokuqala samasonto ayisithupha, okuthiwa yi-induction, kusetshenziswa uhlelo lokufakwa kwesondlo. Ngesikhathi sokufakwa kwesondlo, i-Entyvio inikezwa njalo emavikini ayisishiyagalombili.

Kuthiwani uma ngiphuthelwa umthamo?

Le mithi izonikezwa udokotela wakho. Uma uphuthelwa ukuqokwa kwakho ukuthola umthamo wakho, shayela ihhovisi likadokotela wakho khona manjalo ukuhlela kabusha ukwelashwa kwakho.

Ngabe kuzodingeka ngisebenzise lesi sidakamizwa isikhathi eside?

Yebo, i-Entyvio idinga ukusetshenziselwa ukwelashwa kwesikhathi eside.

Ukugoma

Ngaphambi kokuqala i-Entyvio, kuzodingeka ube usesikhathini ngemigomo yokugoma enconyiwe. Khuluma nodokotela wakho mayelana nokuthola noma yimiphi imithi yokugoma oyidingayo ngaphambi kokuqala ukwelashwa nge-Entyvio.

Ezinye izindlela ze-Entyvio

Kunemithi eminingi ehlukene esetshenziselwa ukwelapha i-ulcerative colitis (UC) nesifo sikaCrohn. Lezi ezinye izidakamizwa zingabhekwa njengezinye izindlela kune-Entyvio.

I-Entyvio iyisidakamizwa se-biologic esivame ukusetshenziselwa ukwelapha isifo se-UC neCrohn lapho eminye imithi ingazinciphisi izimpawu ngokwanele, noma uma ibangela imiphumela emibi ekhathazayo. Izibonelo zeminye imithi ye-biologic esetshenziselwa ukwelapha i-UC noma isifo sikaCrohn zifaka:

• natalizumab (Tysabri), umphikisi we-integrin receptor
• ustekinumab (Stelara), umphikisi we-interleukin IL-12 no-IL-23
• i-tofacitinib (Xeljanz), iJanus kinase inhibitor
• isimila necrosis factor (TNF) -alpha inhibitors njenge:
  • i-adalimumab (Humira)
  • isitifiketi (Cimzia)
  • golimumab (Simponi)
  • infliximab (i-Remicade)

I-Entyvio vs. Remicade

I-Entyvio ne-Remicade (infliximab) yomibili iyimithi yokwenziwa kwe-biologic, kodwa ikwezigaba ezahlukahlukene zezidakamizwa. I-Entyvio ingeyesigaba sezidakamizwa ezibizwa ngokuthi yi-integrin receptor antagonists. I-Remicade ingeyesigaba semithi ebizwa nge-tumor necrosis factor (TNF) -alpha inhibitors.

Sebenzisa

I-Entyvio ne-Remicade zombili zivunyelwe i-FDA ekwelapheni isifo se-UC nesikaCrohn. I-Remicade nayo ivunyelwe ukwelapha ezinye izimo, kufaka phakathi:

• isifo samathambo
• ukhwekhwe
• isifo samathambo psoriatic
• i-ankylosing spondylitis

Amafomu ezidakamizwa

Kokubili i-Entyvio ne-Remicade kuyatholakala njengezisombululo zokufakwa ngaphakathi kwe-intravenous (IV). Kuphathwa futhi kumashejuli afanayo. Ngemuva kwemithamo yokuqala emithathu, le mithi inikezwa njalo emavikini ayisishiyagalombili.

Imiphumela emibi kanye nezingozi

I-Entyvio ne-Remicade zinemiphumela efanayo efanayo, kanti eminye yehlukile. Ngezansi kunezibonelo zale miphumela emibi.

I-Remicade inezixwayiso zesibhakela ezivela ku-FDA.Isexwayiso esibhokisi yisixwayiso esiqine kakhulu esidingwa yi-FDA. Kwazisa odokotela neziguli ngemiphumela yezidakamizwa engaba yingozi.

Ukusebenza ngempumelelo

Kokubili i-Entyvio ne-Remicade kusetshenziselwa ukwelapha isifo se-UC nesikaCrohn. Kepha i-Entyvio imane isetshenziselwe ukwelapha isifo se-UC kanye neCrohn kubantu abangenakho ukuthuthuka okwanele ngeminye imithi efana neRemicade.

Ukusebenza kwale mithi akukaze kuqhathaniswe ngqo ezifundweni zomtholampilo. Kodwa-ke, abanye abacwaningi ngo-2014 nango-2016 baqhathanisa imiphumela evela ezifundweni ezahlukahlukene ngale mithi.

Imihlahlandlela evela ku-American Gastroenterological Association incoma ukusebenzisa i-ejenti ye-biologic efana ne-vedolizumab (umuthi osebenzayo ku-Entyvio) noma i-infliximab (umuthi osebenzayo eRemicade) wokunciphisa nokugcina ukuxolelwa kubantu abadala abane-UC elinganiselayo kuya enzima.

Imihlahlandlela evela e-American College of Gastroenterology incoma kokubili i-vedolizumab (umuthi osebenzayo ku-Entyvio) ne-infliximab (umuthi osebenzayo eRemicade) wokwelapha abantu abadala abane-Crohn's disease esezingeni eliphakathi nendawo.

Izindleko

Izindleko ze-Entyvio noma i-Remicade zingahluka ngokuya ngohlelo lwakho lokwelashwa. Intengo yangempela ozoyikhokhela i-Entyvio noma i-Remicade incike ohlelweni lwakho lomshuwalense, indawo okuyo nasekhemisi oyisebenzisayo. Ukuze uthole ukuthi umuthi ngamunye ungabiza malini endaweni yakho, vakashela i-GoodRx.com.

I-Entyvio vs. Humira

I-Entyvio ne-Humira (i-adalimumab) yomibili imishanguzo ye-biologic, kodwa ikwezigaba ezahlukahlukene zezidakamizwa. I-Entyvio ingeyesigaba sezidakamizwa ezibizwa ngokuthi yi-integrin receptor antagonists. I-Humira ingeyesigaba semithi ebizwa nge-tumor necrosis factor (TNF) -alpha inhibitors.

Isebenzisa

I-Entyvio neHumira bobabili bavunyelwe yi-FDA ekwelapheni i-ulcerative colitis (UC) nesifo sikaCrohn. I-Humira nayo ivunyelwe ukwelapha ezinye izimo, kufaka phakathi:

• isifo samathambo
• ukhwekhwe
• isifo samathambo psoriatic
• i-ankylosing spondylitis
• uveitis

Amafomu ezidakamizwa

I-Entyvio iza njengesisombululo sokufakwa ngaphakathi emithanjeni okunikezwa ehhovisi likadokotela. Ngemuva kwemithamo emithathu yokuqala, i-Entyvio inikezwa kanye njalo emavikini ayisishiyagalombili.

I-Humira iza njengomjovo ongaphansi. Lo ngumjovo onikezwa ngaphansi kwesikhumba. I-Humira ingazilawula ngokwakho. Ngemuva kwamasonto amane okuqala, isetshenziswa njalo ngesonto.

Imiphumela emibi kanye nezingozi

I-Entyvio neHumira zinemiphumela emibi efanayo, kanti eminye yehlukile. Ngezansi kunezibonelo zale miphumela emibi.

UHumira unesixwayiso esibhokisi esivela ku-FDA. Lesi yisixwayiso esiqine kakhulu esidingwa yi-FDA. Isexwayiso sebhokisi sazisa odokotela neziguli ngemiphumela yezidakamizwa engaba yingozi.

Ukusebenza ngempumelelo

I-Entyvio neHumira zisetshenziselwa ukwelapha isifo i-UC kanye neCrohn's. Kodwa-ke, i-Entyvio ijwayele ukusetshenziselwa abantu abangenakho ukuthuthuka okwanele besebenzisa eminye imithi, efana neHumira.

Ukusebenza kwale mithi akukaze kuqhathaniswe ngqo ezifundweni zomtholampilo. Kepha ukuhlaziywa okuthile okusuka ku-2014 no-2016 kunikela ngeminye imininingwane yokuqhathanisa.

Izindleko

Izindleko ze-Entyvio noma i-Humira zingahluka ngokuya ngohlelo lwakho lokwelashwa. Intengo yangempela ozoyikhokhela i-Entyvio noma i-Humira incike ohlelweni lwakho lomshuwalense, indawo okuyo nasekhemisi oyisebenzisayo. Ukuze uthole ukuthi umuthi ngamunye ungabiza malini endaweni yakho, vakashela i-GoodRx.com.

Ukusebenza kwale mithi yokwelapha isifo sikaCrohn akukaze kuqhathaniswe ngqo ezifundweni zokwelashwa. Kodwa-ke, ukuqhathanisa okungaqondile kutholile ukuthi i-Entyvio neCimzia zisebenza ngokulinganayo ngokuxolelwa kwezimpawu kubantu abangakaze basebenzise imishanguzo ye-biologic phambilini.

I-Entyvio notshwala

I-Entyvio ayihlangani notshwala. Kodwa-ke, ukuphuza utshwala kungadala eminye imiphumela emibi ye-Entyvio, enjenge:

• isicanucanu
• ikhanda
• ikhala eligijimayo

Futhi, ukuphuza ngokweqile utshwala kungakhuphula ubungozi bokulimala kwesibindi kusuka ku-Entyvio.

Kubalulekile futhi ukuqaphela ukuthi ukusetshenziswa kotshwala kungazenza zibe zimbi kakhulu ezinye izimpawu zesifo sezilonda (UC) noma isifo sikaCrohn. Lezi zimpawu zifaka:

• isicanucanu
• ukuhlanza
• ukuphuma kwesisu noma kwamathumbu
• isifo sohudo

Ukusebenzisana kwe-Entyvio

I-Entyvio ingaxhumana neminye imithi eminingana.

Ukuxhumana okuhlukile kungadala imiphumela ehlukile. Isibonelo, ezinye zingaphazamisa ukuthi usebenza kanjani umuthi, kanti ezinye zingadala imiphumela emibi eyengeziwe.

I-Entyvio neminye imithi

Ngezansi uhlu lwemithi engasebenzisana ne-Entyvio. Lolu hlu aluqukethe yonke imishanguzo engasebenzisana ne-Entyvio.

Ngaphambi kokuthatha i-Entyvio, qiniseka ukuthi utshela udokotela kanye nosokhemisi mayelana nayo yonke imishanguzo kadokotela, i-counter-counter, nezinye izidakamizwa ozithathayo. Batshele futhi nganoma yimaphi amavithamini, amakhambi, nezithako ozisebenzisayo. Ukwabelana ngalolu lwazi kungakusiza ugweme ukuhlangana okungenzeka.

Uma unemibuzo mayelana nokuhlangana kwezidakamizwa okungakuthinta, buza udokotela wakho noma usokhemisi.

Izidakamizwa ezingasebenzisana ne-Entyvio

Ngezansi kunezibonelo zemithi engasebenzisana ne-Entyvio. Lolu hlu aluqukethe yonke imishanguzo engasebenzisana ne-Entyvio.

• I-tumor necrosis factor inhibitors. Ukuthatha i-Entyvio nge-tumor necrosis factor inhibitors kungandisa ingozi yokutheleleka. Izibonelo zale mithi zifaka:
  • i-adalimumab (Humira)
  • isitifiketi (Cimzia)
  • golimumab (Simponi)
  • infliximab (i-Remicade)
• INatalizumab (iTysabri). Ukuthatha i-Entyvio nge-natalizumab kungakhuphula ubungozi bokutheleleka okungathi sína kobuchopho okubizwa ngokuthi yi-progressive multifocal leukoencephalopathy (PML).

Imithi yokugoma ye-Entyvio futhi ebukhoma

Eminye imigomo iqukethe amagciwane asebenzayo kodwa abuthakathaka noma amabhaktheriya. Lezi zivame ukubizwa ngokuthi yimithi yokugoma ebukhoma. Uma uthatha i-Entyvio, akufanele uthole imigomo ebukhoma. Lokhu kungakhuphula ubungozi bokuthola ukutheleleka obekuhloselwe ukugwema. Izibonelo zale mithi yokugoma zifaka:

• umuthi wokugomela umkhuhlane wamakhala (i-FluMist)
• imigomo ye-rotavirus (Rotateq, Rotarix)
• isimungumungwane, imvukuzane, irubella (MMR)
• umuthi wokugomela izinkukhu (Varivax)
• umuthi wokugomela i-yellow fever (YF Vax)

Ungayilungiselela kanjani ukumnika i-Entyvio

I-Entyvio inikezwa njenge-infravenous (IV) ukumnika. Lokhu kusho ukuthi idinga ukunikezwa ehhovisi likadokotela wakho, esibhedlela, noma esikhungweni sokumnika.

Ngaphambi kokuqokwa kwakho

Udokotela wakho noma umhlengikazi uzokunikeza imiyalo yakho ethize yokuthi ungakulungiselela kanjani ukumnika, kepha nazi izeluleko ezithile:

• Phuza iziphuzo. Qinisekisa ukuthi uphuza uketshezi oluningi ngosuku noma ezimbili ngaphambi kokuqokwa kwakho kokumnika. Kubantu abaningi, lokhu kufanele kube izingilazi eziyisithupha kuya kweziyisishiyagalombili zamanzi noma uketshezi nsuku zonke. Zama ukugwema ukuphuza kakhulu i-caffeine, engadala uketshezi oketshezi.
• Tshela udokotela wakho. Uma unezimpawu zokutheleleka, njengokukhwehlela noma umkhuhlane, qiniseka ukuthi wazise udokotela wakho. Phinda utshele udokotela wakho uma uthatha ama-antibiotics. Kunoma ikuphi, ungadinga ukuhlela kabusha ukumnika kwakho.
• Shesha ukufika. Ngokumnika kwakho kokuqala, hlela ukufika imizuzu engu-15 kuya kwengu-20 ngaphambi kwesikhathi ukuze uqedele amaphepha, uma kudingeka.
• Woza uzilungiselele. Lokhu kufaka:
• Ukugqoka ngezendlalelo. Abanye abantu bazizwa bebanda ngenkathi bethola ukumnika kwabo.
• Ukuletha isidlo noma isidlo sasemini. Yize ukuminyelwa kungahlali isikhathi eside, ungahle uthande ukudla uma ufakwa ukumnika ngesikhathi sakho sekhefu sasemini.
• Ukuletha ifoni yakho ephathekayo, amahedfoni, noma incwadi uma ufuna ukuzijabulisa ngesikhathi sokufakwa.
• Ukwazi uhlelo lwakho. Uma uneholide elizayo noma ezinye izikhathi ngeke utholakale, isikhathi sakho esibekiwe yisikhathi esihle sokuphothula izinsuku zokumnika esikhathini esizayo.

Yini ongayilindela

• Ngesikhathi sokuqokwa kwakho, uzothola i-IV. Lapho i-IV isifakiwe emthanjeni wakho, ukumnika uqobo kuvame ukuhlala cishe imizuzu engama-30.
• Lapho ukumnika sekuqediwe, ungabuyela emsebenzini noma emisebenzini ejwayelekile yansuku zonke. Abanye abantu banemiphumela emibi elandelayo kulandela ukumnika, njenge:
• ubumnene noma ukulinyazwa endaweni ye-IV
• izimpawu ezibandayo
• ikhanda
• ukukhathala
• isicanucanu
• ubuhlungu obuhlangene
• ukuqubuka

Lezi zimpawu zivame ukuphela kungakapheli usuku noma ezimbili. Uma zingahambi, shayela udokotela wakho. Uma uba nezimpawu zokuphendula okweqile, njengokuhlupheka ukuphefumula noma ukuvuvukala ebusweni, izindebe, noma umlomo, shayela u-911 noma umuntu othile akuyise ekamelweni eliphuthumayo.

I-Entyvio isebenza kanjani

Izimpawu ze-ulcerative colitis (UC) nesifo sikaCrohn zibangelwa ukuvuvukala esiswini. Lokhu kuvuvukala kudalwa ukuhamba kwamaseli athile amhlophe egazi aye emathunjini (emathunjini).

Indlela yokusebenza ye-Entyvio ukuthi ivimba ezinye zezimpawu ezenza la maseli amhlophe egazi angene emathunjini. Lesi senzo singanciphisa ukuvuvukala nezinye izimpawu zesifo se-UC nesikaCrohn.

I-Entyvio nokukhulelwa

Azikho izifundo kubantu eziye zahlola ukuthi ngabe i-Entyvio iphephile yini ukuthi ingasetshenziswa ngesikhathi sokukhulelwa. Izifundo zezilwane azikatholi miphumela emibi, kepha izifundo ezilwaneni azihlali zibikezela ukuthi kuzokwenzekani kubantu.

Uma kunezingozi embungwini, zingaba nkulu kakhulu phakathi kwamathathu wesibili nowesithathu. Ngalesi sikhathi, ingane ingase ivezwe komunye umuthi.

Uma uthatha i-Entyvio futhi ukhulelwe noma ucabanga ngokukhulelwa, khuluma nodokotela wakho. Bangakutshela ngezingozi nezinzuzo zokuqhubeka nokwelashwa kwe-Entyvio noma ukukuyeka.

Uma uthola i-Entyvio ngenkathi ukhulelwe, ungabhalisela ukubhaliswa okuzosiza ukuqoqa imininingwane mayelana nesipiliyoni sakho. Ukubhaliswa kokuvezwa kokukhulelwa kusiza ochwepheshe bezokunakekelwa kwezempilo ukuthi bafunde kabanzi ngokuthi izidakamizwa ezithile zibathinta kanjani abesifazane nokukhulelwa kwabo. Ukuze ubhalise, shayela ku-877-825-3327.

I-Entyvio nokuncelisa

Amanani amancane we-Entyvio akhona obisini lwebele. Kodwa-ke, ucwaningo oluncane alutholanga imiphumela emibi ezinganeni ezinceliswa ibele ngomama abathola i-Entyvio.

Uma uthola i-Entyvio futhi ufuna ukuncelisa ingane yakho ibele, khuluma nodokotela wakho ngezingozi ezingaba khona.

Imibuzo ejwayelekile mayelana ne-Entyvio

Nazi izimpendulo zemibuzo ebuzwa njalo nge-Entyvio.

Ingabe i-Entyvio iyi-biologic?

Yebo, i-Entyvio iyisidakamizwa se-biologic. I-biologics yenziwa ngomthombo wezinto eziphilayo, njengamaseli aphilayo.

U-Entyvio uthatha isikhathi esingakanani ukusebenza?

Ukwelashwa nge-Entyvio kwehlukaniswe izingxenye ezimbili. Imithamo yokuqala emithathu inikezwa ngesikhathi sesigaba sokungeniswa, esihlala amasonto ayisithupha wonke. Ngalesi sigaba, umthamo wesibili unikezwa amasonto amabili ngemuva komthamo wokuqala. Umthamo wesithathu unikezwa amasonto amane ngemuva kwesilinganiso sesibili.

Yize izimpawu zingaqala ukuthuthuka ngokushesha ngemuva kokumnika kokuqala, kungathatha isikhathi esigcwele samaviki ayisithupha ukuthola izimpawu ezilawulwayo.

Isigaba sesondlo silandela isigaba sokungeniswa. Ngesikhathi sesondlo, amanani anikezwa njalo emavikini ayisishiyagalombili ukugcina izimpawu zilawulwa.

Ungathatha i-Entyvio uma uzohlinzwa?

Uma unokuhlinzwa okuhleliwe, kufaka phakathi ukuhlinzwa kwamazinyo, ungadinga ukubambezela noma ukuhlela kabusha ukumnika kwakho kwe-Entyvio.

Izexwayiso ze-Entyvio

Ngaphambi kokuthatha i-Entyvio, khuluma nodokotela wakho nganoma yiziphi izimo zezokwelapha onazo. I-Entyvio ingahle ingakulungeli uma unezimo ezithile zezempilo.

• Kubantu abanezifo: I-Entyvio ingazilimaza izifo. Uma unezimpawu zokutheleleka, njengomkhuhlane noma ukukhwehlela, ungahle ungakwazi ukusebenzisa i-Entyvio kuze kube yilapho ukutheleleka sekuphelile.
• Kubantu abanesifo sesibindi: I-Entyvio ingase ibe nzima kakhulu izinkinga zesibindi kulabo asebavele benesifo sesibindi. Kungadala nokulimala kwesibindi.

Ukuzikhulula:Izindaba Zokwelapha Namuhla wenze yonke imizamo yokuqinisekisa ukuthi lonke ulwazi luyiqiniso, luphelele futhi lusesikhathini. Kodwa-ke, le ndatshana akufanele isetshenziswe njengokungena esikhundleni solwazi nobungoti bochwepheshe bezokunakekelwa kwezempilo onelayisense. Kufanele uhlale uthintana nodokotela wakho noma omunye uchwepheshe wezokunakekelwa kwempilo ngaphambi kokuthatha noma imuphi umuthi. Imininingwane yezidakamizwa equkethwe lapha ingashintsha futhi ayihloselwe ukumboza konke ukusetshenziswa okungaba khona, izinkomba, izixwayiso, izexwayiso, ukuxhumana kwezidakamizwa, ukungezwani komzimba, noma imiphumela emibi. Ukungabikho kwezixwayiso noma olunye ulwazi lomuthi othile awukhombisi ukuthi inhlanganisela yezidakamizwa noma yezidakamizwa iphephile, iyasebenza, noma ilungele zonke iziguli noma konke ukusetshenziswa okuthile.