I-Fexaramine: iyini nokuthi isebenza kanjani

-Delile

• Ingabe le nto inemiphumela emibi?
• Izomakethwa nini?

I-Fexaramine yinto entsha efundwayo ngoba inomphumela omuhle ekunciphiseni isisindo nokwanda kwe-insulin ukuzwela. Izifundo eziningana kumagundane akhuluphele zifakazela ukuthi le nto iheha umzimba ukuthi ushise amanoni futhi ngenxa yalokho iholela ekunciphiseni isisindo, ngokunciphisa isisindo samafutha, ngaphandle kwesidingo soshintsho ekudleni.

Le molekyuli, lapho ifakwa, ilingisa "amasiginali" afanayo akhishwa lapho kudliwa ukudla. Ngakho-ke, ngokukhombisa emzimbeni ukuthi kudliwa isidlo esisha, kwenziwa inqubo ye-thermogenesis, "yokwakha isikhala" samakhalori amasha okufanele afakwe, kepha njengoba okufakwa kungumuthi ongenawo amakhalori, lokhu indlela eholela ekunciphiseni isisindo.

Ngokungafani nezinye izinto ze-agonist ze-receptor efanayo ezazakhiwe phambilini, ukwelashwa nge-fexaramine kuvimbela ukusebenza kwayo emathunjini, okuholela ekwandeni kwama-peptide wamathumbu, okuholela emathunjini anempilo nokuncipha kokuvuvukala okuhlelekile.

Zonke lezi zinto zenza i-fexaramine ikhandidethi elinamandla ekwelapheni ukukhuluphala nezifo ezihambisana nokukhuluphala ngokweqile, kufaka phakathi uhlobo lwesifo sikashukela sohlobo 2 nesifo esinamafutha sesibindi.

Ngaphezu kwalokho, kuphinde kwatholakala ukuthi i-fexaramine ilingisa eminye yemiphumela emihle yemethabolikhi yokuhlinzwa kwe-bariatric, okuyinqubo esebenza kahle kakhulu ekwehliseni isisindo somzimba, ukwenza ngcono impilo yabantu abakhuluphele. Kuzo zombili lezi zimo, ukuzwela kwe-insulin kuyathuthukiswa, amazinga e-glucose anciphisiwe, iphrofayili ye-bile acid iyathuthukiswa, ukuvuvukala kwamathumbu kuyehla futhi, ekugcineni, isisindo somzimba siyehla.

Ucwaningo lwesikhathi esizayo luzosiza ukudalula ukuthi ngabe i-fexaramine izohola ekwelashweni okusha kokukhuluphala.

Ingabe le nto inemiphumela emibi?

I-Fexaramine isacwaningwa futhi, ngakho-ke, akunakwenzeka ukwazi ukuthi ibanga imiphumela emibi yini. Kodwa-ke, ngokungafani neminye amakhambi asetshenziselwa ukwehlisa isisindo, i-fexaramine isebenza ngaphandle kokufakwa egazini, igweme imiphumela ethile emibi edalwa yimithi eminingi yokwehlisa isisindo.

Izomakethwa nini?

Akukaziwa ngokuqinisekile ukuthi umuthi uzongena yini emakethe nokuthi ungamakethwa nini, ngoba usesigabeni sokufunda, kodwa kucatshangwa ukuthi uma unemiphumela emihle, ungaqaliswa cishe ku-1 kuye ku-6 iminyaka.