I-Fish Oil vs. Statins: Yini Egcina Ikholesterol Ephansi?

-Delile

• Izisekelo zikawoyela wezinhlanzi
• Zisebenza kanjani izitatimende
• Okushiwo ucwaningo ngamafutha ezinhlanzi
• Okushiwo ngucwaningo ngama-statins
• Isinqumo
• I-Q & A: Ezinye izidakamizwa ze-cholesterol
• Q:
• A:

Ukubuka konke

I-cholesterol ephezulu ingahle ingabangeli izimpawu njalo, kepha idinga ukwelashwa okufanayo. Uma kukhulunywa ngokulawula i-cholesterol yakho, ama-statins ayinkosi.

Ngabe uwoyela wezinhlanzi angasebenza ngokufanayo ukunciphisa i-cholesterol yakho? Qhubeka ufunde ukuze ufunde ukuthi kunqwabelana kanjani.

Izisekelo zikawoyela wezinhlanzi

Uwoyela wezinhlanzi uqukethe i-omega-3 fatty acids, ebizwa ngezinzuzo ezahlukahlukene zezempilo. Phakathi kwezinye izinto, i-omega-3 fatty acids kuthiwa:

• ukulwa nokuvuvukala
• ukunciphisa umfutho wegazi
• thuthukisa impilo yethambo
• ukukhuthaza isikhumba esinempilo

Yize itholakala ngokwemvelo ezinhlanzini, uwoyela wezinhlanzi uvame ukuthathwa efomini lokwengeza.

Ngo-2012, imikhiqizo esetshenzisiwe equkethe uwoyela wezinhlanzi noma i-omega-3 fatty acids.

Zisebenza kanjani izitatimende

Izitatimende zivimba umzimba ekwenzeni i-cholesterol. Bayisiza futhi ekubuyiseleni kabusha uqweqwe olwakhiwe ezindongeni zemithambo.

Olunye ucwaningo lwesikhathi eside luthole ukuthi amaphesenti ama-27.8 amaMelika angaphezu kweminyaka engama-40 ubudala abesebenzisa ama-statins kusukela ngonyaka we-2013.

Okushiwo ucwaningo ngamafutha ezinhlanzi

Izifundo ngoyili wezinhlanzi zixutshiwe. Izengezo zikawoyela wezinhlanzi ziboshelwe kuhlu olude lwezinzuzo, kufaka phakathi:

• kwehle ingozi yesifo senhliziyo nokushaywa unhlangothi
• amazinga aphansi e-triglycerides, noma amafutha egazini
• impilo yengqondo eyandisiwe
• ukuphathwa kangcono kwesifo sikashukela

Ezinye izifundo, njengalezo eziphawulwe ku-a, zithole ukwehla kwengozi yesifo senhliziyo kubantu abathatha izengezo zamafutha ezinhlanzi. Olunye ucwaningo, njengesilingo esisodwa sango-2013 somtholampilo sabantu abangu-12,000 abanezici eziyingozi yenhliziyo, abatholanga lobo bufakazi.

Ngaphezu kwalokho, yize uwoyela wezinhlanzi wehla ngama-triglycerides, abukho ubufakazi obanele bokuthi yehlisa ingozi yokuhlaselwa yisifo senhliziyo.

Uma kuziwa ekwehliseni i-low-density lipoprotein (LDL), eyaziwa nangokuthi i-cholesterol "embi", ubufakazi abukho nje. Eqinisweni, uwoyela wezinhlanzi anganyusa amazinga e-LDL kwabanye abantu ngokusho kokubuyekezwa kwezincwadi zango-2013.

Okushiwo ngucwaningo ngama-statins

Ngokusho komthetho, izitatimende zikhombisa amandla angenakuphikwa okuvimbela isifo senhliziyo kodwa kufanele zithathwe ngokucophelela.

Izitatimende zinezinzuzo ngaphezu kokunciphisa i-cholesterol yakho. Isibonelo, banezinto ezilwa nokuvuvukala ezingasebenza ukuzinzisa imithambo yegazi, futhi zingasiza ukuvimbela ukuhlaselwa yinhliziyo, ngokusho kweMayo Clinic.

Kungenxa yemiphumela yabo emibi engaba khona, njengobuhlungu bemisipha, ukuthi ngokuvamile ibekwa kuphela kubantu abane-cholesterol ephezulu kanye nengozi yesifo senhliziyo. Abathathwa njengemithi yokuvikela.

Isinqumo

Uma une-cholesterol ephezulu, ukuthatha ama-statins kuyindlela ephumelelayo yokulawula ubungozi bakho. Ukuthatha uwoyela wezinhlanzi kungaba nezinzuzo zako, kepha ukwehlisa i-cholesterol yakho ye-LDL akuyona enye yazo.

Khuluma nodokotela wakho ngezinketho zakho kanye nezinzuzo nezingozi zokwelashwa kwe-statin.

Abantu abaningi bathatha izithako njengezindlela zokuzivikela. Kodwa-ke, indlela engcono kakhulu yokusiza ukuvimbela i-cholesterol ephezulu ngokwenza ukukhetha okunempilo, kufaka phakathi:

• ukuyeka ukubhema
• ukudla ukudla okunempilo okuncane okunamafutha agcwele futhi adluliswayo
• ukuphatha isisindo sakho

I-Q & A: Ezinye izidakamizwa ze-cholesterol

Q:

Yiziphi ezinye izidakamizwa ezingasiza ukwehlisa i-cholesterol yami?

A:

Ngaphandle kwama-statins, ezinye izidakamizwa ezisetshenziselwa ukwehlisa i-cholesterol zifaka:

• i-niacin
• izidakamizwa ezisebenza emathunjini akho
• ama-fibrate
• PCSK9 inhibitors

I-Niacin ivithamini B etholakala ekudleni futhi etholakala kwifomu kadokotela ngamanani aphezulu. I-Niacin yehlisa i-cholesterol ye-LDL (embi) futhi inyuse i-cholesterol ye-HDL (enhle). Izidakamizwa ezisebenza emathunjini akho zisetshenziselwa ukwelapha i-cholesterol ephezulu ngokuvimba ukumuncwa kwe-cholesterol emathunjini akho amancane. Kubandakanya i-cholestyramine, i-colesevelam, i-colestipol, ne-ezetimibe. Ama-fibrate avimbela umzimba wakho ekwenzeni ama-triglycerides, noma amafutha, futhi uphakamise i-cholesterol yakho ye-HDL. Ama-fibrate afaka i-fenofibrate ne-gemfibrozil.

Imithi emisha sha ye-cholesterol evunyelwe yi-FDA yi-PCSK9 inhibitors, efaka i-alirocumab ne-evolocumab. Baphatha ngokuyinhloko iziguli ezinesimo sofuzo esibangela i-hypercholesterolemia.

I-Bempedoic acid yisigaba esisha semithi esenziwayo njengamanje. Izifundo zokuqala zikhombisa isithembiso ekhonweni laso lokwelapha i-cholesterol ephezulu.