I-Levodopa Oral Inhalation
-Delile
- Ngaphambi kokusebenzisa i-levodopa inhalation,
- Ukuphefumula kwe-Levodopa kungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
- Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu noma lezo esigabeni esikhethekile SOKUQAPHA, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
I-Levodopa inhalation isetshenziswa kanye nenhlanganisela ye-levodopa ne-carbidopa (i-Duopa, i-Rytary, i-Sinemet) yokwelapha iziqephu '' '' (izikhathi zobunzima bokuhamba, ukuhamba, nokukhuluma okungenzeka lapho eminye imithi iphela) ku abantu abanesifo sikaParkinson's (PD; ukuphazamiseka kwesistimu yezinzwa okubangela ubunzima ngokunyakaza, ukulawula imisipha, nokulinganisela). Ukuhogela i-Levodopa ngeke kusebenze ukuvikela iziqephu ’’ ’’ kodwa kuzosiza ekulawuleni izimpawu uma isiqephu se- ’’ off ’’ sesiqalile. ILevodopa isekilasini lemithi ebizwa ngama-dopamine agonists. ILevodopa isebenza ngokulingisa isenzo se-dopamine, into yemvelo ebuchosheni entula ezigulini ezine-PD.
I-Levodopa inhalation iza njenge-capsule ezosetshenziswa nge-inhaler yomlomo eyenzelwe ngokukhethekile. Uzosebenzisa i-inhaler ukuphefumula impuphu eyomile equkethwe kumaphilisi. Kuvame ukuhogela lapho kudingeka. Uzodinga ukufaka ngomlomo okuqukethwe kwamaphilisi amabili ngomthamo ogcwele. Ingabe hhayi donsa umthamo ongaphezu kowodwa (amaphilisi ama-2) ngesikhathi "sokuvala" ngasinye. Ingabe hhayi donsa imithamo engaphezu kwama-5 ngosuku olulodwa. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Sebenzisa i-levodopa inhalation njengoba nje kuqondisiwe. Ungayisebenzisi ngaphezulu noma ngaphansi kwayo noma uyisebenzise kaningi kunokuyalelwa ngudokotela wakho.
Ungagwinyi amaphilisi we-levodopa wokuhogela.
Ungavuli iphakethe le-blister elizungeze i-capsule noma ususe i-capsule kuze kube yilapho usulungele ukuyisebenzisa. Uma uvula ngengozi iphakethe le-capsule ongeke ukwazi ukulisebenzisa ngokushesha, lahla lelo philisi. Ungagcini amaphilisi ngaphakathi kwe-inhaler. Lahla i-inhaler lapho wonke amaphilisi akwibhokisi asetshenzisiwe. Sebenzisa i-inhaler entsha eza nokugcwaliswa kwakho kadokotela isikhathi ngasinye.
Sebenzisa kuphela i-inhaler eza nayo ukuhogela i-powder kumaphilisi. Ungalokothi uzame ukuwahogela usebenzisa noma iyiphi enye i-inhaler. Ungalokothi usebenzise i-levodopa inhaler yakho ukuhogela noma imuphi omunye umuthi.
Ngaphambi kokusebenzisa i-levodopa inhalation okokuqala, funda imiyalelo ebhaliwe eza ne-inhaler. Bheka imidwebo ngokucophelela futhi uqiniseke ukuthi uyazibona zonke izingxenye ze-inhaler. Buza udokotela wakho, usokhemisi, noma abanye ochwepheshe bezempilo ukuthi bakukhombise ukuthi ungayisebenzisa kanjani. Prakthiza ukusebenzisa i-inhaler ngenkathi ikubuka.
Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.
Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.
Ngaphambi kokusebenzisa i-levodopa inhalation,
- Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-levodopa, noma imuphi omunye umuthi, noma iziphi izithako ezise-levodopa inhalation. Buza usokhemisi wakho ukuthola uhlu lwezithako.
- Tshela udokotela wakho uma uthatha ama-inhibitors athile e-monoamine oxidase (MAO) afana ne-isocarboxazid (Marplan), phenelzine (Nardil), ne-tranylcypromine (i-Parnate) noma uma uyekile ukuwaphuza emasontweni amabili edlule. Udokotela wakho uzokutshela ukuthi ungasebenzisi i-levodopa inhalation uma uthatha eyodwa noma ngaphezulu yale mithi.
- Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qinisekisa ukusho noma yikuphi kokulandelayo: haloperidol (Haldol); amaphilisi okusansimbi namavithamini aqukethe i-iron; i-isoniazid (Laniazid); i-linezolid (iZyvox); Imithi ye-methylene eluhlaza okwesibhakabhaka yokugula kwengqondo, ukugula kokunyakaza noma isicanucanu; i-metoclopramide (Reglan); eminye imithi yesifo sikaParkinson; i-rasagiline (Azilect); i-risperidone (i-Risperdal); i-safinamide (Xadago); isidambisi; u-selegiline (u-Eldepryl, u-Emsam, uZelapar); amaphilisi okulala; kanye nezithambisi. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo eminingi ingaxhumana ne-levodopa, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho nalawo angaveli kulolu hlu.
- Tshela udokotela wakho uma ngabe uke waba nesifo esithinta ukuphefumula kwakho esifana nesifuba somoya noma isifo samaphaphu esingapheliyo (COPD); i-glaucoma (isimo lapho ukucindezela okwandayo esweni kungaholela ekulahlekelweni kancane kombono); ukuphazamiseka kokulala; noma inkinga yempilo yengqondo.
- tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi usebenzisa i-levodopa inhalation, shayela udokotela wakho.
- kufanele wazi ukuthi i-levodopa inhalation ingakwenza ukozele noma ingakubangela ukuthi ulale ngokuzumayo phakathi nemisebenzi yakho ejwayelekile yansuku zonke ngenkathi usebenzisa i-levodopa inhalation futhi kuze kube unyaka owodwa ngemuva kokwelashwa. Ungahle ungazeli ukozela noma ube nezinye izimpawu zokuxwayisa ngaphambi kokuba ulale ngokuzumayo. Ungashayeli imoto noma usebenzise imishini, usebenze ezindaweni eziphakeme, noma uhlanganyele emisebenzini engaba yingozi uze wazi ukuthi lo muthi ukuthinta kanjani. Uma uvele ulale ngokuzumayo ngenkathi wenza okuthile njengokudla, ukukhuluma, noma ukubukela ithelevishini, noma ukugibela emotweni, noma uma wozela kakhulu, ikakhulukazi ngesikhathi sasemini, shayela udokotela wakho ucingo.
- kufanele wazi ukuthi abanye abantu abasebenzisa imishanguzo efana ne-levodopa inhalation baba nezinkinga zokugembula noma ezinye izifiso ezinamandla noma isimilo ebesibaphoqa noma singavamile kubo, njengokukhuphuka kwezifiso zocansi noma isimilo. Akukho mininingwane eyanele yokutshela ukuthi ngabe abantu baba nezinkinga yini ngenxa yokuthi bathathe umuthi noma ngenxa yezinye izizathu. Shayela udokotela wakho uma unesifiso sokugembula okunzima ukusilawula, unezikhalazo ezinkulu, noma awukwazi ukulawula ukuziphatha kwakho. Tshela amalungu omndeni wakho ngale ngozi ukuze bakwazi ukubiza udokotela noma ngabe awuboni ukuthi ukugembula kwakho noma yiziphi ezinye izifiso ezinamandla noma ukuziphatha okungajwayelekile kube yinkinga.
- kufanele wazi ukuthi i-levodopa inhalation ingadala isiyezi, ikhanda elikhanyayo, isicanucanu, ukujuluka, nokuquleka lapho uvuka ngokushesha okukhulu endaweni yokulala noma yokuhlala. Ukugwema le nkinga, vuka embhedeni noma uvuke endaweni yokuhlala kancane, uphumule izinyawo zakho phansi imizuzu embalwa ngaphambi kokuma.
Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.
Lo muthi uvame ukusetshenziswa lapho kudingeka.
Ukuphefumula kwe-Levodopa kungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
- ukukhwehlela
- ikhala eligijimayo
- isicanucanu
- ukuhlanza
- ubuhlungu bomlomo
- ikhanda
- isiyezi
- shintsha umbala womchamo, umjuluko, isikhwehlela, nezinyembezi
Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu noma lezo esigabeni esikhethekile SOKUQAPHA, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
- umkhuhlane, ukujuluka, imisipha eqinile, nokulahlekelwa ukwazi
- ubuhlungu besifuba noma ukungaphatheki kahle
- ukuphefumula kanzima
- ukunyakaza okusha okungalawuleki okungazelelwe noma okuba kubi kakhulu
- ukusangana (ukubona izinto noma ukuzwa amazwi angekho)
- ukuzwa ukuthi abanye bafuna ukukulimaza
- ubunzima bokulala noma ukulala
- isimilo esinolaka
- ukuphupha ngaphezu kokujwayelekile
- ukudideka
- isimilo esingajwayelekile
- ukuyaluza
Ukuphefumula kwe-Levodopa kungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi usebenzisa lo muthi.
Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).
Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).
Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org
Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.
Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.
Gcina wonke ama-aphoyintimenti nodokotela wakho. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ekuphefumuleni i-levodopa.
Ngaphambi kokwenza noma yiluphi uvivinyo lwelabhoratri, tshela udokotela wakho kanye nabasebenzi belebhuthi ukuthi usebenzisa i-levodopa inhalation.
Ungavumeli omunye umuntu asebenzise imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.
Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.
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