I-Hydroxychloroquine: iyini, yenzelwa ini nemiphumela engemihle

-Delile

• Isetshenziswa kanjani
• 1. I-lupus erythematosus ehlelekile ne-discoid
• 2. I-rheumatoid ne-juvenile arthritis
• 3. Izifo ezithinta izithombe
• 4. Umalaleveva
• Ingabe i-hydroxychloroquine inconyelwa ukwelashwa kokutheleleka kwe-coronavirus?
• Ngubani ongafanele asebenzise
• Imiphumela emibi engaba khona

I-Hydroxychloroquine yisidakamizwa esikhonjiswe ekwelapheni isifo samathambo, i-lupus erythematosus, izimo zesikhumba kanye ne-rheumatic kanye nokwelashwa kwe-malaria.

Le nto esebenzayo ithengiswa ngokuhweba ngaphansi kwegama elithi Plaquinol noma i-Reuquinol, futhi ingathengwa emakhemisi ngentengo engama-65 kuya kuma-85 reais, lapho kwethulwa incwadi kadokotela.

Isetshenziswa kanjani

Umthamo we-hydroxychloroquine uncike enkingeni ezolashwa:

1. I-lupus erythematosus ehlelekile ne-discoid

Umthamo wokuqala we-hydroxychloroquine ngu-400 kuya ku-800 mg ngosuku kanti umthamo wesondlo ungama-200 kuya ku-400 mg ngosuku. Funda ukuthi yini i-lupus erythematosus.

2. I-rheumatoid ne-juvenile arthritis

Umthamo wokuqala ungama-400 kuya ku-600 mg ngosuku kanti umthamo wesondlo ungama-200 kuye ku-400 mg ngosuku. Yazi izimpawu zesifo samathambo nokuthi siphathwa kanjani.

Umthamo wesifo samathambo esingalapheki esentsha akufanele weqe 6.5 mg / kg wesisindo ngosuku, kuze kufike kumthamo omkhulu wansuku zonke ka-400 mg.

3. Izifo ezithinta izithombe

Umthamo onconywayo ngu-400 mg / ngosuku ekuqaleni bese wehliselwa ku-200 mg ngosuku. Okufanelekile, ukwelashwa kufanele kuqale ezinsukwini ezimbalwa ngaphambi kokushiswa yilanga.

4. Umalaleveva

• Ukwelashwa kokucindezela: Kubantu abadala, umthamo onconywayo ungama-400 mg masonto onke kanti ezinganeni kungu-6.5 mg / kg wesisindo somzimba masonto onke.Ukwelashwa kufanele kuqalwe emavikini ama-2 ngaphambi kokuvezwa noma, uma lokhu kungenzeki, kungadingeka ukufaka umthamo wokuqala ka-800 mg kubantu abadala kanye no-12.9 mg / kg ezinganeni, uhlukaniswe ngemithamo emibili, ngamahora ayisithupha okwelashwa. . Ukwelashwa kufanele kuqhubeke amasonto ayi-8 ngemuva kokushiya indawo enendawo.
• Ukwelashwa kwesimo esibucayi: Kubantu abadala, umthamo wokuqala ngu-800 mg olandelwa ngu-400 mg ngemuva kwamahora ayisithupha kuya kwangu-8 no-400 mg nsuku zonke ngezinsuku ezi-2 ezilandelanayo noma, kungenjalo, kungathathwa umthamo owodwa we-800 mg. Ezinganeni, umthamo wokuqala we-12.9 mg / kg kanye nomthamo wesibili ka-6.5 mg / kg kufanele unikezwe amahora ayisithupha ngemuva komthamo wokuqala, umthamo wesithathu ka-6.5 mg / kg amahora angu-18 ngemuva komthamo wesibili nomthamo wesine ka-6.5 mg / kg, amahora angama-24 ngemuva komthamo wesithathu.

Ingabe i-hydroxychloroquine inconyelwa ukwelashwa kokutheleleka kwe-coronavirus?

Ngemuva kokwenza izifundo eziningana zesayensi, kuphethwe ukuthi i-hydroxychloroquine ayinconywa ekwelapheni ukutheleleka nge-coronavirus entsha. Kusanda kukhonjiswa, ezivivinyweni zokwelashwa ezenziwa ezigulini ezine-COVID-19, ukuthi lo muthi ubonakala ungenazinzuzo, ngaphezu kokukhulisa imvamisa yemiphumela emibi kakhulu nokufa, okuholele ekumisweni okwesikhashana kwezilingo zomtholampilo zazenzeka kwamanye amazwe ngomuthi.

Kodwa-ke, imiphumela yalezi zivivinyo iyahlaziywa, ukuze kuqondwe indlela yokwethembeka nokwethembeka kwedatha, kuze kuphinde kuhlolwe ukuphepha komuthi. Funda kabanzi ngemiphumela yezifundo ezenziwe nge-hydroxychloroquine nezinye izidakamizwa ngokulwa ne-coronavirus entsha.

Ngokusho kuka-Anvisa, ukuthengwa kwe-hydroxychloroquine ekhemisi kusavumelekile, kodwa kuphela kubantu abanemibhalo kadokotela yezifo esesizibalile kanye nezinye izimo ebeziyizinkomba zomuthi ngaphambi kobhadane lwe-COVID-19. Ukuzelapha kungaba nemiphumela emibi empilweni, ngakho-ke ngaphambi kokuthatha noma imuphi umuthi kufanele ukhulume nodokotela.

Ngubani ongafanele asebenzise

I-Hydroxychloroquine akufanele isetshenziswe ngabantu abazwela ngokweqile kunoma yiziphi izinto ezikhona kwifomula, ezinama-retinopathies asevele ekhona noma angaphansi kweminyaka engu-6 ubudala.

Imiphumela emibi engaba khona

Imiphumela emibi kakhulu engenzeka ngokusetshenziswa kwalo muthi i-anorexia, ikhanda elibuhlungu, ukuphazamiseka kokubona, ubuhlungu besisu, isicanucanu, isifo sohudo, ukuhlanza, ukuqubuka nokunwaya.