Yazi ukuthi kusho ukuthini i-hormone ye-ACTH ephezulu noma ephansi

-Delile

• Izinguquko ezingenzeka ku-ACTH
• I-ACTH ephezulu
• I-ACTH ephansi
• Izincomo zokuhlolwa

I-adrenocorticotropic hormone, eyaziwa nangokuthi i-corticotrophin kanye ne-ACTH, ikhiqizwa yi-pituitary gland futhi isebenza ikakhulukazi ukuhlola izinkinga ezihlobene nezindlala ze-pituitary ne-adrenal. Ngakho-ke, ukulinganiswa kwe-ACTH kuyasiza ukukhomba izimo ezinjenge-Cushing's syndrome, isifo i-Addison, i-ectopic secretion syndrome, umdlavuza wamaphaphu nowe-thyroid kanye nokwehluleka kwe-adrenal gland, ngokwesibonelo.

Ukuhlolwa kwe-ACTH kuvame ukucelwa ngudokotela kanye nesilinganiso se-cortisol ukuze ubudlelwano phakathi kwala mahomoni amabili buhlolwe, ngoba i-ACTH ivusa ukukhiqizwa kwe-cortisol. Inani elijwayelekile le-ACTH egazini lifinyelela ku-46 pg / mL, engahluka ngokuya nge-laboratory lapho kwenziwa khona ukuhlolwa nesikhathi sokuqoqwa, ngoba amazinga ale hormone ayahlukahluka usuku lonke, futhi ukuqoqwa kuyanconywa ekuseni.

Intengo yesivivinyo se-ACTH yehluka phakathi kuka-R $ 38 no-R $ 50.00 kuya nge-laboratory, noma kunjalo, itholakala yi-SUS.

Izinguquko ezingenzeka ku-ACTH

I-ACTH ifihlwa kancane kancane emini, ngamazinga aphezulu ngo-6 no-8 ekuseni namazinga aphansi ngo-9 ntambama nango-10 ntambama. Ukukhiqizwa kwale hormone kukhula ikakhulukazi ezimeni ezicindezelayo, okukhuthaza ukukhiqizwa kokukhishwa kwe-cortisol, okunesibopho sokulawula ukucindezeleka, ukukhathazeka nokuvuvukala. Funda kabanzi nge-cortisol nokuthi yenzelwe ini.

Izinguquko ezingenzeka ku-ACTH kungaba:

I-ACTH ephezulu

• I-Cushing's syndrome, engaholela ekukhiqizeni okwandayo kwe-ACTH ngendlala ye-pituitary;
• Ukwehluleka okuyinhloko kwe-adrenal;
• I-Adrenogenital syndrome enokwehla kokukhiqizwa kwe-cortisol;
• Ukusetshenziswa kwama-amphetamine, i-insulin, i-levodopa, i-metoclopramide ne-mifepristone.

Ukugxila okuphezulu kakhulu kwe-ACTH egazini kungakhuphula ukuwohloka kwama-lipids, kukhuphule ukugcwala kwamafutha acid kanye ne-glycerol egazini, kukhuthaze uketshezi lwe-insulin futhi kwandise ukukhiqizwa kwehomoni yokukhula, i-GH. Qonda ukuthi yini i-GH nokuthi yenzelwe ini.

I-ACTH ephansi

• I-hypopituitarism;
• Ukungakwazi ukusebenza kwesikhungo kwe-ACTH - i-adrenal yesibili;
• Ukusetshenziswa kwama-corticosteroids, ama-estrogens, i-spironolactone, ama-amphetamine, utshwala, i-lithium, ukukhulelwa, isigaba somjikelezo wokuya esikhathini, ukuvivinya umzimba.

Ukuhlolwa kuyalwa ngudokotela lapho umuntu enezimpawu ezihlobene nokwanda noma ukwehla kwe-cortisol egazini. Izimpawu ezingakhombisa ukuthi i-cortisol ephezulu ikhuluphele ngokweqile, isikhumba esincanyana futhi esintekenteke, izimpawu ezibomvu ezibomvu esiswini, induna, ukwanda kwezinwele zomzimba nezimpawu ezingakhombisa ukuthi i-cortisol ephansi ubuthakathaka, ukukhathala, ukwehla kwesisindo, ukufiphaza isikhumba nokulahlekelwa isifiso sokudla.

Izincomo zokuhlolwa

Ukwenza isivivinyo, kunconywa ukuthi umuntu azile ukudla okungenani amahora ayi-8 noma ngokweseluleko sezokwelapha nokuthi ukuqoqwa kwenziwe ekuseni, okungcono emva kwamahora ama-2 umuntu evukile.

Ngaphezu kwalokho, kubalulekile futhi ukuthi ungenzi ukuzivocavoca umzimba ngosuku lwezivivinyo noma ngayizolo nokunciphisa ukusetshenziswa kwama-carbohydrate njengesinkwa, irayisi, amazambane kanye ne-pasta amahora angama-48 ngaphambi kokuhlolwa, njengoba le hormone isebenza ukulawulwa kwamaprotheni, i-glucose ne-lipid metabolism.