I-Hyperpituitarism

-Delile

• Ukubuka konke
• Izimpawu
• Ziyini izimbangela?
• Izinketho zokwelashwa
• Imithi
• Ukuhlinzwa
• Imisebe
• Kutholakala kanjani?
• Izinkinga nezimo ezihambisanayo
• Umbono

Ukubuka konke

Indlala ye-pituitary iyindlala encane etholakala phansi ebuchosheni bakho. Cishe ilingana nepea. Kuyindlala ye-endocrine. Isimo se-hyperpituitarism senzeka lapho le ndlala iqala ukukhiqiza ngokweqile ama-hormone. Indlala ye-pituitary ikhiqiza ama-hormone alawula eminye yemisebenzi yakho emikhulu yomzimba. Le misebenzi emikhulu yomzimba ifaka phakathi ukukhula, umfutho wegazi, imetabolism, kanye nomsebenzi wezocansi.

I-Hyperpituitarism ingathinta kabi imisebenzi eminingi yomzimba wakho. Lokhu kungafaka:

• umthethonqubo wokukhula
• ukuthomba ezinganeni
• i-pigmentation yesikhumba
• umsebenzi wezocansi
• ukukhiqizwa ubisi lwebele kwabesifazane abancelisayo
• umsebenzi wegilo
• ukukhiqiza kabusha

Izimpawu

Izimpawu ze-hyperpituitarism ziyehluka ngokuya ngesimo esisibangelayo. Sizobheka isimo ngasinye kanye nezimpawu ezihambisana naso ngamunye ngamunye.

Izimpawu ze-Cushing syndrome zingafaka okulandelayo:

• amafutha amaningi emzimbeni
• inani elingajwayelekile lezinwele zobuso kwabesifazane
• ukulinyazwa okulula
• amathambo aphuka kalula noma entekenteke
• izimpawu zokwehliswa esiswini ezinombala onsomi noma opinki

Izimpawu ze-gigantism noma i-acromegaly zingafaka okulandelayo:

• izandla nezinyawo ezikhulayo
• ubuso obukhulisiwe noma obuvelele ngokungavamile
• amathegi esikhumba
• iphunga lomzimba nokujuluka okweqile
• ubuthakathaka
• izwi elizwakala linomsindo
• ikhanda
• ulimi olukhulisiwe
• ubuhlungu obuhlangene nokunyakaza okulinganiselwe
• umgqomo wesifuba
• izikhathi ezingajwayelekile
• ukungasebenzi kahle kwe-erectile

Izimpawu ze-galactorrhea noma i-prolactinoma zingafaka okulandelayo:

• amabele amathenda kwabesifazane
• amabele aqala ukukhiqiza ubisi kwabesifazane abangakhulelwe futhi kuyaqabukela kwabesilisa
• ukungasebenzi kahle kokuzala
• izikhathi ezingajwayelekile noma umjikelezo wokuya esikhathini uyeka
• ukungazali
• ukushayela ucansi okuphansi
• ukungasebenzi kahle kwe-erectile
• amazinga aphansi wamandla

Izimpawu ze-hyperthyroidism zingafaka okulandelayo:

• ukukhathazeka noma ukwethuka
• ukushaya kwenhliziyo okusheshayo
• ukushaya kwenhliziyo okungajwayelekile
• ukukhathala
• ubuthakathaka bemisipha
• ukuncipha komzimba

Ziyini izimbangela?

Ukungasebenzi kahle kwendlala ye-pituitary efana ne-hyperpituitarism kungenzeka kakhulu kubangelwe isimila. Uhlobo oluvame kakhulu lwesimila lubizwa nge-adenoma futhi alunomdlavuza.Isimila singadala ukuthi indlala yamapayipi ikhiqize ngokweqile ama-hormone. Isimila, noma uketshezi olugcwalisa nxazonke, lungaphinde lucindezele kwindlala ye-pituitary. Le ngcindezi ingaholela ekukhiqizweni kwehomoni eningi kakhulu noma ekukhiqizweni okuncane kakhulu, okubangela i-hypopituitarism.

Ayaziwa imbangela yalezi zinhlobo zamathumba. Kodwa-ke, imbangela yalesi sifo kungenzeka ifuzo. Ezinye izicubu zofuzo zibangelwa yisimo esaziwa ngokuthi ama-endocrine neoplasia syndromes amaningi.

Izinketho zokwelashwa

Ukwelashwa kwe-hyperpituitarism kuzohluka ngokuya ngokutholakala kwesimo esikudingayo. Noma kunjalo, ukwelashwa kungafaka okukodwa noma okuningi kokulandelayo:

Imithi

Uma isimila sibangela i-hyperpituitarism yakho umuthi ungasetshenziswa ukusinciphisa. Lokhu kungenziwa ngaphambi kokuhlinzwa ukuze kususwe isimila. Imithi ingasetshenziswa futhi kulesimila uma ukuhlinzwa kungeyona inketho yakho. Kwezinye izimo ze-hyperpituitarism, imithi ingasiza ukuyiphatha noma ukuyiphatha.

Izimo ezingadinga umuthi wokuphathwa noma ukwelashwa zifaka:

• Iprolactinoma. Imithi yehlisa amazinga akho e-prolactin.
• I-Acromegaly noma i-gigantism. Imithi inganciphisa inani lama-hormone okukhula.

Ukuhlinzwa

Ukuhlinzwa kwenziwa ukuze kususwe isimila esisemgodini we-pituitary. Lolu hlobo lokuhlinzwa lubizwa nge-transsphenoidal adenomectomy. Ukuze ususe isimila, udokotela wakho ohlinzayo uzosika kancane odebeni lwakho oluphezulu noma ekhaleni. Lokhu kuqhekeka kuzovumela udokotela ohlinzayo ukuthi afike endlaleni yesikhumba futhi asuse isimila. Lapho lwenziwa udokotela ohlinzayo onolwazi, lolu hlobo lokuhlinzwa lunempumelelo engaphezu kwamaphesenti angama-80.

Imisebe

Imisebe enye indlela uma ungakwazi ukuhlinzwa ukuze ususe isimila. Kungasiza futhi ukususa noma yiziphi izicubu zesimila okungenzeka ukuthi zashiywa ngemuva kokuhlinzwa kwangaphambilini. Ngokwengeziwe, imisebe ingasetshenziselwa izicubu ezingaphenduli emithini. Kunezinhlobo ezimbili zemisebe engasetshenziswa:

• Ukwelashwa okuvamile kwemisebe. Imithamo emincane inikezwa isikhathi esingamasonto amane kuya kwayisithupha. Izicubu ezizungezile zingalimala phakathi nalolu hlobo lokwelashwa ngemisebe.
• Ukwelashwa kwe-stereotactic. Igongolo lemisebe yomthamo omkhulu lihloselwe isimila. Lokhu kuvame ukwenziwa ngesikhathi esisodwa. Uma kwenziwa ngeseshini eyodwa, mancane amathuba okulimaza izicubu ezizungezile. Kungadinga ukwelashwa okuqhubekayo kokushintsha i-hormone ngemuva kwalokho.

Kutholakala kanjani?

Ukuhlolwa kokuxilongwa kwe-Hyperpituitarism kuyahluka ngokuya ngezimpawu zakho nomlando wezokwelapha. Ngemuva kokuxoxa ngezimpawu zakho nokukunikeza ukuhlolwa komzimba, udokotela wakho uzonquma ukuthi iziphi izivivinyo zokuxilonga okufanele zisetshenziswe. Uhlobo lwezivivinyo lungafaka:

• ukuhlolwa kwegazi
• ukuhlolwa kokubekezelelana kweglucose ngomlomo
• ukuhlolwa okukhethekile kwesampula segazi
• ukuhlolwa kwe-imaging nge-MRI noma nge-CT scan uma kusolwa isimila

Udokotela wakho angasebenzisa eyodwa noma inhlanganisela yalezi zivivinyo ukuze athole ukuxilongwa okufanele.

Izinkinga nezimo ezihambisanayo

I-Hyperpituitarism ingadala izimo ezahlukahlukene ezahlukahlukene. Lezi zimo zibandakanya okulandelayo:

• I-Cushing syndrome
• i-gigantism noma i-acromegaly
• i-galactorrhea noma i-prolactinoma
• i-hyperthyroidism

Izinkinga ze-hyperpituitarism ziyahlukahluka kuye ngokuthi kubangelwa yisiphi isimo. Enye yezinkinga ezingaba khona kulandela ukuhlinzwa ukuze kususwe isimila ukuthi ungaba nesidingo esiqhubekayo sokuphuza imishanguzo yokwelapha i-hormone.

Umbono

Umbono walabo abane-hyperpituitarism muhle. Ezinye zezimo ezingadala ukuthi zidinge imithi eqhubekayo yokuphathwa kahle kwezimpawu. Kodwa-ke, ingaphathwa ngempumelelo ngokunakekelwa okufanele, ukuhlinzwa uma kudingeka, nemithi njengoba iqondisiwe. Ukuze uthole ukwelashwa nokuphathwa okufanele, kufanele uqiniseke ukuthi uthintana nabachwepheshe bezokwelapha abanolwazi nge-hyperpituitarism.