Irritable Bowel Syndrome vs. Carcinoid Syndrome

-Delile

• Ziyini izimpawu ezinkulu zama-MCT?
• Ziyini izimpawu ze-IBS?
• Yimuphi umehluko ophambili phakathi kwe-IBS nama-MCT?
• Ubudala ekuxilongweni
• Ukuqhuma, ukuvunguza, noma ukuphefumula kanzima
• Ukwehla kwesisindo
• Izimpawu zesisu eziqhubekayo
• Ukuthatha

Odokotela baba ngcono ekuhloleni izicubu ze-carcinoid metastatic (MCTs). Kodwa-ke, izimpawu ezahlukahlukene ze-MCT kwesinye isikhathi zingaholela ekuxilongweni okungafanele nokwelashwa okungalungile, kuze kuvele isimila se-carcinoid ngemuva kwalezi zimpawu. Ngokusho kweNational Organisation for Rare Disorders, izicubu ze-carcinoid zivame ukutholwa ngokungafanele njenge-irritable bowel syndrome (IBS) noma isifo seCrohn, noma njengesibonakaliso sokunqamuka kokuya esikhathini kwabesifazane.

Ukwazi umehluko phakathi kwezimpawu zesifo se-carcinoid ne-IBS kungakunika umbono wokuthi yisiphi isimo ongaba naso, nokuthi yini okufanele uyibuze udokotela wakho ukuthola ngokuqinisekile.

Ziyini izimpawu ezinkulu zama-MCT?

Ngokusho kwephephabhuku i-American Family Physician, izimila eziningi ezibanga i-carcinoid azibangeli zimpawu. Imvamisa, udokotela ohlinzayo uthola esinye salezi zicubu ngenkathi enza ukuhlinzwa kolunye udaba, njenge-acute pancreatitis, ukuvimba ithumbu lomuntu, noma izifo ezibandakanya umgudu wokuzala wowesifazane.

Izicubu ze-carcinoid zingakhipha amahomoni amaningi athinta umzimba wakho, okubaluleke kakhulu ukuba yi-serotonin. Ukwanda kwe-serotonin emzimbeni wakho kungashukumisa amathumbu akho, kubangele izimpawu ezifana ne-IBS, ikakhulukazi isifo sohudo. Ezinye izimpawu ezihambisana nama-MCT zifaka:

• ukuqhuma
• izinkinga zenhliziyo ezidala ukushaya kwenhliziyo okungajwayelekile nezinguquko kumfutho wegazi, imvamisa kwehlisa umfutho wegazi
• imisipha namalunga
• isifuba

Uhudo oluhambisana nama-MCTs luvame ukuba lubi kakhulu ngemuva kokuthi umuntu adle ukudla okuqukethe into ebizwa nge-tyramine. Ukudla okune-tyramine kufaka iwayini, ushizi noshokoledi.

Ngokuhamba kwesikhathi, izimpawu zesisu ezihlobene nama-MCTs zingaba neminye imiphumela eyingozi. Lokhu kufaka ukulahleka kwesisindo ngoba indle idlula ngokushesha emathunjini akho kangangokuba umzimba wakho awunaso isikhathi sokumunca izakhamzimba. Ukwehla kwamanzi emzimbeni nokungondleki nakho kungenzeka ngezizathu ezifanayo.

Ziyini izimpawu ze-IBS?

I-IBS yisimo esithinta amathumbu amakhulu, okudala ukucasuka okungaholela ekucasukeni okungapheli kwesisu. Izibonelo zezimpawu ezihambisana ne-IBS zifaka:

• ukuqunjelwa
• ukunyanyiswa
• isifo sohudo
• igesi
• ubuhlungu besisu

Abanye abantu abane-IBS babhekana nokushintshana kokuqunjelwa nohudo. Njenge-MCT, i-IBS ivame ukwenziwa ibe yimbi kakhulu uma umuntu edla izinhlobo ezithile zokudla, njengoshokoledi notshwala. Okunye ukudla okwaziwa ukudala izimpawu ze-IBS kufaka:

• imifino ye-cruciferous efana ne-broccoli, ukholifulawa kanye neklabishi
• ukudla okubabayo
• ukudla okunamafutha amaningi
• ubhontshisi
• imikhiqizo yobisi

I-IBS ayibangeli ukulimala komzimba emathunjini. Lapho umuntu enezimpawu ezinzima, udokotela angenza i-biopsy yamathumbu abo ukuze afune ukulimala noma isifo. Yilapho udokotela angathola khona i-MCT, uma ikhona.

Yimuphi umehluko ophambili phakathi kwe-IBS nama-MCT?

Uma ucabanga ngezimpawu ze-IBS, kulula ukubona ukuthi i-MCT ingahle ihlolwe kanjani njenge-IBS. Kodwa-ke, izici ezithile ezibalulekile zingaholela kudokotela ukuthi ancome izivivinyo zokuxilonga ukuze ahlolele i-MCT.

Ubudala ekuxilongweni

Ngenkathi umuntu angathola i-IBS nganoma yisiphi isikhathi, abesifazane abangaphansi kweminyaka engama-45 banamathuba amaningi okutholakala ukuthi ane-IBS, ngokusho kweMayo Clinic. Ngokuphambene nalokho, isilinganiso seminyaka umuntu one-MCT uqala ukubona izimpawu ziphakathi kuka-50 no-60.

Ukuqhuma, ukuvunguza, noma ukuphefumula kanzima

Umuntu one-MCT angabhekana nokushaywa yisifo sohudo bese efaka lezi zingqinamba ezinkingeni ezahlukahlukene. Isibonelo, bangasola ukuphefumula emakhazeni kanye nohudo lwabo ku-IBS. Kodwa-ke, izimpawu ezihambisana nama-MCTs azihlali zigxile ohlelweni olulodwa emzimbeni womuntu.

Ukwazi lokhu, kubalulekile ukuthi uchaze zonke izimpawu ezingajwayelekile ohlangabezana nazo kudokotela wakho, noma ngabe zibonakala zingahlobene. Isibonelo, kufanele wabelane uma ngabe uhlangabezane hhayi nohudo kuphela, kepha futhi nokugulisa, ukuphefumula, noma ukuphefumula kanzima jikelele. Ikakhulukazi, isifo sohudo nokukhishwa kwenzeka ngasikhathi sinye kulabo abane-MCT.

Ukwehla kwesisindo

Ngenkathi umuntu one-IBS ezwa ukulahleka kwesisindo okuhlobene nohudo lwabo, lesi sibonakaliso kungenzeka ukuthi senzeke nge-MCTs noma esinye isimo esibi kakhulu. Ukwehla kwesisindo kubhekwa "njengophawu lwefulegi elibomvu" ukuthi imbangela eyimbangela akuyona i-IBS, ngokusho kweMayo Clinic.

Izimpawu zesisu eziqhubekayo

Imvamisa, labo abane-MCT bazobhekana nezimpawu ezahlukahlukene zesisu iminyaka eminingi ngaphandle kokuxilongwa. Uma izimpawu zakho zingaphendulanga ekwelashweni noma kubonakala sengathi ziyathuthuka ngokususwa kwezinto eziqukethe i-tyramine ekudleni kwakho, lokhu kungaba yisiginali yokucela udokotela wakho ukuthi aqhubeke nokumba ngokuqhubekayo.

Izibonelo zezivivinyo zokuthola i-MCT zifaka:

• ukukala umchamo wakho amahora angama-24 ukuba khona kwe-5-HIAA, umkhiqizo ovela emzimbeni wakho ophula i-serotonin
• ukuhlola igazi lakho ukuthola i-chromogranin-A
• usebenzisa ukuskena kwe-imaging, njengokuhlola kwe-CT noma kwe-MRI, ukukhomba indawo engaba khona ye-MCT

Ukuthatha

Isikhathi esimaphakathi kusukela ekuqaleni kwezimpawu ze-MCT ukuxilongwa. Yize lokhu kubonakala njengesikhathi eside kakhulu, kukhombisa ukuthi kungaba nzima kanjani futhi kwesinye isikhathi kube nzima kangakanani ukuthola i-MCT.

Uma unezimpawu ezedlula ngaphezu kohudo, khuluma nodokotela wakho mayelana nokwenza i-MCT. Iningi labantu abane-MCT alifuni ukwelashwa kuze kube yilapho isimila sesisakazekile futhi siqala ukudala izimpawu ezingeziwe. Kodwa uma uthatha izinyathelo zokuhlolwa okwengeziwe kusenesikhathi futhi udokotela wakho uthola i-MCT, bangakwazi ukukhipha isimila, basivimbele ekusakazekeni.