Ingabe Kubi Ukuthatha i-Ibuprofen Esiswini Esingenalutho?

-Delile

• Kuphephile esiswini esingenalutho?
• Okuningi nge-ibuprofen
• Okuqhamuka uma udla imishanguzo
• Okufanele ukwenze uma usuvele uyithathile
• Iyiphi indlela engcono yokuthatha ibuprofen?
• Ukubonana nodokotela nini
• Okubalulekile

I-Ibuprofen ingenye yemithi ejwayelekile kakhulu ye-over-the-counter (OTC) esetshenziselwa ukwelapha ubuhlungu, ukuvuvukala nomkhuhlane. Sekuyiminyaka ecishe ibe ngu-50.

I-Ibuprofen yisidakamizwa esingaqedi ukuvuvukala (i-NSAID), futhi isebenza ngokuvimba umsebenzi we-cyclooxygenase (COX) enzyme. Umsebenzi we-COX ubhekene nokukhiqizwa kwe-prostaglandin.

Ukuthi i-ibuprofen iphephile yini ukuyidla esiswini esingenalutho kuncike ezintweni ezithile kanye nezingcuphe ezithile.

Ake sibhekisise indlela engcono kakhulu yokuthatha ibuprofen ukwenza ngcono izimpawu ngenkathi sinciphisa izingozi.

Kuphephile esiswini esingenalutho?

I-Ibuprofen inokubangela imiphumela emibi kakhulu yamathumbu (GI) jikelele. Kodwa-ke, ubungozi bukhona futhi buxhomeke kubudala bomuntu, ubude bokusebenzisa, isilinganiso, nanoma ikuphi ukukhathazeka kwezempilo okukhona.

I-Ibuprofen ingathinta amazinga e-prostaglandin futhi idale imiphumela emibi ye-GI. Umsebenzi owodwa we-prostaglandin ukuvikela isisu sayo. Iyanciphisa i-asidi esiswini futhi inyuse ukukhiqizwa kwamafinyila.

Lapho ibuprofen ithathwa ngemithamo emikhulu noma isikhathi eside, kukhiqizwa i-prostaglandin encane. Lokhu kungakhuphula i-asidi esiswini futhi kucasule ulwelwesi lwesisu, kubangele izinkinga.

Imiphumela emibi ye-GI ingaxhomeka ezicini eziningana, kufaka phakathi:

• Ubude bokusetshenziswa. Lapho uthatha ibuprofen isikhathi eside, ubungozi bezinkinga ezihlobene ne-GI, uma kuqhathaniswa nokusetshenziswa kwesikhashana kwezidingo ezisheshayo.
• Umthamo. Ukuthatha imithamo ephakeme isikhathi eside kukhulisa ubungozi bezinkinga ezihlobene ne-GI.
• Ezinye izimo zempilo. Ukuba nezimo ezithile zempilo, njengokulandelayo, kungakhuphula ubungozi bemiphumela emibi noma ukusabela okungathandeki:
  • umlando wezikhalazo ze-GI
  • izilonda ezophayo
  • isifo esingapheliyo sokuvuvukala kwamathumbu
• Izici zomuntu ngamunye. Abantu abadala banengozi ephezulu ye-GI neminye imiphumela emibi ngokusetshenziswa kwe-ibuprofen.
  • Qiniseka ukuthi uxoxa ngezinzuzo ze-ibuprofen ngokuqhathanisa nobungozi nodokotela wakho ngaphambi kokuthatha lo muthi.
  • Uma unenhliziyo, izinso, umfutho wegazi ophakeme, noma ezinye izimo zezokwelapha ezingamahlalakhona, buza udokotela wakho ngokusetshenziswa kwe-ibuprofen.

Okuningi nge-ibuprofen

Kunezinhlobo ezimbili ezihlukile ze-COX, futhi ezinayo emzimbeni. I-COX-2, uma isebenza, ivimba ukukhishwa kwe-prostaglandin ekuphenduleni ubuhlungu, umkhuhlane nokuvuvukala. I-COX-1 inomphumela wokuzivikela kulwelwesi lwesisu namaseli azungezile.

I-Ibuprofen ithinta umsebenzi we-COX-1 nowe-COX-2, ukuhlinzeka ukukhululeka kwezimpawu futhi ngasikhathi sinye okwandisa ubungozi bemiphumela ethile emibi.

kungenza umehluko ngokumunca, ukusebenza kahle, kanye nemiphumela emibi. Lokhu kufaka phakathi ukuyithatha ngokudla noma ngesisu esingenalutho.

Enye yezinselelo nge-ibuprofen ukuthi uma uyithatha ngomlomo, ayimunci ngokushesha. Kuthatha cishe imizuzu engama-30 ukusebenza. Lokhu kubalulekile uma ufuna ukukhululeka ngokushesha kobuhlungu.

Okuqhamuka uma udla imishanguzo

I-Ibuprofen ingadala imiphumela emibi eminingi ye-GI, kufaka phakathi:

• isilonda
• isilungulela
• isicanucanu nokuhlanza
• ukopha
• dabula isisu, amathumbu amancane, noma amathumbu amakhulu
• isifo sohudo
• ukuqunjelwa
• amajaqamba
• umuzwa wokugcwala
• ukuqunjelwa
• igesi

Izingozi ze-GI eziphezulu neziphansi kumele zicatshangelwe ngaphambi kokusebenzisa ibuprofen. I-Ibuprofen uma kukhona ingozi ephansi ye-GI, noma ngabe kunemithi ye-proton pump inhibitor efana ne-Nexium njengokuvikela.

yemiphumela emibi ye-GI iphezulu nge:

• abantu abaneminyaka engaphezu kwengama-65, njengamaphindaphindwe amane
• umlando wokugaya ukudla noma isilungulela
• ukusetshenziswa kwama-corticosteroids, ama-anticoagulants afana ne-warfarin (Coumadin), ama-serotonin reuptake inhibitors (SSRIs) akhethiwe njenge-sertraline (Zoloft), ama-antiplatelets afana ne-aspirin noma i-clopidogrel (i-Plavix)
• i-peptic ulcer noma ukuphuma kwegazi okuhlobene nesilonda
• ukusetshenziswa kotshwala, njengoba kungacasula ulwelwesi lwesisu, futhi ukusebenzisa ibuprofen ngotshwala kungandisa ubungozi bokuphuma esiswini

Okufanele ukwenze uma usuvele uyithathile

Khumbula, eminye imithi ihlangana ne-ibuprofen nezimo zezempilo. Qiniseka ukuthi uxoxa ngezindlela ezingcono kakhulu zokunciphisa ubungozi bezinkinga ze-GI nodokotela wakho kuqala.

Uma uhlangabezana nezimpawu ezincane zesisu, imithi ethile yokuvikela ingasiza:

• I-antacid esekwe ku-magnesium ingasiza ngezimpawu ezincane zesilungulela noma i-acid reflux. Gwema ukuthatha ama-antacids asuselwa ku-aluminium ne-ibuprofen, ngoba aphazamisa ukumuncwa kwe-ibuprofen.
• Iproton pump inhibitor efana ne-esomeprazole (Nexium) ingasiza nge-acid reflux. Qiniseka ukuthi ubuza nosokhemisi wakho nganoma yimiphi imiphumela emibi noma ukuxhumana kwezidakamizwa.

Isexwayiso: Ungathathi izinhlobo eziningi zokunciphisa i-asidi ngasikhathi sinye. Uma izimpawu zakho zingathuthuki noma ziba zimbi kakhulu, khuluma nodokotela wakho.

Iyiphi indlela engcono yokuthatha ibuprofen?

Indlela engcono kakhulu yokuthatha ibuprofen incike kubudala bakho nezici zobungozi. khombisa ukuthatha ibuprofen ngesivikeli esiswini njenge-PPI kuyindlela ephumelelayo yokugwema izilonda ezine-peptic, uma uyithatha ngemithamo ephakeme isikhathi eside.

Uma uthatha i-ibuprofen yokuqeda ubuhlungu besikhashana futhi ungenazo izinto eziyingozi, ungakwazi ukuyithatha esiswini esingenalutho ukuze uthuthuke ngokushesha. Isivikelo esine-magnesium singasiza ngokukhululeka ngokushesha.

Ukubonana nodokotela nini

Kubalulekile ukufuna usizo lwezempilo ngokushesha uma:

• babe nezitulo zokubambezela ezimnyama
• zihlanza igazi
• ube nobuhlungu obukhulu besisu
• ube nesicanucanu esiqhubekayo nokuhlanza
• ube negazi emchameni wakho
• ube nezinhlungu esifubeni
• unenkinga ngokuphefumula

Shayela ku-911 ngokushesha uma uhlangabezana:

• ukuqubuka
• ukuvuvukala kobuso, ulimi, umphimbo, noma izindebe
• ukuphefumula kanzima
• isifuba

Okubalulekile

Imiphumela emibi yamathumbu yinkinga ejwayelekile kakhulu ebikwe nge-ibuprofen. Kubalulekile ukuqonda izinkinga ezinkulu noma ezinzima ze-GI, njengokuphuma kwegazi, kungenzeka ngaphandle kwezimpawu zokuxwayisa.

Qiniseka ukuthi uxoxa ngomlando wakho wezinto ezihlobene ne-GI nomhlinzeki wakho wezokunakekelwa kwempilo ngaphambi kokuthatha ibuprofen uwedwa. Uma ukhulelwe, khuluma nodokotela wakho ngaphambi kokuthatha ibuprofen.

Ezimweni ezikhawulelwe, ukuthola ukukhululeka okusheshayo kwezimpawu zobuhlungu, ukuthatha ibuprofen esiswini esingenalutho kungaba kuhle. I-antacid equkethe i-magnesium inganikela ngokuvikela okuthile futhi isize ukuhlinzeka ngokukhululeka okusheshayo.

Ukusetshenziswa kwesikhathi eside, kuyasiza ukuthatha isivikeli ukugwema imiphumela emibi ye-GI. Kwezinye izimo, udokotela wakho uzokhetha inketho ehlukile yemithi.