I-Insulin-Like Growth Factor (IGF): Okufanele Ukwazi

-Delile

• Yikuphi ukuxhumana phakathi kwesifo sikashukela kanye ne-IGF?
• Yikuphi ukuhlolwa okutholakala ku-IGF?
• Ungayisebenzisa i-IGF ukwelapha isifo sikashukela?
• Kuthiwani nge-IGF kuma-supplements?
• Uyini umbono?

Kuyini ukukhula okufana ne-insulin (IGF)?

IGF iyi-hormone ukuthi umzimba wakho wenza ngokwemvelo. Bekade kwaziwa njenge-somatomedin. IGF, evela ikakhulu esibindini, isebenza kakhulu njenge-insulin.

IGF kusiza ukulawula ozokusebenzisa uketshezi endlaleni pituitary. IGF isebenza ngama-hormone okukhula ukukhuthaza ukukhula nokuthuthuka kwamathambo nezicubu. Lawa mahomoni athinta nokuthi umzimba wakho ugaya kanjani ushukela, noma i-glucose. I-IGF ne-insulin kungasebenzisana ukwehlisa ngokushesha izinga likashukela egazini lakho.

Yikuphi ukuxhumana phakathi kwesifo sikashukela kanye ne-IGF?

Uma unesifo sikashukela, umzimba wakho awenzi i-insulin eyanele noma awukwazi ukusisebenzisa kahle. Udinga i-insulin ukucubungula ushukela ukuze uthole amandla. I-insulin isiza ukusabalalisa i-glucose kumaseli emzimbeni wakho wonke ngenkathi inciphisa i-glucose egazini lakho.

Yikuphi ukuhlolwa okutholakala ku-IGF?

Ukuhlolwa kwegazi okulula kungacacisa ukuthi une-IGF engakanani egazini lakho.

Odokotela bangabuye ba-oda lokhu kuhlolwa lapho ingane ingakhuli noma ikhula njengoba kulindelwe iminyaka yayo.

Kubantu abadala, lokhu kuhlolwa kungenzeka ukuthi kwenziwe ukuze kubhekwe ukuphazamiseka kwezindlala zepituitary noma izicubu. Akunikezwa njalo kubantu abanesifo sikashukela.

I-IGF ilinganiswa ngama-nanograms ngemililitha ngayinye (ng / mL). Amabanga ajwayelekile yile:

• I-182-780 ng / mL yabantu abaneminyaka engu-16-24
• 114-492 ng / mL kubantu abaneminyaka engu-25-39
• I-90-360 ng / mL yabantu abaneminyaka engama-40-54
• 71-290 ng / mL yabantu abangu-55 nangaphezulu

Uma imiphumela yakho yokuhlolwa ikhombisa amazinga aphezulu noma aphansi kunebanga elijwayelekile, kungaba nezincazelo eziningana, kufaka phakathi:

• amazinga aphansi e-thyroid, noma i-hypothyroidism
• isifo sesibindi
• isifo sikashukela esingalawulwa kahle

Uma amazinga akho e-IGF engekho ebangeni elijwayelekile, akusho ukuthi kukhona okungahambi kahle. Udokotela wakho uzokwazi ukunikeza incazelo ngokuya ngemininingwane ebanzi yolwazi.

Izinga eliphakeme le-IGF lingakhuphula ubungozi bakho kumdlavuza we-colorectal, webele ne-prostate, yize kungekho zifundo zakamuva ezibuyekeze lokhu kuxhumana. I-insulini abantu abayisebenzisayo ukwelapha uhlobo lwesifo sikashukela sohlobo lwesibili nayo ingakhuphula ubungozi bemidlavuza ethile.

Ungayisebenzisa i-IGF ukwelapha isifo sikashukela?

IMecasermin (i-Increlex) inguqulo yokufakelwa ye-IGF. Kungumuthi kadokotela owusebenzisayo ukwelapha ukwehluleka kokukhula ezinganeni. Omunye wemiphumela emibi engaba khona ye-mecasermin yi-hypoglycemia. Uma une-hypoglycemia, lokho kusho ukuthi une-glucose ephansi yegazi.

Ucwaningo lukhombisa ukuthi i-IGF iyakwazi ukucindezela isifo sikashukela sohlobo 1 kumagundane. Kuhlobo lwesifo sikashukela sohlobo 1, amasosha omzimba ayaziphendukela, ahlasele amaseli we-beta kumanyikwe akhiqiza i-insulin. I-IGF ingakwazi ukuzivikela ekuhlaselweni ngumzimba uqobo.

Ezinye izifundo zikhombisile ukuthi ukwelashwa nge-IGF kungasiza ekulawuleni isifo sikashukela. Ayikaze yenzelwe ukwelashwa kwesifo sikashukela ngenxa yemiphumela emibi kakhulu, kufaka phakathi:

• ukuvuvukala kwemizwa ye-optic
• ukuphindaphinda kwengqondo
• ubuhlungu bemisipha
• ubuhlungu obuhlangene

Ngenkathi ucwaningo oluthembisayo lukhona, ubudlelwano phakathi kwe-IGF nesifo sikashukela buyinkimbinkimbi. Ucwaningo oluningi luyadingeka ngaphambi kokuba odokotela basebenzise i-IGF ukwelapha lesi sifo esiyinkimbinkimbi.

Kuthiwani nge-IGF kuma-supplements?

Izithako zokudla ezahlukahlukene ziqukethe ama-hormone okukhula, kufaka phakathi i-IGF. Izinkampani zibakhuthaza ngokulwa nokuguga, amandla, nokwenza ngcono amasosha omzimba, phakathi kwezinye izimangalo.

I-U.S. Anti-Doping Agency ixwayisa ngokuthi imikhiqizo ethi iqukethe i-IGF-1 ingahle ingenayo. Kungabuye kuhlanjululwe noma umkhiqizo ungaqukatha ezinye izinto ezingaba yingozi. Abantu bangasebenzisa futhi kabi i-IGF-1.

Imiphumela emibi ye-IGF-1 ingahle ifane naleyo yamanye ama-hormone okukhula. Lokhu kufaka phakathi ukwanda kwezicubu zomzimba, ezaziwa njenge-acromegaly, nokulimala kwamalunga, isibindi nenhliziyo.

IGF-1 kungabangela amazinga eglucose egazini lakho ukwehla. Uma unesifo sikashukela, noma noma ungenaso, kubalulekile ukuthi ubuze nodokotela wakho ngaphambi kokuthatha izithasiselo eziqukethe noma yimaphi ama-hormone okukhula.

Uyini umbono?

Ucwaningo lukhombisa ukuthi i-IGF ingahle ixhunywe nesifo sikashukela, kepha abantu abakuqondi kahle ukuxhumana. Ungahle ukwazi ukwelapha isifo sakho sikashukela nge-IGF, kepha lokhu kusalinga.

Khuluma nodokotela wakho ngaphambi kokuthatha i-IGF noma ngaphambi kokuzama ezinye izithako, futhi ungaguquli uhlelo lwakho lwezokwelapha ngaphandle kokukhuluma nodokotela wakho. Isifo sikashukela yisifo esiyinkimbinkimbi, futhi singadala izinkinga eziningi uma ungakutholi ukwelashwa kwaso.