I-Juvenile Idiopathic Arthritis

-Delile

• Ziyini izimpawu ze-juvenile idiopathic arthritis?
• Yiziphi izinhlobo ze-juvenile idiopathic arthritis?
• Sitholakala kanjani isifo samathambo esentsha se-idiopathic?
• Selashwa kanjani i-juvenile idiopathic arthritis?
• Ukwelashwa
• Izindlela zokuphila
• Ukudla kahle
• Ukuzivocavoca umzimba njalo
• Ukwelashwa ngokomzimba
• Yiziphi izinkinga ezingaba khona ze-juvenile idiopathic arthritis?
• Uyini umbono wezingane ezine-juvenile idiopathic arthritis?

Yini i-juvenile idiopathic arthritis?

I-juvenile idiopathic arthritis (JIA), phambilini ebibizwa nge-juvenile rheumatoid arthritis, iyona nhlobo i-arthritis evame kakhulu ezinganeni.

I-arthritis yisimo sesikhathi eside esibonakala nge:

• ukuqina
• ukuvuvukala
• ubuhlungu bamalunga

Izingane ezilinganiselwa ku-300,000 e-United States zine-arthritis. Ezinye izingane zinesifo samathambo izinyanga ezimbalwa nje, kanti ezinye zinesifo samathambo iminyaka eminingana. Ezimweni ezingavamile, isimo singahlala impilo yonke.

Imbangela ngqo ye-JIA ayaziwa. Kodwa-ke, abacwaningi bakholelwa ukuthi ngokuyinhloko isifo esizimele. Kubantu abanezifo ezizimele, amasosha omzimba ahlasela ngephutha amangqamuzana angenangozi njengokungathi angabahlaseli abayingozi.

Izimo eziningi ze-JIA zimnene, kepha amacala abucayi angaholela ezinkingeni, njengokulimala ngokuhlanganyela nobuhlungu obungapheli. Ukwazi izimpawu ze-JIA kubalulekile ekutholeni ukwelashwa ngaphambi kokuthi isimo siqhubeke.

Ukwelashwa kuvame ukuqukethe:

• ukunciphisa ukuvuvukala
• ukuphatha ubuhlungu
• ukwenza ngcono umsebenzi
• ukuvimbela ukulimala okuhlangene

Lokhu kungasiza ekuqinisekiseni ukuthi ingane yakho igcina ikhuthele, ikhiqiza impilo.

Ziyini izimpawu ze-juvenile idiopathic arthritis?

Izimpawu ezivame kakhulu ze-JIA zifaka:

• ubuhlungu obuhlangene
• ukuqina
• kunciphise ububanzi bokunyakaza
• amalunga afudumele futhi avuvukile
• ngixhuga
• ububomvu endaweni ethintekile
• ama-lymph node avuvukile
• imikhuhlane ephindaphindayo

I-JIA ingathinta ukujoyina okukodwa noma amajoyinti amaningi. Kwezinye izimo, lesi simo singathinta wonke umzimba, sibangele ukuqubuka, umkhuhlane nokuvuvukala kwama-lymph node. Le subtype ibizwa ngokuthi i-systemic JIA (SJIA), futhi kwenzeka cishe kumaphesenti ayi-10 ezingane ezine-JIA.

Yiziphi izinhlobo ze-juvenile idiopathic arthritis?

Kunezinhlobo eziyisithupha ze-JIA:

• I-JIA ehlelekile. Lolu hlobo lwe-JIA luthinta wonke umzimba, kufaka phakathi amalunga, isikhumba nezitho zangaphakathi.
• I-Oligoarticular JIA. Lolu hlobo lwe-JIA luthinta amalunga angaphansi kwamahlanu. Kwenzeka cishe engxenyeni yazo zonke izingane ezine-arthritis.
• I-Polyarticular JIA. Lolu hlobo lwe-JIA luthinta amalunga amahlanu noma ngaphezulu. Iphrotheni eyaziwa ngokuthi i-rheumatoid factor kungenzeka noma ingabikhona.
• I-juvenile psoriatic arthritis. Lolu hlobo lwe-JIA luthinta amalunga futhi lwenzeka nge-psoriasis, yingakho ibizwa ngokuthi yi-juvenile psoriatic arthritis.
• I-JIA ehlobene ne-Enthesitis. Lolu hlobo lwe-JIA lubandakanya ukuhlangana kwamathambo nemisipha nemisipha.
• Isifo samathambo esingafani. Lolu hlobo lwe-JIA lubandakanya izimpawu ezingadlulela ama-subtypes amabili noma ngaphezulu noma zingalingani amanye ama-subtypes.

Uma amalunga athintekile kakhulu, imvamisa isifo siba sibi kakhulu.

Sitholakala kanjani isifo samathambo esentsha se-idiopathic?

Umhlinzeki wezokunakekelwa kwezempilo wengane yakho angakwazi ukuxilonga i-JIA ngokwenza ukuhlolwa okuphelele komzimba futhi acele umlando wezempilo onemininingwane.

Bangaphinde ba-oda izivivinyo ezahlukahlukene zokuxilonga, njenge:

• Ukuhlolwa kwamaprotheni asebenzayo ngo-C. Lokhu kuhlolwa kukala inani lamaprotheni asebenza ngo-C (CRP) egazini. I-CRP yinto eyenziwa yisibindi ekuphenduleni ukuvuvukala. Olunye uvivinyo oluthola ukuvuvukala, isilinganiso sedimentation noma isilinganiso se-erythrocyte sedimentation (ESR), singenziwa futhi.
• Isivivinyo se-Rheumatoid factor. Lokhu kuhlolwa kuthola ubukhona be-rheumatoid factor, i-antibody ekhiqizwa amasosha omzimba. Ukuba khona kwaleli antibody kuvame ukukhombisa isifo samathambo.
• I-antibody ye-Antinuclear. I-antibody ye-Antinuclear i-antibody ye-nucleic acid (i-DNA ne-RNA) etholakala ikakhulu ku-nucleus yeseli. Kuvame ukwenziwa amasosha omzimba kubantu abanesifo sokuzimela. Ukuhlolwa kwamasosha omzimba enyukliya kungakhombisa ukuthi ngabe amaprotheni akhona egazini.
• Ukuhlolwa kwe-HLA-B27. Lokhu kuhlola kuthola umaka wofuzo ohlotshaniswa ne-JIA ehlobene ne-enthesitis.
• I-X-ray noma i-MRI scan. Lokhu kuhlolwa kwe-imaging kungasetshenziselwa ukukhipha ezinye izimo ezingadala ukuvuvukala okuhlangene noma ubuhlungu, njengokungenwa yizifo kanye nokwaphuka. Ukufanekisa kungabuye kuveze okutholakele okuthile (izimpawu) zama-subsets we-arthritis yokuvuvukala.

Selashwa kanjani i-juvenile idiopathic arthritis?

Ukwelashwa okuhlukahlukene kungaphatha ngempumelelo futhi kunciphise imiphumela ye-JIA. Abahlinzeki bezokunakekelwa kwempilo bavame ukuncoma inhlanganisela yokwelashwa ukudambisa izinhlungu nokuvuvukala nokugcina ukunyakaza namandla.

Ukwelashwa

Izidakamizwa ezingezona ukuvuvukala (ama-NSAID), njenge-ibuprofen (Advil) ne-naproxen (Aleve), zivame ukusetshenziselwa ukunciphisa ukuvuvukala nokuvuvukala ngokuhlangana nezinye izindlela zokwelapha. Ukusebenzisa i-aspirin akuvamile ngenxa yemiphumela emibi engaba khona ezinganeni.

Imithi eqinile ijwayele ukunikezwa, njengezidakamizwa zokuguqula izifo (i-DMARD) kanye ne-biologics.

Ama-DMARD asebenzela ukuguqula inkambo yalesi sifo, kulokhu ecindezela amasosha omzimba ukusivikela ekuhlaseleni amalunga.

Ukusebenzisa ama-DMARD kunconywe ngaphezu kwama-NSAID wedwa. Umhlinzeki wezokunakekelwa kwezempilo wengane yakho angaqala ukwelashwa ngama-DMARD ngama-NSAID noma ngaphandle kwama-NSAID ngaphambi kokusebenzisa i-biologics.

Ezinye izibonelo zama-DMARD asetshenziselwa ukwelapha i-JIA zifaka:

• imethotrexate
• sulfasalazine
• leflunomide

Kubalulekile ukuqaphela ukuthi i-methotrexate njengamanje inconywa ngaphezu kwamanye ama-DMARD.

I-Biologics isebenza ukukhomba ngqo ama-molecule athile noma amaprotheni abandakanyeka kwinqubo yesifo. Ukwelashwa nge-biologics kungahlanganiswa nokwelashwa kwe-DMARD.

Ezinye izibonelo ze-biologics ezingasetshenziswa ukusiza ukunciphisa ukuvuvukala nomonakalo ohlangene zifaka:

• i-abatacept (i-Orencia)
• i-rituximab (Rituxan)
• i-tocilizumab (Actemra)
• I-TNF inhibitors (Humira)

Umuthi we-steroid ungafakwa kwilunga elithintekile, ikakhulukazi lapho izimpawu ziphazamisa amandla okwenza imisebenzi yansuku zonke. Kodwa-ke, lokhu akunconywa lapho kuhlanganiswa amalunga amaningi. Ezimweni ezimbi kakhulu, ukuhlinzwa kungasetshenziselwa ukufaka amalunga ngokuphelele.

Izindlela zokuphila

Ukuvivinya umzimba nokugcina ukudla okunempilo kubalulekile kuwo wonke umuntu, kodwa kuzuzisa ikakhulukazi izingane ezine-JIA. Ukuba nengane yakho yenza lezi zinguquko ezilandelayo zokuphila kungazisiza ukuthi zibhekane nezimpawu zazo kalula futhi zinciphise ubungozi bezinkinga:

Ukudla kahle

Izinguquko zesisindo zivamile ezinganeni ezine-JIA. Imithi ingakhuphula noma yehlise isifiso sayo sokudla, ibangele ukuzuza kwesisindo esisheshayo noma ukwehlisa isisindo. Ezimweni ezinjalo, ukudla okunempilo okuqukethe inani elifanele lama-calories kungasiza ingane yakho ukuba igcine isisindo somzimba esifanele.

Khuluma nomhlinzeki wakho wezokunakekelwa kwempilo ngohlelo lokudla uma ingane yakho ithola noma ilahlekelwa isisindo esiningi ngenxa ye-JIA.

Ukuzivocavoca umzimba njalo

Ukuzivocavoca okungenani kathathu ngesonto kungaqinisa imisipha futhi kuthuthukise ukuguquguquka okuhlangene, okwenza kube lula ukubhekana ne-JIA ngokuhamba kwesikhathi. Ukuzivocavoca okunomthelela ophansi, njengokubhukuda nokuhamba ngezinyawo, kuvame ukuba ngcono kakhulu. Kodwa-ke, kuwumqondo omuhle ukukhuluma nomhlinzeki wezokunakekelwa kwezempilo wengane yakho kuqala.

Ukwelashwa ngokomzimba

Udokotela ongokomzimba angafundisa ingane yakho ukubaluleka kokunamathela enkambisweni yokuzivocavoca futhi angancoma nokuzivocavoca umzimba okufanele isimo sawo esithile. Uchwepheshe angaphakamisa izivivinyo ezithile ezingasiza ekwakheni amandla futhi zibuyise ukuguquguquka kwamalunga aqinile, abuhlungu.

Bazosebenzisana nomhlinzeki wakho oyinhloko wezokunakekelwa kwempilo ukusiza ukuvimbela ukulimala okuhlangene kanye nokukhubazeka kwamathambo / okuhlangene.

Yiziphi izinkinga ezingaba khona ze-juvenile idiopathic arthritis?

I-JIA engalashwa ingaholela kwezinye izinkinga. Lokhu kufaka phakathi:

• i-anemia
• ubuhlungu obuhlala njalo besikhathi eside
• ukubhujiswa ngokuhlanganyela
• ukukhula okungakhuli
• izitho ezingalingani
• izinguquko embonweni
• i-pericarditis, noma ukuvuvukala okuzungeze inhliziyo

Uyini umbono wezingane ezine-juvenile idiopathic arthritis?

Izingane ezine-JIA emnene kuya kokulingene ngokuvamile zingalulama ngaphandle kwezinkinga. Kodwa-ke, i-JIA yisimo sesikhathi eside esivame ukudala ukuqhuma ngezikhathi ezithile. Ingane yakho ingalindela ukuba nobulukhuni nobuhlungu emajoyinini phakathi nalokhu kuqubuka.

Lapho i-JIA seyithuthuke kakhulu, amathuba okungena ekuxolelweni asephansi kakhulu. Kungakho ukuxilongwa nokwelashwa kusenesikhathi kubalulekile.Ukwelashwa ngokushesha kungavimbela isifo samathambo ekubeni kubi kakhulu futhi kusabalale kwamanye amalunga.