Kadcyla

-Delile

• Izinkomba zeKadcyla
• Intengo yeKadcyla
• Ungayisebenzisa kanjani iKadcyla
• Imiphumela emibi yeKadcyla
• Ukungafani kweKadcyla

IKadcyla yisidakamizwa esikhonjiswe ekwelashweni komdlavuza webele onama-metheshes ambalwa emzimbeni. Lo muthi usebenza ngokuvimbela ukukhula nokwakhiwa kwamaseli amasha womdlavuza.

IKadcyla ngumuthi okhiqizwa yinkampani eyenza imithi iRoche.

Izinkomba zeKadcyla

IKadcyla ikhonjisiwe ekwelapheni umdlavuza webele osuvele usesigabeni esithuthukile futhi osuvele ususakazekele kwezinye izingxenye zomzimba. Imvamisa inikezwa isiguli ngemuva kokuba eminye imithi yomdlavuza inikezwe futhi ingaphumeleli.

Isidakamizwa iKadcyla sakhiwe yimithi emibili, i-trastuzumab evimbela ukukhula kwamangqamuzana omdlavuza kanye ne-mertansine engena kumaseli bese iyawaqeda, kunciphisa isimila nokuqhubeka kwesifo, kanye nokwelula impilo yesiguli.

Intengo yeKadcyla

Intengo yeKadcyla ngenyanga ingu- $ 9800, ngenkambo yezinyanga eziyi-9.6 yokwelashwa ebiza u- $ 94,000.

Ungayisebenzisa kanjani iKadcyla

Umthamo onconywayo weKadcyla ngu-3.6 mg / kg futhi ulawulwa ngomjovo we-intravenous njalo emavikini amathathu.

Ekwelashweni kokuqala, umuthi kufanele unikezwe imizuzu engama-90, kuthi iziguli zigadiwe ukubheka ukubonakala kwemiphumela emibi. Uma ubekezelela kahle, umuthi kufanele unikezwe okungenani imizuzu engama-30.

Imithamo emikhulu kuno-3.6 mg / kg akufanele iphathwe.

Imiphumela emibi yeKadcyla

Imiphumela emibi yeKadcyla yile:

• Ukukhathala;
• Isicanucanu nokuhlanza:
• Ubuhlungu bemisipha;
• Ukwehliswa kwenani lamaplatelets egazini;
• Ikhanda;
• Ukwanda kwe-transaminases yesibindi;
• Kuyabanda.

Ukungafani kweKadcyla

IKadcyla iyaphikiswa ngesikhathi sokukhulelwa ngoba ibanga izinkinga zofuzo ezinkulu nezisongela impilo enganeni.

Eminye imithi ingaxhumana noKadcyla njenge

• Imatinib;
• Isoniazid;
• I-Clarithromycin ne-telithromycin;
• Izidakamizwa ezibulalayo;
• Imithi yenhliziyo: i-nicardipine, i-quinidine;
• Imithi yokwelashwa kwesibindi kohlobo C: boceprevir, telaprevir;
• Izidakamizwa zengculazi;
• Amavithamini nemikhiqizo yemvelo.

Udokotela kufanele aziswe njalo ngemithi esetshenziswa njalo yisiguli noma ayiphuzayo ngesikhathi eqala ukwelashwa.