Umlobi: Lewis Jackson
Usuku Lokudalwa: 10 Mhlawumbe 2021
Ukuvuselela Usuku: 19 Unovemba 2024
Anonim
HDL Metabolism: Reverse cholesterol transport: Why HDL cholesterol is good cholesterol?
Ividiyo: HDL Metabolism: Reverse cholesterol transport: Why HDL cholesterol is good cholesterol?

-Delile

Kwenzenjani?

I-Phosphatidylcholine (PC) iyi-phospholipid enamathiselwe kunhlayiya ye-choline. I-Phospholipids iqukethe okunamafutha acid, i-glycerol, ne-phosphorus.

Ingxenye ye-phosphorus yento ye-phospholipid - i-lecithin - yenziwe nge-PC. Ngalesi sizathu, amagama athi i-phosphatidylcholine ne-lecithin avame ukusetshenziswa ngokungafani, yize ehlukile. Ukudla okuqukethe i-lecithin yimithombo yokudla engcono kakhulu ye-PC.

Yize i-PC ngokwesiko isetshenziselwa ukuxhasa impilo yobuchopho, ingaphinde isekele ukusebenza kwesibindi futhi igcine amazinga e-cholesterol ehlolile. Funda kabanzi ukuze ufunde ukuthi ucwaningo luthini ngezinzuzo zalesi sengezo sokudla okunempilo.

1. Kungasiza ukukhulisa umsebenzi wokuqonda

Ngokuya nge-a, i-PC supplementation ingakhuphula i-neurotransmitter acetylcholine ebuchosheni. Kungabuye kuthuthukise inkumbulo. Ucwaningo luthole ukuthi amagundane ngaphandle kokuwohloka komqondo awanakho ukwanda kwenkumbulo, yize kwanda amazinga e-acetylcholine.

Ucwaningo lwango-2001 lwathola ukondla amagundane ukudla okunothe ku-PC novithamini B-12 nakho kwaba nomthelela omuhle empilweni yobuchopho. Yize le miphumela ithembisa, kudingeka ukutadisha okwengeziwe.


Ucwaningo luqhubekile, kanti ucwaningo lwango-2017 luthole ukuthi amazinga e-phosphatidylcholine ahlobene ngqo nesifo i-Alzheimer's.

2. Kungasiza ekulungisweni kwesibindi

Ukudla okunamafutha amaningi kuyaziwa ukuthi kuthinta kabi isibindi. Kungadala isifo esinesibindi esinamafutha noma i-cirrhosis yesibindi. Ngokuya ngocwaningo lwango-2010, i-PC isize ukunciphisa ama-lipids angaholela esibindi esinamafutha (hepatic lipids) kumagundane adlisa ukudla okunamafutha amaningi.

Olunye ucwaningo kumagundane lubukeze ukuthi ukubuyisa amazinga aphakeme e-PC abuyele kokujwayelekile kusiza ukuvimbela isifo sesibindi esinamafutha. Ucwaningo luthole ukuthi lusize ekunqandeni ukuqongelela kwamafutha esibindini. Kodwa-ke, ayizange ivimbele isifo sesibindi esinamafutha angenalo utshwala.

3. Kungasiza ekuvikeleni kwimiphumela emibi yemithi

Eminye imishanguzo, njengezidakamizwa ezingezona ukuvuvukala (ama-NSAID), ingadala imiphumela emibi yamathumbu ngokusetshenziswa okunwetshiwe. Lokhu kufaka phakathi ubuhlungu besisu, ukopha esiswini, kanye nokugcotshwa kwamathumbu.


Ngokusho kwe-, ukusetshenziswa kwesikhathi eside kwe-NSAID kungaphazamisa ungqimba lwe-phospholipid yendlela yamathumbu. Lokhu kungadala ukulimala kwamathumbu. Ucwaningo lukhombisile ukuthi i-PC ingasiza ekuvikeleni ukulimala kwamathumbu okuhlobene ne-NSAID.

4. Kungasiza ekunciphiseni izimpawu zesilonda esilimaza ulcerative

I-ulcerative colitis ibangela ukuvuvukala emkhakheni wokugaya ukudla. Kungadala nezilonda. Ngokuya ngocwaningo lwango-2010, abantu abane-ulcerative colitis bavame ukuba namazinga we-PC anciphise amathumbu abo emathunjini. Ukwengezwa kungasiza ukuvikela ungqimba lwamafinyila womgudu wokugaya ukudla futhi kunciphise ukuvuvukala.

5. Kungakhuthaza i-lipolysis

I-Lipolysis ukuwohloka kwamafutha emzimbeni. Amafutha amaningi kakhulu angadala ukwakheka kwe-lipomas. I-Lipomas iyizicubu ezibuhlungu, ezinobungozi. Iningi lisuswa ngokuhlinzwa.

Ngokuya nge-a, ukufaka i-PC ku-lipoma kungabulala amaseli ayo anonile futhi kwehlise usayizi wayo. Kudingeka ukutadisha okwengeziwe ukuthola ukuphepha kwesikhathi eside kwalokhu kwelashwa.

6. Kungasiza ukuncibilikisa amatshe enyongo

Ama-Gallstones ayizibambiso ezinzima ku-gallbladder yakho. Zivame ukwenziwa nge-cholesterol engaxutshiwe noma i-bilirubin. Uma kushiywe kungalashwa, kungahle kungene emibhobho yakho ye-bile futhi kubangele ubuhlungu obukhulu noma i-pancreatitis.


Ngokuya ngocwaningo lwango-2003, ukwesekwa kwe-PC kunciphise ukwakheka kwe-cholesterol enyongo kumagundane adlisa ukudla okunamafutha amaningi. Ucwaningo luthole ukuthi lapho amazinga e-PC enyuka, amazinga okugcwala kwe-cholesterol anciphile.

Isetshenziswa kanjani

Kunezinhlobo eziningi ze-PC ongakhetha kuzo, kepha azidaliwe zonke zilingana. Ngoba izithasiselo azilawulwa kahle, kungaba yinselele ukwazi ukuthi ngabe uthola umkhiqizo osezingeni eliphakeme.

Kufanele ukhethe uhlobo lomkhiqizo:

  • yenziwa esikhungweni se-GMP (Imikhuba Emihle Yokukhiqiza)
  • yenziwe ngezithako ezimsulwa
  • iqukethe izithasiselo ezimbalwa noma cha
  • ibala izithako ezisebenzayo nezingasebenzi kwilebula
  • ihlolwa ngumuntu wesithathu

Asikho isincomo somthamo esilinganiselwe se-PC ngezimo eziningi. Umthamo ojwayelekile ungama-milligram angama-840 kuze kube kabili ngosuku, kepha kufanele uhlale wehlisela umthamo owunikezwe kumkhiqizo. Udokotela wakho angakusiza nokuthi unqume isilinganiso esiphephile kuwe.

Imiphumela emibi engaba khona nezingozi

Ukuze unciphise ubungozi bemiphumela emibi, qala ngomthamo ophansi kakhulu ongawuthola futhi kancane kancane usebenze ngendlela yakho kuze kufike kumthamo ogcwele. Qiniseka ukuthi ulandela imihlahlandlela yomkhiqizi noma imiyalo kadokotela wakho.

I-PC yomlomo ingadala ukujuluka okweqile, futhi ukuthatha ngaphezu kuka-30 amagremu nsuku zonke kungadala:

  • isifo sohudo
  • isicanucanu
  • ukuhlanza

Ukujova i-PC ngqo kwisigaxa esinamafutha kungadala ukuvuvukala okukhulu noma i-fibrosis. Kungadala futhi:

  • ubuhlungu
  • evuthayo
  • ukulunywa
  • ukulinyazwa
  • i-edema
  • ukubomvu kwesikhumba

Ukuthatha i-PC nge-AChE inhibitor, njenge-donepezil (Aricept) noma i-tacrine (i-Cognex), kungakhuphula amazinga e-acetylcholine emzimbeni. Lokhu kungadala imiphumela emibi ye-cholinergic, kufaka phakathi:

  • isithuthwane
  • ubuthakathaka bemisipha
  • inhliziyo encane
  • izinkinga zokuphefumula

Ukuthatha i-PC ngezidakamizwa ze-cholinergic noma ze-anticholinergic nakho kungathinta ukusebenza kwazo.

I-PC ayikhonjwanga iphephile kwabesifazane abakhulelwe noma abancelisayo, ngakho-ke akunconywa.

Okubalulekile

I-PC isiza ukusekela imisebenzi eminingi yomzimba wakho, kusuka ku-fat metabolism kuya ekugcineni isakhiwo samaseli. Ungathola okwanele ekudleni okufana namaqanda, inyama ebomvu, nezinhlamvu ezigcwele, futhi imithombo yokudla iyona khetho lokuqala olungcono kakhulu. Izithasiselo ziyindlela yesibili. Khetha umkhiqizo wakho ngemuva kokwenza ucwaningo ngedumela nekhwalithi, njengoba izengezo zingalawulwa yi-U.S. Food and Drug Administration.

Izithasiselo ze-PC zitholakala ngama-capsule namafomu oketshezi ngaphandle kwemithi kadokotela. Kucatshangwa ukuthi ziphephile lapho zisetshenziswa njengoba kuqondiswe isikhathi esifushane. Umjovo we-PC kufanele uhanjiswe ngumsebenzi wezempilo.

Uma ungathanda ukufaka i-PC enkambisweni yakho, khuluma nodokotela wakho. Bangakuhamba ngezinzuzo nezingozi zakho ngazinye, futhi baphendule noma yimiphi imibuzo ongaba nayo.

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