Ukuhlolwa Kweplatelet

-Delile

• Kuyini ukuhlolwa kweplatelet?
• Zisetshenziselwani?
• Kungani ngidinga ukuhlolwa kweplatelet?
• Kwenzekani ngesikhathi sokuhlolwa kweplatelet?
• Ngabe kukhona engizodinga ukukwenza ukulungiselela isivivinyo?
• Ingabe zikhona izingozi esivivinyweni?
• Isho ukuthini imiphumela?
• Ngabe kukhona okunye engidinga ukukwazi mayelana nokuhlolwa kokusebenza kweplatelet?
• Izinkomba

Kuyini ukuhlolwa kweplatelet?

Ama-Platelets, owaziwa nangokuthi ama-thrombocyte, amangqamuzana egazi amancane abalulekile ekunqandeni igazi. Ukuvala inqubo ekusiza ukuthi uyeke ukopha ngemuva kokulimala. Kunezinhlobo ezimbili zokuhlolwa kweplatelet: ukuhlolwa kweplatelet count kanye nokuhlolwa kokusebenza kweplatelet.

Ukuhlolwa kokubalwa kweplatelet ulinganisa inani lamagazi egazini lakho. Ukubalwa kweplatelet okuphansi kunokujwayelekile kubizwa ngokuthi i-thrombocytopenia. Lesi simo singadala ukuthi wophe kakhulu ngemuva kokusikwa noma okunye ukulimala okubangela ukopha. Ukubalwa kweplatelet ephakeme kunokujwayelekile kubizwa ngokuthi i-thrombocytosis. Lokhu kungenza igazi lakho livale ngaphezu kwalokho okudingayo. Amahlule egazi angaba yingozi ngoba angavimba ukuhamba kwegazi.

Ukuhlolwa komsebenzi wePlatelet hlola amandla wakho weplatelets ukwakha amahlule. Ukuhlolwa komsebenzi wePlatelet kufaka:

• Isikhathi sokuvala. Lokhu kuhlolwa kukala isikhathi esithatha ama-platelet esampula yegazi ukufaka imbobo encane kushubhu elincane. Kuyasiza ukubukeka kokuphazamiseka kweplatelet okuhlukile.
• I-Viscoelastometry. Lokhu kuhlolwa kukala amandla ehlule legazi njengoba lenzeka. Ihlule legazi kufanele liqine ukuze liyeke ukopha.
• I-platelet aggregometry. Leli yiqembu lezivivinyo ezisetshenziselwa ukukala ukuthi amaplatelet ahlangana kanjani (ahlanganisiwe).
• I-Lumiaggregometry. Lokhu kuhlolwa kukala inani lokukhanya elikhiqizwayo lapho kunezelwa izinto ezithile kusampula yegazi. Kungasiza ukukhombisa uma kukhona ukukhubazeka kuma-platelets.
• Ukugeleza kwe-cytometry. Lesi isivivinyo esisebenzisa ama-lasers ukubheka amaprotheni ebusweni bama-platelet. Kungasiza ukuxilonga ukuphazamiseka kweplatelet. Lokhu ukuhlolwa okukhethekile. Itholakala kuphela ezibhedlela ezithile nasemalabhorethri.
• Isikhathi sokopha. Lokhu kuhlolwa kukala inani lesikhathi sokuphuma kwegazi ukumisa ngemuva kokusikeka okuncane engalweni. Kwake kwasetshenziswa kakhulu ukuvivinya izifo ezahlukahlukene zeplatelet. Manje, ezinye izivivinyo zomsebenzi weplatelet zisetshenziswa kaningi. Ukuhlolwa okusha kunikela ngemiphumela ethembeke kakhudlwana.

Amanye amagama: ukubalwa kweplatelet, ukubalwa kwe-thrombocyte, ukuhlolwa komsebenzi weplatelet, ukuhlolwa kweplatelet function, izifundo zokuhlanganiswa kweplatelet

Zisetshenziselwani?

Ukubalwa kweplatelet kuvame ukusetshenziselwa ukuqapha noma ukuxilonga izimo ezibangela ukopha kakhulu noma ukujiya kakhulu. Ukubalwa kweplatelet kungabalwa ekubaleni okuphelele kwegazi, isivivinyo esivame ukwenziwa njengengxenye yokuhlolwa okujwayelekile.

Ukuhlolwa komsebenzi wePlatelet kungasetshenziselwa:

• Siza ukuxilonga izifo ezithile zeplatelet
• Hlola ukusebenza kweplatelet ngesikhathi senqubo eyinkimbinkimbi yokuhlinzwa, efana nokudlula kwenhliziyo nokuhlinzwa kokuhlukumezeka. Lezi zinhlobo zezinqubo zinengozi eyengeziwe yokopha.
• Hlola iziguli ngaphambi kokuhlinzwa, uma zinomlando womuntu siqu noma womndeni wezifo zokopha
• Gada abantu abathatha izinciphisi zegazi. Le mithi inganikezwa ukunciphisa ukujiya kwabantu abasengozini yokuhlaselwa yisifo senhliziyo noma isifo sohlangothi.

Kungani ngidinga ukuhlolwa kweplatelet?

Ungadinga ukubalwa kweplatelet kanye / noma ukusebenza kweplatelet uma unezimpawu zokuba nama-platelet ambalwa kakhulu noma amaningi kakhulu.

Izimpawu zamaplatelet ambalwa kakhulu zifaka:

• Ukopha isikhathi eside ngemuva kokusikwa okuncane noma ukulimala
• Ukopha ngamakhala
• Ukulimala okungachazeki
• Khomba izindawo ezibomvu ezilinganiselwe esikhunjeni, ezaziwa njenge-petechiae
• Amabala ansundu esikhunjeni, aziwa ngokuthi yi-purpura. Lokhu kungabangelwa ukopha ngaphansi kwesikhumba.
• Isikhathi esinzima kanye / noma esinde sokuya esikhathini

Izimpawu zamaplatelet amaningi kakhulu zifaka:

• Ubuntofontofo bezandla nezinyawo
• Ubuhlungu bekhanda
• Isiyezi
• Ubuthakathaka

Ungadinga nokuhlolwa kokusebenza kweplatelet uma:

• Ukwenza ukuhlinzwa okuyinkimbinkimbi
• Ukuthatha imithi ukunciphisa ukujiya

Kwenzekani ngesikhathi sokuhlolwa kweplatelet?

Ukuhlolwa okuningi kweplatelet kwenziwa kusampula yegazi.

Ngesikhathi sokuhlolwa, uchwepheshe wezokunakekelwa kwempilo uzothatha isampuli yegazi emthanjeni osengalweni yakho, esebenzisa inaliti encane. Ngemuva kokuthi kufakwe inaliti, kuzoqoqwa inani elincane legazi kufakwe ithubhu yokuhlola noma isitsha. Ungase uzizwe uluma kancane lapho inaliti ingena noma iphuma. Lokhu ngokuvamile kuthatha imizuzu engaphansi kwemihlanu.

Ngabe kukhona engizodinga ukukwenza ukulungiselela isivivinyo?

Awudingi amalungiselelo akhethekile wokuhlolwa kokubalwa kweplatelet

Uma uthola ukuhlolwa komsebenzi weplatelet, kungadingeka ukuthi uyeke ukuthatha imishanguzo ethile, njenge-aspirin ne-ibuprofen, ngaphambi kokuhlolwa kwakho. Umhlinzeki wakho wezokunakekelwa kwempilo uzokwazisa uma ngabe kukhona imiyalelo ekhethekile ongayilandela.

Ingabe zikhona izingozi esivivinyweni?

Kunengozi encane kakhulu yokuhlolwa kwegazi. Ungaba nobuhlungu obuncane noma ukulimaza lapho kufakwe khona inaliti, kepha izimpawu eziningi ziyaphela ngokushesha.

Isho ukuthini imiphumela?

Uma imiphumela yakho ikhombisa isibalo seplatelet esiphansi kunokujwayelekile (i-thrombocytopenia), ingahle ikhombise:

• Umdlavuza othinta igazi, njenge-leukemia noma i-lymphoma
• Ukutheleleka ngegciwane, njenge-mononucleosis, i-hepatitis, noma isimungumungwane
• Isifo sokuzivikela komzimba. Lesi yisifo esidala ukuthi umzimba uhlasele izicubu zaso ezinempilo, ezingafaka ama-platelets.
• Ukutheleleka noma ukulimala kumnkantsha wethambo
• Isifo sokuqina kwesibindi
• Ukuntuleka kwe-Vitamin B12
• I-Gestational thrombocytopenia, isimo esivamile, kodwa esimnene, esineplatelet esithinta abesifazane abakhulelwe. Akwaziwa ukuthi kungadala muphi umonakalo kumama noma enganeni yakhe engakazalwa. Imvamisa iba ngcono yodwa ngesikhathi sokukhulelwa noma ngemuva kokubeletha.

Uma imiphumela yakho ikhombisa isibalo seplatelet esiphezulu kunokujwayelekile (i-thrombocytosis), ingakhombisa:

• Izinhlobo ezithile zomdlavuza, njengomdlavuza wamaphaphu noma umdlavuza webele
• Ukushoda kwegazi
• Isifo samathumbu esivuthayo
• Isifo samathambo
• Ukutheleleka ngegciwane noma ngegciwane

Uma imiphumela yakho yokuhlolwa kweplatelet ibingejwayelekile, kungasho ukuthi unenkinga yeplatelet oyizuze njengefa noma oyitholile. Izinkinga ezizuzwe njengefa ziyadluliselwa zisuka emndenini wakho. Izimo zikhona lapho kuzalwa, kepha kungenzeka ungabi nazo izimpawu uze ube mdala. Izinkinga ezitholakele azikho lapho kuzalwa. Kungabangelwa ezinye izifo, imithi, noma ukuvezwa emvelweni. Kwesinye isikhathi imbangela ayaziwa.

Izinkinga zeplatelet ezizuzwe njengefa zifaka:

• Isifo i-Von Willebrand, isifo sofuzo esinciphisa ukukhiqizwa kwama-platelet noma senza ukuthi ama-platelet asebenze kancane. Kungadala ukopha ngokweqile.
• I-thrombasthenia kaGlanzmann, ukuphazamiseka okuthinta ikhono leplatelet lokuhlangana ndawonye
• I-Bernard-Soulier syndrome, esinye isifo esithinta ikhono lama-platelets lokuhlangana ndawonye
• Isifo se-storage pool, isimo esithinta ikhono lama-platelets lokukhipha izinto ezisiza ama-platelets ahlangane

Ukuphazamiseka kweplatelet okutholakele kungahle kube ngenxa yezifo ezingamahlalakhona njenge:

• Ukuhluleka kwezinso
• Izinhlobo ezithile ze-leukemia
• I-Myelodysplastic syndrome (MDS), isifo somnkantsha wamathambo

Ngabe kukhona okunye engidinga ukukwazi mayelana nokuhlolwa kokusebenza kweplatelet?

Ukuhlolwa kweplatelet kwesinye isikhathi kwenziwa kanye nokuhlolwa kwegazi okukodwa noma okuningi:

• Ukuhlolwa kwegazi le-MPV, elikala ubukhulu bama-platelet akho
• Ukuhlolwa kwesikhashana kwe-thromboplastin time (PTT), okulinganisa isikhathi esisithathayo ukuze igazi livalwe
• Isikhathi se-Prothrombin ne-INR, esihlola amandla omzimba okwakha amahlule egazi

Izinkomba

1. Umtholampilo waseCleveland [Inthanethi]. I-Cleveland (OH): Umtholampilo waseCleveland; c2020. I-Thrombocytopenia: Ukubuka konke; [kucashunwe ngo-2020 Okthoba 25]; [cishe izikrini ezi-3]. Kutholakala kusuka: https://my.clevelandclinic.org/health/diseases/14430-thrombocytopenia
2. I-ClinLab Navigator [Inthanethi]. I-ClinLab Navigator; c2020. Platelet Umsebenzi Screen; [kucashunwe ngo-2020 Okthoba 25]; [cishe izikrini ezi-2]. Kutholakala kusuka: http://www.clinlabnavigator.com/platelet-function-screen.html
3. IGernsheimer T, uJames AH, uStasi R. Ngiyiphatha kanjani i-thrombocytopenia ekukhulelweni. Igazi. [Inthanethi]. 2013 Jan 3 [icashunwe ngo-2020 Nov 20]; 121 (1): 38-47. Kutholakala kusuka: https://pubmed.ncbi.nlm.nih.gov/23149846
4. Ukuhlolwa Kwelebhu Ku-inthanethi [i-Intanethi]. IWashington DC: I-American Association for Clinical Chemistry; c2001-2020. Ukuphazamiseka Kokuvalwa Okudlulele; [kubuyekezwe i-2019 Oct 29; kucashunwe ngo-2020 Okthoba 25]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://labtestsonline.org/conditions/excessive-clotting-disorders
5. Ukuhlolwa Kwelebhu Ku-inthanethi [i-Intanethi]. IWashington DC: I-American Association for Clinical Chemistry; c2001-2020. I-Myelodysplastic Syndrome; [kubuyekezwe i-2019 Nov 11; kucashunwe ngo-2020 Okthoba 25]; [cishe izikrini ezi-2]. Kutholakala ku: https://labtestsonline.org/conditions/myelodysplastic-syndrome
6. Ukuhlolwa Kwelebhu Ku-inthanethi [i-Intanethi]. IWashington DC: I-American Association for Clinical Chemistry; c2001-2020. Isikhathi Esingafani Se-Thromboplastin Time (PTT, aPTT); [kubuyekezwe ngo-2020 Sep 22; kukhonjiwe ngo-2020 Okthoba 25]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://labtestsonline.org/tests/partial-thromboplastin-time-ptt-aptt
7. Ukuhlolwa Kwelebhu Ku-inthanethi [i-Intanethi]. IWashington DC: I-American Association for Clinical Chemistry; c2001-2020. Ukubalwa Kweplatelet; [kubuyekezwe u-2020 Aug 12; kucashunwe ngo-2020 Okthoba 25]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://labtestsonline.org/tests/platelet-count
8. Ukuhlolwa Kwelebhu Ku-inthanethi [i-Intanethi]. IWashington DC: I-American Association for Clinical Chemistry; c2001-2020. Ukuhlolwa Komsebenzi wePlatelet; [kubuyekezwe ngo-2020 Sep 22; kucashunwe ngo-2020 Okthoba 25]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://labtestsonline.org/tests/platelet-function-tests
9. Ukuhlolwa Kwelebhu Ku-inthanethi [i-Intanethi]. IWashington DC: I-American Association for Clinical Chemistry; c2001-2020. Isikhathi se-Prothrombin kanye ne-International Normalized Ratio (PT / INR); [kubuyekezwe ngo-2020 Sep 22; kucashunwe ngo-2020 Okthoba 25]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://labtestsonline.org/tests/prothrombin-time-and-international-normalized-ratio-ptinr
10. I-MFM [Inthanethi] ENew York: Ababambisene Nama-Fetal Medicine Associates; c2020. ITromocytopenia nokukhulelwa; 2017 Feb 2 [icashunwe ngo-2020 Nov 20]; [cishe izikrini ezi-3]. Kutholakala kusuka: https://www.mfmnyc.com/blog/thrombocytopenia-during-pregnancy
11. I-National Heart, Lung, ne-Blood Institute [i-Intanethi]. I-Bethesda (MD): UMnyango Wezempilo kanye Nezinsizakalo Zabantu e-U.S. Ukuhlolwa Kwegazi; [kucashunwe ngo-2020 Okthoba 25]; [cishe izikrini ezi-3]. Kutholakala kusuka: https://www.nhlbi.nih.gov/health-topics/blood-tests
12. I-NIH National Human Genome Research Institute [i-Intanethi]. I-Bethesda (MD): UMnyango Wezempilo kanye Nezinsizakalo Zabantu e-U.S. Ukuphazamiseka Kofuzo; [kubuyekezwe i-2018 Meyi 18; kukhonjiwe ngo-2020 Nov 20]; [cishe izikrini ezi-3]. Kutholakala kusuka: https://www.genome.gov/For-Patients-and-Families/Genetic-Disorders
13. I-Paniccia R, i-Priora R, i-Liotta AA, i-Abbate R. Platelet izivivinyo zomsebenzi: ukubuyekezwa kokuqhathanisa. IVasc Health Risk Manag [Inthanethi]. I-2015 Feb 18 [icashunwe ngo-2020 Oct 25]; 11: 133-48. Kutholakala kusuka: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340464
14. Izifo ze-Parikh F. kanye ne-Thrombocytopenia. J Assoc Odokotela eNdiya. [Inthanethi]. 2016 Feb [icashunwe ngo-2020 Nov 20]; 64 (2): 11-12. Kutholakala kusuka: https://pubmed.ncbi.nlm.nih.gov/27730774/
15. Impilo Yezingane zikaRiley: I-Indiana University Health [Internet]. I-Indianapolis: Isibhedlela iRiley Sezingane e-Indiana University Health; c2020. Ukuphazamiseka Kwe-Coagulation; [kucashunwe ngo-2020 Okthoba 25]; [cishe izikrini ezi-3]. Kutholakala kusuka: https://www.rileychildrens.org/health-info/coagulation-disorders
16. I-University of Rochester Medical Center [i-Inthanethi]. URochester (NY): Isikhungo Sezokwelapha sase-University of Rochester; c2020. I-Health Encyclopedia: Amaplatelets; [kucashunwe ngo-2020 Okthoba 25]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=platelet_count
17. I-University of Rochester Medical Center [i-Inthanethi]. URochester (NY): Isikhungo Sezokwelapha sase-University of Rochester; c2020. I-Health Encyclopedia: Ayini Ama-Platelet ?; [kucashunwe ngo-2020 Okthoba 25]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://www.urmc.rochester.edu/encyclopedia/content.aspx?ContentTypeID=160&ContentID=36
18. Impilo ye-UF: University of Florida Health [Internet]. IGainesville (FL): Inyuvesi yaseFlorida Impilo; c2020. Ukubalwa kweplatelet: Ukubuka konke; [kubuyekezwe ngo-2020 Okthoba 23; kukhonjiwe ngo-2020 Okthoba 25]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://ufhealth.org/platelet-count
19. Impilo ye-UF: University of Florida Health [Internet]. IGainesville (FL): Inyuvesi yaseFlorida Impilo; c2020. I-Thrombocytopenia: Ukubuka konke; [kubuyekezwe ngo-2020 Novemba 20; kukhonjiwe ngo-2020 Nov 20]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://ufhealth.org/thrombocytopenia

Imininingwane ekulesi siza akufanele isetshenziswe esikhundleni sezokunakekelwa kwezokwelapha noma iseluleko. Xhumana nomhlinzeki wezempilo uma unemibuzo ngempilo yakho.