Amakhambi amakhulu asetshenziselwa i-reflux ye-gastroesophageal

-Delile

• 1. Ama-Antacids
• 2. Izivimbeli zokukhiqiza i-asidi
• Proton pump inhibitors
• Abaphikisi be-Histamine H2 receptor
• 3. Ama-Accelerators wokukhipha isisu
• 4. Abavikeli besisu

Enye yezindlela zokwelapha i-reflux ye-gastroesophageal ukunciphisa i-asidi yokuqukethwe kwesisu, ukuze ingalimazi i-esophagus. Ngakho-ke uma i-reflux ingaphansi kwe-asidi izoshisa kancane futhi idale izimpawu ezimbalwa.

Imithi engasetshenziswa ngama-antacids, inhibitors yokukhiqizwa kwe-asidi, izivikeli zesisu kanye nama-accelerators wokukhipha isisu.

1. Ama-Antacids

Ama-antacids asetshenziswa kakhulu ukunciphisa i-hydrochloric acid esiswini yi-aluminium hydroxide, i-magnesium hydroxide ne-sodium bicarbonate. La makhambi ayizisekelo ezisabela ngama-acid, anciphisa amandla awo anobuthi futhi anikeze amanzi nosawoti.

Ama-antiacid awasetshenziswa kaningi ngoba awasebenzi kahle futhi ngoba kungenzeka ukuthi kube nomphumela obuyayo, okungukuthi, umuntu uyathuthuka ngokushesha kepha lapho-ke kungahle kube nokubi.

Imiphumela emibi kakhulu yale mithi ukuqunjelwa, okubangelwa osawoti be-aluminium, noma isifo sohudo esibangelwa ama-antacids aqukethe i-magnesium, njengoba edala umphumela we-osmotic emathunjini. Ukunciphisa le miphumela emibi, ama-antacids asetshenziswa kakhulu ukuhlanganiswa kwe-magnesium hydroxide ne-aluminium.

2. Izivimbeli zokukhiqiza i-asidi

Ama-inhibitor wokukhiqiza i-acid amakhambi asetshenziswa kakhulu ekwelapheni i-reflux ye-gastroesophageal, futhi angavimbela lo mkhiqizo ngezindlela ezimbili:

Proton pump inhibitors

Lawa ngamakhambi ayinhloko asetshenziselwa ukwelapha izifo ezihlobene nokwanda kwe-gastric acid secretion. Esetshenziswa kakhulu yi-omeprazole, i-pantoprazole, i-esomeprazole ne-rabeprazole, ephazamisa iphampu ye-proton, evimbela ukukhiqizwa kwe-hydrochloric acid esiswini.

Imiphumela emibi kakhulu engenzeka ngokusetshenziswa kwale mithi yikhanda, isifo sohudo, ukuqubuka, ubuhlungu besisu, ukuqunjelwa, isicanucanu nokuqunjelwa.

Abaphikisi be-Histamine H2 receptor

Le mithi ivimbela uketshezi lwe-asidi olubangelwa yi-histamine ne-gastrin kanti okusetshenziswa kakhulu yi-cimetidine, nizatidine ne-famotidine.

Imiphumela emibi kakhulu edalwa ukusetshenziswa kwale mithi uhudo, ikhanda, ukozela, ukukhathala, ubuhlungu bemisipha nokuqunjelwa

3. Ama-Accelerators wokukhipha isisu

Lapho isisu sigcwele kakhulu, kungenzeka ukuthi i-reflux ye-gastroesophageal yenzeke.Ngakho-ke, ukugwema lokhu, ukuhamba kwamathumbu emathunjini kungakhuthazwa ngamakhambi weprokinetic afana ne-metoclopramide, i-domperidone noma i-cisapride esiza ukukhipha isisu, ngaleyo ndlela kunciphise isikhathi ukudla okuhlala esiswini, kuvimbele i-reflux.

Imiphumela emibi kakhulu engenzeka ngokusetshenziswa kwe-metoclopramide ukozela, ukuzwa ubuthakathaka, ukuphazamiseka, umfutho wegazi ophansi kanye nohudo. Ngaphezu kwalokho, yize kungavamile, ukuphazamiseka kwamathumbu kungenzeka ngokusetshenziswa kwe-domperidone ne-cisapride.

4. Abavikeli besisu

Izivikeli zesisu zingasetshenziswa ukwelapha i-reflux yesisu, evikela i-esophagus, evimbela ukushiswa lapho okuqukethwe esiswini kudlula kuye.

Ngokuvamile, umzimba unendlela lapho uveza khona amafinyila avikela ulwelwesi lwesisu, uvimbele i-asidi ekuyihlaseleni, kepha kwezinye izindawo zokugula nangokusetshenziswa kwemithi ethile, ukukhiqizwa kwale mucus kungancipha futhi kunikeze ukuhlukunyezwa yomunyu. Izivikeli zesisu ezingasetshenziswa ukufaka lesi sikhwehlela ngosawoti be-sucralfate kanye ne-bismuth abathuthukisa izindlela zokuzivikela zesisu futhi bakhe umgoqo wokuzivikela esiswini nasesimophweni.

Imiphumela emibi kakhulu edalwa wusawoti we-bismuth ukufiphazwa kwendle, isiyezi, ikhanda, isicanucanu, ukuhlanza, isifo sohudo nokuphazamiseka kwengqondo.

I-Sucralfate ivame ukubekezelelwa kahle futhi umphumela wayo oyinhloko ukuqunjelwa. Kodwa-ke, kungadala nomlomo owomile, isicanucanu, ukuhlanza, ikhanda nokuqubuka kwesikhumba.

Kukhona namakhambi asekhaya angaba nomthelela ekwelashweni okuyimpumelelo. Thola ukuthi iziphi ezisetshenziswa kakhulu.