I-Goodpasture syndrome: kuyini, izimpawu, izimbangela nokwelashwa
-Delile
IGoodpasture Syndrome yisifo esingajwayelekile sokuzivikela komzimba, lapho amangqamuzana omzimba okuvikela ahlasela izinso namaphaphu, ikakhulu okudala izimpawu ezinjengokukhwehlela okunegazi, ukuphefumula kanzima nokuphuma kwegazi emchameni.
Lesi sifo senzeka ngenxa yokuba khona kwama-antibody ahlasela amangqamuzana ezinso namaphaphu. Ezinye izinto ezibonakala zandisa ubungozi bokuhlaselwa yilesi sifo yilezi: ukuba nomlando walesi sifo nokubhema, ukuba nezifo eziphindaphindayo zokuphefumula nokuchayeka ekuphefumuleni izinto ezifana ne-methane noma i-propane, isibonelo.
Ukwelashwa kusekelwe ekusetshenzisweni kwemithi efana ne-immunosuppressants kanye ne-corticosteroids, kepha ezimweni ezinzima kakhulu, i-plasmapheresis noma i-hemodialysis kungadingeka.
Izimpawu eziyinhloko
Izimpawu eziyinhloko zeGoodpasture Syndrome yilezi:
- Ukukhathala ngokweqile;
- Ukukhwehlela igazi;
- Kunzima ukuphefumula;
- Ubuhlungu lapho uphefumula;
- Izinga lenyuka le-urea egazini;
- Ubukhona begazi kanye / noma igwebu emchameni;
- Ukushisa lapho uchama.
Lapho kuvela izimpawu, kunconywa ukuthi ufune usizo lwezokwelashwa ngokushesha ukuze uthole izivivinyo kanye nenkomba yokwelashwa okufanele kakhulu, ngoba izimpawu zingase zibe zimbi uma lesi sifo singelashwa kusenesikhathi.
Ngaphezu kwalokho, ezinye izifo zingaba nezimpawu ezicishe zifane nalesi sifo, njenge-Wegener granulomatosis, eyenza ukuxilongwa kube nzima. Zazi izimpawu nokuthi ungayelapha kanjani i-Wegener's granulomatosis.
Ungakuqinisekisa kanjani ukuxilongwa
Ukuthola i-Goodpasture's syndrome, udokotela uzohlola umlando wakho wezempilo nobude bezimpawu zakho. Ngemuva kwalokho, udokotela angayalela ezinye izivivinyo, njengokuhlolwa kwegazi nomchamo, ukuthola amasosha omzimba akhiqizwa ngumzimba abangela i-Goodpasture's syndrome.
njenge-biopsy yezinso, okungukukhishwa kwengxenye encane yezicubu zezinso, ukubona ukuthi ngabe kukhona yini amaseli abangela i-Goodpasture's syndrome.
Ngaphezu kwalokho, udokotela futhi anga-oda ezinye izivivinyo, njenge-biopsy yezinso, equkethe ukususa ingxenye encane yezicubu zezinso ezizohlolwa elabhoratri, ukuze kubonakale ukuthi ngabe kukhona yini amaseli abangela i-Goodpasture's syndrome.
Ama-X-ray nama-CT scan nawo anga-odolwa ngudokotela wakho ukuthola ukulimala kwamaphaphu. Bona imininingwane eminingi yokuthi i-computed tomography yenziwa kanjani.
Izimbangela ezingaba khona
Isizathu se-Goodpasture's syndrome singenxa yama-anti-GBM antibodies ahlasela ingxenye ye-NC-1 yohlobo IV collagen kumaseli ezinso namaphaphu.
Lesi sifo sibonakala sivame kakhulu kwabesilisa kunabesifazane, phakathi kweminyaka engama-20 nengama-30 ubudala, nakubantu abanesikhumba esikhanyayo. Ngaphezu kwalokho, ukuvezwa kumakhemikhali afana nezibulala-zinambuzane, intuthu kagwayi, kanye nezifo ezibangelwa amagciwane kungezinye zezinto ezibonakala zikhulisa ubungozi bokuba ne-syndrome, njengoba zingenza amangqamuzana omzimba okuvikela ahlasele amaphaphu namaphaphu.
Yelashwa kanjani
Ukwelashwa kweGoodpasture's Syndrome kuvame ukwenziwa esibhedlela futhi kusekelwe ekusetshenzisweni kwemithi yokuvikela ukuzivikela kanye ne-corticosteroids, evikela amaseli omzimba okuvikela izinso namaphaphu.
Kwezinye izimo, ukwelashwa nge-plasmapheresis kuyakhonjiswa, okuyinqubo ehlunga igazi futhi ehlukanise amasosha omzimba ayingozi ezinso nasemaphashini. Uma izinso zithinteke kakhulu, i-hemodialysis noma ukufakelwa izinso kungadingeka. Ukuqonda okungcono ukuthi yini i- plasmapheresis nokuthi kwenziwa kanjani.
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